JP2013542955A5 - - Google Patents

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Publication number
JP2013542955A5
JP2013542955A5 JP2013537733A JP2013537733A JP2013542955A5 JP 2013542955 A5 JP2013542955 A5 JP 2013542955A5 JP 2013537733 A JP2013537733 A JP 2013537733A JP 2013537733 A JP2013537733 A JP 2013537733A JP 2013542955 A5 JP2013542955 A5 JP 2013542955A5
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JP
Japan
Prior art keywords
agent
compound
hcv
compound according
drug
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2013537733A
Other languages
English (en)
Japanese (ja)
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JP2013542955A (ja
JP5828903B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2011/058404 external-priority patent/WO2012061248A2/en
Publication of JP2013542955A publication Critical patent/JP2013542955A/ja
Publication of JP2013542955A5 publication Critical patent/JP2013542955A5/ja
Application granted granted Critical
Publication of JP5828903B2 publication Critical patent/JP5828903B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2013537733A 2010-11-01 2011-10-28 新規特異的hcv ns3プロテアーゼ阻害剤 Expired - Fee Related JP5828903B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US40898910P 2010-11-01 2010-11-01
US61/408,989 2010-11-01
PCT/US2011/058404 WO2012061248A2 (en) 2010-11-01 2011-10-28 Novel specific hcv ns3 protease inhibitors

Publications (3)

Publication Number Publication Date
JP2013542955A JP2013542955A (ja) 2013-11-28
JP2013542955A5 true JP2013542955A5 (OSRAM) 2015-02-12
JP5828903B2 JP5828903B2 (ja) 2015-12-09

Family

ID=46025037

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2013537733A Expired - Fee Related JP5828903B2 (ja) 2010-11-01 2011-10-28 新規特異的hcv ns3プロテアーゼ阻害剤

Country Status (10)

Country Link
US (1) US8729014B2 (OSRAM)
EP (1) EP2635570B1 (OSRAM)
JP (1) JP5828903B2 (OSRAM)
CN (1) CN103328466B (OSRAM)
AU (1) AU2011323658A1 (OSRAM)
BR (1) BR112013010836A2 (OSRAM)
CA (1) CA2815855C (OSRAM)
IL (1) IL225908A0 (OSRAM)
MX (1) MX2013004906A (OSRAM)
WO (1) WO2012061248A2 (OSRAM)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112012033022A2 (pt) 2010-06-24 2016-12-20 Genosciense Pharma Sas tratamento de vírus de hepatite c relacionado a doenças utilizando hidroxicloroquina ou uma combinação de hidroxicloroquina e um agente antiviral
EP2635570B1 (en) 2010-11-01 2017-12-13 RFS Pharma, LLC. Novel specific hcv ns3 protease inhibitors
WO2012176149A1 (en) 2011-06-23 2012-12-27 Panmed Ltd. Treatment of hepatitis c virus
CN104039774A (zh) 2012-01-12 2014-09-10 Rfs制药公司 Hcv ns3蛋白酶抑制剂
UA119315C2 (uk) 2012-07-03 2019-06-10 Гіліад Фармассет Елелсі Інгібітори вірусу гепатиту с
SG11201507223TA (en) 2013-03-15 2015-10-29 Gilead Sciences Inc Macrocyclic and bicyclic inhibitors of hepatitis c virus
US9926295B2 (en) * 2014-04-15 2018-03-27 Cocrystal Pharma, Inc. Potent and selective inhibitors of hepatitis C virus
CN105315261A (zh) * 2014-08-04 2016-02-10 正大天晴药业集团股份有限公司 Hcv ns3蛋白酶抑制剂的钠盐

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995000536A1 (en) 1993-06-22 1995-01-05 Fujisawa Pharmaceutical Co., Ltd. Peptide compounds
CZ298749B6 (cs) 1996-10-18 2008-01-16 Vertex Pharmaceuticals Incorporated Inhibitory serinových proteáz a farmaceutické prostředky s jejich obsahem
US6767991B1 (en) 1997-08-11 2004-07-27 Boehringer Ingelheim (Canada) Ltd. Hepatitis C inhibitor peptides
JP4806154B2 (ja) 2000-04-03 2011-11-02 バーテックス ファーマシューティカルズ インコーポレイテッド セリンプロテアーゼ、特にc型肝炎ウイルスns3プロテアーゼのインヒビター
CA2462200A1 (en) 2001-08-10 2003-02-20 Palatin Technologies, Inc. Peptidomimetics of biologically active metallopeptides
MY140680A (en) 2002-05-20 2010-01-15 Bristol Myers Squibb Co Hepatitis c virus inhibitors
WO2004032827A2 (en) 2002-05-20 2004-04-22 Bristol-Myers Squibb Company Hepatitis c virus inhibitors
BRPI0412502A (pt) 2003-07-10 2006-09-19 Achillion Pharmaceuticals Inc derivados de ariltiouréia substituìda úteis como inibidores de replicação viral
KR20120090077A (ko) 2004-01-30 2012-08-16 얀센 알 앤드 디 아일랜드 Hcv ns?3 세린 프로테아제 저해제
CN1984922A (zh) 2004-05-20 2007-06-20 先灵公司 用作丙型肝炎病毒ns3丝氨酸蛋白酶抑制剂的取代脯氨酸
US7323447B2 (en) 2005-02-08 2008-01-29 Bristol-Myers Squibb Company Hepatitis C virus inhibitors
WO2006111906A2 (en) 2005-04-19 2006-10-26 Philips Intellectual Property & Standards Gmbh Illumination system comprising a red-emitting ceramic luminescence converter
TWI387603B (zh) 2005-07-20 2013-03-01 Merck Sharp & Dohme Hcv ns3蛋白酶抑制劑
KR20080036598A (ko) 2005-08-01 2008-04-28 머크 앤드 캄파니 인코포레이티드 Hcv ns3 프로테아제 억제제로서의 마크로사이클릭펩티드
JP2009524681A (ja) 2006-01-27 2009-07-02 フェノミックス コーポレーション C型肝炎ウイルスセリンプロテアーゼインヒビターおよびそのための使用
CN101495457A (zh) * 2006-07-05 2009-07-29 因特蒙公司 C型肝炎病毒复制的新颖抑制剂
KR20090024834A (ko) * 2006-07-05 2009-03-09 인터뮨, 인크. C형 간염 바이러스 복제의 신규 억제제
US7635683B2 (en) 2006-08-04 2009-12-22 Enanta Pharmaceuticals, Inc. Quinoxalinyl tripeptide hepatitis C virus inhibitors
CN101553170B (zh) 2006-11-24 2011-11-09 株式会社岛津制作所 X射线透视摄影装置
US20080287449A1 (en) 2007-04-26 2008-11-20 Deqiang Niu Aza-tripeptide hepatitis c serine protease inhibitors
CA2708150A1 (en) * 2007-12-05 2009-06-18 Enanta Pharmaceuticals, Inc. Fluorinated tripeptide hcv serine protease inhibitors
CA2710144A1 (en) * 2007-12-21 2009-07-02 Avila Therapeutics, Inc. Hcv protease inhibitors and uses thereof
US8293705B2 (en) 2007-12-21 2012-10-23 Avila Therapeutics, Inc. HCV protease inhibitors and uses thereof
KR20110005869A (ko) 2008-04-15 2011-01-19 인터뮨, 인크. C형 간염 바이러스 복제의 신규한 마크로사이클릭 억제제
KR101781789B1 (ko) * 2010-01-27 2017-09-26 에이비 파르마 리미티드. C형 간염 바이러스 억제제로 사용되는 다환 헤테로사이클릭 화합물
EP2635570B1 (en) 2010-11-01 2017-12-13 RFS Pharma, LLC. Novel specific hcv ns3 protease inhibitors

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