JP2013542794A - 固定用量を投与するための薬用モジュール - Google Patents
固定用量を投与するための薬用モジュール Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
- A61M5/281—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle using emptying means to expel or eject media, e.g. pistons, deformation of the ampoule, or telescoping of the ampoule
- A61M5/283—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle using emptying means to expel or eject media, e.g. pistons, deformation of the ampoule, or telescoping of the ampoule by telescoping of ampoules or carpules with the syringe body
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- A—HUMAN NECESSITIES
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M5/2066—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically comprising means for injection of two or more media, e.g. by mixing
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M5/2422—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic using emptying means to expel or eject media, e.g. pistons, deformation of the ampoule, or telescoping of the ampoule
- A61M5/2425—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic using emptying means to expel or eject media, e.g. pistons, deformation of the ampoule, or telescoping of the ampoule by compression of deformable ampoule or carpule wall
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M5/2448—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic comprising means for injection of two or more media, e.g. by mixing
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31596—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing
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- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3294—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles comprising means for injection of two or more media, e.g. by mixing
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- A—HUMAN NECESSITIES
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M2005/1787—Syringes for sequential delivery of fluids, e.g. first medicament and then flushing liquid
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- A—HUMAN NECESSITIES
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M5/2455—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened
- A61M5/2466—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened by piercing without internal pressure increase
- A61M2005/247—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened by piercing without internal pressure increase with fixed or steady piercing means, e.g. piercing under movement of ampoule
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
- A61M2005/31516—Piston or piston-rod constructions, e.g. connection of piston with piston-rod reducing dead-space in the syringe barrel after delivery
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
- A61M5/321—Means for protection against accidental injuries by used needles
- A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
- A61M5/3245—Constructional features thereof, e.g. to improve manipulation or functioning
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- A—HUMAN NECESSITIES
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- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
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- A61M5/321—Means for protection against accidental injuries by used needles
- A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
- A61M5/326—Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user
- A61M2005/3267—Biased sleeves where the needle is uncovered by insertion of the needle into a patient's body
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M5/2033—Spring-loaded one-shot injectors with or without automatic needle insertion
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M5/2455—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
- A61M5/321—Means for protection against accidental injuries by used needles
- A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
- A61M5/326—Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user
Abstract
Description
該薬物送達デバイスが第1の薬剤を含んでなる、上記薬物送達デバイスに取り付けのために構成されるハウジング、
上記ハウジング内に含まれる折り畳みリザーバ、
上記折り畳みリザーバ内に含まれる所定体積の第2の薬剤、
該針配置が上記折り畳みリザーバ及び上記薬物送達デバイスと流体連通して配置される、上記ハウジング内に構成される針配置、
及び上記ハウジング内に部分的に構成されるニードルシュラウドを含んでなり、ここで該ニードルシュラウドは、上記折り畳みリザーバを圧縮して上記針配置を通して上記第2の薬剤を投薬するように構成される。
Claims (15)
- 薬物送達デバイスとともに使用するための薬用モジュール(100)であって、該薬用モジュール(100)は、
第1の薬剤(110)を含んでなる該薬物送達デバイスへの取り付けのために構成されるハウジング(120);
該ハウジング(120)内に含まれる折り畳みリザーバ(124);
該折り畳みリザーバ(124)内に含まれる所定体積の第2の薬剤(190);
上記ハウジング(120)内に構成され、該折り畳みリザーバ(124)及び上記薬物送達デバイスと流体連通して配置される、針配置(166);及び
該ハウジング(120)内に部分的に構成されるニードルシュラウド(150)を含んでなり:
ここで該ニードルシュラウド(150)は、上記折り畳みリザーバ(124)を圧縮して上記針配置(166)を通して上記第2の薬剤(190)を投薬するように構成される、上記薬用モジュール(100)。 - 投薬中、前記第2の薬剤(190)は、前記薬物送達デバイス内に含まれる前記第1の薬剤(110)の初回投与前に投薬される、請求項1に記載の薬用モジュール(100)。
- 前記薬物送達デバイス内に含まれる前記第1の薬剤(110)の前記初回投与は固定用量を含む、請求項2に記載の薬用モジュール(100)。
- 前記第1の薬剤(110)の前記初回投与は可変用量を含む、請求項2に記載の薬用モジュール(100)。
- 前記折り畳みリザーバ(124)内に含まれる前記第2の薬剤(190)の前記所定体積は上記第2の薬剤(190)の固定用量を含む、請求項1〜4のいずれか1項に記載の薬用モジュール(100)。
- 前記ハウジング(120)は、前記薬物送達デバイスへの恒久的な取り付けのために構成される、請求項1〜5のいずれか1項に記載の薬用モジュール(100)。
- 前記シュラウド(150)は前記ハウジング(120)内で付勢される、請求項1〜6のいずれか1項に記載の薬用モジュール(100)。
- 前記シュラウド(150)はばね(160)により前記ハウジング(120)内で付勢される、請求項7に記載の薬用モジュール(100)。
- 前記シュラウド(150)の部分は、管状形状を含んで該管状形状が前記針配置(166)の部分を実質的に隠す、請求項1〜8のいずれか1項に記載の薬用モジュール(100)。
- 前記針配置(166)は、
前記折り畳みリザーバ(124)と流体連通している第1の針(170)、
及び
前記薬物送達デバイス内に含まれる前記第1の薬剤(110)及び上記折り畳みリザーバ(124)の両方と流体連通している第2の針(180)
を含む、請求項1〜9のいずれか1項に記載の薬用モジュール(100)。 - 請求項1〜9のいずれか1項に記載の薬用モジュール(100)であって:
前記針配置(166)が第1及び第2の薬剤(110、190)の両方と流体連通するように構成される単一の単体針を含み、ここで該単一の単体針は、(i)薬物送達デバイス(102)と流体連通のために構成される近位穿孔端;(ii)注射用に構成される遠位穿孔端;及び(iii)前記折り畳みリザーバ(124)内部に位置する少なくとも1つの側部鋳抜穴を含み、ここで少なくとも1つの穴はニードルシュラウド(150)の後退による折り畳みリザーバ(124)からの薬剤の流れを容易にするように配置される、上記薬用モジュール(100)。 - 少なくとも1つの側部鋳抜穴は折り畳みリザーバ(124)の上部穿孔部材(126)の直下に置かれる、請求項11に記載の薬用モジュール。
- シュラウド(150)の後退により、密閉リザーバ(124)は針に沿ってスライドアップし、薬剤が排出される、請求項11又は請求項12に記載の薬用モジュール。
- 前記第2の薬剤(190)はGLP−1又はGLP−1アナログを含む、請求項1〜13のいずれか1項に記載の薬用モジュール(100)。
- 前記薬物送達デバイスはペン注射器を含む、請求項1〜14のいずれか1項に記載の薬用モジュール(100)。
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
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EP10189797 | 2010-11-03 | ||
EP10189800 | 2010-11-03 | ||
EP10189797.3 | 2010-11-03 | ||
US201161432704P | 2011-01-14 | 2011-01-14 | |
US61/432,704 | 2011-01-14 | ||
PCT/EP2011/069106 WO2012059457A1 (en) | 2010-11-03 | 2011-10-31 | Medicated module for administering fixed dose |
Publications (2)
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JP2013542794A true JP2013542794A (ja) | 2013-11-28 |
JP5968326B2 JP5968326B2 (ja) | 2016-08-10 |
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JP2013537103A Pending JP2013542795A (ja) | 2010-11-03 | 2011-10-31 | 固定用量を投与するための薬用モジュール |
JP2013537102A Expired - Fee Related JP5968326B2 (ja) | 2010-11-03 | 2011-10-31 | 固定用量を投与するための薬用モジュール |
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US (2) | US9180253B2 (ja) |
EP (2) | EP2635325A1 (ja) |
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US11191907B2 (en) | 2016-12-07 | 2021-12-07 | Sanofi-Aventis Deutschland Gmbh | Cap for an injection device |
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JP2013523202A (ja) | 2010-03-25 | 2013-06-17 | ニュー インジェクション システムズ リミテッド | 注射器 |
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RU2655544C2 (ru) | 2012-11-23 | 2018-05-28 | Нью Инджекшн Системз Лтд | Узел автоматического инъектора |
US9125995B2 (en) | 2012-12-05 | 2015-09-08 | Glucago Llc | Reconstitution devices |
CN104968378A (zh) * | 2012-12-19 | 2015-10-07 | 诺和诺德股份有限公司 | 针装置 |
US9889256B2 (en) | 2013-05-03 | 2018-02-13 | Medimop Medical Projects Ltd. | Sensing a status of an infuser based on sensing motor control and power input |
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- 2011-10-31 EP EP11779382.8A patent/EP2635324A1/en not_active Withdrawn
- 2011-10-31 US US13/882,702 patent/US9180253B2/en active Active
- 2011-10-31 WO PCT/EP2011/069106 patent/WO2012059457A1/en active Application Filing
- 2011-10-31 US US13/883,190 patent/US20130226081A1/en not_active Abandoned
- 2011-10-31 WO PCT/EP2011/069107 patent/WO2012059458A1/en active Application Filing
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Also Published As
Publication number | Publication date |
---|---|
EP2635324A1 (en) | 2013-09-11 |
WO2012059457A1 (en) | 2012-05-10 |
US9180253B2 (en) | 2015-11-10 |
US20130218089A1 (en) | 2013-08-22 |
JP2013542795A (ja) | 2013-11-28 |
JP5968326B2 (ja) | 2016-08-10 |
WO2012059458A1 (en) | 2012-05-10 |
US20130226081A1 (en) | 2013-08-29 |
EP2635325A1 (en) | 2013-09-11 |
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