JP2013537205A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2013537205A5 JP2013537205A5 JP2013528537A JP2013528537A JP2013537205A5 JP 2013537205 A5 JP2013537205 A5 JP 2013537205A5 JP 2013528537 A JP2013528537 A JP 2013528537A JP 2013528537 A JP2013528537 A JP 2013528537A JP 2013537205 A5 JP2013537205 A5 JP 2013537205A5
- Authority
- JP
- Japan
- Prior art keywords
- atoms
- independently
- alk
- nyy
- replaced
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 125000004432 carbon atom Chemical group C* 0.000 claims description 35
- 125000000217 alkyl group Chemical group 0.000 claims description 20
- 150000001875 compounds Chemical class 0.000 claims description 20
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 20
- 150000003839 salts Chemical class 0.000 claims 13
- 239000000203 mixture Substances 0.000 claims 9
- 238000002360 preparation method Methods 0.000 claims 9
- 239000012453 solvate Substances 0.000 claims 9
- 125000003118 aryl group Chemical group 0.000 claims 7
- 125000002619 bicyclic group Chemical group 0.000 claims 7
- 125000002950 monocyclic group Chemical group 0.000 claims 7
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims 4
- ISAOCJYIOMOJEB-UHFFFAOYSA-N benzoin Chemical compound C=1C=CC=CC=1C(O)C(=O)C1=CC=CC=C1 ISAOCJYIOMOJEB-UHFFFAOYSA-N 0.000 claims 4
- 238000006243 chemical reaction Methods 0.000 claims 3
- HYBBIBNJHNGZAN-UHFFFAOYSA-N furfural Chemical class O=CC1=CC=CO1 HYBBIBNJHNGZAN-UHFFFAOYSA-N 0.000 claims 3
- QIGBRXMKCJKVMJ-UHFFFAOYSA-N Hydroquinone Chemical compound OC1=CC=C(O)C=C1 QIGBRXMKCJKVMJ-UHFFFAOYSA-N 0.000 claims 2
- 244000028419 Styrax benzoin Species 0.000 claims 2
- 235000000126 Styrax benzoin Nutrition 0.000 claims 2
- 235000008411 Sumatra benzointree Nutrition 0.000 claims 2
- 239000004904 UV filter Substances 0.000 claims 2
- 239000002253 acid Substances 0.000 claims 2
- 239000003963 antioxidant agent Substances 0.000 claims 2
- 235000006708 antioxidants Nutrition 0.000 claims 2
- 229960005070 ascorbic acid Drugs 0.000 claims 2
- 235000010323 ascorbic acid Nutrition 0.000 claims 2
- 239000011668 ascorbic acid Substances 0.000 claims 2
- 229960002130 benzoin Drugs 0.000 claims 2
- 239000000945 filler Substances 0.000 claims 2
- 235000019382 gum benzoic Nutrition 0.000 claims 2
- BJRNKVDFDLYUGJ-RMPHRYRLSA-N hydroquinone O-beta-D-glucopyranoside Chemical class O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=CC=C(O)C=C1 BJRNKVDFDLYUGJ-RMPHRYRLSA-N 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- BDJRBEYXGGNYIS-UHFFFAOYSA-N nonanedioic acid Chemical class OC(=O)CCCCCCCC(O)=O BDJRBEYXGGNYIS-UHFFFAOYSA-N 0.000 claims 2
- 239000000126 substance Substances 0.000 claims 2
- 239000011782 vitamin Substances 0.000 claims 2
- 229940088594 vitamin Drugs 0.000 claims 2
- 235000013343 vitamin Nutrition 0.000 claims 2
- 229930003231 vitamin Natural products 0.000 claims 2
- 230000002087 whitening effect Effects 0.000 claims 2
- HKIKAXXIWJHWLY-ZIIYPAMZSA-N Aloesin Chemical class C=12OC(CC(=O)C)=CC(=O)C2=C(C)C=C(O)C=1[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O HKIKAXXIWJHWLY-ZIIYPAMZSA-N 0.000 claims 1
- HKIKAXXIWJHWLY-QEVGBQTESA-N Aloesin Chemical class O=C(CC=1Oc2c([C@H]3[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O3)c(O)cc(C)c2C(=O)C=1)C HKIKAXXIWJHWLY-QEVGBQTESA-N 0.000 claims 1
- 208000035484 Cellulite Diseases 0.000 claims 1
- 208000001840 Dandruff Diseases 0.000 claims 1
- AFSDNFLWKVMVRB-UHFFFAOYSA-N Ellagic acid Chemical compound OC1=C(O)C(OC2=O)=C3C4=C2C=C(O)C(O)=C4OC(=O)C3=C1 AFSDNFLWKVMVRB-UHFFFAOYSA-N 0.000 claims 1
- ATJXMQHAMYVHRX-CPCISQLKSA-N Ellagic acid Natural products OC1=C(O)[C@H]2OC(=O)c3cc(O)c(O)c4OC(=O)C(=C1)[C@H]2c34 ATJXMQHAMYVHRX-CPCISQLKSA-N 0.000 claims 1
- 229920002079 Ellagic acid Polymers 0.000 claims 1
- 240000000249 Morus alba Species 0.000 claims 1
- 235000008708 Morus alba Nutrition 0.000 claims 1
- DFPAKSUCGFBDDF-UHFFFAOYSA-N Nicotinamide Chemical compound NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 claims 1
- 206010049752 Peau d'orange Diseases 0.000 claims 1
- 208000012641 Pigmentation disease Diseases 0.000 claims 1
- 206010064127 Solar lentigo Diseases 0.000 claims 1
- 102000003425 Tyrosinase Human genes 0.000 claims 1
- 108060008724 Tyrosinase Proteins 0.000 claims 1
- 230000003712 anti-aging effect Effects 0.000 claims 1
- 230000000844 anti-bacterial effect Effects 0.000 claims 1
- 230000003110 anti-inflammatory effect Effects 0.000 claims 1
- 230000001153 anti-wrinkle effect Effects 0.000 claims 1
- 229960000271 arbutin Drugs 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 238000004040 coloring Methods 0.000 claims 1
- 239000002537 cosmetic Substances 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229960002852 ellagic acid Drugs 0.000 claims 1
- 235000004132 ellagic acid Nutrition 0.000 claims 1
- UQPHVQVXLPRNCX-UHFFFAOYSA-N erythrulose Chemical compound OCC(O)C(=O)CO UQPHVQVXLPRNCX-UHFFFAOYSA-N 0.000 claims 1
- 229960004337 hydroquinone Drugs 0.000 claims 1
- 230000005764 inhibitory process Effects 0.000 claims 1
- BEJNERDRQOWKJM-UHFFFAOYSA-N kojic acid Chemical class OCC1=CC(=O)C(O)=CO1 BEJNERDRQOWKJM-UHFFFAOYSA-N 0.000 claims 1
- WZNJWVWKTVETCG-UHFFFAOYSA-N kojic acid Chemical class OC(=O)C(N)CN1C=CC(=O)C(O)=C1 WZNJWVWKTVETCG-UHFFFAOYSA-N 0.000 claims 1
- 229960004705 kojic acid Drugs 0.000 claims 1
- 229940069445 licorice extract Drugs 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- FAARLWTXUUQFSN-UHFFFAOYSA-N methylellagic acid Natural products O1C(=O)C2=CC(O)=C(O)C3=C2C2=C1C(OC)=C(O)C=C2C(=O)O3 FAARLWTXUUQFSN-UHFFFAOYSA-N 0.000 claims 1
- 229960003966 nicotinamide Drugs 0.000 claims 1
- 235000005152 nicotinamide Nutrition 0.000 claims 1
- 239000011570 nicotinamide Substances 0.000 claims 1
- BJRNKVDFDLYUGJ-UHFFFAOYSA-N p-hydroxyphenyl beta-D-alloside Chemical class OC1C(O)C(O)C(CO)OC1OC1=CC=C(O)C=C1 BJRNKVDFDLYUGJ-UHFFFAOYSA-N 0.000 claims 1
- 239000000049 pigment Substances 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 230000000699 topical effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102010045890.2 | 2010-09-17 | ||
| DE102010045890A DE102010045890A1 (de) | 2010-09-17 | 2010-09-17 | 2,2'-Furoin-Derivte und deren Verwendung zur Hautaufhellung |
| PCT/EP2011/004160 WO2012034629A1 (de) | 2010-09-17 | 2011-08-18 | 2,2'-furoin-derivate und deren verwendung zur hautaufhellung |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013537205A JP2013537205A (ja) | 2013-09-30 |
| JP2013537205A5 true JP2013537205A5 (enExample) | 2014-10-02 |
| JP5731653B2 JP5731653B2 (ja) | 2015-06-10 |
Family
ID=44584120
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013528537A Expired - Fee Related JP5731653B2 (ja) | 2010-09-17 | 2011-08-18 | 2,2’−フロイン誘導体および皮膚を明るくするためのその使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US8906351B2 (enExample) |
| EP (1) | EP2616040B1 (enExample) |
| JP (1) | JP5731653B2 (enExample) |
| CN (1) | CN103179948A (enExample) |
| DE (1) | DE102010045890A1 (enExample) |
| WO (1) | WO2012034629A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8654815B1 (en) | 2004-04-02 | 2014-02-18 | Rearden, Llc | System and method for distributed antenna wireless communications |
| US9469626B2 (en) | 2012-07-03 | 2016-10-18 | Colorado State University Research Foundation | Biorefining compounds and organocatalytic upgrading methods |
| DE102013204070A1 (de) * | 2013-03-11 | 2014-09-11 | Beiersdorf Ag | Verwendung kosmetisch oder dermatologisch unbedenklicher substituierter Michael-Akzeptoren zur Verhinderung, Verminderung oder Prophylaxe der Tyrosinaseaktivität der menschlichen Haut und/oder deren Aufhellung |
| CN107759542A (zh) * | 2017-11-13 | 2018-03-06 | 天津工业大学 | 噻唑类离子液体催化糠醛耦合为糠偶姻 |
| TWI839353B (zh) * | 2018-06-28 | 2024-04-21 | 德商漢高股份有限及兩合公司 | 展現低固化溫度之含有潛還原劑的陽離子性可固化組合物 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE242625T1 (de) * | 1990-04-26 | 2003-06-15 | Procter & Gamble | Chelat-zubereitungen, die oximverbindungen enthalten |
| TW197375B (enExample) | 1990-11-19 | 1993-01-01 | Hayashibara Biochem Lab | |
| FR2680683B1 (fr) | 1991-08-29 | 1993-11-12 | Oreal | Composition cosmetique filtrante contenant un polymere filtre a structure hydrocarbonee et une silicone filtre. |
| DE4308282C2 (de) | 1993-03-16 | 1994-12-22 | Beiersdorf Ag | Vorzugsweise in Form von Mikrosphärulen vorliegende galenische Matrices |
| DE4434494A1 (de) | 1994-09-27 | 1996-03-28 | Henkel Kgaa | 2-Hydroxy-1-ethanon-Derivate zum Färben keratinhaltiger Fasern |
| DE19704273A1 (de) | 1996-03-08 | 1997-09-11 | Basf Ag | Verfahren zur katalytischen Herstellung von optisch aktiven Hydroxyketonen |
| DE10133202A1 (de) | 2001-07-07 | 2003-01-16 | Beiersdorf Ag | Osmolyte enthaltende kosmetische und dermatologische Zubereitungen zur Behandlung und aktiven Prävention trockener Haut und anderer negativer Veränderungen der physiologischen Homöostase der gesunden Haut |
| WO2004003198A1 (ja) * | 2002-06-27 | 2004-01-08 | Genox Research, Inc. | アレルギー性疾患の検査方法、および治療のための薬剤 |
| WO2004006878A1 (en) * | 2002-07-10 | 2004-01-22 | Ciba Specialty Chemicals Holding Inc. | Merocyanine derivatives for cosmetic use |
| JP2004155681A (ja) * | 2002-11-05 | 2004-06-03 | Lion Corp | 口腔バイオフィルム抑制剤および口腔用組成物 |
| DE10337863A1 (de) | 2003-08-18 | 2005-03-17 | Merck Patent Gmbh | Verwendung von Chromen-4-on-Derivaten |
| EP1871735B1 (de) | 2005-04-19 | 2015-12-23 | Merck Patent GmbH | Antioxidantien |
| CN101809023A (zh) * | 2007-09-28 | 2010-08-18 | 陶氏康宁公司 | 含有抗坏血酸的酯衍生物的有机基硅氧烷 |
-
2010
- 2010-09-17 DE DE102010045890A patent/DE102010045890A1/de not_active Withdrawn
-
2011
- 2011-08-18 US US13/817,854 patent/US8906351B2/en not_active Expired - Fee Related
- 2011-08-18 JP JP2013528537A patent/JP5731653B2/ja not_active Expired - Fee Related
- 2011-08-18 WO PCT/EP2011/004160 patent/WO2012034629A1/de not_active Ceased
- 2011-08-18 CN CN2011800512377A patent/CN103179948A/zh active Pending
- 2011-08-18 EP EP11752111.2A patent/EP2616040B1/de not_active Not-in-force
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2013537205A5 (enExample) | ||
| CN102227407B (zh) | 丙型肝炎病毒抑制剂 | |
| EP4209494A1 (en) | Ring-modified proline short peptide compound and use thereof | |
| EP2452680B1 (en) | Acid pump antagonist for the treatment of diseases involved in abnormal gastrointestinal motility | |
| EP2787002B1 (en) | Oleanolic acid amidate derivatives, preparation methods and uses thereof | |
| WO2010097480A3 (en) | Menthyl carbamate compounds as skin and/or hair lightening actives | |
| EA201000552A1 (ru) | Производные пирроло[2,3-d]пиримидина в качестве ингибиторов протеинкиназы в | |
| UA80973C2 (uk) | Інгібітори вірусу гепатиту с | |
| MX2009008953A (es) | Compuestos como inhibidores de angiogenesis. | |
| JP2010070503A (ja) | 抗真菌作用2−アミノトリアゾロピリジン誘導体 | |
| WO2016210289A1 (en) | Chemical modulators of signaling pathways and therapeutic use | |
| WO2016210247A1 (en) | New methods of use for an anti-diarrhea agent | |
| NZ596047A (en) | Stabilized lipid formulation of apoptosis promoter | |
| HRP20130959T1 (hr) | Antikancerozni spojevi i farmaceutski pripravci koji ih sadrže | |
| JP2015500885A5 (enExample) | ||
| JP2011516511A5 (enExample) | ||
| CN117956992A (zh) | Menin-mll相互作用的抑制剂 | |
| DK2767538T3 (en) | TETRANDRINDERIVATER with substituted 5-CARBON, PRODUCTION PROCESS AND USE THEREOF | |
| WO2012026813A3 (en) | Analogs of geranylgeranylacetone and uses thereof | |
| SI3174881T1 (en) | (1,2,4) triazolo (4,3-B) pyridazines for use in the treatment of proliferative diseases | |
| WO2009134404A3 (en) | Steroidal compounds as melanogenesis modifiers and uses thereof | |
| EP2616040B1 (de) | 2,2'-furoin-derivate und deren verwendung zur hautaufhellung | |
| MY148903A (en) | Di(hetero)arylclohexane derivatives, their preparation, their use and pharmaceutical compositions comprising them | |
| RU2016114904A (ru) | Новая кристаллическая солевая форма 3-(1,2,4-триазоло[4,3-а]пиридин-3-илэтинил)-4-метил-n-(4-((4-метилпиперазин-1-ил)метил)-3-трифторметилфенил)бензамида для медицинского применения | |
| NZ613333A (en) | Derivatives of glyco-cf2-serine and glyco-cf2-threonine |