JP2013536156A5 - - Google Patents
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- Publication number
- JP2013536156A5 JP2013536156A5 JP2013503918A JP2013503918A JP2013536156A5 JP 2013536156 A5 JP2013536156 A5 JP 2013536156A5 JP 2013503918 A JP2013503918 A JP 2013503918A JP 2013503918 A JP2013503918 A JP 2013503918A JP 2013536156 A5 JP2013536156 A5 JP 2013536156A5
- Authority
- JP
- Japan
- Prior art keywords
- lipoic acid
- wound dressing
- acid derivative
- scaffold
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 206010052428 Wound Diseases 0.000 claims 32
- 208000027418 Wounds and injury Diseases 0.000 claims 32
- AGBQKNBQESQNJD-UHFFFAOYSA-N lipoic acid Chemical class OC(=O)CCCCC1CCSS1 AGBQKNBQESQNJD-UHFFFAOYSA-N 0.000 claims 32
- 239000000758 substrate Substances 0.000 claims 23
- 238000000034 method Methods 0.000 claims 18
- 239000000203 mixture Substances 0.000 claims 17
- 125000000008 (C1-C10) alkyl group Chemical group 0.000 claims 15
- 102000035195 Peptidases Human genes 0.000 claims 13
- 108091005804 Peptidases Proteins 0.000 claims 13
- 239000000463 material Substances 0.000 claims 10
- 125000005915 C6-C14 aryl group Chemical group 0.000 claims 9
- 235000019136 lipoic acid Nutrition 0.000 claims 7
- 229920002635 polyurethane Polymers 0.000 claims 7
- 239000004814 polyurethane Substances 0.000 claims 7
- 229960002663 thioctic acid Drugs 0.000 claims 7
- 125000005210 alkyl ammonium group Chemical group 0.000 claims 6
- 150000001413 amino acids Chemical class 0.000 claims 6
- 239000002738 chelating agent Substances 0.000 claims 5
- 230000001419 dependent effect Effects 0.000 claims 5
- 102000008186 Collagen Human genes 0.000 claims 4
- 108010035532 Collagen Proteins 0.000 claims 4
- 108010010803 Gelatin Proteins 0.000 claims 4
- 229920001436 collagen Polymers 0.000 claims 4
- 239000006260 foam Substances 0.000 claims 4
- 229920000159 gelatin Polymers 0.000 claims 4
- 239000008273 gelatin Substances 0.000 claims 4
- 235000019322 gelatine Nutrition 0.000 claims 4
- 235000011852 gelatine desserts Nutrition 0.000 claims 4
- IZFHEQBZOYJLPK-SSDOTTSWSA-N (R)-dihydrolipoic acid Chemical compound OC(=O)CCCC[C@@H](S)CCS IZFHEQBZOYJLPK-SSDOTTSWSA-N 0.000 claims 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims 3
- 239000003242 anti bacterial agent Substances 0.000 claims 3
- 238000001035 drying Methods 0.000 claims 3
- 239000012530 fluid Substances 0.000 claims 3
- 239000003102 growth factor Substances 0.000 claims 3
- 239000000137 peptide hydrolase inhibitor Substances 0.000 claims 3
- 239000003755 preservative agent Substances 0.000 claims 3
- 230000002335 preservative effect Effects 0.000 claims 3
- 235000018102 proteins Nutrition 0.000 claims 3
- 102000004169 proteins and genes Human genes 0.000 claims 3
- 108090000623 proteins and genes Proteins 0.000 claims 3
- 150000003839 salts Chemical class 0.000 claims 3
- AGBQKNBQESQNJD-SSDOTTSWSA-N (R)-lipoic acid Chemical group OC(=O)CCCC[C@@H]1CCSS1 AGBQKNBQESQNJD-SSDOTTSWSA-N 0.000 claims 2
- VAZJLPXFVQHDFB-UHFFFAOYSA-N 1-(diaminomethylidene)-2-hexylguanidine Polymers CCCCCCN=C(N)N=C(N)N VAZJLPXFVQHDFB-UHFFFAOYSA-N 0.000 claims 2
- GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical compound C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 claims 2
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical group OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 claims 2
- 229920002413 Polyhexanide Polymers 0.000 claims 2
- XEFQLINVKFYRCS-UHFFFAOYSA-N Triclosan Chemical compound OC1=CC(Cl)=CC=C1OC1=CC=C(Cl)C=C1Cl XEFQLINVKFYRCS-UHFFFAOYSA-N 0.000 claims 2
- 239000004599 antimicrobial Substances 0.000 claims 2
- 229960000686 benzalkonium chloride Drugs 0.000 claims 2
- CADWTSSKOVRVJC-UHFFFAOYSA-N benzyl(dimethyl)azanium;chloride Chemical compound [Cl-].C[NH+](C)CC1=CC=CC=C1 CADWTSSKOVRVJC-UHFFFAOYSA-N 0.000 claims 2
- 229960003260 chlorhexidine Drugs 0.000 claims 2
- 230000002757 inflammatory effect Effects 0.000 claims 2
- 239000011148 porous material Substances 0.000 claims 2
- 229910052709 silver Inorganic materials 0.000 claims 2
- 239000004332 silver Substances 0.000 claims 2
- 229960003500 triclosan Drugs 0.000 claims 2
- 230000029663 wound healing Effects 0.000 claims 2
- 102000009027 Albumins Human genes 0.000 claims 1
- 108010088751 Albumins Proteins 0.000 claims 1
- 102000011632 Caseins Human genes 0.000 claims 1
- 108010076119 Caseins Proteins 0.000 claims 1
- 102000016942 Elastin Human genes 0.000 claims 1
- 108010014258 Elastin Proteins 0.000 claims 1
- 102000004190 Enzymes Human genes 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- 108010049003 Fibrinogen Proteins 0.000 claims 1
- 102000008946 Fibrinogen Human genes 0.000 claims 1
- 102000016359 Fibronectins Human genes 0.000 claims 1
- 108010067306 Fibronectins Proteins 0.000 claims 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims 1
- 108010076876 Keratins Proteins 0.000 claims 1
- 102000011782 Keratins Human genes 0.000 claims 1
- 102000014171 Milk Proteins Human genes 0.000 claims 1
- 108010011756 Milk Proteins Proteins 0.000 claims 1
- 108010073771 Soybean Proteins Proteins 0.000 claims 1
- 241000209140 Triticum Species 0.000 claims 1
- 235000021307 Triticum Nutrition 0.000 claims 1
- 240000008042 Zea mays Species 0.000 claims 1
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 claims 1
- 235000002017 Zea mays subsp mays Nutrition 0.000 claims 1
- 239000000853 adhesive Substances 0.000 claims 1
- 230000001070 adhesive effect Effects 0.000 claims 1
- 210000001124 body fluid Anatomy 0.000 claims 1
- 239000010839 body fluid Substances 0.000 claims 1
- 239000005018 casein Substances 0.000 claims 1
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 claims 1
- 235000021240 caseins Nutrition 0.000 claims 1
- 230000015556 catabolic process Effects 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 235000005822 corn Nutrition 0.000 claims 1
- 230000006837 decompression Effects 0.000 claims 1
- 238000006731 degradation reaction Methods 0.000 claims 1
- 229920002549 elastin Polymers 0.000 claims 1
- 229940012952 fibrinogen Drugs 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 238000003825 pressing Methods 0.000 claims 1
- 229910052708 sodium Inorganic materials 0.000 claims 1
- 239000011734 sodium Substances 0.000 claims 1
- 159000000000 sodium salts Chemical class 0.000 claims 1
- 229940001941 soy protein Drugs 0.000 claims 1
- 230000001954 sterilising effect Effects 0.000 claims 1
- 238000002560 therapeutic procedure Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12/757,562 US8632512B2 (en) | 2010-04-09 | 2010-04-09 | Apparatuses, methods, and compositions for the treatment and prophylaxis of chronic wounds |
| US12/757,562 | 2010-04-09 | ||
| PCT/US2011/031441 WO2011127188A2 (en) | 2010-04-09 | 2011-04-06 | Apparatuses, methods, and compositions for the treatment and prophylaxis of chronic wounds |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016085736A Division JP6189473B2 (ja) | 2010-04-09 | 2016-04-22 | 慢性創傷を治療及び予防するための装置、方法、及び組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013536156A JP2013536156A (ja) | 2013-09-19 |
| JP2013536156A5 true JP2013536156A5 (enExample) | 2014-05-22 |
| JP5988309B2 JP5988309B2 (ja) | 2016-09-07 |
Family
ID=44059227
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013503918A Active JP5988309B2 (ja) | 2010-04-09 | 2011-04-06 | 慢性創傷を治療及び予防するための装置、方法、及び組成物 |
| JP2016085736A Expired - Fee Related JP6189473B2 (ja) | 2010-04-09 | 2016-04-22 | 慢性創傷を治療及び予防するための装置、方法、及び組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016085736A Expired - Fee Related JP6189473B2 (ja) | 2010-04-09 | 2016-04-22 | 慢性創傷を治療及び予防するための装置、方法、及び組成物 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US8632512B2 (enExample) |
| EP (1) | EP2555805B1 (enExample) |
| JP (2) | JP5988309B2 (enExample) |
| CN (2) | CN105126156A (enExample) |
| AU (1) | AU2011237638B2 (enExample) |
| CA (1) | CA2790559A1 (enExample) |
| TW (1) | TW201141548A (enExample) |
| WO (1) | WO2011127188A2 (enExample) |
Families Citing this family (68)
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| US11298453B2 (en) | 2003-10-28 | 2022-04-12 | Smith & Nephew Plc | Apparatus and method for wound cleansing with actives |
| GB0808376D0 (en) | 2008-05-08 | 2008-06-18 | Bristol Myers Squibb Co | Wound dressing |
| GB0817796D0 (en) | 2008-09-29 | 2008-11-05 | Convatec Inc | wound dressing |
| US20110212158A1 (en) | 2010-02-18 | 2011-09-01 | Samson Tom | Immunocompatible chorionic membrane products |
| GB201020236D0 (en) | 2010-11-30 | 2011-01-12 | Convatec Technologies Inc | A composition for detecting biofilms on viable tissues |
| US10207031B2 (en) | 2010-12-08 | 2019-02-19 | Convatec Technologies Inc. | Integrated system for assessing wound exudates |
| EP2648794B1 (en) | 2010-12-08 | 2019-08-28 | ConvaTec Technologies Inc. | Wound exudate system accessory |
| DK2648795T3 (da) | 2010-12-08 | 2023-03-27 | Convatec Technologies Inc | System til fjernelse af eksudater fra en sårposition |
| US8597264B2 (en) | 2011-03-24 | 2013-12-03 | Kci Licensing, Inc. | Apparatuses, methods, and compositions for the treatment and prophylaxis of chronic wounds |
| WO2012166784A1 (en) | 2011-05-31 | 2012-12-06 | Lifecell Corporation | Adipose tissue matrices |
| GB201115182D0 (en) | 2011-09-02 | 2011-10-19 | Trio Healthcare Ltd | Skin contact material |
| GB201117296D0 (en) | 2011-10-07 | 2011-11-16 | Neotherix Ltd | Sampling device |
| CN102492109A (zh) * | 2011-11-28 | 2012-06-13 | 西安科技大学 | 一种可生物降解高回弹软质聚氨酯泡沫塑料及其制备方法 |
| GB2497406A (en) | 2011-11-29 | 2013-06-12 | Webtec Converting Llc | Dressing with a perforated binder layer |
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| US10792337B2 (en) | 2013-03-15 | 2020-10-06 | Kci Licensing, Inc. | Wound healing compositions |
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| JP2015105249A (ja) * | 2013-11-29 | 2015-06-08 | 富士フイルム株式会社 | 化粧料 |
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| WO2017173069A1 (en) | 2016-03-30 | 2017-10-05 | Convatec Technologies Inc. | Detecting microbial infections in wounds |
| KR20190008199A (ko) | 2016-03-30 | 2019-01-23 | 시노보 게엠베하 | 상처에서 미생물 감염의 검출 방법 |
| GB201608099D0 (en) | 2016-05-09 | 2016-06-22 | Convatec Technologies Inc | Negative pressure wound dressing |
| CA3029579A1 (en) | 2016-07-05 | 2018-01-11 | Lifecell Corporation | Tissue matrices incorporating multiple tissue types |
| MX2019000232A (es) | 2016-07-08 | 2019-11-12 | Convatec Technologies Inc | Deteccion de flujo de fluidos. |
| BR112019000284A2 (pt) | 2016-07-08 | 2019-04-16 | Convatec Technologies Inc. | aparelho de coleta de fluido |
| CA3030152A1 (en) | 2016-07-08 | 2018-01-11 | Convatec Technologies Inc. | Flexible negative pressure system |
| CN107789660A (zh) * | 2016-08-31 | 2018-03-13 | 杜建 | 一种用于皮肤及软组织损伤的医用敷料 |
| US20200038248A1 (en) * | 2016-10-05 | 2020-02-06 | Temple University- Of The Commonwealth System Of Higher Education | Negative Pressure Enhanced Cellular Infiltration |
| US11471584B2 (en) | 2017-06-07 | 2022-10-18 | Kci Licensing, Inc. | Composite dressings for improved granulation and reduced maceration with negative-pressure treatment |
| WO2018226650A1 (en) | 2017-06-07 | 2018-12-13 | Kci Licensing, Inc. | Systems, apparatuses, and methods for negative-pressure treatment with reduced tissue in-growth |
| CA3066093A1 (en) | 2017-06-07 | 2018-12-13 | Kci Licensing, Inc. | Composite dressings for improved granulation and reduced maceration with negative-pressure treatment |
| WO2018226630A1 (en) * | 2017-06-07 | 2018-12-13 | Kci Licensing, Inc. | Assembly features and methods for a peel-and-place dressing for use with negative-pressure treatment |
| AU2018280130A1 (en) | 2017-06-07 | 2019-12-19 | 3M Innovative Properties Company | Composite dressings for improved granulation reduced maceration with negative-pressure treatment |
| US11207217B2 (en) | 2017-06-07 | 2021-12-28 | Kci Licensing, Inc. | Methods for manufacturing and assembling dual material tissue interface for negative-pressure therapy |
| CA3060588A1 (en) | 2017-06-07 | 2018-12-13 | Kci Licensing, Inc. | Composite dressings for improved granulation and reduced maceration with negative-pressure treatment |
| EP3697460A1 (en) | 2017-10-18 | 2020-08-26 | LifeCell Corporation | Adipose tissue products and methods of production |
| US11123375B2 (en) | 2017-10-18 | 2021-09-21 | Lifecell Corporation | Methods of treating tissue voids following removal of implantable infusion ports using adipose tissue products |
| US11246994B2 (en) | 2017-10-19 | 2022-02-15 | Lifecell Corporation | Methods for introduction of flowable acellular tissue matrix products into a hand |
| CA3075106A1 (en) | 2017-10-19 | 2019-04-25 | Lifecell Corporation | Flowable acellular tissue matrix products and methods of production |
| WO2019089266A1 (en) | 2017-11-03 | 2019-05-09 | Kci Licensing, Inc. | Extended wear-time dressing |
| EP3710074B1 (en) | 2017-11-16 | 2024-03-20 | ConvaTec Limited | Fluid collection apparatus |
| US11752039B2 (en) * | 2018-08-28 | 2023-09-12 | Systagenix Wound Management, Limited | Dressings for reduced tissue ingrowth |
| JP7551652B2 (ja) | 2019-05-08 | 2024-09-17 | マスキュロスケレタル トランスプラント ファウンデーション | 組織由来多孔質マトリックス並びにその作製及び使用方法 |
| CA3142151A1 (en) | 2019-05-30 | 2020-12-03 | Lifecell Corporation | Biologic breast implant |
| WO2020245656A1 (en) | 2019-06-03 | 2020-12-10 | Convatec Limited | Methods and devices to disrupt and contain pathogens |
| CN114126557A (zh) * | 2019-06-26 | 2022-03-01 | 凯希特许有限公司 | 采用用于防止浸渍的特征部的敷料 |
| WO2021028773A1 (en) * | 2019-08-09 | 2021-02-18 | Kci Licensing, Inc. | Negative-pressure system incorporating wound diagnostic capabilities |
| US11331221B2 (en) | 2019-12-27 | 2022-05-17 | Convatec Limited | Negative pressure wound dressing |
| US11771819B2 (en) | 2019-12-27 | 2023-10-03 | Convatec Limited | Low profile filter devices suitable for use in negative pressure wound therapy systems |
| US12152174B2 (en) | 2023-04-13 | 2024-11-26 | The Regents Of The University Of California | Adjustably stable adhesive compositions for medical and non-medical uses, and recycling |
| US12269925B1 (en) | 2024-08-13 | 2025-04-08 | The Regents Of The University Of California | Fast curing, biocompatible and biodegradable adhesives and sealants |
| CN119587755A (zh) * | 2024-12-10 | 2025-03-11 | 重庆大学 | 一种含有载药acc纳米颗粒的双网络水凝胶及其制备方法和应用 |
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-
2010
- 2010-04-09 US US12/757,562 patent/US8632512B2/en active Active
-
2011
- 2011-04-06 EP EP11715141.5A patent/EP2555805B1/en active Active
- 2011-04-06 JP JP2013503918A patent/JP5988309B2/ja active Active
- 2011-04-06 WO PCT/US2011/031441 patent/WO2011127188A2/en not_active Ceased
- 2011-04-06 CN CN201510354734.4A patent/CN105126156A/zh active Pending
- 2011-04-06 AU AU2011237638A patent/AU2011237638B2/en not_active Ceased
- 2011-04-06 CN CN201180015381.5A patent/CN103402556B/zh active Active
- 2011-04-06 CA CA2790559A patent/CA2790559A1/en not_active Abandoned
- 2011-04-08 TW TW100112283A patent/TW201141548A/zh unknown
-
2016
- 2016-04-22 JP JP2016085736A patent/JP6189473B2/ja not_active Expired - Fee Related
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