JP2013533232A5 - - Google Patents
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- JP2013533232A5 JP2013533232A5 JP2013514194A JP2013514194A JP2013533232A5 JP 2013533232 A5 JP2013533232 A5 JP 2013533232A5 JP 2013514194 A JP2013514194 A JP 2013514194A JP 2013514194 A JP2013514194 A JP 2013514194A JP 2013533232 A5 JP2013533232 A5 JP 2013533232A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- cancer
- composition according
- agent
- taxane
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000003795 chemical substances by application Substances 0.000 claims 11
- 206010028980 Neoplasm Diseases 0.000 claims 10
- 201000011510 cancer Diseases 0.000 claims 10
- 229940123237 Taxane Drugs 0.000 claims 8
- DKPFODGZWDEEBT-QFIAKTPHSA-N taxane Chemical class C([C@]1(C)CCC[C@@H](C)[C@H]1C1)C[C@H]2[C@H](C)CC[C@@H]1C2(C)C DKPFODGZWDEEBT-QFIAKTPHSA-N 0.000 claims 8
- 239000002105 nanoparticle Substances 0.000 claims 7
- 102000009027 Albumins Human genes 0.000 claims 5
- 108010088751 Albumins Proteins 0.000 claims 5
- 102000014914 Carrier Proteins Human genes 0.000 claims 5
- 108010078791 Carrier Proteins Proteins 0.000 claims 5
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 claims 3
- 101001012157 Homo sapiens Receptor tyrosine-protein kinase erbB-2 Proteins 0.000 claims 2
- 102000008100 Human Serum Albumin Human genes 0.000 claims 2
- 108091006905 Human Serum Albumin Proteins 0.000 claims 2
- 102100030086 Receptor tyrosine-protein kinase erbB-2 Human genes 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 239000003112 inhibitor Substances 0.000 claims 2
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 claims 2
- 230000002062 proliferating effect Effects 0.000 claims 2
- XAUDJQYHKZQPEU-KVQBGUIXSA-N 5-aza-2'-deoxycytidine Chemical group O=C1N=C(N)N=CN1[C@@H]1O[C@H](CO)[C@@H](O)C1 XAUDJQYHKZQPEU-KVQBGUIXSA-N 0.000 claims 1
- NMUSYJAQQFHJEW-KVTDHHQDSA-N 5-azacytidine Chemical group O=C1N=C(N)N=CN1[C@H]1[C@H](O)[C@H](O)[C@@H](CO)O1 NMUSYJAQQFHJEW-KVTDHHQDSA-N 0.000 claims 1
- 206010005003 Bladder cancer Diseases 0.000 claims 1
- 206010006187 Breast cancer Diseases 0.000 claims 1
- 208000026310 Breast neoplasm Diseases 0.000 claims 1
- 206010008342 Cervix carcinoma Diseases 0.000 claims 1
- 206010014733 Endometrial cancer Diseases 0.000 claims 1
- 206010014759 Endometrial neoplasm Diseases 0.000 claims 1
- 102000003964 Histone deacetylase Human genes 0.000 claims 1
- 108090000353 Histone deacetylase Proteins 0.000 claims 1
- 102000016397 Methyltransferase Human genes 0.000 claims 1
- 108060004795 Methyltransferase Proteins 0.000 claims 1
- 206010033128 Ovarian cancer Diseases 0.000 claims 1
- 206010061535 Ovarian neoplasm Diseases 0.000 claims 1
- 229930012538 Paclitaxel Natural products 0.000 claims 1
- 206010061902 Pancreatic neoplasm Diseases 0.000 claims 1
- 208000007097 Urinary Bladder Neoplasms Diseases 0.000 claims 1
- 208000006105 Uterine Cervical Neoplasms Diseases 0.000 claims 1
- 229960002756 azacitidine Drugs 0.000 claims 1
- 201000010881 cervical cancer Diseases 0.000 claims 1
- 229960003603 decitabine Drugs 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 201000010536 head and neck cancer Diseases 0.000 claims 1
- 208000014829 head and neck neoplasm Diseases 0.000 claims 1
- 208000015486 malignant pancreatic neoplasm Diseases 0.000 claims 1
- 201000001441 melanoma Diseases 0.000 claims 1
- 208000002154 non-small cell lung carcinoma Diseases 0.000 claims 1
- 229960001592 paclitaxel Drugs 0.000 claims 1
- 201000002528 pancreatic cancer Diseases 0.000 claims 1
- 208000008443 pancreatic carcinoma Diseases 0.000 claims 1
- 229910052697 platinum Inorganic materials 0.000 claims 1
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 claims 1
- 208000029729 tumor suppressor gene on chromosome 11 Diseases 0.000 claims 1
- 201000005112 urinary bladder cancer Diseases 0.000 claims 1
- WAEXFXRVDQXREF-UHFFFAOYSA-N vorinostat Chemical group ONC(=O)CCCCCCC(=O)NC1=CC=CC=C1 WAEXFXRVDQXREF-UHFFFAOYSA-N 0.000 claims 1
- 229960000237 vorinostat Drugs 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35233310P | 2010-06-07 | 2010-06-07 | |
| US61/352,333 | 2010-06-07 | ||
| US201161446909P | 2011-02-25 | 2011-02-25 | |
| US61/446,909 | 2011-02-25 | ||
| PCT/US2011/037450 WO2011156119A1 (en) | 2010-06-07 | 2011-05-20 | Combination therapy methods for treating proliferative diseases |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016132221A Division JP2016175947A (ja) | 2010-06-07 | 2016-07-04 | 増殖性疾患を処置するための組み合わせ療法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013533232A JP2013533232A (ja) | 2013-08-22 |
| JP2013533232A5 true JP2013533232A5 (enExample) | 2014-07-03 |
| JP6031437B2 JP6031437B2 (ja) | 2016-11-24 |
Family
ID=45098373
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013514194A Active JP6031437B2 (ja) | 2010-06-07 | 2011-05-20 | 増殖性疾患を処置するための組み合わせ療法 |
| JP2016132221A Withdrawn JP2016175947A (ja) | 2010-06-07 | 2016-07-04 | 増殖性疾患を処置するための組み合わせ療法 |
| JP2018025928A Pending JP2018087227A (ja) | 2010-06-07 | 2018-02-16 | 増殖性疾患を処置するための組み合わせ療法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016132221A Withdrawn JP2016175947A (ja) | 2010-06-07 | 2016-07-04 | 増殖性疾患を処置するための組み合わせ療法 |
| JP2018025928A Pending JP2018087227A (ja) | 2010-06-07 | 2018-02-16 | 増殖性疾患を処置するための組み合わせ療法 |
Country Status (20)
| Country | Link |
|---|---|
| US (4) | US20140155344A1 (enExample) |
| EP (2) | EP2575774A4 (enExample) |
| JP (3) | JP6031437B2 (enExample) |
| KR (1) | KR101850566B1 (enExample) |
| CN (2) | CN105832703A (enExample) |
| AU (2) | AU2011264590B2 (enExample) |
| BR (1) | BR112012031163A2 (enExample) |
| CA (1) | CA2801891C (enExample) |
| CO (1) | CO6670568A2 (enExample) |
| CR (1) | CR20120638A (enExample) |
| IL (2) | IL223190A0 (enExample) |
| MX (1) | MX2012014231A (enExample) |
| MY (1) | MY166014A (enExample) |
| NI (1) | NI201200181A (enExample) |
| NZ (1) | NZ707377A (enExample) |
| PH (1) | PH12012502399A1 (enExample) |
| RU (2) | RU2016103126A (enExample) |
| SG (2) | SG185798A1 (enExample) |
| WO (1) | WO2011156119A1 (enExample) |
| ZA (1) | ZA201208820B (enExample) |
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| US8853260B2 (en) | 1997-06-27 | 2014-10-07 | Abraxis Bioscience, Llc | Formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof |
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| TR200801337T1 (tr) | 2005-08-31 | 2008-07-21 | Abraxis Bioscience, Llc. | Suda zayıf çözülebilen farmasötik ajanlar ve antimikrobiyal ajanlar içeren kompozisyonlar. |
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| MX2012014231A (es) * | 2010-06-07 | 2013-01-28 | Abraxis Bioscience Llc | Metodos de terapia combinada para tratar enfermedades proliferativas. |
| US9149455B2 (en) * | 2012-11-09 | 2015-10-06 | Abraxis Bioscience, Llc | Methods of treating melanoma |
| US9511046B2 (en) * | 2013-01-11 | 2016-12-06 | Abraxis Bioscience, Llc | Methods of treating pancreatic cancer |
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2011
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- 2011-05-20 CN CN201610059985.4A patent/CN105832703A/zh active Pending
- 2011-05-20 CA CA2801891A patent/CA2801891C/en active Active
- 2011-05-20 SG SG2012088001A patent/SG185798A1/en unknown
- 2011-05-20 EP EP11792867.1A patent/EP2575774A4/en not_active Withdrawn
- 2011-05-20 WO PCT/US2011/037450 patent/WO2011156119A1/en not_active Ceased
- 2011-05-20 RU RU2016103126A patent/RU2016103126A/ru not_active Application Discontinuation
- 2011-05-20 PH PH1/2012/502399A patent/PH12012502399A1/en unknown
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