JP2010209081A5 - - Google Patents
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- JP2010209081A5 JP2010209081A5 JP2010088515A JP2010088515A JP2010209081A5 JP 2010209081 A5 JP2010209081 A5 JP 2010209081A5 JP 2010088515 A JP2010088515 A JP 2010088515A JP 2010088515 A JP2010088515 A JP 2010088515A JP 2010209081 A5 JP2010209081 A5 JP 2010209081A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- erbb2
- antibody
- medicament
- article
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 201000011510 cancer Diseases 0.000 claims description 8
- 206010028980 Neoplasm Diseases 0.000 claims description 7
- 206010061818 Disease progression Diseases 0.000 claims description 2
- 239000003814 drug Substances 0.000 claims 12
- 238000004519 manufacturing process Methods 0.000 claims 6
- 239000002246 antineoplastic agent Substances 0.000 claims 4
- 229940127089 cytotoxic agent Drugs 0.000 claims 4
- 206010006187 Breast cancer Diseases 0.000 claims 3
- 208000026310 Breast neoplasm Diseases 0.000 claims 3
- 102100030086 Receptor tyrosine-protein kinase erbB-2 Human genes 0.000 claims 3
- 101710100968 Receptor tyrosine-protein kinase erbB-2 Proteins 0.000 claims 3
- 229940045799 anthracyclines and related substance Drugs 0.000 claims 3
- 201000010099 disease Diseases 0.000 claims 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 3
- 206010009944 Colon cancer Diseases 0.000 claims 2
- 206010073071 hepatocellular carcinoma Diseases 0.000 claims 2
- 230000002018 overexpression Effects 0.000 claims 2
- 206010005003 Bladder cancer Diseases 0.000 claims 1
- 206010055113 Breast cancer metastatic Diseases 0.000 claims 1
- 208000010667 Carcinoma of liver and intrahepatic biliary tract Diseases 0.000 claims 1
- 206010008342 Cervix carcinoma Diseases 0.000 claims 1
- 208000001333 Colorectal Neoplasms Diseases 0.000 claims 1
- 206010014733 Endometrial cancer Diseases 0.000 claims 1
- 206010014759 Endometrial neoplasm Diseases 0.000 claims 1
- 206010017993 Gastrointestinal neoplasms Diseases 0.000 claims 1
- 206010073069 Hepatic cancer Diseases 0.000 claims 1
- 208000008839 Kidney Neoplasms Diseases 0.000 claims 1
- ZDZOTLJHXYCWBA-VCVYQWHSSA-N N-debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol Chemical compound O([C@H]1[C@H]2[C@@](C([C@H](O)C3=C(C)[C@@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C=4C=CC=CC=4)C[C@]1(O)C3(C)C)=O)(C)[C@@H](O)C[C@H]1OC[C@]12OC(=O)C)C(=O)C1=CC=CC=C1 ZDZOTLJHXYCWBA-VCVYQWHSSA-N 0.000 claims 1
- 206010033128 Ovarian cancer Diseases 0.000 claims 1
- 206010061535 Ovarian neoplasm Diseases 0.000 claims 1
- 229930012538 Paclitaxel Natural products 0.000 claims 1
- 206010061902 Pancreatic neoplasm Diseases 0.000 claims 1
- 206010060862 Prostate cancer Diseases 0.000 claims 1
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims 1
- 206010038389 Renal cancer Diseases 0.000 claims 1
- 208000004337 Salivary Gland Neoplasms Diseases 0.000 claims 1
- 206010061934 Salivary gland cancer Diseases 0.000 claims 1
- 206010041067 Small cell lung cancer Diseases 0.000 claims 1
- 208000024770 Thyroid neoplasm Diseases 0.000 claims 1
- 208000007097 Urinary Bladder Neoplasms Diseases 0.000 claims 1
- 208000006105 Uterine Cervical Neoplasms Diseases 0.000 claims 1
- 206010047741 Vulval cancer Diseases 0.000 claims 1
- 208000004354 Vulvar Neoplasms Diseases 0.000 claims 1
- 201000010881 cervical cancer Diseases 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 208000029742 colonic neoplasm Diseases 0.000 claims 1
- 229960003668 docetaxel Drugs 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 208000005017 glioblastoma Diseases 0.000 claims 1
- 201000010536 head and neck cancer Diseases 0.000 claims 1
- 208000014829 head and neck neoplasm Diseases 0.000 claims 1
- 231100000844 hepatocellular carcinoma Toxicity 0.000 claims 1
- 201000010982 kidney cancer Diseases 0.000 claims 1
- 201000007270 liver cancer Diseases 0.000 claims 1
- 201000002250 liver carcinoma Diseases 0.000 claims 1
- 208000014018 liver neoplasm Diseases 0.000 claims 1
- 208000015486 malignant pancreatic neoplasm Diseases 0.000 claims 1
- 208000002154 non-small cell lung carcinoma Diseases 0.000 claims 1
- 229960001592 paclitaxel Drugs 0.000 claims 1
- 201000002528 pancreatic cancer Diseases 0.000 claims 1
- 208000008443 pancreatic carcinoma Diseases 0.000 claims 1
- 102000005962 receptors Human genes 0.000 claims 1
- 108020003175 receptors Proteins 0.000 claims 1
- 208000000587 small cell lung carcinoma Diseases 0.000 claims 1
- 206010041823 squamous cell carcinoma Diseases 0.000 claims 1
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 claims 1
- 201000002510 thyroid cancer Diseases 0.000 claims 1
- 208000029729 tumor suppressor gene on chromosome 11 Diseases 0.000 claims 1
- 201000005112 urinary bladder cancer Diseases 0.000 claims 1
- 201000005102 vulva cancer Diseases 0.000 claims 1
- 230000003902 lesion Effects 0.000 description 8
- 206010061309 Neoplasm progression Diseases 0.000 description 1
- 230000001640 apoptogenic effect Effects 0.000 description 1
- 238000001574 biopsy Methods 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 230000030833 cell death Effects 0.000 description 1
- 230000034994 death Effects 0.000 description 1
- 230000005750 disease progression Effects 0.000 description 1
- 230000009422 growth inhibiting effect Effects 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000007619 statistical method Methods 0.000 description 1
- 210000000779 thoracic wall Anatomy 0.000 description 1
- 210000004881 tumor cell Anatomy 0.000 description 1
- 230000005751 tumor progression Effects 0.000 description 1
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6934697P | 1997-12-12 | 1997-12-12 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000539062A Division JP2002508397A (ja) | 1997-12-12 | 1998-12-10 | 抗ＥｒｂＢ２抗体を用いた治療方法 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012222108A Division JP2013056887A (ja) | 1997-12-12 | 2012-10-04 | 抗ＥｒｂＢ２抗体を用いた治療方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010209081A JP2010209081A (ja) | 2010-09-24 |
| JP2010209081A5 true JP2010209081A5 (enExample) | 2011-10-06 |
Family
ID=22088358
Family Applications (7)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000539062A Withdrawn JP2002508397A (ja) | 1997-12-12 | 1998-12-10 | 抗ＥｒｂＢ２抗体を用いた治療方法 |
| JP2010088515A Pending JP2010209081A (ja) | 1997-12-12 | 2010-04-07 | 抗ＥｒｂＢ２抗体を用いた治療方法 |
| JP2012222108A Withdrawn JP2013056887A (ja) | 1997-12-12 | 2012-10-04 | 抗ＥｒｂＢ２抗体を用いた治療方法 |
| JP2015116874A Withdrawn JP2016006046A (ja) | 1997-12-12 | 2015-06-09 | 抗ＥｒｂＢ２抗体を用いた治療方法 |
| JP2016185281A Pending JP2017039737A (ja) | 1997-12-12 | 2016-09-23 | 抗ＥｒｂＢ２抗体を用いた治療方法 |
| JP2017075241A Withdrawn JP2017165737A (ja) | 1997-12-12 | 2017-04-05 | 抗ＥｒｂＢ２抗体を用いた治療方法 |
| JP2018227941A Pending JP2019055979A (ja) | 1997-12-12 | 2018-12-05 | 抗ＥｒｂＢ２抗体を用いた治療方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000539062A Withdrawn JP2002508397A (ja) | 1997-12-12 | 1998-12-10 | 抗ＥｒｂＢ２抗体を用いた治療方法 |
Family Applications After (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012222108A Withdrawn JP2013056887A (ja) | 1997-12-12 | 2012-10-04 | 抗ＥｒｂＢ２抗体を用いた治療方法 |
| JP2015116874A Withdrawn JP2016006046A (ja) | 1997-12-12 | 2015-06-09 | 抗ＥｒｂＢ２抗体を用いた治療方法 |
| JP2016185281A Pending JP2017039737A (ja) | 1997-12-12 | 2016-09-23 | 抗ＥｒｂＢ２抗体を用いた治療方法 |
| JP2017075241A Withdrawn JP2017165737A (ja) | 1997-12-12 | 2017-04-05 | 抗ＥｒｂＢ２抗体を用いた治療方法 |
| JP2018227941A Pending JP2019055979A (ja) | 1997-12-12 | 2018-12-05 | 抗ＥｒｂＢ２抗体を用いた治療方法 |
Country Status (17)
| Country | Link |
|---|---|
| US (11) | US7846441B1 (enExample) |
| EP (3) | EP2277919A1 (enExample) |
| JP (7) | JP2002508397A (enExample) |
| KR (7) | KR20010033019A (enExample) |
| CN (2) | CN1820734B (enExample) |
| AR (1) | AR020051A1 (enExample) |
| AU (1) | AU1908199A (enExample) |
| BR (1) | BR9815363A (enExample) |
| CA (2) | CA2730373A1 (enExample) |
| DK (1) | DK1037926T3 (enExample) |
| ES (1) | ES2450922T3 (enExample) |
| IL (4) | IL136201A0 (enExample) |
| NO (2) | NO20002957L (enExample) |
| NZ (1) | NZ504597A (enExample) |
| TR (1) | TR200001689T2 (enExample) |
| WO (1) | WO1999031140A1 (enExample) |
| ZA (1) | ZA9811162B (enExample) |
Families Citing this family (105)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2697752B1 (fr) | 1992-11-10 | 1995-04-14 | Rhone Poulenc Rorer Sa | Compositions antitumorales contenant des dérivés du taxane. |
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| US6972170B1 (en) | 1997-12-01 | 2005-12-06 | Sloan-Kettering Institute For Cancer Research | Markers for prostate cancer |
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| US6417168B1 (en) | 1998-03-04 | 2002-07-09 | The Trustees Of The University Of Pennsylvania | Compositions and methods of treating tumors |
| US6316462B1 (en) | 1999-04-09 | 2001-11-13 | Schering Corporation | Methods of inducing cancer cell death and tumor regression |
| US6333348B1 (en) | 1999-04-09 | 2001-12-25 | Aventis Pharma S.A. | Use of docetaxel for treating cancers |
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| CA2375228A1 (en) * | 1999-06-10 | 2000-12-21 | Sloan-Kettering Institute For Cancer Research | Markers for prostate cancer |
| ES2466715T3 (es) * | 1999-06-25 | 2014-06-11 | Immunogen, Inc. | Métodos de tratamiento usando conjugados de anticuerpo anti-ErbB-maitansinoide |
| US20030086924A1 (en) * | 1999-06-25 | 2003-05-08 | Genentech, Inc. | Treatment with anti-ErbB2 antibodies |
| US7041292B1 (en) | 1999-06-25 | 2006-05-09 | Genentech, Inc. | Treating prostate cancer with anti-ErbB2 antibodies |
| US6949245B1 (en) | 1999-06-25 | 2005-09-27 | Genentech, Inc. | Humanized anti-ErbB2 antibodies and treatment with anti-ErbB2 antibodies |
| RU2270029C2 (ru) * | 1999-06-25 | 2006-02-20 | Джинентех, Инк. | ГУМАНИЗИРОВАННОЕ АНТИТЕЛО, КОТОРОЕ ОБЛАДАЕТ СПОСОБНОСТЬЮ СВЯЗЫВАТЬ ErbB2 И БЛОКИРОВАТЬ АКТИВАЦИЮ ЛИГАНДОМ РЕЦЕПТОРА ErbB (ВАРИАНТЫ) И КОМПОЗИЦИЯ ДЛЯ ПРИМЕНЕНИЯ ПРИ ЛЕЧЕНИИ РАКА, СОДЕРЖАЩАЯ ЭТО АНТИТЕЛО |
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2010
- 2010-04-07 JP JP2010088515A patent/JP2010209081A/ja active Pending
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2011
- 2011-05-09 US US13/103,799 patent/US8309087B2/en not_active Expired - Fee Related
- 2011-07-14 IL IL214084A patent/IL214084A/en not_active IP Right Cessation
- 2011-07-18 US US13/185,329 patent/US8425908B2/en not_active Expired - Fee Related
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2012
- 2012-10-04 JP JP2012222108A patent/JP2013056887A/ja not_active Withdrawn
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2013
- 2013-03-15 US US13/841,146 patent/US20130209459A1/en not_active Abandoned
- 2013-12-26 US US14/141,232 patent/US20140341886A1/en not_active Abandoned
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2014
- 2014-09-17 IL IL234696A patent/IL234696A/en not_active IP Right Cessation
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2015
- 2015-06-09 JP JP2015116874A patent/JP2016006046A/ja not_active Withdrawn
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2016
- 2016-09-23 JP JP2016185281A patent/JP2017039737A/ja active Pending
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2017
- 2017-04-05 JP JP2017075241A patent/JP2017165737A/ja not_active Withdrawn
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2018
- 2018-12-05 JP JP2018227941A patent/JP2019055979A/ja active Pending
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2019
- 2019-04-23 US US16/392,300 patent/US20190240185A1/en not_active Abandoned
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