JP2013533212A5 - - Google Patents
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- Publication number
- JP2013533212A5 JP2013533212A5 JP2013509316A JP2013509316A JP2013533212A5 JP 2013533212 A5 JP2013533212 A5 JP 2013533212A5 JP 2013509316 A JP2013509316 A JP 2013509316A JP 2013509316 A JP2013509316 A JP 2013509316A JP 2013533212 A5 JP2013533212 A5 JP 2013533212A5
- Authority
- JP
- Japan
- Prior art keywords
- analog
- group
- compound
- alkyl
- fluoro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33212410P | 2010-05-06 | 2010-05-06 | |
| US61/332,124 | 2010-05-06 | ||
| PCT/US2011/035651 WO2011140525A2 (en) | 2010-05-06 | 2011-05-06 | Methods and compositions related to a retinoid receptor-selective pathway |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016132716A Division JP6375340B2 (ja) | 2010-05-06 | 2016-07-04 | レチノイド受容体に選択的な経路に関する方法および組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013533212A JP2013533212A (ja) | 2013-08-22 |
| JP2013533212A5 true JP2013533212A5 (enExample) | 2014-07-10 |
Family
ID=44904518
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013509316A Pending JP2013533212A (ja) | 2010-05-06 | 2011-05-06 | レチノイド受容体に選択的な経路に関する方法および組成物 |
| JP2016132716A Expired - Fee Related JP6375340B2 (ja) | 2010-05-06 | 2016-07-04 | レチノイド受容体に選択的な経路に関する方法および組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016132716A Expired - Fee Related JP6375340B2 (ja) | 2010-05-06 | 2016-07-04 | レチノイド受容体に選択的な経路に関する方法および組成物 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US9611235B2 (enExample) |
| EP (1) | EP2571497B1 (enExample) |
| JP (2) | JP2013533212A (enExample) |
| KR (1) | KR101889290B1 (enExample) |
| CN (2) | CN107050007B (enExample) |
| AU (1) | AU2011249857B2 (enExample) |
| CA (1) | CA2798692C (enExample) |
| ES (1) | ES2702532T3 (enExample) |
| WO (1) | WO2011140525A2 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101889290B1 (ko) | 2010-05-06 | 2018-08-20 | 샌포드 번햄 프레비즈 메디컬 디스커버리 인스티튜트 | 레티노이드 수용체-선택적 경로와 관련된 방법 및 조성물 |
| WO2012135650A1 (en) * | 2011-04-01 | 2012-10-04 | Southern Research Institute | Derivatives of sulindac, use thereof and preparation thereof |
| WO2015100267A1 (en) * | 2013-12-23 | 2015-07-02 | Sanford-Burnham Medical Research Institute | Methods and compositions for treating cancer |
| WO2017193086A1 (en) * | 2016-05-06 | 2017-11-09 | Tarrex Biopharma Inc. | Therapeutic compounds and methods |
| EP4165009A4 (en) * | 2020-06-12 | 2024-10-02 | Nucmito Pharmaceuticals Co., Ltd. | Indene compounds, pharmaceutical compositions thereof, and their therapeutic applications |
| US20240034785A1 (en) * | 2020-12-07 | 2024-02-01 | Nucmito Pharmaceuticals Co. Ltd. | Rxr-alpha binders and rxr-alpha/plk1 modulators |
| EP4337628A4 (en) * | 2021-05-15 | 2025-08-27 | Nucmito Pharmaceuticals Company Ltd | INDENE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS BASED THEREON AND THEIR THERAPEUTIC APPLICATIONS |
| EP4619369A1 (en) * | 2022-11-16 | 2025-09-24 | Nucmito Pharmaceuticals Co., Ltd. | Indene compounds, pharmaceutical compositions thereof, and their therapeutic applications |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001012858A1 (en) | 1999-08-16 | 2001-02-22 | The Johns Hopkins University | PPARδ LINKS APC TO CHEMOPREVENTIVE DRUGS |
| DE10163426A1 (de) * | 2001-12-21 | 2003-07-03 | Max Planck Gesellschaft | Pharmakologisch wirksame Inden-Derivate |
| WO2004047772A2 (en) * | 2002-11-26 | 2004-06-10 | Florida Atlantic University | Catalytic antioxidants and methods of use |
| WO2005037189A2 (en) | 2003-08-13 | 2005-04-28 | The Burnham Institute | Cytoplasmic activity of retinoid x receptor and its regulation by ligands and dimerization |
| JP2005247807A (ja) * | 2004-03-08 | 2005-09-15 | Japan Science & Technology Agency | Ｎｓａｉｄを利用した癌治療用組成物 |
| US8258181B2 (en) * | 2005-03-23 | 2012-09-04 | Florida Atlantic University | Treatment or prevention of cancer and precancerous disorders |
| EP1968616A4 (en) * | 2006-01-04 | 2009-10-21 | Southern Res Inst | DERIVATIVES OF SULINDAC, USE AND PREPARATION THEREOF |
| WO2010070379A1 (en) | 2008-12-17 | 2010-06-24 | Centre National De La Recherche Scientifique | Rxr-ppargamma agonist/growth factor inhibitor combination therapy for inducing apoptosis and the treatment of cancer |
| KR101889290B1 (ko) | 2010-05-06 | 2018-08-20 | 샌포드 번햄 프레비즈 메디컬 디스커버리 인스티튜트 | 레티노이드 수용체-선택적 경로와 관련된 방법 및 조성물 |
| CN102030642A (zh) | 2010-12-03 | 2011-04-27 | 厦门大学 | 舒林酸类似物的中间体的合成方法与应用 |
| WO2015100267A1 (en) | 2013-12-23 | 2015-07-02 | Sanford-Burnham Medical Research Institute | Methods and compositions for treating cancer |
| WO2017193086A1 (en) | 2016-05-06 | 2017-11-09 | Tarrex Biopharma Inc. | Therapeutic compounds and methods |
-
2011
- 2011-05-06 KR KR1020127031894A patent/KR101889290B1/ko not_active Expired - Fee Related
- 2011-05-06 CN CN201611020419.9A patent/CN107050007B/zh not_active Expired - Fee Related
- 2011-05-06 CN CN201180030974.9A patent/CN103002887B/zh not_active Expired - Fee Related
- 2011-05-06 AU AU2011249857A patent/AU2011249857B2/en not_active Ceased
- 2011-05-06 EP EP11778467.8A patent/EP2571497B1/en not_active Not-in-force
- 2011-05-06 WO PCT/US2011/035651 patent/WO2011140525A2/en not_active Ceased
- 2011-05-06 ES ES11778467T patent/ES2702532T3/es active Active
- 2011-05-06 CA CA2798692A patent/CA2798692C/en not_active Expired - Fee Related
- 2011-05-06 US US13/102,475 patent/US9611235B2/en not_active Expired - Fee Related
- 2011-05-06 JP JP2013509316A patent/JP2013533212A/ja active Pending
-
2016
- 2016-07-04 JP JP2016132716A patent/JP6375340B2/ja not_active Expired - Fee Related
-
2017
- 2017-02-16 US US15/435,125 patent/US10087156B2/en not_active Expired - Fee Related
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