JP2013526497A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2013526497A5 JP2013526497A5 JP2013509505A JP2013509505A JP2013526497A5 JP 2013526497 A5 JP2013526497 A5 JP 2013526497A5 JP 2013509505 A JP2013509505 A JP 2013509505A JP 2013509505 A JP2013509505 A JP 2013509505A JP 2013526497 A5 JP2013526497 A5 JP 2013526497A5
- Authority
- JP
- Japan
- Prior art keywords
- formula
- salt
- solvate
- diyl
- medicament
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 Cc1cc(-c2nc(-c3ccc(*)cc3)n[o]2)n[n]1Cc1cccc(*)c1 Chemical compound Cc1cc(-c2nc(-c3ccc(*)cc3)n[o]2)n[n]1Cc1cccc(*)c1 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10004855 | 2010-05-08 | ||
| EP10004855.2 | 2010-05-08 | ||
| PCT/EP2011/057021 WO2011141326A1 (de) | 2010-05-08 | 2011-05-03 | Substituierte heterocyclylbenzyl-pyrazole und ihre verwendung |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013526497A JP2013526497A (ja) | 2013-06-24 |
| JP2013526497A5 true JP2013526497A5 (cg-RX-API-DMAC10.html) | 2014-06-26 |
| JP5727002B2 JP5727002B2 (ja) | 2015-06-03 |
Family
ID=44063276
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013509505A Expired - Fee Related JP5727002B2 (ja) | 2010-05-08 | 2011-05-03 | 置換ヘテロサイクリルベンジルピラゾール類およびその使用 |
Country Status (26)
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101688247A (zh) * | 2007-05-01 | 2010-03-31 | 希尔氏宠物营养品公司 | 猫科动物骨关节炎的诊断方法和组合物 |
| WO2008141731A2 (en) * | 2007-05-18 | 2008-11-27 | Bayer Healthcare Ag | Inhibitors of hypoxia inducible factor (hif) useful for treating hyper-proliferative disorders and diseases associated with angiogenesis |
| EA201291167A1 (ru) * | 2010-05-08 | 2013-05-30 | Байер Интеллектуэль Проперти Гмбх | Замещенные гетероциклилбензилпиразолы и их применение |
| UA114915C2 (uk) | 2012-07-02 | 2017-08-28 | Монсанто Текнолоджи Ллс | Спосіб одержання 3,5-дизаміщених 1,2,4-оксадіазолів (варіанти) |
| WO2014031928A2 (en) * | 2012-08-24 | 2014-02-27 | Philip Jones | Heterocyclic modulators of hif activity for treatment of disease |
| EP2888253A4 (en) | 2012-08-24 | 2016-01-06 | Univ Texas | HETEROCYCLIC HIF ACTIVITY MODULATORS FOR THE TREATMENT OF DISEASES |
| DK2888255T3 (en) | 2012-08-24 | 2018-10-29 | Univ Texas | HETOCYCLIC MODULATORS OF HIF ACTIVITY FOR TREATMENT OF DISEASE |
| WO2015130790A2 (en) | 2014-02-25 | 2015-09-03 | Board Of Regents, University Of Texas System | Salts of heterocyclic modulators of hif activity for treatment of disease |
| US10191597B2 (en) | 2015-06-30 | 2019-01-29 | Synaptics Incorporated | Modulating a reference voltage to preform capacitive sensing |
| WO2018131657A1 (ja) * | 2017-01-13 | 2018-07-19 | 日産化学工業株式会社 | 芳香族ジアミン化合物前駆体の製造方法 |
| WO2021216530A1 (en) | 2020-04-20 | 2021-10-28 | Akebia Therapeutics, Inc. | Treatment of viral infections, of organ injury, and of related conditions using a hif prolyl hydroxylase inhibitor or a hif-alpha stabilizer |
| CN115944626B (zh) * | 2022-12-08 | 2024-04-19 | 桂林医学院附属医院 | 小分子化合物在制备抗缺氧或缺血再灌注损伤药物中的应用 |
| AU2024371427A1 (en) * | 2023-10-30 | 2026-06-04 | Pretzel Therapeutics, Inc. | Compositions and inhibitors of polrmt |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6610726B2 (en) * | 2001-06-29 | 2003-08-26 | North Shore-Long Island Jewish Research Institute | Compositions and agents for modulating cellular proliferation and angiogenesis |
| EP1613614A2 (en) | 2003-04-03 | 2006-01-11 | Merck & Co., Inc. | Di-aryl substituted pyrazole modulators of metabotropic glutamate receptor-5 |
| CN1842332A (zh) * | 2003-06-30 | 2006-10-04 | Hif生物公司 | 化合物、组合物及方法 |
| JP4499721B2 (ja) | 2003-06-30 | 2010-07-07 | ヒフ バイオ，インク． | 化合物、組成物および方法 |
| GB0508472D0 (en) * | 2005-04-26 | 2005-06-01 | Glaxo Group Ltd | Compounds |
| WO2007065010A2 (en) | 2005-12-02 | 2007-06-07 | Hif Bio, Inc. | Anti-angiogenesis compounds |
| WO2008141731A2 (en) * | 2007-05-18 | 2008-11-27 | Bayer Healthcare Ag | Inhibitors of hypoxia inducible factor (hif) useful for treating hyper-proliferative disorders and diseases associated with angiogenesis |
| CA2743424A1 (en) * | 2008-11-14 | 2010-05-20 | Michael Haerter | Heteroaromatic compounds for use as hif inhibitors |
| DE102008057344A1 (de) * | 2008-11-14 | 2010-05-20 | Bayer Schering Pharma Aktiengesellschaft | Aminoalkyl-substituierte Aryl-Verbindungen und ihre Verwendung |
| AU2009316019A1 (en) * | 2008-11-14 | 2010-05-20 | Bayer Intellectual Property Gmbh | Heterocyclically substituted aryl compounds as HIF inhibitors |
| EP2202232A1 (en) | 2008-12-26 | 2010-06-30 | Laboratorios Almirall, S.A. | 1,2,4-oxadiazole derivatives and their therapeutic use |
| ES2405054T3 (es) | 2009-01-23 | 2013-05-30 | Bristol-Myers Squibb Company | Derivados de pirazol-1,2,4-oxadiazol como agonistas de esfingosina-1-fosfato |
| EA201291167A1 (ru) * | 2010-05-08 | 2013-05-30 | Байер Интеллектуэль Проперти Гмбх | Замещенные гетероциклилбензилпиразолы и их применение |
-
2011
- 2011-05-03 EA EA201291167A patent/EA201291167A1/ru unknown
- 2011-05-03 US US13/696,878 patent/US20130172311A1/en not_active Abandoned
- 2011-05-03 EP EP11716595.1A patent/EP2569312B1/de active Active
- 2011-05-03 BR BR112012028651A patent/BR112012028651A2/pt not_active IP Right Cessation
- 2011-05-03 WO PCT/EP2011/057021 patent/WO2011141326A1/de not_active Ceased
- 2011-05-03 MA MA35350A patent/MA34939B1/fr unknown
- 2011-05-03 JP JP2013509505A patent/JP5727002B2/ja not_active Expired - Fee Related
- 2011-05-03 KR KR1020127032069A patent/KR20130108997A/ko not_active Withdrawn
- 2011-05-03 SG SG2012082145A patent/SG185459A1/en unknown
- 2011-05-03 CA CA2798375A patent/CA2798375A1/en not_active Abandoned
- 2011-05-03 PE PE2012002121A patent/PE20130228A1/es not_active Application Discontinuation
- 2011-05-03 ES ES11716595.1T patent/ES2462522T3/es active Active
- 2011-05-03 PH PH1/2012/502202A patent/PH12012502202A1/en unknown
- 2011-05-03 MX MX2012012960A patent/MX2012012960A/es active IP Right Grant
- 2011-05-03 CN CN201180033637.5A patent/CN103003269B/zh not_active Expired - Fee Related
- 2011-05-03 AU AU2011252223A patent/AU2011252223A1/en not_active Abandoned
- 2011-05-04 UY UY0001033369A patent/UY33369A/es not_active Application Discontinuation
- 2011-05-04 AR ARP110101533A patent/AR081368A1/es not_active Application Discontinuation
- 2011-05-06 TW TW100115869A patent/TW201200510A/zh unknown
- 2011-05-09 US US13/103,305 patent/US8470811B2/en not_active Expired - Fee Related
-
2012
- 2012-11-05 IL IL222851A patent/IL222851A0/en unknown
- 2012-11-07 CU CU2012000157A patent/CU20120157A7/es unknown
- 2012-11-07 TN TNP2012000531A patent/TN2012000531A1/en unknown
- 2012-11-07 DO DO2012000284A patent/DOP2012000284A/es unknown
- 2012-11-08 CR CR20120570A patent/CR20120570A/es unknown
- 2012-11-08 EC ECSP12012288 patent/ECSP12012288A/es unknown
- 2012-11-08 CO CO12201711A patent/CO6640218A2/es not_active Application Discontinuation