JP2013523846A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2013523846A5 JP2013523846A5 JP2013504075A JP2013504075A JP2013523846A5 JP 2013523846 A5 JP2013523846 A5 JP 2013523846A5 JP 2013504075 A JP2013504075 A JP 2013504075A JP 2013504075 A JP2013504075 A JP 2013504075A JP 2013523846 A5 JP2013523846 A5 JP 2013523846A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- compound according
- disorder
- condition
- pharmaceutical composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 150000001875 compounds Chemical class 0.000 claims 24
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 6
- 201000010099 disease Diseases 0.000 claims 3
- 208000035475 disorder Diseases 0.000 claims 3
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- 208000022873 Ocular disease Diseases 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 206010012689 Diabetic retinopathy Diseases 0.000 claims 1
- 201000010183 Papilledema Diseases 0.000 claims 1
- 206010038886 Retinal oedema Diseases 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 claims 1
- 206010064930 age-related macular degeneration Diseases 0.000 claims 1
- 230000033115 angiogenesis Effects 0.000 claims 1
- 210000002987 choroid plexus Anatomy 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 208000002780 macular degeneration Diseases 0.000 claims 1
- 239000000651 prodrug Substances 0.000 claims 1
- 229940002612 prodrug Drugs 0.000 claims 1
- 201000011195 retinal edema Diseases 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 239000012453 solvate Substances 0.000 claims 1
- 0 C*(CCNCc1ccc(-c2cc(nccc3CCOc(ccc(NC(NC4CC4)=O)c4)c4F)c3[s]2)nc1)=O Chemical compound C*(CCNCc1ccc(-c2cc(nccc3CCOc(ccc(NC(NC4CC4)=O)c4)c4F)c3[s]2)nc1)=O 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32480310P | 2010-04-16 | 2010-04-16 | |
| US61/324,803 | 2010-04-16 | ||
| PCT/CA2011/000390 WO2011127565A1 (en) | 2010-04-16 | 2011-04-08 | Inhibitors of protein tyrosine kinase activity and use thereof to treat ophthalmic disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013523846A JP2013523846A (ja) | 2013-06-17 |
| JP2013523846A5 true JP2013523846A5 (enExample) | 2014-05-15 |
Family
ID=44788641
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013504075A Ceased JP2013523846A (ja) | 2010-04-16 | 2011-04-08 | タンパク質チロシンキナーゼ活性の阻害剤および眼部の障害を治療するためのそれらの使用 |
| JP2013504076A Ceased JP2013525286A (ja) | 2010-04-16 | 2011-04-08 | タンパク質チロシンキナーゼ活性の阻害剤 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013504076A Ceased JP2013525286A (ja) | 2010-04-16 | 2011-04-08 | タンパク質チロシンキナーゼ活性の阻害剤 |
Country Status (19)
| Country | Link |
|---|---|
| US (3) | US8906852B2 (enExample) |
| EP (2) | EP2563794A4 (enExample) |
| JP (2) | JP2013523846A (enExample) |
| KR (2) | KR20130058006A (enExample) |
| CN (2) | CN102947315A (enExample) |
| AR (2) | AR080871A1 (enExample) |
| AU (2) | AU2011241422B2 (enExample) |
| CA (2) | CA2796008A1 (enExample) |
| CO (2) | CO6640224A2 (enExample) |
| EA (2) | EA201291052A1 (enExample) |
| MX (2) | MX2012012031A (enExample) |
| MY (1) | MY157319A (enExample) |
| NZ (2) | NZ602954A (enExample) |
| PH (2) | PH12012502070A1 (enExample) |
| SG (2) | SG184883A1 (enExample) |
| TW (2) | TW201204735A (enExample) |
| UA (1) | UA108878C2 (enExample) |
| WO (2) | WO2011127567A1 (enExample) |
| ZA (2) | ZA201207482B (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2183254B1 (en) * | 2007-08-29 | 2017-06-21 | MethylGene Inc. | Inhibitors of protein tyrosine kinase activity |
| MX2010009729A (es) * | 2008-03-05 | 2010-12-21 | Methylgene Inc | Inhibidores de actividad de proteina tirosina quinasa. |
| MX2012012031A (es) * | 2010-04-16 | 2012-12-17 | Methylgene Inc | Inhibidores de la actividad de la proteina tirosina quinasa y uso de los mismos para tratar transtornos oftalmicos. |
| US20130090327A1 (en) * | 2011-09-30 | 2013-04-11 | Methylgene Inc. | Inhibitors of Protein Tyrosine Kinase Activity |
| WO2013044361A1 (en) * | 2011-09-30 | 2013-04-04 | Methylgene Inc. | Inhibitors of protein tyrosine kinase activity |
| US20130096135A1 (en) * | 2011-09-30 | 2013-04-18 | Methylgene Inc. | Selected Inhibitors of Protein Tyrosine Kinase Activity |
| ES2593533T3 (es) | 2011-12-15 | 2016-12-09 | Pfizer Limited | Derivados de sulfonamida |
| EP3200589B1 (en) | 2014-09-10 | 2026-03-11 | Temple University Of The Commonwealth System Of Higher Education | Novel 5-hydroxytryptamine receptor 7 activity modulators and their method of use |
| US20180221365A1 (en) * | 2015-05-12 | 2018-08-09 | Temple University-Of The Commonwealth System Of Higher Education | Novel sigma-2 receptor binders and their method of use |
| JP6664170B2 (ja) * | 2015-08-31 | 2020-03-13 | 広栄化学工業株式会社 | アミノヒドロキシピリジン化合物の製造方法 |
| CN108530464B (zh) * | 2017-03-02 | 2020-10-27 | 深圳海王医药科技研究院有限公司 | 一种多靶点激酶抑制剂 |
| CN121108077A (zh) * | 2025-09-02 | 2025-12-12 | 领泰生物医药(绍兴)有限公司 | 一种含氮杂环化合物的制备方法及其中间体 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050020619A1 (en) * | 2003-07-24 | 2005-01-27 | Patrick Betschmann | Thienopyridine kinase inhibitors |
| EP1781664B1 (en) * | 2004-07-30 | 2013-09-04 | MethylGene Inc. | Inhibitors of vegf receptor and hgf receptor signaling |
| AU2006229343A1 (en) * | 2005-03-28 | 2006-10-05 | Kirin Pharma Kabushiki Kaisha | Thienopyridine derivative, or quinoline derivative, or quinazoline derivative, having c-Met autophosphorylation inhibiting potency |
| JO2787B1 (en) * | 2005-04-27 | 2014-03-15 | امجين إنك, | Alternative amide derivatives and methods of use |
| MX2007014617A (es) * | 2005-05-20 | 2008-02-11 | Methylgene Inc | Inhibidores de senalizacion de receptor de factor de crecimiento endotelial bascular y receptor de factor de crecimiento de hepatocitos. |
| WO2008041053A2 (en) | 2005-05-20 | 2008-04-10 | Methylgene, Inc. | Inhibitors of vegf receptor and hgf receptor signaling |
| EP2183254B1 (en) * | 2007-08-29 | 2017-06-21 | MethylGene Inc. | Inhibitors of protein tyrosine kinase activity |
| WO2009026720A1 (en) * | 2007-08-29 | 2009-03-05 | Methylgene Inc. | Processes and intermediates for preparing fused heterocyclic kinase inhibitors |
| MX2010009729A (es) * | 2008-03-05 | 2010-12-21 | Methylgene Inc | Inhibidores de actividad de proteina tirosina quinasa. |
| MX2012012031A (es) * | 2010-04-16 | 2012-12-17 | Methylgene Inc | Inhibidores de la actividad de la proteina tirosina quinasa y uso de los mismos para tratar transtornos oftalmicos. |
| WO2013044361A1 (en) * | 2011-09-30 | 2013-04-04 | Methylgene Inc. | Inhibitors of protein tyrosine kinase activity |
-
2011
- 2011-04-08 MX MX2012012031A patent/MX2012012031A/es active IP Right Grant
- 2011-04-08 EP EP20110768305 patent/EP2563794A4/en not_active Withdrawn
- 2011-04-08 EA EA201291052A patent/EA201291052A1/ru unknown
- 2011-04-08 AR ARP110101191A patent/AR080871A1/es unknown
- 2011-04-08 EA EA201291055A patent/EA201291055A1/ru unknown
- 2011-04-08 AU AU2011241422A patent/AU2011241422B2/en not_active Ceased
- 2011-04-08 US US13/082,923 patent/US8906852B2/en not_active Expired - Fee Related
- 2011-04-08 PH PH1/2012/502070A patent/PH12012502070A1/en unknown
- 2011-04-08 UA UAA201211687A patent/UA108878C2/ru unknown
- 2011-04-08 JP JP2013504075A patent/JP2013523846A/ja not_active Ceased
- 2011-04-08 KR KR1020127030161A patent/KR20130058006A/ko not_active Withdrawn
- 2011-04-08 EP EP11768307.8A patent/EP2563795A4/en not_active Withdrawn
- 2011-04-08 CN CN2011800297313A patent/CN102947315A/zh active Pending
- 2011-04-08 CA CA2796008A patent/CA2796008A1/en not_active Abandoned
- 2011-04-08 TW TW100112308A patent/TW201204735A/zh unknown
- 2011-04-08 SG SG2012076733A patent/SG184883A1/en unknown
- 2011-04-08 WO PCT/CA2011/000394 patent/WO2011127567A1/en not_active Ceased
- 2011-04-08 WO PCT/CA2011/000390 patent/WO2011127565A1/en not_active Ceased
- 2011-04-08 SG SG2012076725A patent/SG184882A1/en unknown
- 2011-04-08 NZ NZ602954A patent/NZ602954A/en not_active IP Right Cessation
- 2011-04-08 US US13/082,944 patent/US8455484B2/en not_active Expired - Fee Related
- 2011-04-08 JP JP2013504076A patent/JP2013525286A/ja not_active Ceased
- 2011-04-08 TW TW100112307A patent/TW201204734A/zh unknown
- 2011-04-08 KR KR1020127029841A patent/KR20130100234A/ko not_active Withdrawn
- 2011-04-08 MY MYPI2012004621A patent/MY157319A/en unknown
- 2011-04-08 PH PH1/2012/502073A patent/PH12012502073A1/en unknown
- 2011-04-08 AU AU2011241420A patent/AU2011241420B2/en not_active Ceased
- 2011-04-08 NZ NZ602948A patent/NZ602948A/en not_active IP Right Cessation
- 2011-04-08 AR ARP110101195A patent/AR080875A1/es unknown
- 2011-04-08 CN CN201180029735.1A patent/CN103025740B/zh not_active Expired - Fee Related
- 2011-04-08 MX MX2012012032A patent/MX2012012032A/es not_active Application Discontinuation
- 2011-04-08 CA CA2796054A patent/CA2796054A1/en not_active Abandoned
-
2012
- 2012-10-05 ZA ZA2012/07482A patent/ZA201207482B/en unknown
- 2012-10-09 ZA ZA2012/07557A patent/ZA201207557B/en unknown
- 2012-11-15 CO CO12207317A patent/CO6640224A2/es active IP Right Grant
- 2012-11-15 CO CO12207310A patent/CO6630193A2/es active IP Right Grant
-
2014
- 2014-06-18 US US14/308,408 patent/US20140315801A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2015523546A5 (enExample) | ||
| PH12015501942A1 (en) | Susbtituted 3-phenylpropylamine derivatives for the treatment of opthalmic diseases and disorders | |
| JP2016505637A5 (enExample) | ||
| JP2013526544A5 (enExample) | ||
| RU2016151420A (ru) | Новое терапевтическое применение производных бензилиденгуанидина для лечения протеинопатий | |
| IN2014CN00989A (enExample) | ||
| JP2016515561A5 (enExample) | ||
| JP2014511891A5 (enExample) | ||
| JP2015511958A5 (enExample) | ||
| WO2013174930A3 (en) | 7-oxo-thiazolopyridine carbonic acid derivatives and their use in the treatment, amelioration or prevention of a viral disease | |
| MX2017013483A (es) | Compuestos y su uso como inhibidores de ?-secretasa 1 (bace1). | |
| JP2016540749A5 (enExample) | ||
| JP2013500977A5 (enExample) | ||
| JP2013522326A5 (enExample) | ||
| BR112014008759A2 (pt) | tratamento de doença ocular | |
| WO2013166037A9 (en) | Non-retinoid antagonists for treatment of eye disorders | |
| JP2016027060A5 (enExample) | ||
| JP2016522254A5 (enExample) | ||
| AR062395A1 (es) | Uso de derivados del 2.5-dihidroxibenceno para el tratamiento de enfermedades oculares | |
| JP2021503449A5 (enExample) | ||
| JP2019529514A5 (enExample) | ||
| CN111526878A (zh) | 含三萜类化合物的药物组合物及其用途 | |
| HK1212688A1 (zh) | 吡啶酮衍生物及其在治疗、改善或预防病毒疾病中的用途 | |
| JP2017505809A5 (enExample) | ||
| JP2017525758A5 (enExample) |