JP2013522273A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2013522273A5 JP2013522273A5 JP2012557537A JP2012557537A JP2013522273A5 JP 2013522273 A5 JP2013522273 A5 JP 2013522273A5 JP 2012557537 A JP2012557537 A JP 2012557537A JP 2012557537 A JP2012557537 A JP 2012557537A JP 2013522273 A5 JP2013522273 A5 JP 2013522273A5
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- alkyl
- oxo
- quin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10156681 | 2010-03-16 | ||
| EP10156681.8 | 2010-03-16 | ||
| PCT/EP2011/053957 WO2011113859A1 (en) | 2010-03-16 | 2011-03-16 | Processes and intermediates for preparing a macrocyclic protease inhibitor of hcv |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016021576A Division JP2016164143A (ja) | 2010-03-16 | 2016-02-08 | Ｈｃｖの大環状プロテアーゼ阻害剤の製造のための方法及び中間体 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013522273A JP2013522273A (ja) | 2013-06-13 |
| JP2013522273A5 true JP2013522273A5 (cg-RX-API-DMAC10.html) | 2014-06-19 |
Family
ID=42342793
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012557537A Withdrawn JP2013522273A (ja) | 2010-03-16 | 2011-03-16 | Ｈｃｖの大環状プロテアーゼ阻害剤の製造のための方法及び中間体 |
| JP2016021576A Pending JP2016164143A (ja) | 2010-03-16 | 2016-02-08 | Ｈｃｖの大環状プロテアーゼ阻害剤の製造のための方法及び中間体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016021576A Pending JP2016164143A (ja) | 2010-03-16 | 2016-02-08 | Ｈｃｖの大環状プロテアーゼ阻害剤の製造のための方法及び中間体 |
Country Status (12)
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2547645B1 (en) * | 2010-03-16 | 2018-07-04 | Janssen Pharmaceuticals, Inc. | Processes and intermediates for preparing a macrocyclic protease inhibitor of hcv |
| TWI565704B (zh) | 2011-09-22 | 2017-01-11 | 健生醫藥公司 | 用於製備ｈｃｖ巨環蛋白酶抑制劑之方法及中間物 |
| WO2016105333A1 (en) * | 2014-12-22 | 2016-06-30 | Colgate-Palmolive Company | Unit dose fabric softener |
| MA41812A (fr) | 2015-03-27 | 2018-01-30 | Janssen Pharmaceuticals Inc | Procédés et intermédiaires pour la préparation d'un inhibiteur de protéase macrocyclique du vhc |
| WO2023220559A2 (en) * | 2022-05-09 | 2023-11-16 | The Scripps Research Institute | Catalyst-controlled site-selective methylene c-h lactonization of dicarboxylic acids |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL8300536A (nl) | 1983-02-14 | 1984-09-03 | Oce Andeno Bv | Optisch actief alfa-azido-p-hydroxyfenylazijnzuur en zijn zouten alsmede de bereiding daarvan. |
| JPS6124539A (ja) * | 1984-07-11 | 1986-02-03 | Sagami Chem Res Center | 光学活性（ｒ）−２，５，１２−トリヒドロキシ−１，２，３，４−テトラヒドロナフタセン−６，１１−ジオン−２−カルボン酸の取得方法 |
| JPH06124539A (ja) | 1992-10-08 | 1994-05-06 | Sony Corp | ディジタルｖｔｒ |
| JPH08231469A (ja) | 1995-02-23 | 1996-09-10 | Nippon Kayaku Co Ltd | シクロペンタンカルボン酸誘導体及びその製造法 |
| JPH11180930A (ja) * | 1997-12-22 | 1999-07-06 | Sumitomo Chem Co Ltd | 光学活性ｔｒａｎｓ−シクロブタンジカルボン酸類の製造方法 |
| DE10029139A1 (de) * | 2000-06-14 | 2002-01-03 | Sueddeutsche Kalkstickstoff | Verfahren zur Herstellung von Amiden oder Estern |
| ES2336009T3 (es) | 2004-01-30 | 2010-04-07 | Medivir Ab | Inhibidores de la ns-3 serina proteasa del vhc. |
| PE20070211A1 (es) * | 2005-07-29 | 2007-05-12 | Medivir Ab | Compuestos macrociclicos como inhibidores del virus de hepatitis c |
| ATE496042T1 (de) * | 2005-07-29 | 2011-02-15 | Tibotec Pharm Ltd | Makrocyclische inhibitoren des hepatitis-c-virus |
| US20070185346A1 (en) * | 2006-02-03 | 2007-08-09 | Vaidya Niteen A | Kit for automated resolving agent selection and method thereof |
| RU2483067C2 (ru) * | 2007-02-01 | 2013-05-27 | Тиботек Фармасьютикалз Лтд. | Способы и промежуточные продукты для получения макроциклического ингибитора протеазы вируса гепатита с |
| EP2547645B1 (en) * | 2010-03-16 | 2018-07-04 | Janssen Pharmaceuticals, Inc. | Processes and intermediates for preparing a macrocyclic protease inhibitor of hcv |
-
2011
- 2011-03-16 EP EP11709692.5A patent/EP2547645B1/en active Active
- 2011-03-16 CN CN2011800140694A patent/CN103249708A/zh active Pending
- 2011-03-16 RU RU2012143977A patent/RU2628081C2/ru not_active IP Right Cessation
- 2011-03-16 WO PCT/EP2011/053957 patent/WO2011113859A1/en not_active Ceased
- 2011-03-16 BR BR112012023296-7A patent/BR112012023296B1/pt not_active IP Right Cessation
- 2011-03-16 CA CA2793129A patent/CA2793129A1/en not_active Abandoned
- 2011-03-16 EP EP17166514.4A patent/EP3239129A1/en not_active Withdrawn
- 2011-03-16 KR KR1020127024789A patent/KR20130034012A/ko not_active Ceased
- 2011-03-16 US US13/634,996 patent/US9586893B2/en not_active Expired - Fee Related
- 2011-03-16 JP JP2012557537A patent/JP2013522273A/ja not_active Withdrawn
- 2011-03-16 AU AU2011229164A patent/AU2011229164B2/en not_active Ceased
- 2011-03-16 MX MX2012010678A patent/MX2012010678A/es active IP Right Grant
-
2012
- 2012-08-01 IL IL221242A patent/IL221242A/en not_active IP Right Cessation
-
2016
- 2016-02-08 JP JP2016021576A patent/JP2016164143A/ja active Pending
-
2017
- 2017-02-10 US US15/429,250 patent/US20170152253A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| KR101008364B1 (ko) | 라세믹 옥시라세탐, (ｓ)-옥시라세탐, 또는 그 유도체의 제조방법 | |
| JP2010524909A5 (cg-RX-API-DMAC10.html) | ||
| CN114555599A (zh) | 制备(4s)-(4-氰基-2-甲氧基苯基)-5-乙氧基-2,8-二甲基-1,4-二氢-1,6-萘啶-3-羧酸的酰氧基甲基酯的方法 | |
| CN107501112A (zh) | 一种手性β‑氨基酸的手性合成方法及医药中间体的合成方法 | |
| AU2008339583A1 (en) | Processes to pregabalin | |
| CN103467354B (zh) | 一种双吲哚甲烷衍生物的制备方法 | |
| RU2012143977A (ru) | Способы и промежуточные соединения для получения макроциклических ингибиторов протеазы hcv | |
| Zhao et al. | Enantioselective Michael addition of 3-aryloxindoles to a vinyl bisphosphonate ester catalyzed by a cinchona alkaloid derived thiourea catalyst | |
| CN106458853A (zh) | 一种不对称还原法制备西他列汀中间体的方法 | |
| JP5534460B2 (ja) | 光学活性なα−アミノアセタール類の製造方法 | |
| EP2970102B1 (en) | An improved process for the synthesis of melphalan and the hydrochloride salt | |
| EP3938370A1 (en) | Process for preparation of tofacitinib and pharmaceutically acceptable salt thereof | |
| CN112679522B (zh) | 一种巴洛沙韦中间体的制备方法 | |
| WO2010083722A1 (zh) | 一锅煮方法合成corey内酯的工艺 | |
| CN113754605B (zh) | 一种含氮配体及其制备方法和应用 | |
| JP2003512034A (ja) | キラルエステルの製造方法 | |
| Chen et al. | Synthetic studies on (+)-Biotin, part 15: a chiral squaramide-mediated Enantioselective Alcoholysis Approach toward the total synthesis of (+)-Biotin | |
| JP2010037206A (ja) | 光学活性なｏ−メチルセリンまたはその塩の製造法 | |
| ES2402174T3 (es) | Procedimiento de racemización de alfa-aminoacetales ópticamente activos | |
| JP5099932B2 (ja) | フルオレノンイミンを用いた炭素−炭素結合生成反応 | |
| AU2012311461B2 (en) | Processes and intermediates for preparing a macrocyclic protease inhibitor of HCV | |
| CN110981720A (zh) | 一种二芳基乙酸酯类化合物及制备方法 | |
| CN110511170A (zh) | 一种手性四氢吡咯-3-羧酸的合成方法 | |
| CA2660348C (en) | A novel process for preparing 3-amino-5-fluoro-4-dialkoxypentanoic acid ester | |
| JP2001026591A (ja) | アゾニアアダマンタン化合物およびこのものからのアザアダマンタン化合物の製造方法並びに該アゾニアアダマンタン化合物の製造方法 |