JP2013519909A - 対象物を走査する装置とその方法および顕微鏡 - Google Patents
対象物を走査する装置とその方法および顕微鏡 Download PDFInfo
- Publication number
- JP2013519909A JP2013519909A JP2012552408A JP2012552408A JP2013519909A JP 2013519909 A JP2013519909 A JP 2013519909A JP 2012552408 A JP2012552408 A JP 2012552408A JP 2012552408 A JP2012552408 A JP 2012552408A JP 2013519909 A JP2013519909 A JP 2013519909A
- Authority
- JP
- Japan
- Prior art keywords
- lens system
- focusing lens
- light beam
- illumination light
- front glass
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 title claims description 12
- 238000005286 illumination Methods 0.000 claims abstract description 56
- 239000011521 glass Substances 0.000 claims abstract description 43
- 238000007654 immersion Methods 0.000 claims description 21
- 238000002791 soaking Methods 0.000 claims description 13
- 239000006059 cover glass Substances 0.000 claims description 11
- 239000012528 membrane Substances 0.000 claims description 6
- 239000003795 chemical substances by application Substances 0.000 description 34
- 238000001514 detection method Methods 0.000 description 10
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 6
- 230000000694 effects Effects 0.000 description 6
- 230000003287 optical effect Effects 0.000 description 5
- 238000007598 dipping method Methods 0.000 description 4
- 239000013307 optical fiber Substances 0.000 description 3
- 230000000712 assembly Effects 0.000 description 2
- 238000000429 assembly Methods 0.000 description 2
- 238000002060 fluorescence correlation spectroscopy Methods 0.000 description 2
- 238000002866 fluorescence resonance energy transfer Methods 0.000 description 2
- 239000003921 oil Substances 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 238000001069 Raman spectroscopy Methods 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 239000003365 glass fiber Substances 0.000 description 1
- 238000003384 imaging method Methods 0.000 description 1
- 238000000671 immersion lithography Methods 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 description 1
- 229910052753 mercury Inorganic materials 0.000 description 1
- 238000000386 microscopy Methods 0.000 description 1
- 238000005498 polishing Methods 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
Images
Classifications
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/33—Immersion oils, or microscope systems or objectives for use with immersion fluids
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/0004—Microscopes specially adapted for specific applications
- G02B21/002—Scanning microscopes
- G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
- G02B21/0036—Scanning details, e.g. scanning stages
Landscapes
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Microscoopes, Condenser (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102010007728.3 | 2010-02-12 | ||
| DE102010007728A DE102010007728A1 (de) | 2010-02-12 | 2010-02-12 | Vorrichtung und Verfahren zum Scannen eines Objekts und Mikroskop |
| PCT/EP2011/052031 WO2011098557A1 (de) | 2010-02-12 | 2011-02-11 | Vorrichtung und verfahren zum scannen eines objekts und mikroskop |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013519909A true JP2013519909A (ja) | 2013-05-30 |
| JP2013519909A5 JP2013519909A5 (enExample) | 2014-03-20 |
Family
ID=43827842
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012552408A Pending JP2013519909A (ja) | 2010-02-12 | 2011-02-11 | 対象物を走査する装置とその方法および顕微鏡 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20130044370A1 (enExample) |
| JP (1) | JP2013519909A (enExample) |
| DE (1) | DE102010007728A1 (enExample) |
| WO (1) | WO2011098557A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2022071821A (ja) * | 2020-10-28 | 2022-05-16 | オリンパス株式会社 | 光信号検出装置、ゲル部材、光信号検出方法 |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102011051949B4 (de) | 2011-07-19 | 2017-05-18 | Leica Microsystems Cms Gmbh | Wechselvorrichtung für ein Mikroskop |
| US9159890B2 (en) * | 2013-02-15 | 2015-10-13 | Osram Opto Semiconductors Gmbh | Optoelectronic semiconductor component |
| DE102015118994B4 (de) * | 2014-11-07 | 2019-08-08 | Toyota Jidosha Kabushiki Kaisha | Steuerungssystem für ein Fahrzeug |
| AU2019207864B2 (en) * | 2018-01-12 | 2023-12-14 | Damae Medical | Dynamic focusing system for an optical device |
| DE102018221670A1 (de) * | 2018-12-13 | 2020-06-18 | Karlsruher Institut für Technologie | Vorrichtung und Verfahren zur optischen Charakterisierung oder Bearbeitung eines Objekts |
| US20230266577A1 (en) * | 2022-02-18 | 2023-08-24 | Purdue Research Foundation | Apparatuses and methods for high-speed laser scanning |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS62121417A (ja) * | 1985-11-22 | 1987-06-02 | Hitachi Ltd | 液浸対物レンズ装置 |
| JP2001091849A (ja) * | 1999-09-21 | 2001-04-06 | Olympus Optical Co Ltd | 顕微鏡用液浸対物レンズ |
| JP2002048978A (ja) * | 2000-08-01 | 2002-02-15 | Olympus Optical Co Ltd | 対物レンズユニット、対物レンズユニットを有する光学装置及びその光学装置を用いた観察方法 |
| JP2005079589A (ja) * | 2003-08-29 | 2005-03-24 | Asml Netherlands Bv | リソグラフィック装置及びデバイス製造方法 |
| JP2009505051A (ja) * | 2005-08-08 | 2009-02-05 | サントル ナシオナル ドゥ ラ ルシェルシェサイアンティフィク(セエヌエールエス) | 液浸干渉顕微鏡による断層イメージング |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6720547B1 (en) * | 1999-03-18 | 2004-04-13 | Lucid, Inc. | System and method for enhancing confocal reflectance images of tissue specimens |
| JP3797874B2 (ja) * | 2000-12-26 | 2006-07-19 | オリンパス株式会社 | 走査型光学顕微鏡 |
| DE10152609A1 (de) * | 2001-10-25 | 2003-05-08 | Max Planck Gesellschaft | Optisches Mikroskop mit verstellbarem Objektiv |
| DE20205080U1 (de) * | 2002-03-30 | 2002-06-13 | Leica Microsystems Heidelberg Gmbh, 68165 Mannheim | Immersionsobjektiv und Abschirmelement |
| JP2005189850A (ja) * | 2003-12-15 | 2005-07-14 | Carl Zeiss Smt Ag | 液浸リソグラフィー用屈折性投影対物レンズ |
| DE102004042913A1 (de) * | 2004-09-02 | 2006-03-30 | Westfälische-Wilhelms Universität Münster | Scanneranordnung und Verfahren zum optischen Abtasten eines Objektes |
-
2010
- 2010-02-12 DE DE102010007728A patent/DE102010007728A1/de not_active Ceased
-
2011
- 2011-02-11 WO PCT/EP2011/052031 patent/WO2011098557A1/de not_active Ceased
- 2011-02-11 US US13/578,608 patent/US20130044370A1/en not_active Abandoned
- 2011-02-11 JP JP2012552408A patent/JP2013519909A/ja active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS62121417A (ja) * | 1985-11-22 | 1987-06-02 | Hitachi Ltd | 液浸対物レンズ装置 |
| JP2001091849A (ja) * | 1999-09-21 | 2001-04-06 | Olympus Optical Co Ltd | 顕微鏡用液浸対物レンズ |
| JP2002048978A (ja) * | 2000-08-01 | 2002-02-15 | Olympus Optical Co Ltd | 対物レンズユニット、対物レンズユニットを有する光学装置及びその光学装置を用いた観察方法 |
| JP2005079589A (ja) * | 2003-08-29 | 2005-03-24 | Asml Netherlands Bv | リソグラフィック装置及びデバイス製造方法 |
| JP2009505051A (ja) * | 2005-08-08 | 2009-02-05 | サントル ナシオナル ドゥ ラ ルシェルシェサイアンティフィク(セエヌエールエス) | 液浸干渉顕微鏡による断層イメージング |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2022071821A (ja) * | 2020-10-28 | 2022-05-16 | オリンパス株式会社 | 光信号検出装置、ゲル部材、光信号検出方法 |
| JP7772525B2 (ja) | 2020-10-28 | 2025-11-18 | 株式会社エビデント | 光信号検出装置、ゲル部材、光信号検出方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2011098557A1 (de) | 2011-08-18 |
| DE102010007728A1 (de) | 2011-09-29 |
| US20130044370A1 (en) | 2013-02-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2013519909A (ja) | 対象物を走査する装置とその方法および顕微鏡 | |
| JP5779597B2 (ja) | 顕微鏡の構造ユニット、顕微鏡装置及び顕微鏡の構造ユニットの使用 | |
| CN101868320B (zh) | 激光束加工 | |
| JP7021190B2 (ja) | ライトシート顕微鏡 | |
| JP6209329B2 (ja) | 顕微鏡照明系および方法 | |
| JP7109423B2 (ja) | ライトシート顕微鏡 | |
| US10031326B2 (en) | System and method of edge-illumination microscopy | |
| US9229207B2 (en) | Laser scanning microscope with focus-detecting unit | |
| CN106461926A (zh) | 具有简化的光学器件、尤其是具有可变的光瞳位置的光扫描显微镜 | |
| JP2011118264A (ja) | 顕微鏡装置 | |
| CN103954598B (zh) | 一种基于倏逝波照明的轴向高精度定位方法及装置 | |
| JP2019537748A (ja) | 三次元画像化可能な顕微鏡及び画像化方法 | |
| WO2010055363A1 (en) | Laser scanning microscope | |
| US7551351B2 (en) | Microscope with evanescent sample illumination | |
| US10025081B2 (en) | Microscope for evanescent illumination and point-shaped raster illumination | |
| JPWO2009142312A1 (ja) | 顕微鏡装置 | |
| US20110255157A1 (en) | Microscope apparatus | |
| JP4172212B2 (ja) | 顕微鏡標本の照明方法とこれを用いた照明装置を有する顕微鏡 | |
| JP5039307B2 (ja) | 対物レンズおよび顕微鏡 | |
| JP4370404B2 (ja) | Dlp式エバネッセンス顕微鏡 | |
| US12320966B2 (en) | Method and system for multi-view episcopic selective plane illumination microscope | |
| CN117233947A (zh) | 显微镜照明系统、控制方法及显微成像检测系统 | |
| JP2021515910A (ja) | 大型試料を走査するための光学装置、光学モジュールおよび顕微鏡 | |
| JP5726656B2 (ja) | ディスク走査型共焦点観察装置 | |
| KR102677920B1 (ko) | 현미경 시스템 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20140128 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20140128 |
|
| A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20140702 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20140722 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20141021 |
|
| A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20141028 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20141121 |
|
| A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20141201 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20141219 |
|
| A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20150324 |