JP2013510900A - 炎症性疾患治療のための大環状ラクトン誘導体の使用 - Google Patents

炎症性疾患治療のための大環状ラクトン誘導体の使用 Download PDF

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JP2013510900A
JP2013510900A JP2012539451A JP2012539451A JP2013510900A JP 2013510900 A JP2013510900 A JP 2013510900A JP 2012539451 A JP2012539451 A JP 2012539451A JP 2012539451 A JP2012539451 A JP 2012539451A JP 2013510900 A JP2013510900 A JP 2013510900A
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alkyl
hydroxy
formula
compound
disease
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JP2013510900A5 (enExample
Inventor
アシャ クルカルニ−アルメイダ
ラヴィンドラ ダッタトラヤ グプテ
ニレシュ マドゥカル ダギア
プラバ ビアーチャンドラ ミシュラ
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Piramal Life Sciences Ltd
Piramal Enterprises Ltd
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Nicholas Piramal India Ltd
Piramal Life Sciences Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
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    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Neurology (AREA)
  • Dermatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Transplantation (AREA)
  • Reproductive Health (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
JP2012539451A 2009-11-17 2010-11-15 炎症性疾患治療のための大環状ラクトン誘導体の使用 Pending JP2013510900A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US26181009P 2009-11-17 2009-11-17
US61/261,810 2009-11-17
PCT/IB2010/055162 WO2011061667A1 (en) 2009-11-17 2010-11-15 Use of macrocyclic lactone derivatives for the treatment of inflammatory disorders

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JP2013510900A true JP2013510900A (ja) 2013-03-28
JP2013510900A5 JP2013510900A5 (enExample) 2014-01-09

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JP2012539451A Pending JP2013510900A (ja) 2009-11-17 2010-11-15 炎症性疾患治療のための大環状ラクトン誘導体の使用

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US (1) US20120225889A1 (enExample)
EP (1) EP2501378A1 (enExample)
JP (1) JP2013510900A (enExample)
AU (1) AU2010320558A1 (enExample)
CA (1) CA2780912A1 (enExample)
IL (1) IL219806A0 (enExample)
NZ (1) NZ600662A (enExample)
WO (1) WO2011061667A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013510899A (ja) * 2009-11-17 2013-03-28 ピラマル・ライフ・サイエンシーズ・リミテッド 癌治療のための大環状ラクトン誘導体
JP2021504397A (ja) * 2017-11-30 2021-02-15 ソシエテ・デ・プロデュイ・ネスレ・エス・アー 神経疾患の予防及び治療に使用するためのポリケチド化合物及びその誘導体

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9284283B2 (en) 2012-02-02 2016-03-15 Ensemble Therapeutics Corporation Macrocyclic compounds for modulating IL-17
WO2014118740A1 (en) * 2013-02-04 2014-08-07 Piramal Enterprises Limited Macrocyclic lactone derivatives and uses thereof
DE102017003725A1 (de) 2017-04-18 2018-10-18 Olaf Weber Anti-VEGF- und anti-C5-Antikörper zur Behandlung der equinen rezidivierenden Uveitis
CN116745276A (zh) * 2020-12-16 2023-09-12 密歇根大学董事会 Nef下调抑制剂

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07157433A (ja) * 1993-08-16 1995-06-20 Ciba Geigy Ag 新規のマクロライドを含んで成る医薬組成物
JPH08183733A (ja) * 1994-06-30 1996-07-16 Eli Lilly & Co β−アミロイドペプチドが関与する生理的障害を処置するための製剤
JP2013510899A (ja) * 2009-11-17 2013-03-28 ピラマル・ライフ・サイエンシーズ・リミテッド 癌治療のための大環状ラクトン誘導体

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070105791A1 (en) * 2002-07-29 2007-05-10 Optimer Pharmaceuticals, Inc. Method of treating clostridium difficile-associated diarrhea
EP1765312B1 (en) * 2004-05-14 2011-07-13 Optimer Pharmaceuticals, Inc. Treatment of diseases associated with the use of antibiotics
WO2009141786A2 (en) * 2008-05-21 2009-11-26 Piramal Life Sciences Limited Anti-inflammatory compounds

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07157433A (ja) * 1993-08-16 1995-06-20 Ciba Geigy Ag 新規のマクロライドを含んで成る医薬組成物
JPH08183733A (ja) * 1994-06-30 1996-07-16 Eli Lilly & Co β−アミロイドペプチドが関与する生理的障害を処置するための製剤
JP2013510899A (ja) * 2009-11-17 2013-03-28 ピラマル・ライフ・サイエンシーズ・リミテッド 癌治療のための大環状ラクトン誘導体

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JPN5013000497; HARUYASU KINASHI: 'ALKALINE DEGRADATION PRODUCTS OF CONCANAMYCIN A' TETRAHEDRON LETTERS V22 N39, 1981, P3857-3860 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013510899A (ja) * 2009-11-17 2013-03-28 ピラマル・ライフ・サイエンシーズ・リミテッド 癌治療のための大環状ラクトン誘導体
JP2021504397A (ja) * 2017-11-30 2021-02-15 ソシエテ・デ・プロデュイ・ネスレ・エス・アー 神経疾患の予防及び治療に使用するためのポリケチド化合物及びその誘導体
JP7359358B2 (ja) 2017-11-30 2023-10-11 グリアファーム エスエー 神経疾患の予防及び治療に使用するためのポリケチド化合物及びその誘導体

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AU2010320558A1 (en) 2012-07-12
EP2501378A1 (en) 2012-09-26
WO2011061667A1 (en) 2011-05-26
CA2780912A1 (en) 2011-05-26
IL219806A0 (en) 2012-07-31
US20120225889A1 (en) 2012-09-06
NZ600662A (en) 2014-05-30

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