JP2013507327A5 - - Google Patents
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- Publication number
- JP2013507327A5 JP2013507327A5 JP2012532432A JP2012532432A JP2013507327A5 JP 2013507327 A5 JP2013507327 A5 JP 2013507327A5 JP 2012532432 A JP2012532432 A JP 2012532432A JP 2012532432 A JP2012532432 A JP 2012532432A JP 2013507327 A5 JP2013507327 A5 JP 2013507327A5
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- alkoxy
- alkylcarbonyloxy
- independently
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001875 compounds Chemical class 0.000 claims 44
- 125000003545 alkoxy group Chemical group 0.000 claims 25
- 125000005196 alkyl carbonyloxy group Chemical group 0.000 claims 20
- 150000003839 salts Chemical class 0.000 claims 12
- 206010028980 Neoplasm Diseases 0.000 claims 5
- 201000011510 cancer Diseases 0.000 claims 5
- -1 (E) -3- (3,4-dimethoxyphenyl) acryloyl Chemical group 0.000 claims 4
- UUEVFMOUBSLVJW-UHFFFAOYSA-N oxo-[[1-[2-[2-[2-[4-(oxoazaniumylmethylidene)pyridin-1-yl]ethoxy]ethoxy]ethyl]pyridin-4-ylidene]methyl]azanium;dibromide Chemical compound [Br-].[Br-].C1=CC(=C[NH+]=O)C=CN1CCOCCOCCN1C=CC(=C[NH+]=O)C=C1 UUEVFMOUBSLVJW-UHFFFAOYSA-N 0.000 claims 4
- 125000004448 alkyl carbonyl group Chemical group 0.000 claims 2
- NGSWKAQJJWESNS-ZZXKWVIFSA-N trans-4-coumaric acid Chemical compound OC(=O)\C=C\C1=CC=C(O)C=C1 NGSWKAQJJWESNS-ZZXKWVIFSA-N 0.000 claims 2
- 230000006907 apoptotic process Effects 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- WZXKPNYMUZGZIA-RMKNXTFCSA-N propyl (e)-3-(4-methoxyphenyl)prop-2-enoate Chemical compound CCCOC(=O)\C=C\C1=CC=C(OC)C=C1 WZXKPNYMUZGZIA-RMKNXTFCSA-N 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25028709P | 2009-10-09 | 2009-10-09 | |
| US61/250,287 | 2009-10-09 | ||
| PCT/CA2010/001613 WO2011041907A1 (en) | 2009-10-09 | 2010-10-08 | Derivatives of di(phenylpropanoid) glycerol for the treatment of cancer |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013507327A JP2013507327A (ja) | 2013-03-04 |
| JP2013507327A5 true JP2013507327A5 (https=) | 2013-11-21 |
| JP5529280B2 JP5529280B2 (ja) | 2014-06-25 |
Family
ID=43352967
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012532432A Expired - Fee Related JP5529280B2 (ja) | 2009-10-09 | 2010-10-08 | 癌治療用のジ（フェニルプロパノイド）・グリセロール誘導体 |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US9061993B2 (https=) |
| EP (1) | EP2486026B1 (https=) |
| JP (1) | JP5529280B2 (https=) |
| CN (1) | CN102264713A (https=) |
| BR (1) | BR112012008204A2 (https=) |
| CA (1) | CA2715662C (https=) |
| CY (1) | CY1123161T1 (https=) |
| DK (1) | DK2486026T3 (https=) |
| ES (1) | ES2810906T3 (https=) |
| HR (1) | HRP20201217T1 (https=) |
| HU (1) | HUE051549T2 (https=) |
| LT (1) | LT2486026T (https=) |
| MX (1) | MX360417B (https=) |
| MY (2) | MY160378A (https=) |
| PL (1) | PL2486026T3 (https=) |
| PT (1) | PT2486026T (https=) |
| RS (1) | RS60667B1 (https=) |
| SI (1) | SI2486026T1 (https=) |
| SM (1) | SMT202000428T1 (https=) |
| WO (1) | WO2011041907A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8907117B2 (en) * | 2011-09-08 | 2014-12-09 | Henry Lowe | Anti-tumor and anti-inflammatory dicinnamoyl-glycerol esters and their analogues |
| US9907786B2 (en) | 2014-10-21 | 2018-03-06 | Ions Pharmaceutical S.À R.L. | Therapeutic compositions containing harmine and isovanillin components, and methods of use thereof |
| US10092550B2 (en) | 2014-10-21 | 2018-10-09 | Ions Pharmaceutical S.À R.L. | Therapeutic compositions containing curcumin, harmine, and isovanillin components, and methods of use thereof |
| US20160106687A1 (en) | 2014-10-21 | 2016-04-21 | Life Plus, LLC | Human therapeutic agents |
| US12129265B2 (en) | 2020-07-21 | 2024-10-29 | Ankh Life Sciences Limited | Therapeutic agents and uses thereof |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3857873A (en) | 1974-02-11 | 1974-12-31 | Warner Lambert Co | 3-hydroxy-5-(3-(substituted-amino)-2-hydroxypropoxy)-benzyl alcohols |
| CH648753A5 (de) * | 1981-07-22 | 1985-04-15 | Givaudan & Cie Sa | Lichtschutzmittel. |
| CN1238333C (zh) * | 2003-06-18 | 2006-01-25 | 清华大学 | 药物化合物菠萝酰酯及其制备方法和用途 |
| US7713556B2 (en) | 2006-12-08 | 2010-05-11 | Henry Lowe | Anti-tumor and anti-inflammatory extracts of plant biomass and their uses |
| JP2010515685A (ja) * | 2007-01-08 | 2010-05-13 | アンドロサイエンス コーポレーション | （置換フェニル）−プロペナール部分を伴う化合物、その誘導体、生物学的活性およびその使用 |
| TWI383251B (zh) * | 2008-01-16 | 2013-01-21 | Eternal Chemical Co Ltd | 感光型聚醯亞胺 |
| KR101074149B1 (ko) * | 2009-04-15 | 2011-10-17 | 한밭대학교 산학협력단 | 신규 폴리페놀/폴리페놀 컨쥬게이트 화합물 및 그의 용도 |
| US8907117B2 (en) * | 2011-09-08 | 2014-12-09 | Henry Lowe | Anti-tumor and anti-inflammatory dicinnamoyl-glycerol esters and their analogues |
-
2010
- 2010-10-08 LT LTEP10821532.8T patent/LT2486026T/lt unknown
- 2010-10-08 DK DK10821532.8T patent/DK2486026T3/da active
- 2010-10-08 MY MYPI2012001601A patent/MY160378A/en unknown
- 2010-10-08 CA CA2715662A patent/CA2715662C/en active Active
- 2010-10-08 PL PL10821532T patent/PL2486026T3/pl unknown
- 2010-10-08 PT PT108215328T patent/PT2486026T/pt unknown
- 2010-10-08 BR BR112012008204A patent/BR112012008204A2/pt not_active Application Discontinuation
- 2010-10-08 HU HUE10821532A patent/HUE051549T2/hu unknown
- 2010-10-08 CN CN201080003781XA patent/CN102264713A/zh active Pending
- 2010-10-08 MX MX2012004160A patent/MX360417B/es active IP Right Grant
- 2010-10-08 MY MYPI2016000361A patent/MY187188A/en unknown
- 2010-10-08 RS RS20200931A patent/RS60667B1/sr unknown
- 2010-10-08 WO PCT/CA2010/001613 patent/WO2011041907A1/en not_active Ceased
- 2010-10-08 US US12/901,113 patent/US9061993B2/en active Active
- 2010-10-08 HR HRP20201217TT patent/HRP20201217T1/hr unknown
- 2010-10-08 ES ES10821532T patent/ES2810906T3/es active Active
- 2010-10-08 JP JP2012532432A patent/JP5529280B2/ja not_active Expired - Fee Related
- 2010-10-08 EP EP10821532.8A patent/EP2486026B1/en active Active
- 2010-10-08 SM SM20200428T patent/SMT202000428T1/it unknown
- 2010-10-08 SI SI201032026T patent/SI2486026T1/sl unknown
-
2015
- 2015-05-17 US US14/714,318 patent/US10052301B2/en active Active
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2020
- 2020-08-05 CY CY20201100724T patent/CY1123161T1/el unknown