RS60667B1 - Derivati di(fenilpropanoid)glicerola za lečenje kancera - Google Patents

Derivati di(fenilpropanoid)glicerola za lečenje kancera

Info

Publication number
RS60667B1
RS60667B1 RS20200931A RSP20200931A RS60667B1 RS 60667 B1 RS60667 B1 RS 60667B1 RS 20200931 A RS20200931 A RS 20200931A RS P20200931 A RSP20200931 A RS P20200931A RS 60667 B1 RS60667 B1 RS 60667B1
Authority
RS
Serbia
Prior art keywords
cancer
compound
cells
produce
compounds
Prior art date
Application number
RS20200931A
Other languages
English (en)
Serbian (sr)
Inventor
Alexander Macgregor
Original Assignee
Alexander Macgregor
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alexander Macgregor filed Critical Alexander Macgregor
Publication of RS60667B1 publication Critical patent/RS60667B1/sr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/732—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids of unsaturated hydroxy carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/734—Ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/16—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by esterified hydroxyl radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
RS20200931A 2009-10-09 2010-10-08 Derivati di(fenilpropanoid)glicerola za lečenje kancera RS60667B1 (sr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US25028709P 2009-10-09 2009-10-09
PCT/CA2010/001613 WO2011041907A1 (en) 2009-10-09 2010-10-08 Derivatives of di(phenylpropanoid) glycerol for the treatment of cancer
EP10821532.8A EP2486026B1 (en) 2009-10-09 2010-10-08 Derivatives of di(phenylpropanoid) glycerol for the treatment of cancer

Publications (1)

Publication Number Publication Date
RS60667B1 true RS60667B1 (sr) 2020-09-30

Family

ID=43352967

Family Applications (1)

Application Number Title Priority Date Filing Date
RS20200931A RS60667B1 (sr) 2009-10-09 2010-10-08 Derivati di(fenilpropanoid)glicerola za lečenje kancera

Country Status (20)

Country Link
US (2) US9061993B2 (https=)
EP (1) EP2486026B1 (https=)
JP (1) JP5529280B2 (https=)
CN (1) CN102264713A (https=)
BR (1) BR112012008204A2 (https=)
CA (1) CA2715662C (https=)
CY (1) CY1123161T1 (https=)
DK (1) DK2486026T3 (https=)
ES (1) ES2810906T3 (https=)
HR (1) HRP20201217T1 (https=)
HU (1) HUE051549T2 (https=)
LT (1) LT2486026T (https=)
MX (1) MX360417B (https=)
MY (2) MY160378A (https=)
PL (1) PL2486026T3 (https=)
PT (1) PT2486026T (https=)
RS (1) RS60667B1 (https=)
SI (1) SI2486026T1 (https=)
SM (1) SMT202000428T1 (https=)
WO (1) WO2011041907A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8907117B2 (en) * 2011-09-08 2014-12-09 Henry Lowe Anti-tumor and anti-inflammatory dicinnamoyl-glycerol esters and their analogues
US9907786B2 (en) 2014-10-21 2018-03-06 Ions Pharmaceutical S.À R.L. Therapeutic compositions containing harmine and isovanillin components, and methods of use thereof
US10092550B2 (en) 2014-10-21 2018-10-09 Ions Pharmaceutical S.À R.L. Therapeutic compositions containing curcumin, harmine, and isovanillin components, and methods of use thereof
US20160106687A1 (en) 2014-10-21 2016-04-21 Life Plus, LLC Human therapeutic agents
US12129265B2 (en) 2020-07-21 2024-10-29 Ankh Life Sciences Limited Therapeutic agents and uses thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3857873A (en) 1974-02-11 1974-12-31 Warner Lambert Co 3-hydroxy-5-(3-(substituted-amino)-2-hydroxypropoxy)-benzyl alcohols
CH648753A5 (de) * 1981-07-22 1985-04-15 Givaudan & Cie Sa Lichtschutzmittel.
CN1238333C (zh) * 2003-06-18 2006-01-25 清华大学 药物化合物菠萝酰酯及其制备方法和用途
US7713556B2 (en) 2006-12-08 2010-05-11 Henry Lowe Anti-tumor and anti-inflammatory extracts of plant biomass and their uses
JP2010515685A (ja) * 2007-01-08 2010-05-13 アンドロサイエンス コーポレーション （置換フェニル）−プロペナール部分を伴う化合物、その誘導体、生物学的活性およびその使用
TWI383251B (zh) * 2008-01-16 2013-01-21 Eternal Chemical Co Ltd 感光型聚醯亞胺
KR101074149B1 (ko) * 2009-04-15 2011-10-17 한밭대학교 산학협력단 신규 폴리페놀/폴리페놀 컨쥬게이트 화합물 및 그의 용도
US8907117B2 (en) * 2011-09-08 2014-12-09 Henry Lowe Anti-tumor and anti-inflammatory dicinnamoyl-glycerol esters and their analogues

Also Published As

Publication number Publication date
CY1123161T1 (el) 2021-10-29
ES2810906T3 (es) 2021-03-09
LT2486026T (lt) 2020-09-10
US10052301B2 (en) 2018-08-21
JP5529280B2 (ja) 2014-06-25
US9061993B2 (en) 2015-06-23
EP2486026B1 (en) 2020-06-24
EP2486026A4 (en) 2015-07-01
CA2715662C (en) 2013-05-07
MX360417B (es) 2018-10-25
SMT202000428T1 (it) 2020-09-10
WO2011041907A1 (en) 2011-04-14
JP2013507327A (ja) 2013-03-04
EP2486026A1 (en) 2012-08-15
HRP20201217T1 (hr) 2020-12-11
HUE051549T2 (hu) 2021-10-28
CN102264713A (zh) 2011-11-30
MY160378A (en) 2017-03-15
PT2486026T (pt) 2020-08-21
US20150246014A1 (en) 2015-09-03
PL2486026T3 (pl) 2020-11-02
CA2715662A1 (en) 2010-12-14
MX2012004160A (es) 2012-09-07
US20110086912A1 (en) 2011-04-14
DK2486026T3 (da) 2020-08-17
BR112012008204A2 (pt) 2017-07-18
MY187188A (en) 2021-09-09
SI2486026T1 (sl) 2020-10-30

Similar Documents

Publication Publication Date Title
CN101711231B (zh) 具有(取代苯基)-丙烯醛部分的化合物、它们的衍生物、生物活性及其用途
Liu et al. Antiproliferative properties of piperidinylchalcones
Cao et al. Synthesis and biological evaluation of novel pyranochalcone derivatives as a new class of microtubule stabilizing agents
Naz et al. 4-Oxycoumarinyl linked acetohydrazide Schiff bases as potent urease inhibitors
WO2005032559A1 (en) Nitric oxide donating derivatives for the treatment of cardiovascular disorders
US10052301B2 (en) Derivatives of propane diyl dicinnamate
Li et al. Discovery of oral-available resveratrol-caffeic acid based hybrids inhibiting acetylated and phosphorylated STAT3 protein
EP3118204A1 (en) O-phenyl chalcone compound and preparation method and use thereof
Lin et al. Synthesis of aryl dihydrothiazol acyl shikonin ester derivatives as anticancer agents through microtubule stabilization
Reddy et al. Bis-chalcone analogues as potent NO production inhibitors and as cytotoxic agents
Pang et al. The synthesis and evaluation of new butadiene derivatives as tubulin polymerization inhibitors
EP3252039B1 (en) Compound containing indoleacetic acid core structure and use thereof
JP2019523227A (ja) クルクミノイドの新規な誘導体およびその抗がん剤としての使用
Karimikia et al. Colchicine-like β-acetamidoketones as inhibitors of microtubule polymerization: Design, synthesis and biological evaluation of in vitro anticancer activity
Liu et al. Synthesis of a celastrol derivative as a cancer stem cell inhibitor through regulation of the STAT3 pathway for treatment of ovarian cancer
JP7672153B2 (ja) クロメン系化合物、それらの方法及び使用
TWI419687B (zh) 作用於微小管抗癌藥物２’,５’－ｄｉｍｅｔｈｏｘｙｃｈａｌｃｏｎｅ衍生物之合成與活性評估
CN101050179B (zh) 2,3,4,5-四取代的苯丙烯类衍生物及其制备方法和用途
CN117586210B (zh) 甲硫醚取代的2,3-二氢呋喃类衍生物及其制备方法和用途
HK1164842A (en) Derivatives of di(phenylpropanoid) glycerol for the treatment of cancer
US8633242B2 (en) Benzylidene indanones and processes for preparation and use thereof
Yong et al. Synthesis of 1, 1'-Ferrocene Diformates Bearing Isoxazole Moiety and Preliminarily Cytotoxicity to A549, HCT116 and MCF-7 Cell Lines
US20230130823A1 (en) Process for the production of antitumour pharmaceutical compositions using push-pull butadienes, compounds and uses thereof
Wang et al. Synthesis and Application of Hydroquinone with Heptadecatrienyl Side Chain for Inhibition of SARS-CoV-2
Nichols Aggie Digital Collections and Scholarshi p