BR112012008204A2 - derivados de di(fenilpropanoide)glicerol para o tratamento de câncer - Google Patents
derivados de di(fenilpropanoide)glicerol para o tratamento de câncerInfo
- Publication number
- BR112012008204A2 BR112012008204A2 BR112012008204A BR112012008204A BR112012008204A2 BR 112012008204 A2 BR112012008204 A2 BR 112012008204A2 BR 112012008204 A BR112012008204 A BR 112012008204A BR 112012008204 A BR112012008204 A BR 112012008204A BR 112012008204 A2 BR112012008204 A2 BR 112012008204A2
- Authority
- BR
- Brazil
- Prior art keywords
- phenylpropanoid
- cancer treatment
- glycerol derivatives
- glycerol
- derivatives
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- 150000002314 glycerols Chemical class 0.000 title 1
- 229930015704 phenylpropanoid Natural products 0.000 title 1
- 150000002995 phenylpropanoid derivatives Chemical class 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/732—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids of unsaturated hydroxy carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/734—Ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/16—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by esterified hydroxyl radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epoxy Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25028709P | 2009-10-09 | 2009-10-09 | |
| PCT/CA2010/001613 WO2011041907A1 (en) | 2009-10-09 | 2010-10-08 | Derivatives of di(phenylpropanoid) glycerol for the treatment of cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112012008204A2 true BR112012008204A2 (pt) | 2017-07-18 |
Family
ID=43352967
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112012008204A BR112012008204A2 (pt) | 2009-10-09 | 2010-10-08 | derivados de di(fenilpropanoide)glicerol para o tratamento de câncer |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US9061993B2 (https=) |
| EP (1) | EP2486026B1 (https=) |
| JP (1) | JP5529280B2 (https=) |
| CN (1) | CN102264713A (https=) |
| BR (1) | BR112012008204A2 (https=) |
| CA (1) | CA2715662C (https=) |
| CY (1) | CY1123161T1 (https=) |
| DK (1) | DK2486026T3 (https=) |
| ES (1) | ES2810906T3 (https=) |
| HR (1) | HRP20201217T1 (https=) |
| HU (1) | HUE051549T2 (https=) |
| LT (1) | LT2486026T (https=) |
| MX (1) | MX360417B (https=) |
| MY (2) | MY160378A (https=) |
| PL (1) | PL2486026T3 (https=) |
| PT (1) | PT2486026T (https=) |
| RS (1) | RS60667B1 (https=) |
| SI (1) | SI2486026T1 (https=) |
| SM (1) | SMT202000428T1 (https=) |
| WO (1) | WO2011041907A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8907117B2 (en) * | 2011-09-08 | 2014-12-09 | Henry Lowe | Anti-tumor and anti-inflammatory dicinnamoyl-glycerol esters and their analogues |
| US9907786B2 (en) | 2014-10-21 | 2018-03-06 | Ions Pharmaceutical S.À R.L. | Therapeutic compositions containing harmine and isovanillin components, and methods of use thereof |
| US10092550B2 (en) | 2014-10-21 | 2018-10-09 | Ions Pharmaceutical S.À R.L. | Therapeutic compositions containing curcumin, harmine, and isovanillin components, and methods of use thereof |
| US20160106687A1 (en) | 2014-10-21 | 2016-04-21 | Life Plus, LLC | Human therapeutic agents |
| US12129265B2 (en) | 2020-07-21 | 2024-10-29 | Ankh Life Sciences Limited | Therapeutic agents and uses thereof |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3857873A (en) | 1974-02-11 | 1974-12-31 | Warner Lambert Co | 3-hydroxy-5-(3-(substituted-amino)-2-hydroxypropoxy)-benzyl alcohols |
| CH648753A5 (de) * | 1981-07-22 | 1985-04-15 | Givaudan & Cie Sa | Lichtschutzmittel. |
| CN1238333C (zh) * | 2003-06-18 | 2006-01-25 | 清华大学 | 药物化合物菠萝酰酯及其制备方法和用途 |
| US7713556B2 (en) | 2006-12-08 | 2010-05-11 | Henry Lowe | Anti-tumor and anti-inflammatory extracts of plant biomass and their uses |
| JP2010515685A (ja) * | 2007-01-08 | 2010-05-13 | アンドロサイエンス コーポレーション | （置換フェニル）−プロペナール部分を伴う化合物、その誘導体、生物学的活性およびその使用 |
| TWI383251B (zh) * | 2008-01-16 | 2013-01-21 | Eternal Chemical Co Ltd | 感光型聚醯亞胺 |
| KR101074149B1 (ko) * | 2009-04-15 | 2011-10-17 | 한밭대학교 산학협력단 | 신규 폴리페놀/폴리페놀 컨쥬게이트 화합물 및 그의 용도 |
| US8907117B2 (en) * | 2011-09-08 | 2014-12-09 | Henry Lowe | Anti-tumor and anti-inflammatory dicinnamoyl-glycerol esters and their analogues |
-
2010
- 2010-10-08 LT LTEP10821532.8T patent/LT2486026T/lt unknown
- 2010-10-08 DK DK10821532.8T patent/DK2486026T3/da active
- 2010-10-08 MY MYPI2012001601A patent/MY160378A/en unknown
- 2010-10-08 CA CA2715662A patent/CA2715662C/en active Active
- 2010-10-08 PL PL10821532T patent/PL2486026T3/pl unknown
- 2010-10-08 PT PT108215328T patent/PT2486026T/pt unknown
- 2010-10-08 BR BR112012008204A patent/BR112012008204A2/pt not_active Application Discontinuation
- 2010-10-08 HU HUE10821532A patent/HUE051549T2/hu unknown
- 2010-10-08 CN CN201080003781XA patent/CN102264713A/zh active Pending
- 2010-10-08 MX MX2012004160A patent/MX360417B/es active IP Right Grant
- 2010-10-08 MY MYPI2016000361A patent/MY187188A/en unknown
- 2010-10-08 RS RS20200931A patent/RS60667B1/sr unknown
- 2010-10-08 WO PCT/CA2010/001613 patent/WO2011041907A1/en not_active Ceased
- 2010-10-08 US US12/901,113 patent/US9061993B2/en active Active
- 2010-10-08 HR HRP20201217TT patent/HRP20201217T1/hr unknown
- 2010-10-08 ES ES10821532T patent/ES2810906T3/es active Active
- 2010-10-08 JP JP2012532432A patent/JP5529280B2/ja not_active Expired - Fee Related
- 2010-10-08 EP EP10821532.8A patent/EP2486026B1/en active Active
- 2010-10-08 SM SM20200428T patent/SMT202000428T1/it unknown
- 2010-10-08 SI SI201032026T patent/SI2486026T1/sl unknown
-
2015
- 2015-05-17 US US14/714,318 patent/US10052301B2/en active Active
-
2020
- 2020-08-05 CY CY20201100724T patent/CY1123161T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CY1123161T1 (el) | 2021-10-29 |
| ES2810906T3 (es) | 2021-03-09 |
| LT2486026T (lt) | 2020-09-10 |
| US10052301B2 (en) | 2018-08-21 |
| JP5529280B2 (ja) | 2014-06-25 |
| US9061993B2 (en) | 2015-06-23 |
| EP2486026B1 (en) | 2020-06-24 |
| EP2486026A4 (en) | 2015-07-01 |
| CA2715662C (en) | 2013-05-07 |
| MX360417B (es) | 2018-10-25 |
| SMT202000428T1 (it) | 2020-09-10 |
| WO2011041907A1 (en) | 2011-04-14 |
| JP2013507327A (ja) | 2013-03-04 |
| EP2486026A1 (en) | 2012-08-15 |
| HRP20201217T1 (hr) | 2020-12-11 |
| HUE051549T2 (hu) | 2021-10-28 |
| CN102264713A (zh) | 2011-11-30 |
| MY160378A (en) | 2017-03-15 |
| PT2486026T (pt) | 2020-08-21 |
| US20150246014A1 (en) | 2015-09-03 |
| RS60667B1 (sr) | 2020-09-30 |
| PL2486026T3 (pl) | 2020-11-02 |
| CA2715662A1 (en) | 2010-12-14 |
| MX2012004160A (es) | 2012-09-07 |
| US20110086912A1 (en) | 2011-04-14 |
| DK2486026T3 (da) | 2020-08-17 |
| MY187188A (en) | 2021-09-09 |
| SI2486026T1 (sl) | 2020-10-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] | ||
| B08G | Application fees: restoration [chapter 8.7 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
| B06T | Formal requirements before examination [chapter 6.20 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL |