JP2013505983A5 - - Google Patents
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- Publication number
- JP2013505983A5 JP2013505983A5 JP2012532119A JP2012532119A JP2013505983A5 JP 2013505983 A5 JP2013505983 A5 JP 2013505983A5 JP 2012532119 A JP2012532119 A JP 2012532119A JP 2012532119 A JP2012532119 A JP 2012532119A JP 2013505983 A5 JP2013505983 A5 JP 2013505983A5
- Authority
- JP
- Japan
- Prior art keywords
- agonist
- patient
- receptor modulator
- medicament according
- monitoring
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000003814 drug Substances 0.000 claims 39
- 239000000556 agonist Substances 0.000 claims 30
- 102000011011 Sphingosine 1-phosphate receptors Human genes 0.000 claims 29
- 108050001083 Sphingosine 1-phosphate receptors Proteins 0.000 claims 29
- 229940075993 receptor modulator Drugs 0.000 claims 28
- 229940044601 receptor agonist Drugs 0.000 claims 26
- 238000012544 monitoring process Methods 0.000 claims 18
- 238000000034 method Methods 0.000 claims 17
- 229940079593 drug Drugs 0.000 claims 12
- SWZTYAVBMYWFGS-UHFFFAOYSA-N fingolimod hydrochloride Chemical compound Cl.CCCCCCCCC1=CC=C(CCC(N)(CO)CO)C=C1 SWZTYAVBMYWFGS-UHFFFAOYSA-N 0.000 claims 12
- 229960000556 fingolimod Drugs 0.000 claims 11
- 125000002467 phosphate group Chemical class [H]OP(=O)(O[H])O[*] 0.000 claims 8
- 150000003839 salts Chemical class 0.000 claims 8
- 208000015181 infectious disease Diseases 0.000 claims 6
- 206010061217 Infestation Diseases 0.000 claims 4
- 201000006417 multiple sclerosis Diseases 0.000 claims 4
- 229960005475 antiinfective agent Drugs 0.000 claims 3
- 239000004599 antimicrobial Substances 0.000 claims 3
- 208000006218 bradycardia Diseases 0.000 claims 3
- 238000007449 liver function test Methods 0.000 claims 3
- 208000023275 Autoimmune disease Diseases 0.000 claims 2
- 102000004190 Enzymes Human genes 0.000 claims 2
- 108090000790 Enzymes Proteins 0.000 claims 2
- 208000001344 Macular Edema Diseases 0.000 claims 2
- 206010025415 Macular oedema Diseases 0.000 claims 2
- 208000000453 Skin Neoplasms Diseases 0.000 claims 2
- 239000002246 antineoplastic agent Substances 0.000 claims 2
- 230000036471 bradycardia Effects 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 208000027866 inflammatory disease Diseases 0.000 claims 2
- 230000002757 inflammatory effect Effects 0.000 claims 2
- 210000004185 liver Anatomy 0.000 claims 2
- 238000013123 lung function test Methods 0.000 claims 2
- 201000010230 macular retinal edema Diseases 0.000 claims 2
- 230000004048 modification Effects 0.000 claims 2
- 238000012986 modification Methods 0.000 claims 2
- 201000000849 skin cancer Diseases 0.000 claims 2
- 208000024891 symptom Diseases 0.000 claims 2
- 230000004304 visual acuity Effects 0.000 claims 2
- 206010003671 Atrioventricular Block Diseases 0.000 claims 1
- 206010049765 Bradyarrhythmia Diseases 0.000 claims 1
- 206010020772 Hypertension Diseases 0.000 claims 1
- 208000007400 Relapsing-Remitting Multiple Sclerosis Diseases 0.000 claims 1
- 230000005856 abnormality Effects 0.000 claims 1
- 230000002411 adverse Effects 0.000 claims 1
- 229940030600 antihypertensive agent Drugs 0.000 claims 1
- 239000002220 antihypertensive agent Substances 0.000 claims 1
- 239000002876 beta blocker Substances 0.000 claims 1
- 229940097320 beta blocking agent Drugs 0.000 claims 1
- 238000004159 blood analysis Methods 0.000 claims 1
- 230000036772 blood pressure Effects 0.000 claims 1
- 238000001647 drug administration Methods 0.000 claims 1
- 230000004064 dysfunction Effects 0.000 claims 1
- 230000008030 elimination Effects 0.000 claims 1
- 238000003379 elimination reaction Methods 0.000 claims 1
- 208000030533 eye disease Diseases 0.000 claims 1
- 230000004438 eyesight Effects 0.000 claims 1
- 230000000977 initiatory effect Effects 0.000 claims 1
- 230000003908 liver function Effects 0.000 claims 1
- 238000009613 pulmonary function test Methods 0.000 claims 1
- 230000004202 respiratory function Effects 0.000 claims 1
- 230000000284 resting effect Effects 0.000 claims 1
- 208000017520 skin disease Diseases 0.000 claims 1
- 238000002255 vaccination Methods 0.000 claims 1
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24670609P | 2009-09-29 | 2009-09-29 | |
| US61/246,706 | 2009-09-29 | ||
| US25832909P | 2009-11-05 | 2009-11-05 | |
| US61/258,329 | 2009-11-05 | ||
| US30799210P | 2010-02-25 | 2010-02-25 | |
| US61/307,992 | 2010-02-25 | ||
| US35202910P | 2010-06-07 | 2010-06-07 | |
| US61/352,029 | 2010-06-07 | ||
| PCT/US2010/049441 WO2011041146A2 (en) | 2009-09-29 | 2010-09-20 | Dosage regimen of an s1p receptor modulator |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016061356A Division JP2016155840A (ja) | 2009-09-29 | 2016-03-25 | Ｓ１ｐ受容体モジュレーターの投与計画 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013505983A JP2013505983A (ja) | 2013-02-21 |
| JP2013505983A5 true JP2013505983A5 (enExample) | 2013-10-31 |
Family
ID=43759693
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012532119A Withdrawn JP2013505983A (ja) | 2009-09-29 | 2010-09-20 | Ｓ１ｐ受容体モジュレーターの投与計画 |
| JP2016061356A Withdrawn JP2016155840A (ja) | 2009-09-29 | 2016-03-25 | Ｓ１ｐ受容体モジュレーターの投与計画 |
| JP2018116214A Active JP7185426B2 (ja) | 2009-09-29 | 2018-06-19 | Ｓ１ｐ受容体モジュレーターの投与計画 |
| JP2020133934A Pending JP2020203892A (ja) | 2009-09-29 | 2020-08-06 | Ｓ１ｐ受容体モジュレーターの投与計画 |
| JP2023052843A Pending JP2023093482A (ja) | 2009-09-29 | 2023-03-29 | Ｓ１ｐ受容体モジュレーターの投与計画 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016061356A Withdrawn JP2016155840A (ja) | 2009-09-29 | 2016-03-25 | Ｓ１ｐ受容体モジュレーターの投与計画 |
| JP2018116214A Active JP7185426B2 (ja) | 2009-09-29 | 2018-06-19 | Ｓ１ｐ受容体モジュレーターの投与計画 |
| JP2020133934A Pending JP2020203892A (ja) | 2009-09-29 | 2020-08-06 | Ｓ１ｐ受容体モジュレーターの投与計画 |
| JP2023052843A Pending JP2023093482A (ja) | 2009-09-29 | 2023-03-29 | Ｓ１ｐ受容体モジュレーターの投与計画 |
Country Status (18)
| Country | Link |
|---|---|
| US (8) | US20120264719A1 (enExample) |
| EP (4) | EP2482810A2 (enExample) |
| JP (5) | JP2013505983A (enExample) |
| KR (1) | KR20120083442A (enExample) |
| CN (2) | CN103933570A (enExample) |
| AU (2) | AU2010101513B4 (enExample) |
| BR (1) | BR112012006957A2 (enExample) |
| CA (2) | CA2773330C (enExample) |
| IL (2) | IL218486A0 (enExample) |
| MA (1) | MA33691B1 (enExample) |
| MX (1) | MX2012003740A (enExample) |
| NZ (1) | NZ598534A (enExample) |
| PH (2) | PH12012500520A1 (enExample) |
| RU (1) | RU2012117563A (enExample) |
| SG (4) | SG10201902152XA (enExample) |
| TN (1) | TN2012000104A1 (enExample) |
| WO (1) | WO2011041146A2 (enExample) |
| ZA (2) | ZA201201678B (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20120264719A1 (en) * | 2009-09-29 | 2012-10-18 | Craig Boulton | Dosage regimen of an s1p receptor modulator |
| US20110124605A1 (en) * | 2009-11-20 | 2011-05-26 | Shreeram Aradhye | Use of an S1P Receptor Agonist |
| BR112013017302B1 (pt) | 2011-01-07 | 2021-12-07 | Novartis Ag | Composição farmacêutica em fase sólida |
| JP6133790B2 (ja) | 2011-02-18 | 2017-05-24 | ザ スクリプス リサーチ インスティテュート | ミエリン形成細胞運命へのオリゴデンドロサイト前駆細胞の定方向分化 |
| EP2766020A4 (en) * | 2011-10-12 | 2015-04-01 | Teva Pharma | TREATMENT OF MULTIPLE SCLEROSIS BY COMBINING LAQUINIMOD AND FINGOLIMOD |
| MX2014004813A (es) * | 2011-10-21 | 2014-05-20 | Novartis Ag | Regimen de dosificacion para un modulador o agonista del receptor s1p. |
| EP3199947A3 (en) * | 2013-04-04 | 2017-09-13 | Novartis AG | Identifying patient response to s1p receptor modulator administration |
| US20170027907A1 (en) * | 2014-04-10 | 2017-02-02 | Eric Legangneux | Sip modulator immediate release dosage regimen |
| US20180042895A1 (en) | 2015-02-26 | 2018-02-15 | Novartis Ag | Treatment of autoimmune disease in a patient receiving additionally a beta-blocker |
| CN116784795A (zh) | 2017-11-30 | 2023-09-22 | 思维有限公司 | 用于评估与多发性硬化症相关的神经功能受损的方法 |
| SG11202111417UA (en) * | 2019-04-17 | 2021-11-29 | Pear Therapeutics Inc | Electronic devices and methods for treatment of depressive symptoms, depressive disorders utilizing digital therapies |
| WO2021158847A1 (en) * | 2020-02-07 | 2021-08-12 | Argentum Pharmaceuticals Llc | Treatment and dosing regimen for s1p receptor modulator |
| WO2021158839A1 (en) * | 2020-02-07 | 2021-08-12 | Argentum Pharmaceuticals Llc | Treatment and dosing regimen for s1p receptor modulator |
| WO2021158843A1 (en) * | 2020-02-07 | 2021-08-12 | Argentum Pharmaceuticals Llc | Treatment and dosing regimen for s1p receptor modulator |
| US11135197B2 (en) | 2020-02-07 | 2021-10-05 | Argentum Pharmaceuticals Llc | Dosage regimen of an S1P receptor modulator |
| WO2021158845A1 (en) * | 2020-02-07 | 2021-08-12 | Argentum Pharmaceuticals Llc | Treatment and dosing regimen for s1p receptor modulator |
| WO2021158844A1 (en) * | 2020-02-07 | 2021-08-12 | Argentum Pharmaceuticals Llc | Treatment and dosing regimen for s1p receptor modulator |
| WO2021158841A1 (en) * | 2020-02-07 | 2021-08-12 | Argentum Pharmaceuticals Llc | Treatment and dosing regimen for s1p receptor modulator |
| JP2023530681A (ja) * | 2020-06-11 | 2023-07-19 | ザ・トラスティーズ・オブ・コロンビア・ユニバーシティ・イン・ザ・シティ・オブ・ニューヨーク | フィンゴリモド、スフィンゴシン－１－リン酸受容体修飾薬、及びその誘導体を用いて近視を予防及び治療するための方法及び組成物 |
| JP2025526449A (ja) * | 2022-07-28 | 2025-08-13 | ヴューマインド インコーポレイテッド | 特定の薬品又は治療が視覚処理、認知機能、及び関連する脳の活動を向上させるであろう、特定の視覚的刺激を使用する際の眼球運動パターンを分析する、定義された疾病を有する被験者の特定の変化を識別する方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6231560B1 (en) * | 1999-02-10 | 2001-05-15 | Baxter International Inc | Method and apparatus for automatically controlling the level of medication |
| GB0211261D0 (en) * | 2002-05-16 | 2002-06-26 | Novartis Ag | Organic compounds |
| ES2316758T3 (es) | 2002-05-16 | 2009-04-16 | Novartis Ag | Uso de aglutinantes del receptor edg en el cancer. |
| CA2518385A1 (en) * | 2003-03-14 | 2004-09-23 | Agi Therapeutics Ltd. | Treatment of intestinal conditions with n-2,3,3-tetramethylbicyclo[2.2.1]heptan-2-amine |
| JP4728962B2 (ja) | 2003-05-19 | 2011-07-20 | アイアールエム・リミテッド・ライアビリティ・カンパニー | 免疫抑制化合物および組成物 |
| EP1663188B1 (en) | 2003-09-12 | 2016-08-10 | Newron Sweden AB | Treatment of disorders of the nervous system |
| US7127355B2 (en) * | 2004-03-05 | 2006-10-24 | Perlegen Sciences, Inc. | Methods for genetic analysis |
| KR20130041385A (ko) * | 2004-11-29 | 2013-04-24 | 노파르티스 아게 | Ｓ１ｐ 수용체 효능제의 투여 용법 |
| JP2007061274A (ja) * | 2005-08-30 | 2007-03-15 | Transcutaneous Technologies Inc | センサからの副作用情報による投薬停止システムを備えたイオントフォレーシス装置 |
| EP1923058A1 (en) * | 2006-09-26 | 2008-05-21 | Novartis AG | Coated pharmaceutical composition comprising an S1P agonist or modulator |
| EP1905434A1 (en) | 2006-09-26 | 2008-04-02 | Novartis AG | Organic compounds comprising an S1P receptor agonist and their therapeutic use |
| SG10201406263SA (en) | 2008-06-20 | 2015-02-27 | Novartis Ag | Paediatric compositions for treating multiple sclerosis |
| HRP20151190T1 (hr) | 2008-12-22 | 2016-01-01 | Novartis Ag | Režim doziranja za fingolimod u lijeäśenju multiple skleroze |
| US20120264719A1 (en) * | 2009-09-29 | 2012-10-18 | Craig Boulton | Dosage regimen of an s1p receptor modulator |
-
2010
- 2010-09-20 US US13/497,349 patent/US20120264719A1/en not_active Abandoned
- 2010-09-20 EP EP10759777A patent/EP2482810A2/en not_active Withdrawn
- 2010-09-20 EP EP15188591.0A patent/EP3061449A1/en not_active Withdrawn
- 2010-09-20 PH PH1/2012/500520A patent/PH12012500520A1/en unknown
- 2010-09-20 AU AU2010101513A patent/AU2010101513B4/en not_active Expired
- 2010-09-20 EP EP21151843.6A patent/EP3831371A1/en not_active Ceased
- 2010-09-20 SG SG10201902152XA patent/SG10201902152XA/en unknown
- 2010-09-20 CA CA2773330A patent/CA2773330C/en active Active
- 2010-09-20 SG SG2012015368A patent/SG178987A1/en unknown
- 2010-09-20 CA CA3129729A patent/CA3129729A1/en not_active Abandoned
- 2010-09-20 JP JP2012532119A patent/JP2013505983A/ja not_active Withdrawn
- 2010-09-20 NZ NZ598534A patent/NZ598534A/en unknown
- 2010-09-20 WO PCT/US2010/049441 patent/WO2011041146A2/en not_active Ceased
- 2010-09-20 KR KR1020127010834A patent/KR20120083442A/ko not_active Ceased
- 2010-09-20 BR BR112012006957A patent/BR112012006957A2/pt not_active IP Right Cessation
- 2010-09-20 RU RU2012117563/15A patent/RU2012117563A/ru unknown
- 2010-09-20 SG SG10201406168RA patent/SG10201406168RA/en unknown
- 2010-09-20 SG SG10201913361RA patent/SG10201913361RA/en unknown
- 2010-09-20 EP EP15186346.1A patent/EP3047848A1/en not_active Ceased
- 2010-09-20 CN CN201410184034.0A patent/CN103933570A/zh active Pending
- 2010-09-20 MX MX2012003740A patent/MX2012003740A/es not_active Application Discontinuation
- 2010-09-20 AU AU2010300919A patent/AU2010300919A1/en active Pending
- 2010-09-20 CN CN2010800434886A patent/CN102548579A/zh active Pending
-
2012
- 2012-03-05 IL IL218486A patent/IL218486A0/en unknown
- 2012-03-06 TN TNP2012000104A patent/TN2012000104A1/en unknown
- 2012-03-07 ZA ZA2012/01678A patent/ZA201201678B/en unknown
- 2012-04-26 MA MA34805A patent/MA33691B1/fr unknown
-
2014
- 2014-02-10 US US14/176,504 patent/US20140187516A1/en not_active Abandoned
- 2014-06-09 ZA ZA2014/04270A patent/ZA201404270B/en unknown
-
2016
- 2016-03-25 JP JP2016061356A patent/JP2016155840A/ja not_active Withdrawn
- 2016-05-12 US US15/152,894 patent/US20160256416A1/en not_active Abandoned
-
2017
- 2017-02-05 IL IL250439A patent/IL250439A0/en unknown
- 2017-07-11 US US15/646,583 patent/US20170304226A1/en not_active Abandoned
- 2017-08-17 PH PH12017501495A patent/PH12017501495A1/en unknown
-
2018
- 2018-05-23 US US15/986,992 patent/US10543179B2/en active Active
- 2018-05-23 US US15/987,011 patent/US20180263930A1/en not_active Abandoned
- 2018-06-19 JP JP2018116214A patent/JP7185426B2/ja active Active
-
2020
- 2020-01-10 US US16/739,403 patent/US11759436B2/en active Active
- 2020-08-06 JP JP2020133934A patent/JP2020203892A/ja active Pending
-
2022
- 2022-04-28 US US17/731,920 patent/US20230086687A1/en not_active Abandoned
-
2023
- 2023-03-29 JP JP2023052843A patent/JP2023093482A/ja active Pending
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