JP2013503819A5 - - Google Patents
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- Publication number
- JP2013503819A5 JP2013503819A5 JP2012526118A JP2012526118A JP2013503819A5 JP 2013503819 A5 JP2013503819 A5 JP 2013503819A5 JP 2012526118 A JP2012526118 A JP 2012526118A JP 2012526118 A JP2012526118 A JP 2012526118A JP 2013503819 A5 JP2013503819 A5 JP 2013503819A5
- Authority
- JP
- Japan
- Prior art keywords
- independently
- olr
- compound according
- compound
- saturated aliphatic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- GYNOMWDIFUXJBS-UHFFFAOYSA-N CC(C)Oc(cc(cc1C(F)(F)F)C(Nc(cc2)ccc2C(O)=O)=O)c1OC(C)C Chemical compound CC(C)Oc(cc(cc1C(F)(F)F)C(Nc(cc2)ccc2C(O)=O)=O)c1OC(C)C GYNOMWDIFUXJBS-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0915196.0A GB0915196D0 (en) | 2009-09-01 | 2009-09-01 | Therapeutic compounds and their use |
| GB0915196.0 | 2009-09-01 | ||
| PCT/GB2010/001650 WO2011027106A1 (en) | 2009-09-01 | 2010-09-01 | Therapeutic aryl-am i do-aryl compounds and their use |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013503819A JP2013503819A (ja) | 2013-02-04 |
| JP2013503819A5 true JP2013503819A5 (https=) | 2013-08-22 |
| JP5778675B2 JP5778675B2 (ja) | 2015-09-16 |
Family
ID=41202973
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012526118A Expired - Fee Related JP5778675B2 (ja) | 2009-09-01 | 2010-09-01 | 治療性アリール−アミド−アリール化合物およびその使用 |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US20120149737A1 (https=) |
| EP (1) | EP2473479A1 (https=) |
| JP (1) | JP5778675B2 (https=) |
| CN (1) | CN102639487A (https=) |
| AU (1) | AU2010291056B2 (https=) |
| BR (1) | BR112012004173A2 (https=) |
| CA (1) | CA2771097C (https=) |
| GB (1) | GB0915196D0 (https=) |
| IL (1) | IL218137A (https=) |
| MX (1) | MX2012002481A (https=) |
| NZ (1) | NZ598331A (https=) |
| RU (1) | RU2012108173A (https=) |
| SG (1) | SG178480A1 (https=) |
| WO (1) | WO2011027106A1 (https=) |
| ZA (1) | ZA201201287B (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0915196D0 (en) | 2009-09-01 | 2009-10-07 | King S College London | Therapeutic compounds and their use |
| WO2012125749A2 (en) * | 2011-03-14 | 2012-09-20 | Io Therapeutics, Inc. | INFLAMMATION AND AUTOIMMUNE DISORDER TREATMENT USING RARα SELECTIVE AGONISTS |
| CN102727475B (zh) * | 2012-06-14 | 2014-05-07 | 合肥博太医药生物技术发展有限公司 | 视黄酸及其衍生物在制备防治老年痴呆药物中的应用 |
| JP6596090B2 (ja) * | 2014-12-17 | 2019-10-23 | キングス カレッジ ロンドン | レチノイン酸受容体ベータ（ＲＡＲβ）アゴニストとしてのビシクロヘテロアリール−ヘテロアリール−安息香酸化合物 |
| EP3267969A1 (en) * | 2015-03-09 | 2018-01-17 | King's College London | Combination therapy with rar alpha agonists for enhancing th1 response |
| WO2017066428A1 (en) | 2015-10-13 | 2017-04-20 | H. Lee Moffitt Cancer Center & Research Institute, Inc. | Brd4-kinase inhibitors as cancer therapeutics |
| WO2017174999A1 (en) * | 2016-04-07 | 2017-10-12 | High Force Research Limited | Synthetic retinoids for use in rar mediated conditions |
| CN107459519A (zh) | 2016-06-06 | 2017-12-12 | 上海艾力斯医药科技有限公司 | 稠合嘧啶哌啶环衍生物及其制备方法和应用 |
| GB201900687D0 (en) | 2019-01-17 | 2019-03-06 | King S College London | Immunotherapeutic methods and compositions |
| AU2019400930A1 (en) | 2018-12-19 | 2021-07-01 | King's College London | Immunotherapeutic methods and compositions |
| CA3128032A1 (en) | 2019-01-29 | 2020-08-06 | The Johns Hopkins University | Small molecule neutral sphingomyelinase 2 (nsmase2) inhibitors |
| WO2020263960A1 (en) * | 2019-06-28 | 2020-12-30 | Carl Wagner | Compositions comprising a retinoid x receptor (rxr) agonist, a retinoic acid receptor (rar) agonist, or a dual rxr/rar agonist |
| JP2026500298A (ja) | 2022-12-15 | 2026-01-06 | シンジェンタ クロップ プロテクション アクチェンゲゼルシャフト | 殺有害生物剤として有用である新規な二環式カルボキサミド化合物 |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2260118C2 (de) | 1972-12-08 | 1982-06-03 | Bayer Ag, 5090 Leverkusen | Penicilline sowie ihre Verwendung als Arzneimittel |
| DE3580134D1 (de) | 1984-07-07 | 1990-11-22 | Shudo Koichi Prof Dr Chem | Benzoesaeurederivate. |
| JPS61233678A (ja) | 1985-04-09 | 1986-10-17 | Maruko Seiyaku Kk | ベンジルピペラジン誘導体 |
| JPS62215581A (ja) | 1986-03-18 | 1987-09-22 | Koichi Shiyudo | フラボンカルボン酸誘導体 |
| US4808631A (en) | 1986-11-07 | 1989-02-28 | Hoffmann-La Roche Inc. | Aromatic acid derivatives |
| US4992468A (en) | 1989-07-26 | 1991-02-12 | Allergan, Inc. | Phenylethenyl compounds having retinoid-like activity |
| ZA911101B (en) * | 1990-02-14 | 1991-11-27 | Chugai Pharmaceutical Co Ltd | Inhibition of modified ldl products |
| FR2663850B1 (fr) | 1990-07-02 | 1994-01-14 | Gird Galderma | Composition pharmaceutique ou cosmetique contenant en association un retinouide et un sterol. |
| EP0619116A3 (en) | 1993-04-05 | 1994-11-23 | Hoechst Japan | Use of synthetic retinoids for osteopathy. |
| US5648385A (en) | 1994-01-03 | 1997-07-15 | Bristol-Myers Squibb Co. | Retinoid-like compounds |
| US5849735A (en) | 1995-01-17 | 1998-12-15 | American Cyanamid Company | Tricyclic benzazepine vasopressin antagonists |
| US5559248A (en) | 1995-04-05 | 1996-09-24 | Bristol-Myers Squibb Co. | Retinoid-like heterocycles |
| ES2180751T3 (es) | 1995-04-10 | 2003-02-16 | Taiho Pharmaceutical Co Ltd | Inhibidor de metastasis de cancer. |
| JP3964478B2 (ja) | 1995-06-30 | 2007-08-22 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | ヘテロ環含有カルボン酸誘導体及びそれを含有する医薬 |
| FR2739777B1 (fr) | 1995-10-11 | 1997-11-14 | Cird Galderma | Ligand antagoniste rar-gamma ou agoniste rar-alpha en tant qu'inhibiteur d'apoptose |
| US5663357A (en) * | 1995-11-22 | 1997-09-02 | Allergan | Substituted heteroarylamides having retinoid-like biological activity |
| HUP0102470A3 (en) | 1998-07-01 | 2002-05-28 | Takeda Chemical Industries Ltd | 1,3-azole derivatives as retinoid-associated receptor regulators and their use |
| US6245884B1 (en) | 1998-10-16 | 2001-06-12 | Vivian Y. H. Hook | Secretases related to alzheimer's dementia |
| PL198852B1 (pl) | 1998-10-22 | 2008-07-31 | Neurosearch As | Podstawione pochodne fenylu, kompozycja farmaceutyczna je zawierająca oraz ich zastosowanie |
| TW400614B (en) | 1998-11-06 | 2000-08-01 | United Microelectronics Corp | The manufacture method of Shallow Trench Isolation(STI) |
| US6897304B2 (en) | 2000-09-22 | 2005-05-24 | Zenyaku Kogyo Kabushiki Kaisha | Cephem compounds and ESBL-detecting reagents containing the same |
| CA2432825A1 (en) | 2000-12-15 | 2002-06-20 | Emory University | Nonpeptide agonists and antagonists of vasopressin receptors |
| GB0103998D0 (en) | 2001-02-19 | 2001-04-04 | King S College London | Method |
| US7105566B2 (en) * | 2002-10-22 | 2006-09-12 | Allergan, Inc. | Methods of treatment during vascular procedures |
| US8367822B2 (en) | 2003-09-22 | 2013-02-05 | Enzo Therapeutics, Inc. | Compositions and methods for bone formation and remodeling |
| KR100921173B1 (ko) * | 2007-11-14 | 2009-10-13 | (주)아모레퍼시픽 | 피부 내에서 히알루론산 생합성을 촉진시키는3,4,5-트리메톡시벤즈 아미드 유도체 화합물, 그 제조방법및 이를 함유하는 화장료 조성물 |
| EP2415755A4 (en) | 2009-03-31 | 2012-09-19 | Renascience Co Ltd | INHIBITOR AGENT OF PLASMINOGEN ACTIVATOR INHIBITOR 1 |
| GB0915196D0 (en) | 2009-09-01 | 2009-10-07 | King S College London | Therapeutic compounds and their use |
| WO2012058378A1 (en) | 2010-10-29 | 2012-05-03 | Romark Laboratories L.C. | Pharmaceutical compositions and methods of use of salicylanilides for treatment of hepatitis viruses |
-
2009
- 2009-09-01 GB GBGB0915196.0A patent/GB0915196D0/en not_active Ceased
-
2010
- 2010-09-01 AU AU2010291056A patent/AU2010291056B2/en not_active Ceased
- 2010-09-01 CA CA2771097A patent/CA2771097C/en not_active Expired - Fee Related
- 2010-09-01 EP EP10752907A patent/EP2473479A1/en not_active Withdrawn
- 2010-09-01 JP JP2012526118A patent/JP5778675B2/ja not_active Expired - Fee Related
- 2010-09-01 NZ NZ598331A patent/NZ598331A/xx not_active IP Right Cessation
- 2010-09-01 RU RU2012108173/04A patent/RU2012108173A/ru not_active Application Discontinuation
- 2010-09-01 MX MX2012002481A patent/MX2012002481A/es not_active Application Discontinuation
- 2010-09-01 WO PCT/GB2010/001650 patent/WO2011027106A1/en not_active Ceased
- 2010-09-01 US US13/391,207 patent/US20120149737A1/en not_active Abandoned
- 2010-09-01 CN CN2010800493386A patent/CN102639487A/zh active Pending
- 2010-09-01 SG SG2012011193A patent/SG178480A1/en unknown
- 2010-09-01 BR BR112012004173A patent/BR112012004173A2/pt not_active IP Right Cessation
-
2012
- 2012-02-16 IL IL218137A patent/IL218137A/en active IP Right Grant
- 2012-02-21 ZA ZA2012/01287A patent/ZA201201287B/en unknown
-
2015
- 2015-10-09 US US14/879,340 patent/US9447028B2/en not_active Expired - Fee Related
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