JP2013503742A - ジャンクションを使用して生成された多重エマルジョン - Google Patents

ジャンクションを使用して生成された多重エマルジョン Download PDF

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Publication number
JP2013503742A
JP2013503742A JP2012527993A JP2012527993A JP2013503742A JP 2013503742 A JP2013503742 A JP 2013503742A JP 2012527993 A JP2012527993 A JP 2012527993A JP 2012527993 A JP2012527993 A JP 2012527993A JP 2013503742 A JP2013503742 A JP 2013503742A
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JP
Japan
Prior art keywords
fluid
channel
channels
sol
hydrophilic
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Pending
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JP2012527993A
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English (en)
Japanese (ja)
Inventor
デイビッド エー． ウェイツ，
マーク ロマノフスキー，
クリスティアン ホルツェ，
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Harvard University
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Harvard University
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Publication of JP2013503742A publication Critical patent/JP2013503742A/ja
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/40—Mixing liquids with liquids; Emulsifying
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/40—Mixing liquids with liquids; Emulsifying
    • B01F23/41—Emulsifying
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B01F33/3035—Micromixers using surface tension to mix, move or hold the fluids
    • B01F33/30351—Micromixers using surface tension to mix, move or hold the fluids using hydrophilic/hydrophobic surfaces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/80—Forming a predetermined ratio of the substances to be mixed
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/40—Mixing liquids with liquids; Emulsifying
    • B01F23/41—Emulsifying
    • B01F23/414—Emulsifying characterised by the internal structure of the emulsion
    • B01F23/4144—Multiple emulsions, in particular double emulsions, e.g. water in oil in water; Three-phase emulsions
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/0318—Processes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/8593—Systems
    • Y10T137/87571—Multiple inlet with single outlet

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  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Colloid Chemistry (AREA)
JP2012527993A 2009-09-02 2010-09-01 ジャンクションを使用して生成された多重エマルジョン Pending JP2013503742A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23940209P 2009-09-02 2009-09-02
US61/239,402 2009-09-02
PCT/US2010/047458 WO2011028760A2 (en) 2009-09-02 2010-09-01 Multiple emulsions created using junctions

Publications (1)

Publication Number Publication Date
JP2013503742A true JP2013503742A (ja) 2013-02-04

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Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012527993A Pending JP2013503742A (ja) 2009-09-02 2010-09-01 ジャンクションを使用して生成された多重エマルジョン

Country Status (8)

Country Link
US (1) US20120199226A1 (enExample)
EP (1) EP2473262A4 (enExample)
JP (1) JP2013503742A (enExample)
KR (1) KR20120089662A (enExample)
CN (1) CN102481529A (enExample)
BR (1) BR112012004715A2 (enExample)
IN (1) IN2012DN01972A (enExample)
WO (1) WO2011028760A2 (enExample)

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EP1861194A2 (en) 2005-03-04 2007-12-05 The President and Fellows of Harvard College Method and apparatus for forming multiple emulsions
WO2010033200A2 (en) 2008-09-19 2010-03-25 President And Fellows Of Harvard College Creation of libraries of droplets and related species
US9399215B2 (en) 2012-04-13 2016-07-26 Bio-Rad Laboratories, Inc. Sample holder with a well having a wicking promoter
US20140024023A1 (en) * 2012-07-23 2014-01-23 Bio- Rad Laboratories, Inc Droplet generation system with features for sample positioning
GB2471522B (en) * 2009-07-03 2014-01-08 Cambridge Entpr Ltd Microfluidic devices
EP2473263B1 (en) 2009-09-02 2022-11-02 President and Fellows of Harvard College Multiple emulsions created using jetting and other techniques
KR101243147B1 (ko) 2011-03-15 2013-03-13 충남대학교산학협력단 미세유체 칩 채널의 선택적 표면개질방법 및 이를 이용한 멀티플 이멀전 제조용 미세유체 칩의 제조방법
WO2012162296A2 (en) 2011-05-23 2012-11-29 President And Fellows Of Harvard College Control of emulsions, including multiple emulsions
WO2013006661A2 (en) 2011-07-06 2013-01-10 President And Fellows Of Harvard College Multiple emulsions and techniques for the formation of multiple emulsions
EP2750787A2 (en) 2011-08-30 2014-07-09 President and Fellows of Harvard College Systems and methods for shell encapsulation
CN102553504B (zh) * 2012-01-18 2014-12-17 朗盛（常州）有限公司 一种乳液制备方法及皮革护理乳液、其用途
US9403294B2 (en) 2013-04-17 2016-08-02 Bio-Rad Laboratories, Inc. Method of making a droplet-generating device
EP3065712A4 (en) 2013-11-08 2017-06-21 President and Fellows of Harvard College Microparticles, methods for their preparation and use
WO2015160919A1 (en) 2014-04-16 2015-10-22 President And Fellows Of Harvard College Systems and methods for producing droplet emulsions with relatively thin shells
EP3223935A1 (en) 2014-11-24 2017-10-04 The Procter and Gamble Company Systems for encapsulation of actives within droplets and other compartments
CA3001679A1 (en) 2015-10-13 2017-04-20 President And Fellows Of Harvard College Systems and methods for making and using gel microspheres
CN106492716B (zh) * 2016-12-20 2024-01-30 中国工程物理研究院激光聚变研究中心 一体式双重乳粒发生装置及其加工方法
EP4435113B1 (en) 2017-05-18 2025-12-10 10X Genomics, Inc. Methods and systems for sorting droplets and beads
US10544413B2 (en) 2017-05-18 2020-01-28 10X Genomics, Inc. Methods and systems for sorting droplets and beads
US10821442B2 (en) 2017-08-22 2020-11-03 10X Genomics, Inc. Devices, systems, and kits for forming droplets
WO2019083852A1 (en) 2017-10-26 2019-05-02 10X Genomics, Inc. MICROFLUIDIC CHANNEL NETWORKS FOR PARTITIONING
US20190321791A1 (en) * 2018-04-19 2019-10-24 President And Fellows Of Harvard College Apparatus and method for forming emulsions
WO2020157262A1 (en) * 2019-01-31 2020-08-06 Samplix Aps A microfluidic device and a method for provision of double emulsion droplets

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JP2004351417A (ja) * 2001-02-23 2004-12-16 Japan Science & Technology Agency エマルションの製造装置
JP2005144356A (ja) * 2003-11-17 2005-06-09 Tosoh Corp 微小流路構造体及びこれを用いた微小粒子製造方法
JP2005152773A (ja) * 2003-11-25 2005-06-16 Tosoh Corp 微小流路による粒子製造方法
JP2005152740A (ja) * 2003-11-25 2005-06-16 National Food Research Institute エマルションの製造方法および製造装置
WO2005089921A1 (ja) * 2004-03-23 2005-09-29 Japan Science And Technology Agency 微小液滴の生成方法及び装置
US20090012187A1 (en) * 2007-03-28 2009-01-08 President And Fellows Of Harvard College Emulsions and Techniques for Formation
WO2009048532A2 (en) * 2007-10-05 2009-04-16 President And Fellows Of Harvard College Formation of particles for ultrasound application, drug release, and other uses, and microfluidic methods of preparation

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JP2004202476A (ja) * 2002-11-06 2004-07-22 Tosoh Corp 粒子製造方法及びそのための微小流路構造体
JP2005144356A (ja) * 2003-11-17 2005-06-09 Tosoh Corp 微小流路構造体及びこれを用いた微小粒子製造方法
JP2005152773A (ja) * 2003-11-25 2005-06-16 Tosoh Corp 微小流路による粒子製造方法
JP2005152740A (ja) * 2003-11-25 2005-06-16 National Food Research Institute エマルションの製造方法および製造装置
WO2005089921A1 (ja) * 2004-03-23 2005-09-29 Japan Science And Technology Agency 微小液滴の生成方法及び装置
US20090012187A1 (en) * 2007-03-28 2009-01-08 President And Fellows Of Harvard College Emulsions and Techniques for Formation
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2022107898A1 (enExample) * 2020-11-20 2022-05-27
WO2022107898A1 (ja) * 2020-11-20 2022-05-27 国立大学法人東京工業大学 マイクロ二相液滴生成デバイス

Also Published As

Publication number Publication date
KR20120089662A (ko) 2012-08-13
US20120199226A1 (en) 2012-08-09
BR112012004715A2 (pt) 2017-05-23
WO2011028760A2 (en) 2011-03-10
IN2012DN01972A (enExample) 2015-08-21
EP2473262A2 (en) 2012-07-11
CN102481529A (zh) 2012-05-30
EP2473262A4 (en) 2015-12-02
WO2011028760A3 (en) 2011-07-14

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