CN102481529A - 使用交汇产生的多重乳液 - Google Patents

使用交汇产生的多重乳液 Download PDF

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Publication number
CN102481529A
CN102481529A CN2010800390182A CN201080039018A CN102481529A CN 102481529 A CN102481529 A CN 102481529A CN 2010800390182 A CN2010800390182 A CN 2010800390182A CN 201080039018 A CN201080039018 A CN 201080039018A CN 102481529 A CN102481529 A CN 102481529A
Authority
CN
China
Prior art keywords
fluid
conduit
fluid conduit
hydrophilic
hydrophobic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN2010800390182A
Other languages
English (en)
Chinese (zh)
Inventor
D·A·韦茨
M·罗曼诺威斯基
C·霍尔茨
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Harvard University
Original Assignee
BASF SE
Harvard University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BASF SE, Harvard University filed Critical BASF SE
Publication of CN102481529A publication Critical patent/CN102481529A/zh
Pending legal-status Critical Current

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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B01F33/3035—Micromixers using surface tension to mix, move or hold the fluids
    • B01F33/30351—Micromixers using surface tension to mix, move or hold the fluids using hydrophilic/hydrophobic surfaces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/40—Mixing liquids with liquids; Emulsifying
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/40—Mixing liquids with liquids; Emulsifying
    • B01F23/41—Emulsifying
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/80—Forming a predetermined ratio of the substances to be mixed
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/40—Mixing liquids with liquids; Emulsifying
    • B01F23/41—Emulsifying
    • B01F23/414—Emulsifying characterised by the internal structure of the emulsion
    • B01F23/4144—Multiple emulsions, in particular double emulsions, e.g. water in oil in water; Three-phase emulsions
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/0318—Processes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/8593—Systems
    • Y10T137/87571—Multiple inlet with single outlet

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  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Colloid Chemistry (AREA)
CN2010800390182A 2009-09-02 2010-09-01 使用交汇产生的多重乳液 Pending CN102481529A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23940209P 2009-09-02 2009-09-02
US61/239,402 2009-09-02
PCT/US2010/047458 WO2011028760A2 (en) 2009-09-02 2010-09-01 Multiple emulsions created using junctions

Publications (1)

Publication Number Publication Date
CN102481529A true CN102481529A (zh) 2012-05-30

Family

ID=43649932

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2010800390182A Pending CN102481529A (zh) 2009-09-02 2010-09-01 使用交汇产生的多重乳液

Country Status (8)

Country Link
US (1) US20120199226A1 (enExample)
EP (1) EP2473262A4 (enExample)
JP (1) JP2013503742A (enExample)
KR (1) KR20120089662A (enExample)
CN (1) CN102481529A (enExample)
BR (1) BR112012004715A2 (enExample)
IN (1) IN2012DN01972A (enExample)
WO (1) WO2011028760A2 (enExample)

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US9399215B2 (en) 2012-04-13 2016-07-26 Bio-Rad Laboratories, Inc. Sample holder with a well having a wicking promoter
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GB2471522B (en) * 2009-07-03 2014-01-08 Cambridge Entpr Ltd Microfluidic devices
EP2473263B1 (en) 2009-09-02 2022-11-02 President and Fellows of Harvard College Multiple emulsions created using jetting and other techniques
KR101243147B1 (ko) 2011-03-15 2013-03-13 충남대학교산학협력단 미세유체 칩 채널의 선택적 표면개질방법 및 이를 이용한 멀티플 이멀전 제조용 미세유체 칩의 제조방법
WO2012162296A2 (en) 2011-05-23 2012-11-29 President And Fellows Of Harvard College Control of emulsions, including multiple emulsions
WO2013006661A2 (en) 2011-07-06 2013-01-10 President And Fellows Of Harvard College Multiple emulsions and techniques for the formation of multiple emulsions
EP2750787A2 (en) 2011-08-30 2014-07-09 President and Fellows of Harvard College Systems and methods for shell encapsulation
CN102553504B (zh) * 2012-01-18 2014-12-17 朗盛（常州）有限公司 一种乳液制备方法及皮革护理乳液、其用途
US9403294B2 (en) 2013-04-17 2016-08-02 Bio-Rad Laboratories, Inc. Method of making a droplet-generating device
EP3065712A4 (en) 2013-11-08 2017-06-21 President and Fellows of Harvard College Microparticles, methods for their preparation and use
WO2015160919A1 (en) 2014-04-16 2015-10-22 President And Fellows Of Harvard College Systems and methods for producing droplet emulsions with relatively thin shells
EP3223935A1 (en) 2014-11-24 2017-10-04 The Procter and Gamble Company Systems for encapsulation of actives within droplets and other compartments
CA3001679A1 (en) 2015-10-13 2017-04-20 President And Fellows Of Harvard College Systems and methods for making and using gel microspheres
CN106492716B (zh) * 2016-12-20 2024-01-30 中国工程物理研究院激光聚变研究中心 一体式双重乳粒发生装置及其加工方法
EP4435113B1 (en) 2017-05-18 2025-12-10 10X Genomics, Inc. Methods and systems for sorting droplets and beads
US10544413B2 (en) 2017-05-18 2020-01-28 10X Genomics, Inc. Methods and systems for sorting droplets and beads
US10821442B2 (en) 2017-08-22 2020-11-03 10X Genomics, Inc. Devices, systems, and kits for forming droplets
WO2019083852A1 (en) 2017-10-26 2019-05-02 10X Genomics, Inc. MICROFLUIDIC CHANNEL NETWORKS FOR PARTITIONING
US20190321791A1 (en) * 2018-04-19 2019-10-24 President And Fellows Of Harvard College Apparatus and method for forming emulsions
WO2020157262A1 (en) * 2019-01-31 2020-08-06 Samplix Aps A microfluidic device and a method for provision of double emulsion droplets
WO2022107898A1 (ja) * 2020-11-20 2022-05-27 国立大学法人東京工業大学 マイクロ二相液滴生成デバイス

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CN1695809A (zh) * 2004-05-10 2005-11-16 富士施乐株式会社 用于输送微粒分散液的方法及用于输送微粒分散液的装置

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Also Published As

Publication number Publication date
KR20120089662A (ko) 2012-08-13
JP2013503742A (ja) 2013-02-04
US20120199226A1 (en) 2012-08-09
BR112012004715A2 (pt) 2017-05-23
WO2011028760A2 (en) 2011-03-10
IN2012DN01972A (enExample) 2015-08-21
EP2473262A2 (en) 2012-07-11
EP2473262A4 (en) 2015-12-02
WO2011028760A3 (en) 2011-07-14

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Application publication date: 20120530