IN2012DN01972A - - Google Patents

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Publication number
IN2012DN01972A
IN2012DN01972A IN1972DEN2012A IN2012DN01972A IN 2012DN01972 A IN2012DN01972 A IN 2012DN01972A IN 1972DEN2012 A IN1972DEN2012 A IN 1972DEN2012A IN 2012DN01972 A IN2012DN01972 A IN 2012DN01972A
Authority
IN
India
Prior art keywords
hydrophilic
hydrophobic
emulsions
common intersection
channels
Prior art date
Application number
Other languages
English (en)
Inventor
David A Weitz
Mark Romanowsky
Christian Holtze
Original Assignee
Harvard College
Basf Se
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Harvard College, Basf Se filed Critical Harvard College
Publication of IN2012DN01972A publication Critical patent/IN2012DN01972A/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B01F33/3035—Micromixers using surface tension to mix, move or hold the fluids
    • B01F33/30351—Micromixers using surface tension to mix, move or hold the fluids using hydrophilic/hydrophobic surfaces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/40—Mixing liquids with liquids; Emulsifying
    • B01F23/41—Emulsifying
    • B01F23/414—Emulsifying characterised by the internal structure of the emulsion
    • B01F23/4144—Multiple emulsions, in particular double emulsions, e.g. water in oil in water; Three-phase emulsions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/40—Mixing liquids with liquids; Emulsifying
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/40—Mixing liquids with liquids; Emulsifying
    • B01F23/41—Emulsifying
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/80—Forming a predetermined ratio of the substances to be mixed
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/0318—Processes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T137/00—Fluid handling
    • Y10T137/8593—Systems
    • Y10T137/87571—Multiple inlet with single outlet

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Colloid Chemistry (AREA)
IN1972DEN2012 2009-09-02 2010-09-01 IN2012DN01972A (enExample)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23940209P 2009-09-02 2009-09-02
PCT/US2010/047458 WO2011028760A2 (en) 2009-09-02 2010-09-01 Multiple emulsions created using junctions

Publications (1)

Publication Number Publication Date
IN2012DN01972A true IN2012DN01972A (enExample) 2015-08-21

Family

ID=43649932

Family Applications (1)

Application Number Title Priority Date Filing Date
IN1972DEN2012 IN2012DN01972A (enExample) 2009-09-02 2010-09-01

Country Status (8)

Country Link
US (1) US20120199226A1 (enExample)
EP (1) EP2473262A4 (enExample)
JP (1) JP2013503742A (enExample)
KR (1) KR20120089662A (enExample)
CN (1) CN102481529A (enExample)
BR (1) BR112012004715A2 (enExample)
IN (1) IN2012DN01972A (enExample)
WO (1) WO2011028760A2 (enExample)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9039273B2 (en) 2005-03-04 2015-05-26 President And Fellows Of Harvard College Method and apparatus for forming multiple emulsions
US20110218123A1 (en) 2008-09-19 2011-09-08 President And Fellows Of Harvard College Creation of libraries of droplets and related species
GB2471522B (en) * 2009-07-03 2014-01-08 Cambridge Entpr Ltd Microfluidic devices
WO2011028764A2 (en) 2009-09-02 2011-03-10 President And Fellows Of Harvard College Multiple emulsions created using jetting and other techniques
KR101243147B1 (ko) 2011-03-15 2013-03-13 충남대학교산학협력단 미세유체 칩 채널의 선택적 표면개질방법 및 이를 이용한 멀티플 이멀전 제조용 미세유체 칩의 제조방법
JP6122843B2 (ja) 2011-05-23 2017-04-26 プレジデント アンド フェローズ オブ ハーバード カレッジ 多重エマルジョンを含むエマルジョンの制御
US20140220350A1 (en) 2011-07-06 2014-08-07 President And Fellows Of Harvard College Multiple emulsions and techniques for the formation of multiple emulsions
CN103764272A (zh) 2011-08-30 2014-04-30 哈佛学院院长等 壳包囊的体系和方法
CN102553504B (zh) * 2012-01-18 2014-12-17 朗盛（常州）有限公司 一种乳液制备方法及皮革护理乳液、其用途
WO2013155531A2 (en) * 2012-04-13 2013-10-17 Bio-Rad Laboratories, Inc. Sample holder with a well having a wicking promoter
WO2014018562A1 (en) * 2012-07-23 2014-01-30 Bio-Rad Laboratories, Inc. Droplet generation system with features for sample positioning
US9403294B2 (en) 2013-04-17 2016-08-02 Bio-Rad Laboratories, Inc. Method of making a droplet-generating device
WO2015069634A1 (en) 2013-11-08 2015-05-14 President And Fellows Of Harvard College Microparticles, methods for their preparation and use
WO2015160919A1 (en) 2014-04-16 2015-10-22 President And Fellows Of Harvard College Systems and methods for producing droplet emulsions with relatively thin shells
WO2016085743A1 (en) 2014-11-24 2016-06-02 President And Fellows Of Harvard College Methods and systems for encapsulation of actives within droplets and other compartments
EP3362032A4 (en) 2015-10-13 2019-05-01 President and Fellows of Harvard College SYSTEMS AND METHOD FOR THE PRODUCTION AND USE OF GEL MICROBALLETS
CN106492716B (zh) * 2016-12-20 2024-01-30 中国工程物理研究院激光聚变研究中心 一体式双重乳粒发生装置及其加工方法
US10544413B2 (en) 2017-05-18 2020-01-28 10X Genomics, Inc. Methods and systems for sorting droplets and beads
EP4215616B1 (en) 2017-05-18 2024-09-04 10X Genomics, Inc. Methods and systems for sorting droplets and beads
US10357771B2 (en) 2017-08-22 2019-07-23 10X Genomics, Inc. Method of producing emulsions
WO2019083852A1 (en) 2017-10-26 2019-05-02 10X Genomics, Inc. MICROFLUIDIC CHANNEL NETWORKS FOR PARTITIONING
US20190321791A1 (en) * 2018-04-19 2019-10-24 President And Fellows Of Harvard College Apparatus and method for forming emulsions
CN113710352B (zh) 2019-01-31 2024-03-26 赛普公司 微流体装置和用于提供双乳液液滴的方法
WO2022107898A1 (ja) * 2020-11-20 2022-05-27 国立大学法人東京工業大学 マイクロ二相液滴生成デバイス

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59131355A (ja) * 1983-01-17 1984-07-28 森下仁丹株式会社 多重軟カプセルの製法
US6623788B1 (en) * 2000-07-25 2003-09-23 Seagate Technology Llc Defect-free patterning of sol-gel-coated substrates for magnetic recording media
JP3860186B2 (ja) * 2001-02-23 2006-12-20 独立行政法人科学技術振興機構 エマルションの製造装置
DE60211857T2 (de) * 2001-02-23 2006-12-21 Japan Science And Technology Agency, Kawaguchi Verfahren zur herstellung einer emulsion und vorrichtung dafür
JP4186637B2 (ja) * 2002-11-06 2008-11-26 東ソー株式会社 粒子製造方法及びそのための微小流路構造体
US7595195B2 (en) * 2003-02-11 2009-09-29 The Regents Of The University Of California Microfluidic devices for controlled viscous shearing and formation of amphiphilic vesicles
EP1611407A2 (de) * 2003-03-31 2006-01-04 Behr GmbH & Co. Wärmetauscher und verfahren zur oberflächenbehandlung eines solchen
JP4341372B2 (ja) * 2003-10-30 2009-10-07 コニカミノルタホールディングス株式会社 液体の混合方法および混合装置ならびに混合システム
JP4042683B2 (ja) * 2003-11-17 2008-02-06 東ソー株式会社 微小流路構造体及びこれを用いた微小粒子製造方法
JP4305145B2 (ja) * 2003-11-25 2009-07-29 東ソー株式会社 微小流路による粒子製造方法
JP3777427B2 (ja) * 2003-11-25 2006-05-24 独立行政法人食品総合研究所 エマルションの製造方法および製造装置
EP1757357B1 (en) * 2004-03-23 2013-04-24 Japan Science and Technology Agency Method and device for producing micro-droplets
JP4461900B2 (ja) * 2004-05-10 2010-05-12 富士ゼロックス株式会社 微粒子分散液の送液方法、及び微粒子分散液の送液装置
US20070047388A1 (en) * 2005-08-25 2007-03-01 Rockwell Scientific Licensing, Llc Fluidic mixing structure, method for fabricating same, and mixing method
EP2136786B8 (en) * 2007-03-28 2012-11-14 President and Fellows of Harvard College Apparatus for forming droplets
WO2009048532A2 (en) * 2007-10-05 2009-04-16 President And Fellows Of Harvard College Formation of particles for ultrasound application, drug release, and other uses, and microfluidic methods of preparation
US9011777B2 (en) * 2008-03-21 2015-04-21 Lawrence Livermore National Security, Llc Monodisperse microdroplet generation and stopping without coalescence
EP2271581A4 (en) * 2008-03-28 2014-09-03 Harvard College MICROFLUID CHANNELS CONTAINING SURFACES WITH CONTROLLED WETTING CHARACTERISTICS
KR101132732B1 (ko) * 2008-11-26 2012-04-06 한국과학기술연구원 인 시튜 조직재생용 지능형 다공성 생분해 고분자 지지체 및 이의 제조방법
US9446360B2 (en) * 2009-05-07 2016-09-20 Universite De Strasbourg Microfluidic system and methods for highly selective droplet fusion
GB2471522B (en) * 2009-07-03 2014-01-08 Cambridge Entpr Ltd Microfluidic devices

Also Published As

Publication number Publication date
EP2473262A4 (en) 2015-12-02
WO2011028760A2 (en) 2011-03-10
US20120199226A1 (en) 2012-08-09
JP2013503742A (ja) 2013-02-04
WO2011028760A3 (en) 2011-07-14
CN102481529A (zh) 2012-05-30
EP2473262A2 (en) 2012-07-11
KR20120089662A (ko) 2012-08-13
BR112012004715A2 (pt) 2017-05-23

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