JP2013503178A - タンパク質キナーゼ調節物質としての縮合キノリン - Google Patents
タンパク質キナーゼ調節物質としての縮合キノリン Download PDFInfo
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Landscapes
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23722709P | 2009-08-26 | 2009-08-26 | |
| US61/237,227 | 2009-08-26 | ||
| US28931709P | 2009-12-22 | 2009-12-22 | |
| US61/289,317 | 2009-12-22 | ||
| PCT/US2010/046760 WO2011025859A1 (en) | 2009-08-26 | 2010-08-26 | Condensed quinolines as protein kinase modulators |
Publications (1)
| Publication Number | Publication Date |
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| JP2013503178A true JP2013503178A (ja) | 2013-01-31 |
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| JP2012526972A Pending JP2013503178A (ja) | 2009-08-26 | 2010-08-26 | タンパク質キナーゼ調節物質としての縮合キノリン |
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| EP (1) | EP2470544A1 (enExample) |
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| CA (1) | CA2771890A1 (enExample) |
| IL (1) | IL218280A0 (enExample) |
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| EP2943485B1 (en) | 2013-01-14 | 2017-09-20 | Incyte Holdings Corporation | Bicyclic aromatic carboxamide compounds useful as pim kinase inhibitors |
| AU2014207691B2 (en) | 2013-01-15 | 2018-08-30 | Incyte Holdings Corporation | Thiazolecarboxamides and pyridinecarboxamide compounds useful as Pim kinase inhibitors |
| EP3036238A1 (en) | 2013-08-23 | 2016-06-29 | Incyte Corporation | Furo- and thieno-pyridine carboxamide compounds useful as pim kinase inhibitors |
| US9580418B2 (en) | 2014-07-14 | 2017-02-28 | Incyte Corporation | Bicyclic aromatic carboxamide compounds useful as Pim kinase inhibitors |
| US9822124B2 (en) | 2014-07-14 | 2017-11-21 | Incyte Corporation | Bicyclic heteroaromatic carboxamide compounds useful as Pim kinase inhibitors |
| US9540347B2 (en) | 2015-05-29 | 2017-01-10 | Incyte Corporation | Pyridineamine compounds useful as Pim kinase inhibitors |
| TWI734699B (zh) | 2015-09-09 | 2021-08-01 | 美商英塞特公司 | Ｐｉｍ激酶抑制劑之鹽 |
| WO2017059251A1 (en) | 2015-10-02 | 2017-04-06 | Incyte Corporation | Heterocyclic compounds useful as pim kinase inhibitors |
| CN111031799A (zh) * | 2017-07-03 | 2020-04-17 | 拜耳作物科学股份公司 | 新的取代的异噻唑并吡啶酮、其制备方法及其用作除草剂和/或植物生长调节剂的用途 |
| TW201924683A (zh) | 2017-12-08 | 2019-07-01 | 美商英塞特公司 | 用於治療骨髓增生性贅瘤的低劑量組合療法 |
| US11071727B2 (en) | 2018-01-26 | 2021-07-27 | Northwestern University | Therapeutic targeting of proteolytic cleavage of the mixed lineage leukemia gene product (MLL1) by taspase1 using kinase inhibitors |
| WO2023126951A1 (en) * | 2022-01-03 | 2023-07-06 | Yeda Research And Development Co. Ltd. | Inhibitors of autophagy-related protein-protein interactions |
| GB202213166D0 (en) * | 2022-09-08 | 2022-10-26 | Cambridge Entpr Ltd | Novel compounds, compositions and therapeutic uses thereof |
| GB202213163D0 (en) * | 2022-09-08 | 2022-10-26 | Cambridge Entpr Ltd | Novel compounds, compositions and therapeutic uses thereof |
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| US5559235A (en) | 1991-10-29 | 1996-09-24 | Glaxo Wellcome Inc. | Water soluble camptothecin derivatives |
| US5342947A (en) | 1992-10-09 | 1994-08-30 | Glaxo Inc. | Preparation of water soluble camptothecin derivatives |
| US5681835A (en) | 1994-04-25 | 1997-10-28 | Glaxo Wellcome Inc. | Non-steroidal ligands for the estrogen receptor |
| US5491237A (en) | 1994-05-03 | 1996-02-13 | Glaxo Wellcome Inc. | Intermediates in pharmaceutical camptothecin preparation |
| US5624677A (en) | 1995-06-13 | 1997-04-29 | Pentech Pharmaceuticals, Inc. | Controlled release of drugs delivered by sublingual or buccal administration |
| GB9716557D0 (en) | 1997-08-06 | 1997-10-08 | Glaxo Group Ltd | Benzylidene-1,3-dihydro-indol-2-one derivatives having anti-cancer activity |
| ES2270867T3 (es) | 1999-09-23 | 2007-04-16 | Astrazeneca Ab | Compuestos de quinazolina terapeuticos. |
| TW200526626A (en) | 2003-09-13 | 2005-08-16 | Astrazeneca Ab | Chemical compounds |
| BRPI0607748A2 (pt) | 2005-02-17 | 2017-05-23 | Amr Tech Inc | composto, composição farmacêutica, e, método de tratamento de um distúrbio |
| JP5399905B2 (ja) * | 2006-09-01 | 2014-01-29 | センワ バイオサイエンシズ インコーポレイテッド | セリン−トレオニンタンパク質キナーゼおよびｐａｒｐ調節因子 |
| AU2009219154A1 (en) * | 2008-02-29 | 2009-09-03 | Cylene Pharmaceuticals, Inc. | Protein kinase modulators |
| CA2735369A1 (en) * | 2008-09-10 | 2010-03-18 | Kalypsys Inc. | Heterocyclic inhibitors of histamine receptors for the treatment of disease |
| TW201204727A (en) * | 2010-03-10 | 2012-02-01 | Kalypsys Inc | Heterocyclic inhibitors of histamine receptors for the treatment of disease |
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- 2010-08-26 MX MX2012002426A patent/MX2012002426A/es not_active Application Discontinuation
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- 2010-08-26 IN IN2596DEN2012 patent/IN2012DN02596A/en unknown
- 2010-08-26 AU AU2010286691A patent/AU2010286691A1/en not_active Abandoned
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- 2010-08-26 KR KR1020127007386A patent/KR20120059571A/ko not_active Withdrawn
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- 2010-08-26 CA CA2771890A patent/CA2771890A1/en not_active Abandoned
- 2010-08-26 US US12/869,335 patent/US20110065698A1/en not_active Abandoned
- 2010-08-26 SG SG2012012845A patent/SG178552A1/en unknown
- 2010-08-26 JP JP2012526972A patent/JP2013503178A/ja active Pending
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| KR20120059571A (ko) | 2012-06-08 |
| IL218280A0 (en) | 2012-04-30 |
| CN102596969A (zh) | 2012-07-18 |
| MX2012002426A (es) | 2012-06-27 |
| IN2012DN02596A (enExample) | 2015-08-28 |
| EP2470544A1 (en) | 2012-07-04 |
| US20110065698A1 (en) | 2011-03-17 |
| WO2011025859A1 (en) | 2011-03-03 |
| AU2010286691A1 (en) | 2012-04-19 |
| BR112012004304A2 (pt) | 2016-03-15 |
| CA2771890A1 (en) | 2011-03-03 |
| SG178552A1 (en) | 2012-03-29 |
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