JP2013503171A - がんの処置および予防におけるメトホルミンの使用 - Google Patents
がんの処置および予防におけるメトホルミンの使用 Download PDFInfo
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- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2014214093A (ja) * | 2013-04-23 | 2014-11-17 | 国立大学法人岡山大学 | 免疫疲弊ｃｄ８＋ｔ細胞の機能改善薬、がん治療薬及びメタボリック症候群の予防または治療薬 |
| EP3232199A2 (en) | 2014-08-19 | 2017-10-18 | National University Corporation Okayama University | Method for enhancing immune cell function and method for assessing immune cell multifunctionality |
| JP2023528059A (ja) * | 2020-06-05 | 2023-07-03 | フロントバイオ インコーポレーテッド | 抗ウイルス剤及び抗うつ剤を有効成分として含有する癌の予防または治療用薬学的組成物 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US20130040310A1 (en) * | 2009-12-15 | 2013-02-14 | Salk Institute For Biological Studies | Ulk1 compositions, inhibitors, screening and methods of use |
| CN103347521B (zh) * | 2010-12-06 | 2018-05-25 | 全球癌症治疗有限责任公司 | 用于治疗癌症的使用化疗和免疫治疗的代谢靶向癌细胞的方法 |
| WO2012171015A2 (en) * | 2011-06-10 | 2012-12-13 | Translational Genomics Research Institute | Therapeutic combination for cancer treatment |
| CN102327256B (zh) * | 2011-09-22 | 2014-01-29 | 上海交通大学医学院附属瑞金医院 | 二甲双胍在制备治疗淋巴瘤疾病药物中的应用 |
| WO2013086002A1 (en) * | 2011-12-05 | 2013-06-13 | Cellworks Research India Private Limited | Compositions, process of preparation of said compositions and method of treating cancer |
| CN105142631A (zh) * | 2013-01-14 | 2015-12-09 | 健康诊所有限公司 | 抗癌药物和用途 |
| AU2014250795B2 (en) * | 2013-04-12 | 2019-07-18 | Ned Biosystems, Inc. | Cancer therapy |
| CN105263484B (zh) | 2013-05-24 | 2018-08-03 | 株式会社加龄.营养研究所 | 包含二甲双胍和二氢槲皮素的药物组合及其用于治疗癌症的用途 |
| US10166246B2 (en) | 2014-05-27 | 2019-01-01 | City Of Hope | TGR5 agonist complexes for treating diabetes and cancer |
| CN107205968B (zh) * | 2014-08-14 | 2021-08-20 | 威斯康星州医药大学股份有限公司 | 修饰的线粒体-二甲双胍化合物及其合成和使用方法 |
| WO2016026933A1 (en) * | 2014-08-21 | 2016-02-25 | Centre National De La Recherche Scientifique - Cnrs - | Adjuvant or neoadjuvant therapy for sensitizing cancer stem cells to chemotherapy |
| EP3417076B1 (en) * | 2016-02-16 | 2022-11-09 | Agency for Science, Technology and Research | Cancer epigenetic profiling |
| CA3059210C (en) | 2016-05-19 | 2022-07-19 | The Regents Of The University Of California | Triple drug combination (metformin, simvastatin, digoxin) for targeted treatment of pancreatic cancer |
| CN106727468A (zh) * | 2017-04-01 | 2017-05-31 | 四川大学 | 二甲双胍及联合二甲双胍和长春新碱在制备治疗白血病药物中的应用及药物组合物 |
| CA3060509A1 (en) | 2017-04-21 | 2018-10-25 | Federica Sotgia | Targeting hypoxic cancer stem cells (cscs) with doxycycline: implications for improving anti-angiogenic therapy |
| US11197872B2 (en) | 2017-04-21 | 2021-12-14 | Lunella Biotech, Inc. | Vitamin C and doxycycline: a synthetic lethal combination therapy for eradicating cancer stem cells (CSCs) |
| KR20200010343A (ko) | 2017-05-19 | 2020-01-30 | 루넬라 바이오테크 인코포레이티드 | 안티미토신: 암 줄기 세포를 근절하기 위한 미토콘드리아 생물발생의 표적화 억제제 |
| US12006553B2 (en) | 2017-05-19 | 2024-06-11 | Lunella Biotech, Inc. | Companion diagnostics for mitochondrial inhibitors |
| WO2019183003A1 (en) * | 2018-03-18 | 2019-09-26 | The University Of North Carolina At Chapel Hill | Methods and assays for endometrial diseases |
| CN111617255B (zh) * | 2019-02-28 | 2023-08-18 | 北京强新生物科技有限公司 | 用于治疗中枢神经系统紊乱的组合疗法 |
| WO2024233616A1 (en) * | 2023-05-11 | 2024-11-14 | Wainer Irving W | Method for treating cancer |
| WO2025085311A1 (en) * | 2023-10-16 | 2025-04-24 | Board Of Regents, The University Of Texas System | Methods and compositions for the treatment of kmt2d-deficient cancers |
| TW202539622A (zh) * | 2024-01-23 | 2025-10-16 | 大陸商成都夸常奧普醫療科技有限公司 | 包含n,n-二甲基亞雙胍的製劑、和包含n,n-二甲基亞雙胍與藥物的藥物組合、組合物、試劑盒及其用途和製備方法 |
Family Cites Families (6)
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|---|---|---|---|---|
| CN101056656A (zh) * | 2004-09-15 | 2007-10-17 | 哈佛大学校长及研究员协会 | 在治疗肥胖症和糖尿病中降低er应力 |
| US7465804B2 (en) * | 2005-05-20 | 2008-12-16 | Amgen Inc. | Compounds, pharmaceutical compositions and methods for their use in treating metabolic disorders |
| DE102006026026A1 (de) * | 2006-06-01 | 2007-12-06 | Grünenthal GmbH | Arzneimittel |
| WO2008097861A2 (en) * | 2007-02-02 | 2008-08-14 | Braincells, Inc. | MODULATION OF NEUROGENESIS WITH BIGUANIDES AND GSK3-ß AGENTS |
| WO2008110491A2 (en) * | 2007-03-09 | 2008-09-18 | University Of Basel | Chemotherapy of neoplastic diseases using combinations of rapamycin and compounds modulating mtor pathway alone or in combination with heat |
| WO2009101199A2 (en) * | 2008-02-15 | 2009-08-20 | Bodo Melnik | Treatment of acne vulgaris; rosacea and rhinophym |
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- 2010-08-25 EP EP10815838A patent/EP2470170A4/en not_active Withdrawn
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- 2010-08-25 CA CA2772120A patent/CA2772120A1/en not_active Abandoned
- 2010-08-25 IN IN1964DEN2012 patent/IN2012DN01964A/en unknown
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2014214093A (ja) * | 2013-04-23 | 2014-11-17 | 国立大学法人岡山大学 | 免疫疲弊ｃｄ８＋ｔ細胞の機能改善薬、がん治療薬及びメタボリック症候群の予防または治療薬 |
| EP3232199A2 (en) | 2014-08-19 | 2017-10-18 | National University Corporation Okayama University | Method for enhancing immune cell function and method for assessing immune cell multifunctionality |
| JP2023528059A (ja) * | 2020-06-05 | 2023-07-03 | フロントバイオ インコーポレーテッド | 抗ウイルス剤及び抗うつ剤を有効成分として含有する癌の予防または治療用薬学的組成物 |
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| BR112012004281A2 (pt) | 2016-03-08 |
| CN102596192A (zh) | 2012-07-18 |
| IL218287A0 (en) | 2012-04-30 |
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| EP2470170A4 (en) | 2013-01-02 |
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| MX2012002337A (es) | 2012-06-25 |
| KR20120080579A (ko) | 2012-07-17 |
| CA2772120A1 (en) | 2011-03-17 |
| WO2011031474A2 (en) | 2011-03-17 |
| IN2012DN01964A (https=) | 2015-08-21 |
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| WO2011031474A3 (en) | 2011-06-16 |
| US20120220664A1 (en) | 2012-08-30 |
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