JP2013501007A5 - - Google Patents
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- Publication number
- JP2013501007A5 JP2013501007A5 JP2012523169A JP2012523169A JP2013501007A5 JP 2013501007 A5 JP2013501007 A5 JP 2013501007A5 JP 2012523169 A JP2012523169 A JP 2012523169A JP 2012523169 A JP2012523169 A JP 2012523169A JP 2013501007 A5 JP2013501007 A5 JP 2013501007A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- seq
- identity
- variant
- immunogenic fragment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229920001184 polypeptide Polymers 0.000 claims 66
- 102000004196 processed proteins & peptides Human genes 0.000 claims 66
- 108090000765 processed proteins & peptides Proteins 0.000 claims 66
- 241000605862 Porphyromonas gingivalis Species 0.000 claims 51
- 230000002163 immunogen Effects 0.000 claims 44
- 239000012634 fragment Substances 0.000 claims 40
- 102000004169 proteins and genes Human genes 0.000 claims 40
- 108090000623 proteins and genes Proteins 0.000 claims 40
- 102000039446 nucleic acids Human genes 0.000 claims 12
- 108020004707 nucleic acids Proteins 0.000 claims 12
- 150000007523 nucleic acids Chemical class 0.000 claims 12
- 208000015181 infectious disease Diseases 0.000 claims 11
- 239000002671 adjuvant Substances 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 230000002265 prevention Effects 0.000 claims 2
- 230000028993 immune response Effects 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23071709P | 2009-08-02 | 2009-08-02 | |
| US61/230,717 | 2009-08-02 | ||
| PCT/CA2010/001177 WO2011014947A1 (en) | 2009-08-02 | 2010-07-30 | Porphyromonas gingivalis polypeptides |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015133497A Division JP2015178533A (ja) | 2009-08-02 | 2015-07-02 | ポルフィロモナス・ジンジバリス（Ｐｏｒｐｈｙｒｏｍｏｎａｓｇｉｎｇｉｖａｌｉｓ）ポリペプチド |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013501007A JP2013501007A (ja) | 2013-01-10 |
| JP2013501007A5 true JP2013501007A5 (cg-RX-API-DMAC7.html) | 2013-09-12 |
| JP5876411B2 JP5876411B2 (ja) | 2016-03-02 |
Family
ID=43543841
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012523169A Expired - Fee Related JP5876411B2 (ja) | 2009-08-02 | 2010-07-30 | ポルフィロモナス・ジンジバリス（Ｐｏｒｐｈｙｒｏｍｏｎａｓｇｉｎｇｉｖａｌｉｓ）ポリペプチド |
| JP2015133497A Pending JP2015178533A (ja) | 2009-08-02 | 2015-07-02 | ポルフィロモナス・ジンジバリス（Ｐｏｒｐｈｙｒｏｍｏｎａｓｇｉｎｇｉｖａｌｉｓ）ポリペプチド |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015133497A Pending JP2015178533A (ja) | 2009-08-02 | 2015-07-02 | ポルフィロモナス・ジンジバリス（Ｐｏｒｐｈｙｒｏｍｏｎａｓｇｉｎｇｉｖａｌｉｓ）ポリペプチド |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US9366673B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2462160A4 (cg-RX-API-DMAC7.html) |
| JP (2) | JP5876411B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR20120050469A (cg-RX-API-DMAC7.html) |
| CN (1) | CN102712693A (cg-RX-API-DMAC7.html) |
| AR (1) | AR085167A1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU2010281313B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112012002429A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2769231A1 (cg-RX-API-DMAC7.html) |
| IL (1) | IL217861A0 (cg-RX-API-DMAC7.html) |
| MX (1) | MX2012001495A (cg-RX-API-DMAC7.html) |
| RU (1) | RU2012107993A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2011014947A1 (cg-RX-API-DMAC7.html) |
| ZA (1) | ZA201200799B (cg-RX-API-DMAC7.html) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8871213B2 (en) | 2008-08-29 | 2014-10-28 | Oral Health Australia Pty Ltd | Prevention, treatment and diagnosis of P. gingivalis infection |
| MY162557A (en) * | 2010-02-26 | 2017-06-15 | Oral Health Australia Pty Ltd | Treatment or prevention of infection |
| WO2014089706A1 (en) * | 2012-12-14 | 2014-06-19 | Sanofi Pasteur, Ltd. | Methods for assessing immunogenicity |
| US20160347829A1 (en) * | 2015-05-27 | 2016-12-01 | Merial Inc. | Compositions containing antimicrobial IgY antibodies, for treatment and prevention of disorders and diseases caused by oral health compromising (OHC) microorganisms |
| EA202090908A1 (ru) | 2017-10-12 | 2020-10-29 | Ваксайт, Инк. | Вакцина и связанные композиции для лечения пародонтита и способ применения |
| US20230204594A1 (en) * | 2021-11-17 | 2023-06-29 | Nerd Bio Llc | Systems and methods for real-time cellular drug-target engagement |
| CN114469863B (zh) * | 2021-11-26 | 2023-09-26 | 南方医科大学南方医院 | 甾醇脂质体作为牙髓和牙本质药物传递系统的应用 |
| CN116474096A (zh) * | 2022-01-14 | 2023-07-25 | 中山大学附属口腔医院 | 靶向牙龈卟啉单胞菌RgpB在结直肠癌的治疗及预防中的应用 |
| US20250289872A1 (en) * | 2022-04-26 | 2025-09-18 | K-Bio Investment, Llc | Formulation for antigen-binding molecules that bind to porphyromonas gingivalis |
| CN120359045A (zh) * | 2022-09-16 | 2025-07-22 | 英国Qjm生物信息有限公司 | 针对牙龈卟啉单胞菌的抗体和使用方法 |
| TW202517779A (zh) | 2023-07-19 | 2025-05-01 | 法商賽諾菲公司 | 牙齦卟啉單胞菌抗原性構築體 |
| CN116751292B (zh) * | 2023-07-31 | 2024-05-14 | 河南大学 | 牙龈卟啉单胞菌Mfa1单克隆抗体及其应用 |
| CN119424610A (zh) * | 2024-12-05 | 2025-02-14 | 重庆师范大学 | 具备抗衰老活性的重组蛋白制剂及其制备方法、应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0888124A4 (en) * | 1996-03-22 | 2001-04-11 | Univ Georgia Res Found | Immunogenic assemblies of Porphyromonas Gingivalis peptides and their methods |
| AUPN901296A0 (en) * | 1996-03-29 | 1996-04-26 | University Of Melbourne, The | Porphyromonas gingivalis antigens for the diagnosis and treatment of periodontitis |
| NZ504811A (en) * | 1997-12-10 | 2003-10-31 | Csl Ltd | Porphorymonas gingivalis polypeptides and nucleotides |
| JP2003192616A (ja) * | 2001-12-27 | 2003-07-09 | Univ Nihon | 歯周病用ｄｎａワクチン |
| JP2003286191A (ja) * | 2002-03-27 | 2003-10-07 | Univ Nihon | 歯周病用粘膜免疫ワクチン |
| WO2004083425A1 (ja) * | 2003-03-17 | 2004-09-30 | Kirin Beer Kabushiki Kaisha | 歯周病治療剤 |
| JP2005179301A (ja) * | 2003-12-22 | 2005-07-07 | Univ Nihon | 歯周病用経皮免疫ワクチン |
| CA2652957A1 (en) | 2006-06-27 | 2008-01-03 | Oral Health Australia Pty Ltd. | Porphyromonas gingivalis polypeptides useful in the prevention of periodontal disease |
| EP2176413A4 (en) * | 2007-07-12 | 2012-08-01 | Oral Health Australia Pty Ltd | IMMUNOLOGY TREATMENT FOR BIOFILMS |
-
2010
- 2010-07-30 CA CA2769231A patent/CA2769231A1/en not_active Abandoned
- 2010-07-30 KR KR1020127005748A patent/KR20120050469A/ko not_active Ceased
- 2010-07-30 AU AU2010281313A patent/AU2010281313B2/en not_active Ceased
- 2010-07-30 RU RU2012107993/10A patent/RU2012107993A/ru not_active Application Discontinuation
- 2010-07-30 BR BR112012002429A patent/BR112012002429A2/pt active Search and Examination
- 2010-07-30 US US13/388,042 patent/US9366673B2/en not_active Expired - Fee Related
- 2010-07-30 JP JP2012523169A patent/JP5876411B2/ja not_active Expired - Fee Related
- 2010-07-30 EP EP10805906.4A patent/EP2462160A4/en not_active Withdrawn
- 2010-07-30 WO PCT/CA2010/001177 patent/WO2011014947A1/en not_active Ceased
- 2010-07-30 CN CN2010800451190A patent/CN102712693A/zh active Pending
- 2010-07-30 MX MX2012001495A patent/MX2012001495A/es unknown
- 2010-08-03 AR ARP100102836A patent/AR085167A1/es unknown
-
2012
- 2012-01-31 IL IL217861A patent/IL217861A0/en unknown
- 2012-02-01 ZA ZA2012/00799A patent/ZA201200799B/en unknown
-
2015
- 2015-07-02 JP JP2015133497A patent/JP2015178533A/ja active Pending