JP2013107903A5 - - Google Patents

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Publication number
JP2013107903A5
JP2013107903A5 JP2013045053A JP2013045053A JP2013107903A5 JP 2013107903 A5 JP2013107903 A5 JP 2013107903A5 JP 2013045053 A JP2013045053 A JP 2013045053A JP 2013045053 A JP2013045053 A JP 2013045053A JP 2013107903 A5 JP2013107903 A5 JP 2013107903A5
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JP
Japan
Prior art keywords
bis
composition
phenylene
methylene
pharmaceutically acceptable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2013045053A
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English (en)
Japanese (ja)
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JP2013107903A (ja
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Publication date
Application filed filed Critical
Publication of JP2013107903A publication Critical patent/JP2013107903A/ja
Publication of JP2013107903A5 publication Critical patent/JP2013107903A5/ja
Pending legal-status Critical Current

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JP2013045053A 2005-08-19 2013-03-07 化学療法の強化方法 Pending JP2013107903A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US70997805P 2005-08-19 2005-08-19
US60/709,978 2005-08-19
US73473605P 2005-11-08 2005-11-08
US60/734,736 2005-11-08

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2008527219A Division JP2009504788A (ja) 2005-08-19 2006-08-21 化学療法の強化方法

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2013169087A Division JP2013231086A (ja) 2005-08-19 2013-08-16 化学療法の強化方法

Publications (2)

Publication Number Publication Date
JP2013107903A JP2013107903A (ja) 2013-06-06
JP2013107903A5 true JP2013107903A5 (https=) 2013-10-03

Family

ID=37758501

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2008527219A Pending JP2009504788A (ja) 2005-08-19 2006-08-21 化学療法の強化方法
JP2013045053A Pending JP2013107903A (ja) 2005-08-19 2013-03-07 化学療法の強化方法
JP2013169087A Pending JP2013231086A (ja) 2005-08-19 2013-08-16 化学療法の強化方法

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2008527219A Pending JP2009504788A (ja) 2005-08-19 2006-08-21 化学療法の強化方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2013169087A Pending JP2013231086A (ja) 2005-08-19 2013-08-16 化学療法の強化方法

Country Status (9)

Country Link
US (1) US20070043012A1 (https=)
EP (1) EP1951046B1 (https=)
JP (3) JP2009504788A (https=)
CN (1) CN101365336B (https=)
AU (1) AU2006280945A1 (https=)
BR (1) BRPI0615180A2 (https=)
CA (1) CA2619828A1 (https=)
IL (1) IL189599A0 (https=)
WO (1) WO2007022523A2 (https=)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10149889B2 (en) * 2005-11-25 2018-12-11 Rutgers, The State University Of New Jersey Compositions for the treatment of cancer, and methods for testing and using the same
US8926990B2 (en) 2009-10-13 2015-01-06 Rutgers, The State University Of New Jersey Treatment and diagnosis of inflammatory disorders and HIV
CA2673719C (en) * 2006-12-21 2018-07-24 Biokine Therapeutics Ltd. T-140 peptide analogs having cxcr4 super-agonist activity for bone marrow recovery
US20080214509A1 (en) * 2007-03-02 2008-09-04 Robert Kerbel Methods for enhancing the efficacy of vascular disrupting agents
JP2012516353A (ja) * 2009-01-30 2012-07-19 ジェンザイム・コーポレーション 血液系悪性腫瘍を治療するための方法及び組成物
US9427456B2 (en) 2009-06-14 2016-08-30 Biokine Therapeutics Ltd. Peptide therapy for increasing platelet levels
US20110207814A1 (en) * 2009-12-23 2011-08-25 Pranela Rameshwar Combination Therapy for Breast Cancer Treatment
US20130310442A1 (en) * 2010-09-09 2013-11-21 Noxxon Pharma Ag SDF-1 Binding Nucleic Acids and the use Thereof in Cancer Treatment
RU2638802C2 (ru) 2011-05-16 2017-12-15 Джензим Корпорейшн Применение антагонистов cxcr4
US9439942B2 (en) 2012-04-24 2016-09-13 Biokine Therapeutics Ltd. Peptides and use thereof in the treatment of large cell lung cancer
EP2978439B1 (en) 2013-03-24 2017-08-16 Biokine Therapeutics Ltd. A combination of a cxcr4 antagonist and cytarabine for use in treating myeloid leukemia
CA2928315C (en) 2013-10-31 2023-03-21 Biokine Therapeutics Ltd. Methods of treating acute myeloid leukemia with a flt3 mutation
EP3125919A4 (en) * 2014-02-19 2018-01-03 Microconstants China Inc. Chemokine receptor antagonist and its combinational therapy
KR101759688B1 (ko) * 2015-01-16 2017-07-20 서울대학교산학협력단 사이클램 유도체 화합물 및 이의 약학적 용도
WO2016114634A2 (ko) * 2015-01-16 2016-07-21 서울대학교 산학협력단 사이클램 유도체 화합물 및 이의 약학적 용도
EP3288638A1 (en) * 2015-04-25 2018-03-07 The General Hospital Corporation Anti-fugetactic agent and anti-cancer agent combination therapy and compositions for the treatment of cancer
CA3026154A1 (en) 2015-06-03 2016-12-08 The University Of Queensland Mobilizing agents and uses therefor
IL274572B2 (en) 2015-07-16 2024-01-01 Biolinerx Ltd Compositions and methods for treating cancer
CN108348545A (zh) * 2015-09-18 2018-07-31 综合医院公司以麻省总医院名义经营 具有抗趋除特性的修饰的t细胞及其用途
CN109069426B (zh) * 2015-12-14 2021-10-29 X4 制药有限公司 治疗癌症的方法
WO2017106332A1 (en) 2015-12-14 2017-06-22 X4 Pharmaceuticals, Inc. Methods for treating cancer
CN109310733A (zh) 2016-02-23 2019-02-05 百欧林纳克斯有限公司 治疗急性骨髓性白血病的方法
US11337969B2 (en) 2016-04-08 2022-05-24 X4 Pharmaceuticals, Inc. Methods for treating cancer
ES2870920T3 (es) 2016-06-21 2021-10-28 X4 Pharmaceuticals Inc Inhibidores de CXCR4 y usos de los mismos
CN109640988A (zh) 2016-06-21 2019-04-16 X4 制药有限公司 Cxcr4抑制剂及其用途
WO2017223243A1 (en) 2016-06-21 2017-12-28 X4 Pharmaceuticals, Inc. Cxcr4 inhibitors and uses thereof
JP2020525427A (ja) * 2017-06-21 2020-08-27 エックス4 ファーマシューティカルズ, インコーポレイテッド 癌を処置するための方法
US10548889B1 (en) 2018-08-31 2020-02-04 X4 Pharmaceuticals, Inc. Compositions of CXCR4 inhibitors and methods of preparation and use
EP3856225A1 (en) 2018-09-25 2021-08-04 BioLineRx Ltd. Methods of selecting treatment for cxcr4-associated cancer
CA3171250A1 (en) 2020-03-10 2021-09-16 E. Lynne KELLEY Methods for treating neutropenia
TWI781469B (zh) * 2020-10-27 2022-10-21 行政院原子能委員會核能研究所 複合物、造影劑及治療與cxcr4接受體相關疾病的用途

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4005204A (en) * 1973-03-23 1977-01-25 Burroughs Wellcome Co. Treatment of neoplasms in the brain with diamino dichloroalkyl pyrimidine
US6001826A (en) 1989-12-21 1999-12-14 Anormed, Inc. Chemical compounds
US5021409A (en) 1989-12-21 1991-06-04 Johnson Matthey Plc Antiviral cyclic polyamines
GB9105489D0 (en) 1991-03-15 1991-05-01 Johnson Matthey Plc Improvements in chemical compounds
GB9126677D0 (en) 1991-12-16 1992-02-12 Johnson Matthey Plc Improvements in chemical compounds
GB9400411D0 (en) 1994-01-11 1994-03-09 Johnson Matthey Plc Improvements in chemical compounds
GB9511357D0 (en) * 1995-06-06 1995-08-02 Johnson Matthey Plc Improved antiviral compounds
US6506770B1 (en) * 1996-06-06 2003-01-14 Anormed, Inc. Antiviral compounds
CA2305787A1 (en) * 2000-05-09 2001-11-09 The University Of British Columbia Cxcr4 antagonist treatment of hematopoietic cells
BR0010655A (pt) 1999-03-24 2002-02-13 Anormed Inc Compostos heterocìclicos para ligação ao receptor de quimiocina
DE60042030D1 (de) 1999-12-17 2009-05-28 Genzyme Corp Chemokinrezeptor-bindende heterocyclische verbindungen
PT1317451E (pt) 2000-09-15 2006-12-29 Anormed Inc Compostos heterocíclicos que se ligam a receptores de quimioquinas
CA2419224A1 (en) 2000-09-15 2002-03-21 Anormed Inc. Chemokine receptor binding heterocyclic compounds
US6835731B2 (en) 2000-09-15 2004-12-28 Anormed, Inc. Chemokine receptor binding heterocyclic compounds
EP1351678A2 (en) * 2001-01-02 2003-10-15 Elizabeth Shanahan-Prendergast Treatment for inhibiting neoplastic lesions using incensole and/or furanogermacrens
EP1361851B1 (en) 2001-01-23 2007-02-21 P & G-Clairol, Inc. Primary intermediates for oxidative coloration of hair
ES2380009T3 (es) * 2001-07-31 2012-05-07 Genzyme Global S.A.R.L. Métodos para movilizar las células madre/progenitoras
US7169750B2 (en) * 2001-07-31 2007-01-30 Anormed, Inc. Methods to mobilize progenitor/stem cells
CA2467718C (en) 2001-12-21 2011-04-26 Anormed Inc. Chemokine receptor binding heterocyclic compounds with enhanced efficacy
JP2006524242A (ja) * 2003-03-27 2006-10-26 エモリー ユニバーシティー Cxcr4アンタゴニストおよびそれらの使用方法
US20040202935A1 (en) 2003-04-08 2004-10-14 Jeremy Barker Cathode active material with increased alkali/metal content and method of making same
EP1613613B1 (en) 2003-04-11 2021-06-02 Genzyme Corporation Cxcr4 chemokine receptor binding compounds
ATE514434T1 (de) * 2004-02-25 2011-07-15 Dana Farber Cancer Inst Inc Hemmer des insulinartigen wachstumsfaktor- rezeptors-1 zur hemmung von tumorzellwachstum
JP2008509928A (ja) * 2004-08-13 2008-04-03 アノーメド インコーポレイテッド 前駆/幹細胞を動員するためのケモカインの組み合わせ
US7825088B2 (en) * 2005-04-25 2010-11-02 The Cbr Institute For Biomedical Research, Inc. Methods for the treatment of multiple myeloma
US8569280B2 (en) * 2005-04-25 2013-10-29 Immune Disease Institute Methods for the treatment of multiple myeloma
MX2008010895A (es) * 2006-02-24 2008-09-03 Genzyme Corp Metodos para aumentar el flujo sanguineo y/o promover la regeneracion de tejidos.

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