BRPI0615180A2 - método para intensificar a quimioterapia - Google Patents
método para intensificar a quimioterapia Download PDFInfo
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- BRPI0615180A2 BRPI0615180A2 BRPI0615180-9A BRPI0615180A BRPI0615180A2 BR PI0615180 A2 BRPI0615180 A2 BR PI0615180A2 BR PI0615180 A BRPI0615180 A BR PI0615180A BR PI0615180 A2 BRPI0615180 A2 BR PI0615180A2
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- Prior art keywords
- formula
- ring
- optionally substituted
- alkyl
- substituted
- Prior art date
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- 238000000034 method Methods 0.000 title claims abstract description 64
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Landscapes
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- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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| US73473605P | 2005-11-08 | 2005-11-08 | |
| US60/734,736 | 2005-11-08 | ||
| PCT/US2006/032668 WO2007022523A2 (en) | 2005-08-19 | 2006-08-21 | Methods to enhance chemotherapy |
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| IL (1) | IL189599A0 (https=) |
| WO (1) | WO2007022523A2 (https=) |
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| US8926990B2 (en) | 2009-10-13 | 2015-01-06 | Rutgers, The State University Of New Jersey | Treatment and diagnosis of inflammatory disorders and HIV |
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| US9427456B2 (en) | 2009-06-14 | 2016-08-30 | Biokine Therapeutics Ltd. | Peptide therapy for increasing platelet levels |
| US20110207814A1 (en) * | 2009-12-23 | 2011-08-25 | Pranela Rameshwar | Combination Therapy for Breast Cancer Treatment |
| US20130310442A1 (en) * | 2010-09-09 | 2013-11-21 | Noxxon Pharma Ag | SDF-1 Binding Nucleic Acids and the use Thereof in Cancer Treatment |
| RU2638802C2 (ru) | 2011-05-16 | 2017-12-15 | Джензим Корпорейшн | Применение антагонистов cxcr4 |
| US9439942B2 (en) | 2012-04-24 | 2016-09-13 | Biokine Therapeutics Ltd. | Peptides and use thereof in the treatment of large cell lung cancer |
| EP2978439B1 (en) | 2013-03-24 | 2017-08-16 | Biokine Therapeutics Ltd. | A combination of a cxcr4 antagonist and cytarabine for use in treating myeloid leukemia |
| CA2928315C (en) | 2013-10-31 | 2023-03-21 | Biokine Therapeutics Ltd. | Methods of treating acute myeloid leukemia with a flt3 mutation |
| EP3125919A4 (en) * | 2014-02-19 | 2018-01-03 | Microconstants China Inc. | Chemokine receptor antagonist and its combinational therapy |
| KR101759688B1 (ko) * | 2015-01-16 | 2017-07-20 | 서울대학교산학협력단 | 사이클램 유도체 화합물 및 이의 약학적 용도 |
| WO2016114634A2 (ko) * | 2015-01-16 | 2016-07-21 | 서울대학교 산학협력단 | 사이클램 유도체 화합물 및 이의 약학적 용도 |
| EP3288638A1 (en) * | 2015-04-25 | 2018-03-07 | The General Hospital Corporation | Anti-fugetactic agent and anti-cancer agent combination therapy and compositions for the treatment of cancer |
| CA3026154A1 (en) | 2015-06-03 | 2016-12-08 | The University Of Queensland | Mobilizing agents and uses therefor |
| IL274572B2 (en) | 2015-07-16 | 2024-01-01 | Biolinerx Ltd | Compositions and methods for treating cancer |
| CN108348545A (zh) * | 2015-09-18 | 2018-07-31 | 综合医院公司以麻省总医院名义经营 | 具有抗趋除特性的修饰的t细胞及其用途 |
| CN109069426B (zh) * | 2015-12-14 | 2021-10-29 | X4 制药有限公司 | 治疗癌症的方法 |
| WO2017106332A1 (en) | 2015-12-14 | 2017-06-22 | X4 Pharmaceuticals, Inc. | Methods for treating cancer |
| CN109310733A (zh) | 2016-02-23 | 2019-02-05 | 百欧林纳克斯有限公司 | 治疗急性骨髓性白血病的方法 |
| US11337969B2 (en) | 2016-04-08 | 2022-05-24 | X4 Pharmaceuticals, Inc. | Methods for treating cancer |
| ES2870920T3 (es) | 2016-06-21 | 2021-10-28 | X4 Pharmaceuticals Inc | Inhibidores de CXCR4 y usos de los mismos |
| CN109640988A (zh) | 2016-06-21 | 2019-04-16 | X4 制药有限公司 | Cxcr4抑制剂及其用途 |
| WO2017223243A1 (en) | 2016-06-21 | 2017-12-28 | X4 Pharmaceuticals, Inc. | Cxcr4 inhibitors and uses thereof |
| JP2020525427A (ja) * | 2017-06-21 | 2020-08-27 | エックス４ ファーマシューティカルズ， インコーポレイテッド | 癌を処置するための方法 |
| US10548889B1 (en) | 2018-08-31 | 2020-02-04 | X4 Pharmaceuticals, Inc. | Compositions of CXCR4 inhibitors and methods of preparation and use |
| EP3856225A1 (en) | 2018-09-25 | 2021-08-04 | BioLineRx Ltd. | Methods of selecting treatment for cxcr4-associated cancer |
| CA3171250A1 (en) | 2020-03-10 | 2021-09-16 | E. Lynne KELLEY | Methods for treating neutropenia |
| TWI781469B (zh) * | 2020-10-27 | 2022-10-21 | 行政院原子能委員會核能研究所 | 複合物、造影劑及治療與cxcr4接受體相關疾病的用途 |
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| GB9105489D0 (en) | 1991-03-15 | 1991-05-01 | Johnson Matthey Plc | Improvements in chemical compounds |
| GB9126677D0 (en) | 1991-12-16 | 1992-02-12 | Johnson Matthey Plc | Improvements in chemical compounds |
| GB9400411D0 (en) | 1994-01-11 | 1994-03-09 | Johnson Matthey Plc | Improvements in chemical compounds |
| GB9511357D0 (en) * | 1995-06-06 | 1995-08-02 | Johnson Matthey Plc | Improved antiviral compounds |
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| BR0010655A (pt) | 1999-03-24 | 2002-02-13 | Anormed Inc | Compostos heterocìclicos para ligação ao receptor de quimiocina |
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| US20040202935A1 (en) | 2003-04-08 | 2004-10-14 | Jeremy Barker | Cathode active material with increased alkali/metal content and method of making same |
| EP1613613B1 (en) | 2003-04-11 | 2021-06-02 | Genzyme Corporation | Cxcr4 chemokine receptor binding compounds |
| ATE514434T1 (de) * | 2004-02-25 | 2011-07-15 | Dana Farber Cancer Inst Inc | Hemmer des insulinartigen wachstumsfaktor- rezeptors-1 zur hemmung von tumorzellwachstum |
| JP2008509928A (ja) * | 2004-08-13 | 2008-04-03 | アノーメド インコーポレイテッド | 前駆／幹細胞を動員するためのケモカインの組み合わせ |
| US7825088B2 (en) * | 2005-04-25 | 2010-11-02 | The Cbr Institute For Biomedical Research, Inc. | Methods for the treatment of multiple myeloma |
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| MX2008010895A (es) * | 2006-02-24 | 2008-09-03 | Genzyme Corp | Metodos para aumentar el flujo sanguineo y/o promover la regeneracion de tejidos. |
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- 2006-08-21 JP JP2008527219A patent/JP2009504788A/ja active Pending
- 2006-08-21 EP EP06813613A patent/EP1951046B1/en not_active Revoked
- 2006-08-21 WO PCT/US2006/032668 patent/WO2007022523A2/en not_active Ceased
- 2006-08-21 AU AU2006280945A patent/AU2006280945A1/en not_active Abandoned
- 2006-08-21 CN CN2006800350846A patent/CN101365336B/zh not_active Expired - Fee Related
- 2006-08-21 BR BRPI0615180-9A patent/BRPI0615180A2/pt not_active IP Right Cessation
- 2006-08-21 US US11/507,717 patent/US20070043012A1/en not_active Abandoned
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2008
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2013
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- 2013-08-16 JP JP2013169087A patent/JP2013231086A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2007022523A3 (en) | 2007-11-22 |
| IL189599A0 (en) | 2008-08-07 |
| EP1951046B1 (en) | 2012-07-18 |
| US20070043012A1 (en) | 2007-02-22 |
| CA2619828A1 (en) | 2007-02-22 |
| JP2013231086A (ja) | 2013-11-14 |
| JP2009504788A (ja) | 2009-02-05 |
| CN101365336B (zh) | 2013-05-29 |
| AU2006280945A1 (en) | 2007-02-22 |
| WO2007022523A2 (en) | 2007-02-22 |
| CN101365336A (zh) | 2009-02-11 |
| EP1951046A4 (en) | 2010-03-17 |
| JP2013107903A (ja) | 2013-06-06 |
| EP1951046A2 (en) | 2008-08-06 |
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