JP2013107903A5 - - Google Patents
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- Publication number
- JP2013107903A5 JP2013107903A5 JP2013045053A JP2013045053A JP2013107903A5 JP 2013107903 A5 JP2013107903 A5 JP 2013107903A5 JP 2013045053 A JP2013045053 A JP 2013045053A JP 2013045053 A JP2013045053 A JP 2013045053A JP 2013107903 A5 JP2013107903 A5 JP 2013107903A5
- Authority
- JP
- Japan
- Prior art keywords
- bis
- composition
- phenylene
- methylene
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US70997805P | 2005-08-19 | 2005-08-19 | |
| US60/709,978 | 2005-08-19 | ||
| US73473605P | 2005-11-08 | 2005-11-08 | |
| US60/734,736 | 2005-11-08 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008527219A Division JP2009504788A (ja) | 2005-08-19 | 2006-08-21 | 化学療法の強化方法 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013169087A Division JP2013231086A (ja) | 2005-08-19 | 2013-08-16 | 化学療法の強化方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013107903A JP2013107903A (ja) | 2013-06-06 |
| JP2013107903A5 true JP2013107903A5 (enExample) | 2013-10-03 |
Family
ID=37758501
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008527219A Pending JP2009504788A (ja) | 2005-08-19 | 2006-08-21 | 化学療法の強化方法 |
| JP2013045053A Pending JP2013107903A (ja) | 2005-08-19 | 2013-03-07 | 化学療法の強化方法 |
| JP2013169087A Pending JP2013231086A (ja) | 2005-08-19 | 2013-08-16 | 化学療法の強化方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008527219A Pending JP2009504788A (ja) | 2005-08-19 | 2006-08-21 | 化学療法の強化方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013169087A Pending JP2013231086A (ja) | 2005-08-19 | 2013-08-16 | 化学療法の強化方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20070043012A1 (enExample) |
| EP (1) | EP1951046B1 (enExample) |
| JP (3) | JP2009504788A (enExample) |
| CN (1) | CN101365336B (enExample) |
| AU (1) | AU2006280945A1 (enExample) |
| BR (1) | BRPI0615180A2 (enExample) |
| CA (1) | CA2619828A1 (enExample) |
| IL (1) | IL189599A0 (enExample) |
| WO (1) | WO2007022523A2 (enExample) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10149889B2 (en) * | 2005-11-25 | 2018-12-11 | Rutgers, The State University Of New Jersey | Compositions for the treatment of cancer, and methods for testing and using the same |
| US8926990B2 (en) | 2009-10-13 | 2015-01-06 | Rutgers, The State University Of New Jersey | Treatment and diagnosis of inflammatory disorders and HIV |
| EP3011961B1 (en) * | 2006-12-21 | 2020-11-11 | Biokine Therapeutics LTD. | 4f-benzoyl-tn14003 for the mobilisation of hematopoietic progenitor cells in view of transplantation |
| WO2008109076A1 (en) * | 2007-03-02 | 2008-09-12 | Oxigene, Inc. | Methods for enhancing the efficacy of vascular disrupting agents |
| JP2012516353A (ja) * | 2009-01-30 | 2012-07-19 | ジェンザイム・コーポレーション | 血液系悪性腫瘍を治療するための方法及び組成物 |
| US9427456B2 (en) | 2009-06-14 | 2016-08-30 | Biokine Therapeutics Ltd. | Peptide therapy for increasing platelet levels |
| US20110207814A1 (en) * | 2009-12-23 | 2011-08-25 | Pranela Rameshwar | Combination Therapy for Breast Cancer Treatment |
| SG188220A1 (en) * | 2010-09-09 | 2013-04-30 | Noxxon Pharma Ag | Sdf-1 binding nucleic acids and the use thereof in cancer treatment |
| RU2638802C2 (ru) | 2011-05-16 | 2017-12-15 | Джензим Корпорейшн | Применение антагонистов cxcr4 |
| WO2013160895A1 (en) | 2012-04-24 | 2013-10-31 | Biokine Therapeutics Ltd. | Peptides and use thereof in the treatment of large cell lung cancer |
| CN105163749B (zh) | 2013-03-24 | 2018-03-27 | 拜欧肯治疗有限公司 | 治疗骨髓性白血病的方法 |
| EP3062809B1 (en) | 2013-10-31 | 2020-07-08 | Biokine Therapeutics Ltd. | A cxcr4 peptide inhibitor for use in treating acute myeloid leukemia with a flt3 mutation |
| JP2017508005A (ja) * | 2014-02-19 | 2017-03-23 | マイクロコンスタンツ チャイナ インク | ケモカイン受容体アンタゴニストおよびその併用療法 |
| KR101759688B1 (ko) * | 2015-01-16 | 2017-07-20 | 서울대학교산학협력단 | 사이클램 유도체 화합물 및 이의 약학적 용도 |
| WO2016114634A2 (ko) * | 2015-01-16 | 2016-07-21 | 서울대학교 산학협력단 | 사이클램 유도체 화합물 및 이의 약학적 용도 |
| MX2017013668A (es) * | 2015-04-25 | 2018-07-06 | Massachusetts Gen Hospital | Terapia de combinacion de agente anti-fuctactico y agente anti-cancer y composiciones para el tratamiento de cancer. |
| WO2016191811A1 (en) | 2015-06-03 | 2016-12-08 | The University Of Queensland | Mobilizing agents and uses therefor |
| MX2017016844A (es) | 2015-07-16 | 2018-08-15 | Biokine Therapeutics Ltd | Composiciones y procedimientos para tratar cancer. |
| AU2016324303A1 (en) * | 2015-09-18 | 2018-04-26 | The General Hospital Corporation Dba Massachusetts General Hospital | Modified T-cells having anti-fugetactic properties and uses thereof |
| CN109069486A (zh) | 2015-12-14 | 2018-12-21 | X4 制药有限公司 | 治疗癌症的方法 |
| CN109069426B (zh) * | 2015-12-14 | 2021-10-29 | X4 制药有限公司 | 治疗癌症的方法 |
| CA3014530A1 (en) | 2016-02-23 | 2017-08-31 | Biolinerx Ltd. | Methods of treating acute myeloid leukemia |
| US11337969B2 (en) | 2016-04-08 | 2022-05-24 | X4 Pharmaceuticals, Inc. | Methods for treating cancer |
| EP3808748B1 (en) | 2016-06-21 | 2026-05-20 | X4 Pharmaceuticals, Inc. | Substituted piperidines as cxcr4-inhibitors |
| JP6994767B2 (ja) | 2016-06-21 | 2022-01-14 | エックス4 ファーマシューティカルズ, インコーポレイテッド | Cxcr4阻害剤およびその使用 |
| US10988465B2 (en) | 2016-06-21 | 2021-04-27 | X4 Pharmaceuticals, Inc. | CXCR4 inhibitors and uses thereof |
| CA3066778A1 (en) * | 2017-06-21 | 2018-12-27 | X4 Pharmaceuticals, Inc. | Methods for treating cancer |
| US10548889B1 (en) | 2018-08-31 | 2020-02-04 | X4 Pharmaceuticals, Inc. | Compositions of CXCR4 inhibitors and methods of preparation and use |
| WO2020065647A1 (en) | 2018-09-25 | 2020-04-02 | Biolinerx Ltd. | Methods of selecting treatment for cxcr4-associated cancer |
| CN115515585A (zh) | 2020-03-10 | 2022-12-23 | X4 制药有限公司 | 用于治疗中性粒细胞减少症的方法 |
| TWI781469B (zh) * | 2020-10-27 | 2022-10-21 | 行政院原子能委員會核能研究所 | 複合物、造影劑及治療與cxcr4接受體相關疾病的用途 |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4005204A (en) * | 1973-03-23 | 1977-01-25 | Burroughs Wellcome Co. | Treatment of neoplasms in the brain with diamino dichloroalkyl pyrimidine |
| US5021409A (en) | 1989-12-21 | 1991-06-04 | Johnson Matthey Plc | Antiviral cyclic polyamines |
| US6001826A (en) * | 1989-12-21 | 1999-12-14 | Anormed, Inc. | Chemical compounds |
| GB9105489D0 (en) | 1991-03-15 | 1991-05-01 | Johnson Matthey Plc | Improvements in chemical compounds |
| GB9126677D0 (en) * | 1991-12-16 | 1992-02-12 | Johnson Matthey Plc | Improvements in chemical compounds |
| GB9400411D0 (en) * | 1994-01-11 | 1994-03-09 | Johnson Matthey Plc | Improvements in chemical compounds |
| GB9511357D0 (en) * | 1995-06-06 | 1995-08-02 | Johnson Matthey Plc | Improved antiviral compounds |
| US6506770B1 (en) * | 1996-06-06 | 2003-01-14 | Anormed, Inc. | Antiviral compounds |
| CA2305787A1 (en) * | 2000-05-09 | 2001-11-09 | The University Of British Columbia | Cxcr4 antagonist treatment of hematopoietic cells |
| IL145401A0 (en) | 1999-03-24 | 2002-06-30 | Anormed Inc | Chemokine receptor binding heterocyclic compounds |
| EP1244648B1 (en) * | 1999-12-17 | 2009-04-15 | Genzyme Corporation | Chemokine receptor binding heterocyclic compounds |
| KR20030034184A (ko) | 2000-09-15 | 2003-05-01 | 아노르메드 인코포레이티드 | 케모킨 수용체 결합 헤테로사이클릭 화합물 |
| NZ524421A (en) | 2000-09-15 | 2005-02-25 | Anormed Inc | Chemokine receptor binding heterocyclic compounds |
| RU2289581C2 (ru) | 2000-09-15 | 2006-12-20 | Анормед, Инк. | Гетероциклические соединения, содержащая их фармацевтическая композиция и их применение |
| EP1351678A2 (en) * | 2001-01-02 | 2003-10-15 | Elizabeth Shanahan-Prendergast | Treatment for inhibiting neoplastic lesions using incensole and/or furanogermacrens |
| CA2431611A1 (en) | 2001-01-23 | 2002-08-01 | P&G-Clairol, Inc. | Primary intermediates for oxidative coloration of hair |
| CN102302493B (zh) * | 2001-07-31 | 2015-08-12 | 健赞股份有限公司 | 活化祖细胞/干细胞的方法 |
| US7169750B2 (en) * | 2001-07-31 | 2007-01-30 | Anormed, Inc. | Methods to mobilize progenitor/stem cells |
| CA2467718C (en) * | 2001-12-21 | 2011-04-26 | Anormed Inc. | Chemokine receptor binding heterocyclic compounds with enhanced efficacy |
| EP1608318A4 (en) | 2003-03-27 | 2009-07-29 | Univ Emory | CXCR4 ANTAGONISTS AND METHOD OF USE |
| US20040202935A1 (en) | 2003-04-08 | 2004-10-14 | Jeremy Barker | Cathode active material with increased alkali/metal content and method of making same |
| CA2520259A1 (en) | 2003-04-11 | 2004-10-28 | Anormed Inc. | Cxcr4 chemokine receptor binding compounds |
| WO2005082415A2 (en) * | 2004-02-25 | 2005-09-09 | Dana Farber Cancer Institute, Inc. | Inhibitors of insulin-like growth factor receptor-1 for inhibiting tumor cell growth |
| JP2008509928A (ja) * | 2004-08-13 | 2008-04-03 | アノーメド インコーポレイテッド | 前駆/幹細胞を動員するためのケモカインの組み合わせ |
| US8569280B2 (en) * | 2005-04-25 | 2013-10-29 | Immune Disease Institute | Methods for the treatment of multiple myeloma |
| US7825088B2 (en) * | 2005-04-25 | 2010-11-02 | The Cbr Institute For Biomedical Research, Inc. | Methods for the treatment of multiple myeloma |
| AU2006340074A1 (en) * | 2006-02-24 | 2007-09-20 | Genzyme Corporation | Methods for increasing blood flow and/or promoting tissue regeneration |
-
2006
- 2006-08-21 US US11/507,717 patent/US20070043012A1/en not_active Abandoned
- 2006-08-21 EP EP06813613A patent/EP1951046B1/en not_active Revoked
- 2006-08-21 BR BRPI0615180-9A patent/BRPI0615180A2/pt not_active IP Right Cessation
- 2006-08-21 CA CA002619828A patent/CA2619828A1/en not_active Abandoned
- 2006-08-21 JP JP2008527219A patent/JP2009504788A/ja active Pending
- 2006-08-21 CN CN2006800350846A patent/CN101365336B/zh not_active Expired - Fee Related
- 2006-08-21 AU AU2006280945A patent/AU2006280945A1/en not_active Abandoned
- 2006-08-21 WO PCT/US2006/032668 patent/WO2007022523A2/en not_active Ceased
-
2008
- 2008-02-18 IL IL189599A patent/IL189599A0/en unknown
-
2013
- 2013-03-07 JP JP2013045053A patent/JP2013107903A/ja active Pending
- 2013-08-16 JP JP2013169087A patent/JP2013231086A/ja active Pending
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