BRPI0615180A2 - método para intensificar a quimioterapia - Google Patents
método para intensificar a quimioterapia Download PDFInfo
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- BRPI0615180A2 BRPI0615180A2 BRPI0615180-9A BRPI0615180A BRPI0615180A2 BR PI0615180 A2 BRPI0615180 A2 BR PI0615180A2 BR PI0615180 A BRPI0615180 A BR PI0615180A BR PI0615180 A2 BRPI0615180 A2 BR PI0615180A2
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- Prior art keywords
- formula
- ring
- optionally substituted
- alkyl
- substituted
- Prior art date
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- 238000000034 method Methods 0.000 title claims abstract description 64
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Landscapes
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| US8926990B2 (en) | 2009-10-13 | 2015-01-06 | Rutgers, The State University Of New Jersey | Treatment and diagnosis of inflammatory disorders and HIV |
| EP3011961B1 (en) * | 2006-12-21 | 2020-11-11 | Biokine Therapeutics LTD. | 4f-benzoyl-tn14003 for the mobilisation of hematopoietic progenitor cells in view of transplantation |
| WO2008109076A1 (en) * | 2007-03-02 | 2008-09-12 | Oxigene, Inc. | Methods for enhancing the efficacy of vascular disrupting agents |
| JP2012516353A (ja) * | 2009-01-30 | 2012-07-19 | ジェンザイム・コーポレーション | 血液系悪性腫瘍を治療するための方法及び組成物 |
| US9427456B2 (en) | 2009-06-14 | 2016-08-30 | Biokine Therapeutics Ltd. | Peptide therapy for increasing platelet levels |
| US20110207814A1 (en) * | 2009-12-23 | 2011-08-25 | Pranela Rameshwar | Combination Therapy for Breast Cancer Treatment |
| SG188220A1 (en) * | 2010-09-09 | 2013-04-30 | Noxxon Pharma Ag | Sdf-1 binding nucleic acids and the use thereof in cancer treatment |
| RU2638802C2 (ru) | 2011-05-16 | 2017-12-15 | Джензим Корпорейшн | Применение антагонистов cxcr4 |
| WO2013160895A1 (en) | 2012-04-24 | 2013-10-31 | Biokine Therapeutics Ltd. | Peptides and use thereof in the treatment of large cell lung cancer |
| CN105163749B (zh) | 2013-03-24 | 2018-03-27 | 拜欧肯治疗有限公司 | 治疗骨髓性白血病的方法 |
| EP3062809B1 (en) | 2013-10-31 | 2020-07-08 | Biokine Therapeutics Ltd. | A cxcr4 peptide inhibitor for use in treating acute myeloid leukemia with a flt3 mutation |
| JP2017508005A (ja) * | 2014-02-19 | 2017-03-23 | マイクロコンスタンツ チャイナ インク | ケモカイン受容体アンタゴニストおよびその併用療法 |
| KR101759688B1 (ko) * | 2015-01-16 | 2017-07-20 | 서울대학교산학협력단 | 사이클램 유도체 화합물 및 이의 약학적 용도 |
| WO2016114634A2 (ko) * | 2015-01-16 | 2016-07-21 | 서울대학교 산학협력단 | 사이클램 유도체 화합물 및 이의 약학적 용도 |
| MX2017013668A (es) * | 2015-04-25 | 2018-07-06 | Massachusetts Gen Hospital | Terapia de combinacion de agente anti-fuctactico y agente anti-cancer y composiciones para el tratamiento de cancer. |
| WO2016191811A1 (en) | 2015-06-03 | 2016-12-08 | The University Of Queensland | Mobilizing agents and uses therefor |
| MX2017016844A (es) | 2015-07-16 | 2018-08-15 | Biokine Therapeutics Ltd | Composiciones y procedimientos para tratar cancer. |
| AU2016324303A1 (en) * | 2015-09-18 | 2018-04-26 | The General Hospital Corporation Dba Massachusetts General Hospital | Modified T-cells having anti-fugetactic properties and uses thereof |
| CN109069486A (zh) | 2015-12-14 | 2018-12-21 | X4 制药有限公司 | 治疗癌症的方法 |
| CN109069426B (zh) * | 2015-12-14 | 2021-10-29 | X4 制药有限公司 | 治疗癌症的方法 |
| CA3014530A1 (en) | 2016-02-23 | 2017-08-31 | Biolinerx Ltd. | Methods of treating acute myeloid leukemia |
| US11337969B2 (en) | 2016-04-08 | 2022-05-24 | X4 Pharmaceuticals, Inc. | Methods for treating cancer |
| EP3808748B1 (en) | 2016-06-21 | 2026-05-20 | X4 Pharmaceuticals, Inc. | Substituted piperidines as cxcr4-inhibitors |
| JP6994767B2 (ja) | 2016-06-21 | 2022-01-14 | エックス４ ファーマシューティカルズ， インコーポレイテッド | Ｃｘｃｒ４阻害剤およびその使用 |
| US10988465B2 (en) | 2016-06-21 | 2021-04-27 | X4 Pharmaceuticals, Inc. | CXCR4 inhibitors and uses thereof |
| CA3066778A1 (en) * | 2017-06-21 | 2018-12-27 | X4 Pharmaceuticals, Inc. | Methods for treating cancer |
| US10548889B1 (en) | 2018-08-31 | 2020-02-04 | X4 Pharmaceuticals, Inc. | Compositions of CXCR4 inhibitors and methods of preparation and use |
| WO2020065647A1 (en) | 2018-09-25 | 2020-04-02 | Biolinerx Ltd. | Methods of selecting treatment for cxcr4-associated cancer |
| CN115515585A (zh) | 2020-03-10 | 2022-12-23 | X4 制药有限公司 | 用于治疗中性粒细胞减少症的方法 |
| TWI781469B (zh) * | 2020-10-27 | 2022-10-21 | 行政院原子能委員會核能研究所 | 複合物、造影劑及治療與cxcr4接受體相關疾病的用途 |
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| GB9105489D0 (en) | 1991-03-15 | 1991-05-01 | Johnson Matthey Plc | Improvements in chemical compounds |
| GB9126677D0 (en) * | 1991-12-16 | 1992-02-12 | Johnson Matthey Plc | Improvements in chemical compounds |
| GB9400411D0 (en) * | 1994-01-11 | 1994-03-09 | Johnson Matthey Plc | Improvements in chemical compounds |
| GB9511357D0 (en) * | 1995-06-06 | 1995-08-02 | Johnson Matthey Plc | Improved antiviral compounds |
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| EP1351678A2 (en) * | 2001-01-02 | 2003-10-15 | Elizabeth Shanahan-Prendergast | Treatment for inhibiting neoplastic lesions using incensole and/or furanogermacrens |
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| CN102302493B (zh) * | 2001-07-31 | 2015-08-12 | 健赞股份有限公司 | 活化祖细胞/干细胞的方法 |
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| US8569280B2 (en) * | 2005-04-25 | 2013-10-29 | Immune Disease Institute | Methods for the treatment of multiple myeloma |
| US7825088B2 (en) * | 2005-04-25 | 2010-11-02 | The Cbr Institute For Biomedical Research, Inc. | Methods for the treatment of multiple myeloma |
| AU2006340074A1 (en) * | 2006-02-24 | 2007-09-20 | Genzyme Corporation | Methods for increasing blood flow and/or promoting tissue regeneration |
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Also Published As
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| EP1951046A4 (en) | 2010-03-17 |
| CN101365336B (zh) | 2013-05-29 |
| AU2006280945A1 (en) | 2007-02-22 |
| US20070043012A1 (en) | 2007-02-22 |
| EP1951046A2 (en) | 2008-08-06 |
| WO2007022523A2 (en) | 2007-02-22 |
| JP2009504788A (ja) | 2009-02-05 |
| IL189599A0 (en) | 2008-08-07 |
| CA2619828A1 (en) | 2007-02-22 |
| JP2013107903A (ja) | 2013-06-06 |
| CN101365336A (zh) | 2009-02-11 |
| WO2007022523A3 (en) | 2007-11-22 |
| JP2013231086A (ja) | 2013-11-14 |
| EP1951046B1 (en) | 2012-07-18 |
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