JP2013047269A5 - - Google Patents
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- Publication number
- JP2013047269A5 JP2013047269A5 JP2012253067A JP2012253067A JP2013047269A5 JP 2013047269 A5 JP2013047269 A5 JP 2013047269A5 JP 2012253067 A JP2012253067 A JP 2012253067A JP 2012253067 A JP2012253067 A JP 2012253067A JP 2013047269 A5 JP2013047269 A5 JP 2013047269A5
- Authority
- JP
- Japan
- Prior art keywords
- bleeding
- estradiol
- daily doses
- days
- dysfunctional uterine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- VOXZDWNPVJITMN-ZBRFXRBCSA-N 17β-estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 VOXZDWNPVJITMN-ZBRFXRBCSA-N 0.000 description 7
- 206010013908 Dysfunctional uterine bleeding Diseases 0.000 description 7
- 208000032843 Hemorrhage Diseases 0.000 description 7
- 206010027514 Metrorrhagia Diseases 0.000 description 7
- 230000000740 bleeding effect Effects 0.000 description 7
- 229960005309 estradiol Drugs 0.000 description 7
- 229930182833 estradiol Natural products 0.000 description 7
- RSEPBGGWRJCQGY-RBRWEJTLSA-N Estradiol valerate Chemical compound C1CC2=CC(O)=CC=C2[C@@H]2[C@@H]1[C@@H]1CC[C@H](OC(=O)CCCC)[C@@]1(C)CC2 RSEPBGGWRJCQGY-RBRWEJTLSA-N 0.000 description 5
- 229960004766 estradiol valerate Drugs 0.000 description 5
- AZFLJNIPTRTECV-FUMNGEBKSA-N dienogest Chemical compound C1CC(=O)C=C2CC[C@@H]([C@H]3[C@@](C)([C@](CC3)(O)CC#N)CC3)C3=C21 AZFLJNIPTRTECV-FUMNGEBKSA-N 0.000 description 4
- 229960003309 dienogest Drugs 0.000 description 4
- 239000000902 placebo Substances 0.000 description 3
- 229940068196 placebo Drugs 0.000 description 3
- 239000000890 drug combination Substances 0.000 description 2
- 230000002045 lasting effect Effects 0.000 description 2
- 230000002175 menstrual effect Effects 0.000 description 2
- 230000003821 menstrual periods Effects 0.000 description 2
- 230000028327 secretion Effects 0.000 description 2
- BMUDPLZKKRQECS-UHFFFAOYSA-K 3-[18-(2-carboxyethyl)-8,13-bis(ethenyl)-3,7,12,17-tetramethylporphyrin-21,24-diid-2-yl]propanoic acid iron(3+) hydroxide Chemical compound [OH-].[Fe+3].[N-]1C2=C(C)C(CCC(O)=O)=C1C=C([N-]1)C(CCC(O)=O)=C(C)C1=CC(C(C)=C1C=C)=NC1=CC(C(C)=C1C=C)=NC1=C2 BMUDPLZKKRQECS-UHFFFAOYSA-K 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 208000037062 Polyps Diseases 0.000 description 1
- 206010046788 Uterine haemorrhage Diseases 0.000 description 1
- 206010046798 Uterine leiomyoma Diseases 0.000 description 1
- 230000005856 abnormality Effects 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 239000003433 contraceptive agent Substances 0.000 description 1
- 230000002254 contraceptive effect Effects 0.000 description 1
- 229940083543 estradiol 1 mg Drugs 0.000 description 1
- 230000007717 exclusion Effects 0.000 description 1
- 229940109738 hematin Drugs 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 201000010260 leiomyoma Diseases 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000027758 ovulation cycle Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05022324A EP1787649B1 (de) | 2005-10-13 | 2005-10-13 | Verwendung von Estradiolvalerat in Kombination mit Dienogest zur oralen Therapie der dysfunktionellen uterinen Blutung in Einheit mit einer oralen Kontrazeption |
| EP05022324.7 | 2005-10-13 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008534936A Division JP5735200B2 (ja) | 2005-10-13 | 2006-10-12 | 経口避妊薬の形での機能不全子宮出血の経口治療のためへの吉草酸エストラジオール又はエストラジオールとジエノゲストとの使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013047269A JP2013047269A (ja) | 2013-03-07 |
| JP2013047269A5 true JP2013047269A5 (https=) | 2014-10-02 |
Family
ID=35811580
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008534936A Active JP5735200B2 (ja) | 2005-10-13 | 2006-10-12 | 経口避妊薬の形での機能不全子宮出血の経口治療のためへの吉草酸エストラジオール又はエストラジオールとジエノゲストとの使用 |
| JP2012253067A Pending JP2013047269A (ja) | 2005-10-13 | 2012-11-19 | 経口避妊薬の形での機能不全子宮出血の経口治療のためへの吉草酸エストラジオール又はエストラジオールとジエノゲストとの使用 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008534936A Active JP5735200B2 (ja) | 2005-10-13 | 2006-10-12 | 経口避妊薬の形での機能不全子宮出血の経口治療のためへの吉草酸エストラジオール又はエストラジオールとジエノゲストとの使用 |
Country Status (22)
| Country | Link |
|---|---|
| EP (2) | EP1787649B1 (https=) |
| JP (2) | JP5735200B2 (https=) |
| KR (2) | KR101218872B1 (https=) |
| CN (1) | CN101312733A (https=) |
| AR (1) | AR056694A1 (https=) |
| AT (2) | ATE424828T1 (https=) |
| CA (1) | CA2623024C (https=) |
| CL (1) | CL2011000283A1 (https=) |
| CY (2) | CY1110321T1 (https=) |
| DE (2) | DE502005006837D1 (https=) |
| DK (2) | DK1787649T3 (https=) |
| DO (1) | DOP2006000221A (https=) |
| ES (2) | ES2322479T3 (https=) |
| HR (1) | HRP20090256T1 (https=) |
| ME (1) | ME01056B (https=) |
| PE (2) | PE20100090A1 (https=) |
| PL (2) | PL1787649T3 (https=) |
| PT (2) | PT1787649E (https=) |
| SI (2) | SI1787649T1 (https=) |
| TW (2) | TWI328453B (https=) |
| UY (1) | UY29861A1 (https=) |
| WO (1) | WO2007042296A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102004019743B4 (de) | 2004-04-20 | 2008-11-27 | Bayer Schering Pharma Aktiengesellschaft | Mehrphasenpräparat zur Kontrazeption auf der Basis eines natürlichen Estrogens |
| SI1787649T1 (sl) * | 2005-10-13 | 2009-08-31 | Bayer Schering Pharma Ag | Uporaba estradiolvalerata v kombinaciji z dienogestom za oralno terapijo disfunkcionalne maternične krvavitve skupaj z oralno kontracepcijo |
| US8153616B2 (en) | 2005-10-17 | 2012-04-10 | Bayer Pharma Aktiengesellschaft | Combination preparation for oral contraception and oral therapy of dysfunctional uterine bleeding containing estradiol valerate and dienogest and method of using same |
| EP1930010A1 (de) | 2006-10-20 | 2008-06-11 | Bayer Schering Pharma Aktiengesellschaft | Verwendung von Estradiolvalerat oder 17ß-Estradiol in Kombination mit Dienogest zur oralen Therapie für den Erhalt und/oder die Steigerung der weiblichen Libido |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4429374C1 (de) * | 1994-08-12 | 1996-02-01 | Jenapharm Gmbh | Pharmazeutische Präparate zur Kontrazeption/Hormonsubstitution mit biogener Estrogenkomponente |
| DE19540253C2 (de) * | 1995-10-28 | 1998-06-04 | Jenapharm Gmbh | Mehrphasenpräparat zur Kontrazeption auf der Basis natürlicher Estrogene |
| ATE249222T1 (de) * | 1996-07-26 | 2003-09-15 | Wyeth Corp | Biphasische orale verhuetungsmethode und kit die eine kombination von progestin und eines oestrogens enthalten |
| US6251956B1 (en) | 1998-08-20 | 2001-06-26 | Ortho Pharmaceutical Corporation | Combination progestin oral contraceptive regimen |
| EP1462106A1 (en) * | 2003-03-28 | 2004-09-29 | Pantarhei Bioscience B.V. | Pharmaceutical compositions and kits comprising 17-beta-estradiol and a progesteron for the treatment of gynecological disorders |
| DE102004019743B4 (de) * | 2004-04-20 | 2008-11-27 | Bayer Schering Pharma Aktiengesellschaft | Mehrphasenpräparat zur Kontrazeption auf der Basis eines natürlichen Estrogens |
| SI1787649T1 (sl) * | 2005-10-13 | 2009-08-31 | Bayer Schering Pharma Ag | Uporaba estradiolvalerata v kombinaciji z dienogestom za oralno terapijo disfunkcionalne maternične krvavitve skupaj z oralno kontracepcijo |
-
2005
- 2005-10-13 SI SI200530672T patent/SI1787649T1/sl unknown
- 2005-10-13 PT PT05022324T patent/PT1787649E/pt unknown
- 2005-10-13 ES ES05022324T patent/ES2322479T3/es not_active Expired - Lifetime
- 2005-10-13 EP EP05022324A patent/EP1787649B1/de not_active Revoked
- 2005-10-13 ME MEP-2009-171A patent/ME01056B/me unknown
- 2005-10-13 AT AT05022324T patent/ATE424828T1/de active
- 2005-10-13 DE DE502005006837T patent/DE502005006837D1/de not_active Expired - Lifetime
- 2005-10-13 PL PL05022324T patent/PL1787649T3/pl unknown
- 2005-10-13 DK DK05022324T patent/DK1787649T3/da active
-
2006
- 2006-10-12 PL PL06806225T patent/PL1933843T3/pl unknown
- 2006-10-12 SI SI200630991T patent/SI1933843T1/sl unknown
- 2006-10-12 JP JP2008534936A patent/JP5735200B2/ja active Active
- 2006-10-12 KR KR1020107014574A patent/KR101218872B1/ko active Active
- 2006-10-12 CN CNA2006800381810A patent/CN101312733A/zh active Pending
- 2006-10-12 KR KR1020087011203A patent/KR20080065651A/ko not_active Ceased
- 2006-10-12 EP EP06806225A patent/EP1933843B1/de active Active
- 2006-10-12 DK DK06806225.6T patent/DK1933843T3/da active
- 2006-10-12 WO PCT/EP2006/009867 patent/WO2007042296A1/de not_active Ceased
- 2006-10-12 DE DE502006008853T patent/DE502006008853D1/de active Active
- 2006-10-12 PE PE2009001256A patent/PE20100090A1/es not_active Application Discontinuation
- 2006-10-12 PE PE2006001241A patent/PE20070555A1/es not_active Application Discontinuation
- 2006-10-12 CA CA2623024A patent/CA2623024C/en active Active
- 2006-10-12 TW TW095137564A patent/TWI328453B/zh active
- 2006-10-12 AT AT06806225T patent/ATE497387T1/de active
- 2006-10-12 ES ES06806225T patent/ES2360302T3/es active Active
- 2006-10-12 PT PT06806225T patent/PT1933843E/pt unknown
- 2006-10-13 DO DO2006000221A patent/DOP2006000221A/es unknown
- 2006-10-13 AR ARP060104489A patent/AR056694A1/es not_active Application Discontinuation
- 2006-10-13 UY UY29861A patent/UY29861A1/es not_active Application Discontinuation
-
2007
- 2007-01-09 TW TW096100872A patent/TW200829255A/zh unknown
-
2009
- 2009-05-05 HR HR20090256T patent/HRP20090256T1/xx unknown
- 2009-06-11 CY CY20091100621T patent/CY1110321T1/el unknown
-
2011
- 2011-02-10 CL CL2011000283A patent/CL2011000283A1/es unknown
- 2011-05-02 CY CY20111100422T patent/CY1111406T1/el unknown
-
2012
- 2012-11-19 JP JP2012253067A patent/JP2013047269A/ja active Pending
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