JP2012533407A5 - - Google Patents
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- Publication number
- JP2012533407A5 JP2012533407A5 JP2012521677A JP2012521677A JP2012533407A5 JP 2012533407 A5 JP2012533407 A5 JP 2012533407A5 JP 2012521677 A JP2012521677 A JP 2012521677A JP 2012521677 A JP2012521677 A JP 2012521677A JP 2012533407 A5 JP2012533407 A5 JP 2012533407A5
- Authority
- JP
- Japan
- Prior art keywords
- copolymer
- glycolide
- lactide
- mol
- poly
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229920001577 copolymer Polymers 0.000 claims 16
- RKDVKSZUMVYZHH-UHFFFAOYSA-N 1,4-dioxane-2,5-dione Chemical compound O=C1COC(=O)CO1 RKDVKSZUMVYZHH-UHFFFAOYSA-N 0.000 claims 6
- 239000002667 nucleating agent Substances 0.000 claims 4
- 238000000034 method Methods 0.000 claims 3
- JJTUDXZGHPGLLC-IMJSIDKUSA-N 4511-42-6 Chemical compound C[C@@H]1OC(=O)[C@H](C)OC1=O JJTUDXZGHPGLLC-IMJSIDKUSA-N 0.000 claims 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims 2
- 238000000137 annealing Methods 0.000 claims 2
- YCIMNLLNPGFGHC-UHFFFAOYSA-N catechol Chemical compound OC1=CC=CC=C1O YCIMNLLNPGFGHC-UHFFFAOYSA-N 0.000 claims 2
- LZCLXQDLBQLTDK-UHFFFAOYSA-N ethyl 2-hydroxypropanoate Chemical compound CCOC(=O)C(C)O LZCLXQDLBQLTDK-UHFFFAOYSA-N 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 229920000642 polymer Polymers 0.000 claims 2
- KMZHZAAOEWVPSE-UHFFFAOYSA-N 2,3-dihydroxypropyl acetate Chemical compound CC(=O)OCC(O)CO KMZHZAAOEWVPSE-UHFFFAOYSA-N 0.000 claims 1
- MQIUGAXCHLFZKX-UHFFFAOYSA-N Di-n-octyl phthalate Natural products CCCCCCCCOC(=O)C1=CC=CC=C1C(=O)OCCCCCCCC MQIUGAXCHLFZKX-UHFFFAOYSA-N 0.000 claims 1
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 claims 1
- 239000005977 Ethylene Substances 0.000 claims 1
- UYXTWWCETRIEDR-UHFFFAOYSA-N Tributyrin Chemical compound CCCC(=O)OCC(OC(=O)CCC)COC(=O)CCC UYXTWWCETRIEDR-UHFFFAOYSA-N 0.000 claims 1
- WURBFLDFSFBTLW-UHFFFAOYSA-N benzil Chemical group C=1C=CC=CC=1C(=O)C(=O)C1=CC=CC=C1 WURBFLDFSFBTLW-UHFFFAOYSA-N 0.000 claims 1
- BJQHLKABXJIVAM-UHFFFAOYSA-N bis(2-ethylhexyl) phthalate Chemical compound CCCCC(CC)COC(=O)C1=CC=CC=C1C(=O)OCC(CC)CCCC BJQHLKABXJIVAM-UHFFFAOYSA-N 0.000 claims 1
- -1 citrate ester Chemical class 0.000 claims 1
- 235000014113 dietary fatty acids Nutrition 0.000 claims 1
- DGVMNQYBHPSIJS-UHFFFAOYSA-N dimagnesium;2,2,6,6-tetraoxido-1,3,5,7-tetraoxa-2,4,6-trisilaspiro[3.3]heptane;hydrate Chemical compound O.[Mg+2].[Mg+2].O1[Si]([O-])([O-])O[Si]21O[Si]([O-])([O-])O2 DGVMNQYBHPSIJS-UHFFFAOYSA-N 0.000 claims 1
- GRGBENNNGZARRZ-UHFFFAOYSA-N dodecanedihydrazide Chemical compound NNC(=O)CCCCCCCCCCC(=O)NN GRGBENNNGZARRZ-UHFFFAOYSA-N 0.000 claims 1
- 229940116333 ethyl lactate Drugs 0.000 claims 1
- 239000000194 fatty acid Substances 0.000 claims 1
- 229930195729 fatty acid Natural products 0.000 claims 1
- 150000004665 fatty acids Chemical class 0.000 claims 1
- 235000011187 glycerol Nutrition 0.000 claims 1
- 229910052588 hydroxylapatite Inorganic materials 0.000 claims 1
- 150000003903 lactic acid esters Chemical class 0.000 claims 1
- JJTUDXZGHPGLLC-UHFFFAOYSA-N lactide Chemical class CC1OC(=O)C(C)OC1=O JJTUDXZGHPGLLC-UHFFFAOYSA-N 0.000 claims 1
- 239000000155 melt Substances 0.000 claims 1
- 239000000178 monomer Substances 0.000 claims 1
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 claims 1
- 239000000454 talc Substances 0.000 claims 1
- 229910052623 talc Inorganic materials 0.000 claims 1
- XZZNDPSIHUTMOC-UHFFFAOYSA-N triphenyl phosphate Chemical compound C=1C=CC=CC=1OP(OC=1C=CC=CC=1)(=O)OC1=CC=CC=C1 XZZNDPSIHUTMOC-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12/506,881 US8119704B2 (en) | 2009-07-21 | 2009-07-21 | Implantable medical device comprising copolymer of L-lactide with improved fracture toughness |
| US12/506,881 | 2009-07-21 | ||
| PCT/US2010/041996 WO2011011241A2 (en) | 2009-07-21 | 2010-07-14 | Implantable medical device comprising copolymer of l-lactide with improved fracture toughness |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012533407A JP2012533407A (ja) | 2012-12-27 |
| JP2012533407A5 true JP2012533407A5 (enExample) | 2013-08-29 |
Family
ID=42731899
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012521677A Pending JP2012533407A (ja) | 2009-07-21 | 2010-07-14 | L−ラクチドのコポリマーを含む破壊靱性を改良した埋込型医療機器 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US8119704B2 (enExample) |
| EP (1) | EP2456479B1 (enExample) |
| JP (1) | JP2012533407A (enExample) |
| WO (1) | WO2011011241A2 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8486135B2 (en) | 2006-06-01 | 2013-07-16 | Abbott Cardiovascular Systems Inc. | Implantable medical devices fabricated from branched polymers |
| US8952123B1 (en) * | 2006-08-02 | 2015-02-10 | Abbott Cardiovascular Systems Inc. | Dioxanone-based copolymers for implantable devices |
| US20130150943A1 (en) * | 2007-01-19 | 2013-06-13 | Elixir Medical Corporation | Biodegradable endoprostheses and methods for their fabrication |
| US8814930B2 (en) * | 2007-01-19 | 2014-08-26 | Elixir Medical Corporation | Biodegradable endoprosthesis and methods for their fabrication |
| EP2367505B1 (en) | 2008-09-29 | 2020-08-12 | Edwards Lifesciences CardiAQ LLC | Heart valve |
| EP2845569A1 (en) | 2008-10-01 | 2015-03-11 | Cardiaq Valve Technologies, Inc. | Delivery system for vascular implant |
| WO2010121076A2 (en) | 2009-04-15 | 2010-10-21 | Cardiaq Valve Technologies, Inc. | Vascular implant and delivery system |
| US8579964B2 (en) | 2010-05-05 | 2013-11-12 | Neovasc Inc. | Transcatheter mitral valve prosthesis |
| US9308087B2 (en) | 2011-04-28 | 2016-04-12 | Neovasc Tiara Inc. | Sequentially deployed transcatheter mitral valve prosthesis |
| US9554897B2 (en) | 2011-04-28 | 2017-01-31 | Neovasc Tiara Inc. | Methods and apparatus for engaging a valve prosthesis with tissue |
| US8841412B2 (en) | 2011-08-11 | 2014-09-23 | Abbott Cardiovascular Systems Inc. | Controlling moisture in and plasticization of bioresorbable polymer for melt processing |
| KR101316069B1 (ko) | 2011-08-25 | 2013-10-11 | 한국과학기술연구원 | 유연한 폴리락티드 입체이성질 복합체의 제조방법 및 이의 방법에 의해 제조된 화합물 |
| US9345573B2 (en) | 2012-05-30 | 2016-05-24 | Neovasc Tiara Inc. | Methods and apparatus for loading a prosthesis onto a delivery system |
| US10583002B2 (en) | 2013-03-11 | 2020-03-10 | Neovasc Tiara Inc. | Prosthetic valve with anti-pivoting mechanism |
| US9681951B2 (en) | 2013-03-14 | 2017-06-20 | Edwards Lifesciences Cardiaq Llc | Prosthesis with outer skirt and anchors |
| US9572665B2 (en) | 2013-04-04 | 2017-02-21 | Neovasc Tiara Inc. | Methods and apparatus for delivering a prosthetic valve to a beating heart |
| CN103387756B (zh) * | 2013-07-30 | 2015-07-08 | 浙江微度医疗器械有限公司 | 一种羟基磷灰石的改性方法和应用 |
| US9480588B2 (en) | 2014-08-15 | 2016-11-01 | Elixir Medical Corporation | Biodegradable endoprostheses and methods of their fabrication |
| US9259339B1 (en) | 2014-08-15 | 2016-02-16 | Elixir Medical Corporation | Biodegradable endoprostheses and methods of their fabrication |
| US9730819B2 (en) | 2014-08-15 | 2017-08-15 | Elixir Medical Corporation | Biodegradable endoprostheses and methods of their fabrication |
| US9855156B2 (en) * | 2014-08-15 | 2018-01-02 | Elixir Medical Corporation | Biodegradable endoprostheses and methods of their fabrication |
| US11622872B2 (en) | 2016-05-16 | 2023-04-11 | Elixir Medical Corporation | Uncaging stent |
| ES2873887T3 (es) | 2016-05-16 | 2021-11-04 | Elixir Medical Corp | Liberación de stent |
| CN107011641A (zh) * | 2017-05-11 | 2017-08-04 | 广州飞胜高分子材料有限公司 | 一种用于3d打印的低温支架复合材料及其加工方法 |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE758156R (fr) * | 1970-05-13 | 1971-04-28 | Ethicon Inc | Element de suture absorbable et sa |
| US5085629A (en) * | 1988-10-06 | 1992-02-04 | Medical Engineering Corporation | Biodegradable stent |
| US6607548B2 (en) * | 2001-05-17 | 2003-08-19 | Inion Ltd. | Resorbable polymer compositions |
| US6747121B2 (en) * | 2001-09-05 | 2004-06-08 | Synthes (Usa) | Poly(L-lactide-co-glycolide) copolymers, methods for making and using same, and devices containing same |
| US7572287B2 (en) * | 2001-10-25 | 2009-08-11 | Boston Scientific Scimed, Inc. | Balloon expandable polymer stent with reduced elastic recoil |
| EP1764118B1 (en) * | 2002-02-15 | 2010-08-25 | Gilead Palo Alto, Inc. | Polymer coating for medical devices |
| WO2003099169A1 (en) * | 2002-05-20 | 2003-12-04 | Orbus Medical Technologies Inc. | Drug eluting implantable medical device |
| US6932930B2 (en) * | 2003-03-10 | 2005-08-23 | Synecor, Llc | Intraluminal prostheses having polymeric material with selectively modified crystallinity and methods of making same |
| US20050112170A1 (en) * | 2003-11-20 | 2005-05-26 | Hossainy Syed F. | Coatings for implantable devices comprising polymers of lactic acid and methods for fabricating the same |
| DE602004029094D1 (de) * | 2004-03-04 | 2010-10-21 | Unitika Ltd | Herstellungsverfahren dafür und schaumstoff und formkörper daraus |
| CN1942527B (zh) * | 2004-05-11 | 2010-12-01 | 花王株式会社 | 生物降解性树脂组合物 |
| US8778375B2 (en) * | 2005-04-29 | 2014-07-15 | Advanced Cardiovascular Systems, Inc. | Amorphous poly(D,L-lactide) coating |
| DE102005033101A1 (de) * | 2005-07-15 | 2007-01-25 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Resorbierbare Polyetherester und ihre Verwendung zur Herstellung von medizinischen Implantaten |
| JP4899152B2 (ja) * | 2005-07-15 | 2012-03-21 | 独立行政法人産業技術総合研究所 | 医療用樹脂組成物とその製造方法および成形体 |
| US20070132156A1 (en) * | 2005-12-13 | 2007-06-14 | Robert Burgermeister | Polymeric stent having modified molecular structures in selected regions of the hoops and method for making the same |
| US7842737B2 (en) * | 2006-09-29 | 2010-11-30 | Abbott Cardiovascular Systems Inc. | Polymer blend-bioceramic composite implantable medical devices |
| EP3009477B1 (en) * | 2006-07-20 | 2024-01-24 | Orbusneich Medical Pte. Ltd | Bioabsorbable polymeric composition for a medical device |
| WO2008011614A2 (en) * | 2006-07-20 | 2008-01-24 | Orbusneich Medical, Inc. | Bioabsorbable polymeric medical device |
| US8394488B2 (en) * | 2006-10-06 | 2013-03-12 | Cordis Corporation | Bioabsorbable device having composite structure for accelerating degradation |
| US8182890B2 (en) * | 2007-01-19 | 2012-05-22 | Elixir Medical Corporation | Biodegradable endoprostheses and methods for their fabrication |
| US7956100B2 (en) * | 2007-09-28 | 2011-06-07 | Abbott Cardiovascular Systems Inc. | Implantable medical devices fabricated from block copolymers |
| US8661630B2 (en) * | 2008-05-21 | 2014-03-04 | Abbott Cardiovascular Systems Inc. | Coating comprising an amorphous primer layer and a semi-crystalline reservoir layer |
| US20090104241A1 (en) * | 2007-10-23 | 2009-04-23 | Pacetti Stephen D | Random amorphous terpolymer containing lactide and glycolide |
| US20090111787A1 (en) * | 2007-10-31 | 2009-04-30 | Florencia Lim | Polymer blends for drug delivery stent matrix with improved thermal stability |
| US20090110713A1 (en) * | 2007-10-31 | 2009-04-30 | Florencia Lim | Biodegradable polymeric materials providing controlled release of hydrophobic drugs from implantable devices |
| US8916188B2 (en) * | 2008-04-18 | 2014-12-23 | Abbott Cardiovascular Systems Inc. | Block copolymer comprising at least one polyester block and a poly (ethylene glycol) block |
| US8951546B2 (en) * | 2008-12-23 | 2015-02-10 | Surmodics Pharmaceuticals, Inc. | Flexible implantable composites and implants comprising same |
| US8697110B2 (en) * | 2009-05-14 | 2014-04-15 | Abbott Cardiovascular Systems Inc. | Polymers comprising amorphous terpolymers and semicrystalline blocks |
-
2009
- 2009-07-21 US US12/506,881 patent/US8119704B2/en not_active Expired - Fee Related
-
2010
- 2010-07-14 WO PCT/US2010/041996 patent/WO2011011241A2/en not_active Ceased
- 2010-07-14 EP EP10733128.2A patent/EP2456479B1/en not_active Ceased
- 2010-07-14 JP JP2012521677A patent/JP2012533407A/ja active Pending
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