JP2012533354A5 - - Google Patents
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- JP2012533354A5 JP2012533354A5 JP2012520744A JP2012520744A JP2012533354A5 JP 2012533354 A5 JP2012533354 A5 JP 2012533354A5 JP 2012520744 A JP2012520744 A JP 2012520744A JP 2012520744 A JP2012520744 A JP 2012520744A JP 2012533354 A5 JP2012533354 A5 JP 2012533354A5
- Authority
- JP
- Japan
- Prior art keywords
- silk
- cells
- mat
- cell
- peo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000004027 cell Anatomy 0.000 claims 34
- 239000000463 material Substances 0.000 claims 22
- 239000013543 active substance Substances 0.000 claims 18
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims 17
- 238000000034 method Methods 0.000 claims 17
- 108010022355 Fibroins Proteins 0.000 claims 9
- 239000003814 drug Substances 0.000 claims 8
- 239000012634 fragment Substances 0.000 claims 8
- 239000003102 growth factor Substances 0.000 claims 8
- 108020004707 nucleic acids Proteins 0.000 claims 8
- 102000039446 nucleic acids Human genes 0.000 claims 8
- 150000007523 nucleic acids Chemical class 0.000 claims 8
- 102000004169 proteins and genes Human genes 0.000 claims 7
- 108090000623 proteins and genes Proteins 0.000 claims 7
- 239000003242 anti bacterial agent Substances 0.000 claims 6
- 230000005540 biological transmission Effects 0.000 claims 5
- 238000001523 electrospinning Methods 0.000 claims 5
- 239000000203 mixture Substances 0.000 claims 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 5
- 108091023037 Aptamer Proteins 0.000 claims 4
- 108090000695 Cytokines Proteins 0.000 claims 4
- 102000004127 Cytokines Human genes 0.000 claims 4
- 108090000790 Enzymes Proteins 0.000 claims 4
- 102000004190 Enzymes Human genes 0.000 claims 4
- 108091034117 Oligonucleotide Proteins 0.000 claims 4
- 108091093037 Peptide nucleic acid Proteins 0.000 claims 4
- 241000700605 Viruses Species 0.000 claims 4
- 230000000844 anti-bacterial effect Effects 0.000 claims 4
- 229940088710 antibiotic agent Drugs 0.000 claims 4
- 239000000427 antigen Substances 0.000 claims 4
- 108091007433 antigens Proteins 0.000 claims 4
- 102000036639 antigens Human genes 0.000 claims 4
- 239000002246 antineoplastic agent Substances 0.000 claims 4
- 239000012620 biological material Substances 0.000 claims 4
- 230000021164 cell adhesion Effects 0.000 claims 4
- 210000001612 chondrocyte Anatomy 0.000 claims 4
- 150000001875 compounds Chemical class 0.000 claims 4
- 229940127089 cytotoxic agent Drugs 0.000 claims 4
- 229940079593 drug Drugs 0.000 claims 4
- 210000002919 epithelial cell Anatomy 0.000 claims 4
- 239000005556 hormone Substances 0.000 claims 4
- 229940088597 hormone Drugs 0.000 claims 4
- 239000003667 hormone antagonist Substances 0.000 claims 4
- 239000002773 nucleotide Substances 0.000 claims 4
- 125000003729 nucleotide group Chemical group 0.000 claims 4
- 108090000765 processed proteins & peptides Proteins 0.000 claims 4
- 229940002612 prodrug Drugs 0.000 claims 4
- 239000000651 prodrug Substances 0.000 claims 4
- 150000003384 small molecules Chemical class 0.000 claims 4
- 210000000130 stem cell Anatomy 0.000 claims 4
- 229940124597 therapeutic agent Drugs 0.000 claims 4
- 239000003053 toxin Substances 0.000 claims 4
- 231100000765 toxin Toxicity 0.000 claims 4
- 108700012359 toxins Proteins 0.000 claims 4
- 206010052428 Wound Diseases 0.000 claims 3
- 208000027418 Wounds and injury Diseases 0.000 claims 3
- 238000010521 absorption reaction Methods 0.000 claims 3
- 239000007864 aqueous solution Substances 0.000 claims 3
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims 3
- 229910052760 oxygen Inorganic materials 0.000 claims 3
- 239000001301 oxygen Substances 0.000 claims 3
- 230000001737 promoting effect Effects 0.000 claims 3
- 230000029663 wound healing Effects 0.000 claims 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 2
- 210000001789 adipocyte Anatomy 0.000 claims 2
- 230000001919 adrenal effect Effects 0.000 claims 2
- 210000002469 basement membrane Anatomy 0.000 claims 2
- 210000000013 bile duct Anatomy 0.000 claims 2
- 230000003115 biocidal effect Effects 0.000 claims 2
- 210000003969 blast cell Anatomy 0.000 claims 2
- 210000000988 bone and bone Anatomy 0.000 claims 2
- 210000002798 bone marrow cell Anatomy 0.000 claims 2
- 210000004413 cardiac myocyte Anatomy 0.000 claims 2
- 230000010261 cell growth Effects 0.000 claims 2
- 210000002889 endothelial cell Anatomy 0.000 claims 2
- 210000002950 fibroblast Anatomy 0.000 claims 2
- 239000001963 growth medium Substances 0.000 claims 2
- 210000003494 hepatocyte Anatomy 0.000 claims 2
- 230000002267 hypothalamic effect Effects 0.000 claims 2
- 210000004153 islets of langerhan Anatomy 0.000 claims 2
- 210000002510 keratinocyte Anatomy 0.000 claims 2
- 210000003098 myoblast Anatomy 0.000 claims 2
- 210000002997 osteoclast Anatomy 0.000 claims 2
- 230000002611 ovarian Effects 0.000 claims 2
- 230000000849 parathyroid Effects 0.000 claims 2
- 230000001817 pituitary effect Effects 0.000 claims 2
- 239000011148 porous material Substances 0.000 claims 2
- 239000002243 precursor Substances 0.000 claims 2
- 210000003079 salivary gland Anatomy 0.000 claims 2
- 210000002363 skeletal muscle cell Anatomy 0.000 claims 2
- 210000000329 smooth muscle myocyte Anatomy 0.000 claims 2
- 210000001550 testis Anatomy 0.000 claims 2
- 210000001685 thyroid gland Anatomy 0.000 claims 2
- 238000001035 drying Methods 0.000 claims 1
- 230000005684 electric field Effects 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 230000000452 restraining effect Effects 0.000 claims 1
- 238000009987 spinning Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22533509P | 2009-07-14 | 2009-07-14 | |
| US61/225,335 | 2009-07-14 | ||
| PCT/US2010/041953 WO2011008842A2 (en) | 2009-07-14 | 2010-07-14 | Electrospun silk material systems for wound healing |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012533354A JP2012533354A (ja) | 2012-12-27 |
| JP2012533354A5 true JP2012533354A5 (cg-RX-API-DMAC7.html) | 2013-08-29 |
Family
ID=43450163
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012520744A Pending JP2012533354A (ja) | 2009-07-14 | 2010-07-14 | 創傷治癒のための電界紡糸絹材料システム |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8728498B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2453931A4 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2012533354A (cg-RX-API-DMAC7.html) |
| CA (1) | CA2812635A1 (cg-RX-API-DMAC7.html) |
| IL (1) | IL217464A0 (cg-RX-API-DMAC7.html) |
| IN (1) | IN2012DN00445A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2011008842A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (62)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1759422B1 (en) | 2004-06-04 | 2022-01-26 | The Board Of Trustees Of The University Of Illinois | Electrical device comprising printable semiconductor elements |
| AU2009302192B2 (en) | 2008-06-18 | 2014-08-28 | Trustees Of Tufts College | Modified silk films containing glycerol |
| US8886334B2 (en) | 2008-10-07 | 2014-11-11 | Mc10, Inc. | Systems, methods, and devices using stretchable or flexible electronics for medical applications |
| JP5646492B2 (ja) | 2008-10-07 | 2014-12-24 | エムシー１０ インコーポレイテッドＭｃ１０，Ｉｎｃ． | 伸縮可能な集積回路およびセンサアレイを有する装置 |
| US8389862B2 (en) | 2008-10-07 | 2013-03-05 | Mc10, Inc. | Extremely stretchable electronics |
| EP2483460B1 (en) | 2009-09-28 | 2015-09-02 | Trustees Of Tufts College | Method to prepare drawn silk egel fibers |
| WO2011041727A1 (en) | 2009-10-01 | 2011-04-07 | Mc10, Inc. | Protective cases with integrated electronics |
| US10441185B2 (en) | 2009-12-16 | 2019-10-15 | The Board Of Trustees Of The University Of Illinois | Flexible and stretchable electronic systems for epidermal electronics |
| US9936574B2 (en) | 2009-12-16 | 2018-04-03 | The Board Of Trustees Of The University Of Illinois | Waterproof stretchable optoelectronics |
| WO2011084450A1 (en) | 2009-12-16 | 2011-07-14 | The Board Of Trustees Of The University Of Illinois | Electrophysiology in-vivo using conformal electronics |
| KR101724273B1 (ko) | 2010-03-17 | 2017-04-07 | 더 보드 오브 트러스티즈 오브 더 유니버시티 오브 일리노이 | 생체흡수성 기판 상 이식가능한 바이오의료 장치 |
| CA2847590A1 (en) | 2010-09-03 | 2012-03-08 | Tufts University/Trustees Of Tufts College | Plasmonic nanoparticle-doped silk materials |
| GB2485384A (en) * | 2010-11-12 | 2012-05-16 | Ngee Ann Polytechnic | Porous fibre encapsulating biological material |
| WO2012158709A1 (en) | 2011-05-16 | 2012-11-22 | The Board Of Trustees Of The University Of Illinois | Thermally managed led arrays assembled by printing |
| EP2712491B1 (en) | 2011-05-27 | 2019-12-04 | Mc10, Inc. | Flexible electronic structure |
| EP2713863B1 (en) | 2011-06-03 | 2020-01-15 | The Board of Trustees of the University of Illionis | Conformable actively multiplexed high-density surface electrode array for brain interfacing |
| WO2013025819A2 (en) * | 2011-08-16 | 2013-02-21 | The University Of Kansas | Fibrous tracheal patch |
| US9691873B2 (en) | 2011-12-01 | 2017-06-27 | The Board Of Trustees Of The University Of Illinois | Transient devices designed to undergo programmable transformations |
| US10126467B2 (en) | 2011-12-05 | 2018-11-13 | Tufts University | Signal enhancement by silk photonic crystals |
| EP3884931A3 (en) * | 2012-02-06 | 2021-12-01 | Children's Medical Center, Corp. | Multi-layer biomaterial for tissue regeneration and wound healing |
| WO2013121186A1 (en) * | 2012-02-15 | 2013-08-22 | Archimed Llp | Wound screen |
| NL1039495C2 (nl) * | 2012-03-27 | 2013-09-30 | Jalila Essaidi | Werkwijze ter vervaardiging van een huidsubstituut op basis van spinnenzijde alsmede draagstructuur vervaardigd onder toepassing van deze werkwijze en draagstructuur met doorgroeiende levende huid. |
| KR20150004819A (ko) | 2012-03-30 | 2015-01-13 | 더 보오드 오브 트러스티스 오브 더 유니버시티 오브 일리노이즈 | 표면에 상응하는 부속체 장착가능한 전자 장치 |
| US9925301B2 (en) | 2012-04-06 | 2018-03-27 | Trustees Of Tufts College | Methods of producing and using silk microfibers |
| US10653786B2 (en) | 2012-04-25 | 2020-05-19 | Trustees Of Tufts College | Silk microspheres and methods for surface lubrication |
| US9171794B2 (en) | 2012-10-09 | 2015-10-27 | Mc10, Inc. | Embedding thin chips in polymer |
| CN103083224A (zh) * | 2013-02-06 | 2013-05-08 | 东华大学 | 一种地塞米松缓释型药物载体的制备方法 |
| US20160046679A1 (en) | 2013-03-15 | 2016-02-18 | Trustees Of Tufts College | Low molecular weight silk compositions and stabilizing silk compositions |
| US11376329B2 (en) | 2013-03-15 | 2022-07-05 | Trustees Of Tufts College | Low molecular weight silk compositions and stabilizing silk compositions |
| DE102013111322A1 (de) | 2013-05-03 | 2014-11-06 | Ars Arthro Bioteknoloji A.S. | Verfahren zur Herstellung von Hydrokolloid-Schwämmen |
| GB2514592A (en) * | 2013-05-30 | 2014-12-03 | Medtrade Products Ltd | Degradable haemostat composition |
| KR101573838B1 (ko) * | 2014-06-13 | 2015-12-07 | 대한민국 | 누에고치를 이용한 인공 생체막 및 이의 제조방법 |
| EP3182985B1 (en) | 2014-08-20 | 2020-01-08 | Silk Technologies Ltd. | Fibroin-derived protein composition |
| WO2016059611A1 (en) * | 2014-10-17 | 2016-04-21 | Leonardino S.R.L. | "device for wound dressing" |
| JP6946187B2 (ja) | 2014-12-02 | 2021-10-06 | エボルブド バイ ネイチャー， インコーポレイテッド | シルク性能衣服及び製品、並びにこれらを製造する方法 |
| MX2017015587A (es) | 2015-06-01 | 2018-08-23 | Univ Illinois | Metodo alternativo para sensor uv. |
| JP2018524677A (ja) | 2015-06-01 | 2018-08-30 | ザ ボード オブ トラスティーズ オブ ザ ユニヴァーシティー オブ イリノイ | 無線電力及び近距離無線通信機能を備えた小型電子システム |
| CA2992462A1 (en) | 2015-07-14 | 2017-01-19 | Silk Therapeutics, Inc. | Silk performance apparel and products and methods of preparing the same |
| JP6528278B2 (ja) * | 2015-09-24 | 2019-06-12 | 国立大学法人信州大学 | ナノファイバーの製造方法及びエレクトロスピニング用ドープ |
| KR101602791B1 (ko) * | 2015-10-21 | 2016-03-11 | 대한민국 | 평면견을 이용한 혈관용 패치 및 이의 제조방법 |
| US10925543B2 (en) | 2015-11-11 | 2021-02-23 | The Board Of Trustees Of The University Of Illinois | Bioresorbable silicon electronics for transient implants |
| KR101871781B1 (ko) * | 2016-01-18 | 2018-07-31 | 한림대학교 산학협력단 | 요소분해효소 고정화 불용성 다공성 지지체를 이용한 휴대형 요소 센서 모듈 |
| JP6656012B2 (ja) * | 2016-02-12 | 2020-03-04 | 株式会社豊和堂シルクテック | ナノポーラス構造を有するフィブロイン成形物の製造方法 |
| JP6656011B2 (ja) * | 2016-02-12 | 2020-03-04 | 株式会社豊和堂シルクテック | フィブロインナノファイバーの製造方法 |
| US10953132B2 (en) | 2016-04-08 | 2021-03-23 | Cornell University | Method to enhance wound healing using silk-derived protein |
| WO2018006037A1 (en) * | 2016-07-01 | 2018-01-04 | Trustees Of Tufts College | Innervated artificial skin |
| EP3496662A4 (en) | 2016-08-12 | 2019-10-30 | Silk Technologies Ltd. | SILICONE PROTEIN FOR THE TREATMENT OF IGNITION |
| US10517989B1 (en) | 2016-11-23 | 2019-12-31 | Jonathan F. Arnold | Enhanced medical dressing apparatus, system, and method |
| CN114870097B (zh) * | 2017-09-08 | 2024-04-09 | 宙斯有限公司 | 具有控制的取向的聚合物管 |
| US11390988B2 (en) | 2017-09-27 | 2022-07-19 | Evolved By Nature, Inc. | Silk coated fabrics and products and methods of preparing the same |
| JP2021152224A (ja) * | 2018-04-03 | 2021-09-30 | Ｓｐｉｂｅｒ株式会社 | 高密度不織布、及び高密度不織布の製造方法 |
| GB201903388D0 (en) * | 2019-03-12 | 2019-04-24 | Univ Manchester | Tissue repair scaffold and device |
| CN110031610B (zh) * | 2019-03-20 | 2024-08-27 | 广东工业大学 | 一种蚕茧双向透湿性的测试装置 |
| CN110448719B (zh) * | 2019-06-28 | 2020-05-22 | 浙江大学 | 一种促进凝血的丝素-多肽电纺膜及其制备方法 |
| NL2026464B1 (en) * | 2020-09-14 | 2022-05-16 | Umc Utrecht Holding Bv | A composition for electrowriting of viable cells |
| EP3981443A1 (en) | 2020-10-08 | 2022-04-13 | Johann Wolfgang Goethe-Universität Frankfurt | Improved wound dressings, methods for making these, and uses thereof |
| CN112301542A (zh) * | 2020-10-20 | 2021-02-02 | 福建农林大学 | 一种核壳型复合纳米纤维膜及其制备方法与应用 |
| US20220247559A1 (en) * | 2021-02-03 | 2022-08-04 | Gwangju Institute Of Science And Technology | Puf id and puf id reader |
| CN113604958A (zh) * | 2021-08-11 | 2021-11-05 | 浙江理工大学 | 一种防感染复合层医用敷料的制备方法及其用途 |
| CN114870095A (zh) * | 2022-05-06 | 2022-08-09 | 南通大学 | 一种表面具有各向异性纳米拓扑结构的组织工程移植物构建方法 |
| CN115198446A (zh) * | 2022-08-22 | 2022-10-18 | 青岛农业大学 | 一种静电纺丝纤维保鲜膜、其制备方法及应用 |
| CN116271220A (zh) * | 2023-02-21 | 2023-06-23 | 东南大学 | 一种快速诱导干细胞增殖和分化的组织工程支架的制备方法及其应用 |
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| JP2008502739A (ja) | 2004-06-11 | 2008-01-31 | トラスティーズ オブ タフツ カレッジ | 絹に基づく薬物送達システム |
| WO2006033196A1 (ja) * | 2004-09-22 | 2006-03-30 | Shinano Kenshi Kabushiki Kaisha | 創傷被覆材 |
| WO2006076711A2 (en) | 2005-01-14 | 2006-07-20 | Trustees Of Tufts College | Fibrous protein fusions and use thereof in the formation of advanced organic/inorganic composite materials |
| US9290579B2 (en) | 2005-04-20 | 2016-03-22 | Trustees Of Tufts College | Covalently immobilized protein gradients in three-dimensional porous scaffolds |
| US8354501B2 (en) | 2005-08-02 | 2013-01-15 | Trustees Of Tufts College | Methods for stepwise deposition of silk fibroin coatings |
| JP5249785B2 (ja) * | 2006-01-27 | 2013-07-31 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 生体模倣足場材 |
| WO2008118133A2 (en) | 2006-09-26 | 2008-10-02 | Trustees Of Tufts College | Silk microspheres for encapsulation and controlled release |
| WO2008118211A2 (en) | 2006-11-03 | 2008-10-02 | Trustees Of Tufts College | Biopolymer photonic crystals and method of manufacturing the same |
| WO2008127405A2 (en) | 2006-11-03 | 2008-10-23 | Trustees Of Tufts College | Microfluidic device with a cylindrical microchannel and a method for fabricating same |
| EP2086749B1 (en) | 2006-11-03 | 2013-05-08 | Trustees Of Tufts College | Nanopatterned biopolymer optical device and method of manufacturing the same |
| CA2704768A1 (en) | 2006-11-03 | 2008-10-23 | Trustees Of Tufts College | Biopolymer sensor and method of manufacturing the same |
| WO2008127403A2 (en) | 2006-11-03 | 2008-10-23 | Trustees Of Tufts College | Biopolymer optofluidic device and method of manufacturing the same |
| WO2008106485A2 (en) | 2007-02-27 | 2008-09-04 | Trustees Of Tufts College | Tissue-engineered silk organs |
| CN101772348B (zh) | 2007-05-29 | 2014-07-16 | 塔夫茨大学信托人 | 利用超声处理使丝纤蛋白凝胶化的方法 |
| US9808557B2 (en) | 2007-08-10 | 2017-11-07 | Trustees Of Tufts College | Tubular silk compositions and methods of use thereof |
| CA2742844C (en) | 2007-11-05 | 2017-02-28 | Trustees Of Tufts College | Fabrication of silk fibroin photonic structures by nanocontact imprinting |
| EP2249886A4 (en) | 2008-02-07 | 2013-05-22 | Tufts College | 3-DIMENSIONAL SILK HYDROXYLAPATITE COMPOSITIONS |
| US8206774B2 (en) | 2008-03-13 | 2012-06-26 | Trustees Of Tufts College | Diazonium salt modification of silk polymer |
| WO2009126689A2 (en) | 2008-04-08 | 2009-10-15 | Trustees Of Tufts College | System and method for making biomaterial structures |
| US9040073B2 (en) | 2008-05-15 | 2015-05-26 | Trustees Of Tufts College | Silk polymer-based adenosine release: therapeutic potential for epilepsy |
| JP2011525254A (ja) | 2008-06-18 | 2011-09-15 | トラスティーズ オブ タフツ カレッジ | 食用のホログラフィック絹製品 |
| US8501172B2 (en) | 2008-09-26 | 2013-08-06 | Trustees Of Tufts College | pH-induced silk gels and uses thereof |
| CA2805403A1 (en) | 2009-07-10 | 2011-01-13 | Trustees Of Tufts College | Bioengineered silk protein-based nucleic acid delivery systems |
-
2010
- 2010-07-14 IN IN445DEN2012 patent/IN2012DN00445A/en unknown
- 2010-07-14 CA CA2812635A patent/CA2812635A1/en not_active Abandoned
- 2010-07-14 JP JP2012520744A patent/JP2012533354A/ja active Pending
- 2010-07-14 US US13/382,967 patent/US8728498B2/en active Active
- 2010-07-14 EP EP10800470.6A patent/EP2453931A4/en not_active Withdrawn
- 2010-07-14 WO PCT/US2010/041953 patent/WO2011008842A2/en not_active Ceased
-
2012
- 2012-01-10 IL IL217464A patent/IL217464A0/en unknown
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