JP2012532874A5 - - Google Patents

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JP2012532874A5
JP2012532874A5 JP2012519660A JP2012519660A JP2012532874A5 JP 2012532874 A5 JP2012532874 A5 JP 2012532874A5 JP 2012519660 A JP2012519660 A JP 2012519660A JP 2012519660 A JP2012519660 A JP 2012519660A JP 2012532874 A5 JP2012532874 A5 JP 2012532874A5
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pharmaceutically acceptable
pharmaceutical formulation
acceptable salt
compound according
fluoropicolinamide
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JP2012519660A
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JP2012532874A (ja
JP5666578B2 (ja
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Priority claimed from PCT/US2010/041034 external-priority patent/WO2011005738A1/en
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JP2012519660A 2009-07-09 2010-07-06 Bace阻害剤 Expired - Fee Related JP5666578B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US22424109P 2009-07-09 2009-07-09
US61/224,241 2009-07-09
PCT/US2010/041034 WO2011005738A1 (en) 2009-07-09 2010-07-06 Bace inhibitors

Publications (3)

Publication Number Publication Date
JP2012532874A JP2012532874A (ja) 2012-12-20
JP2012532874A5 true JP2012532874A5 (US07714131-20100511-C00001.png) 2013-08-15
JP5666578B2 JP5666578B2 (ja) 2015-02-12

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JP2012519660A Expired - Fee Related JP5666578B2 (ja) 2009-07-09 2010-07-06 Bace阻害剤

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US (2) US8278441B2 (US07714131-20100511-C00001.png)
EP (1) EP2451793B1 (US07714131-20100511-C00001.png)
JP (1) JP5666578B2 (US07714131-20100511-C00001.png)
KR (1) KR101362557B1 (US07714131-20100511-C00001.png)
CN (1) CN102471296B (US07714131-20100511-C00001.png)
AR (1) AR077277A1 (US07714131-20100511-C00001.png)
AU (1) AU2010270691B8 (US07714131-20100511-C00001.png)
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CA (1) CA2764429C (US07714131-20100511-C00001.png)
CL (1) CL2012000033A1 (US07714131-20100511-C00001.png)
CO (1) CO6480979A2 (US07714131-20100511-C00001.png)
CR (1) CR20120011A (US07714131-20100511-C00001.png)
DO (1) DOP2012000004A (US07714131-20100511-C00001.png)
EA (1) EA019892B1 (US07714131-20100511-C00001.png)
EC (1) ECSP12011581A (US07714131-20100511-C00001.png)
HN (1) HN2012000012A (US07714131-20100511-C00001.png)
IL (1) IL216742A0 (US07714131-20100511-C00001.png)
MA (1) MA33492B1 (US07714131-20100511-C00001.png)
MX (1) MX2012000510A (US07714131-20100511-C00001.png)
NZ (1) NZ596579A (US07714131-20100511-C00001.png)
PE (1) PE20120632A1 (US07714131-20100511-C00001.png)
SG (1) SG177594A1 (US07714131-20100511-C00001.png)
TN (1) TN2011000673A1 (US07714131-20100511-C00001.png)
TW (1) TWI405765B (US07714131-20100511-C00001.png)
WO (1) WO2011005738A1 (US07714131-20100511-C00001.png)
ZA (1) ZA201109385B (US07714131-20100511-C00001.png)

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TW201718543A (zh) 2015-08-12 2017-06-01 H 朗德貝克公司 作爲bace1抑制劑之2-胺基-3-氟-3-(氟甲基)-6-甲基-6-苯基-3,4,5,6-四氫吡啶
JP2018527338A (ja) * 2015-08-12 2018-09-20 ハー・ルンドベック・アクチエゼルスカベット BACE1阻害剤としての2−アミノ−7a−フェニル−3,4,4a,5,7,7a−ヘキサヒドロフロ[3,4−b]ピリジン
JP2018531923A (ja) 2015-09-24 2018-11-01 ファイザー・インク N−[2−(2−アミノ−6,6−二置換−4,4a,5,6−テトラヒドロピラノ[3,4−d][1,3]チアジン−8a(8H)−イル)−1,3−チアゾール−4−イル]アミド
JP2018534251A (ja) 2015-09-24 2018-11-22 ファイザー・インク Bace阻害剤として有用なn−[2−(3−アミノ−2,5−ジメチル−1,1−ジオキシド−5,6−ジヒドロ−2h−1,2,4−チアジアジン−5−イル)−1,3−チアゾール−4−イル]アミド
JP2018531924A (ja) 2015-09-24 2018-11-01 ファイザー・インク テトラヒドロピラノ[3,4−d][1,3]オキサジン誘導体、およびbace阻害剤としてのその使用
TWI675034B (zh) * 2016-05-20 2019-10-21 美商美國禮來大藥廠 四氫呋喃并<img align="absmiddle" height="18px" width="27px" file="d10999.TIF" alt="其他非圖式 ed10999.png" img-content="tif" orientation="portrait" inline="yes" giffile="ed10999.png"></img>化合物及其作為選擇性BACE1抑制劑之用途
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MX2019007104A (es) 2016-12-15 2019-11-05 Amgen Inc Derivados de dioxido de 1,4-tiazina y dioxido de 1,2,4-tiadiazina como inhibidores de beta-secretasa y metodos de uso.
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