JP2012531581A5 - - Google Patents
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- JP2012531581A5 JP2012531581A5 JP2012516974A JP2012516974A JP2012531581A5 JP 2012531581 A5 JP2012531581 A5 JP 2012531581A5 JP 2012516974 A JP2012516974 A JP 2012516974A JP 2012516974 A JP2012516974 A JP 2012516974A JP 2012531581 A5 JP2012531581 A5 JP 2012531581A5
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- JP
- Japan
- Prior art keywords
- antigens
- antigen
- seq
- auc
- subset
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
- 239000000427 antigen Substances 0.000 description 76
- 102000036639 antigens Human genes 0.000 description 75
- 108091007433 antigens Proteins 0.000 description 75
- 239000012895 dilution Substances 0.000 description 28
- 238000010790 dilution Methods 0.000 description 28
- 206010028980 Neoplasm Diseases 0.000 description 16
- 238000004458 analytical method Methods 0.000 description 16
- 239000000523 sample Substances 0.000 description 16
- 238000005259 measurement Methods 0.000 description 14
- 206010033128 Ovarian cancer Diseases 0.000 description 13
- 206010061535 Ovarian neoplasm Diseases 0.000 description 13
- 238000012360 testing method Methods 0.000 description 13
- 206010006187 Breast cancer Diseases 0.000 description 10
- 208000026310 Breast neoplasm Diseases 0.000 description 10
- 201000011510 cancer Diseases 0.000 description 10
- 238000007689 inspection Methods 0.000 description 9
- 238000003745 diagnosis Methods 0.000 description 7
- 238000009499 grossing Methods 0.000 description 7
- 238000000034 method Methods 0.000 description 6
- 239000012472 biological sample Substances 0.000 description 5
- 238000004364 calculation method Methods 0.000 description 5
- 238000001514 detection method Methods 0.000 description 5
- 102000004196 processed proteins & peptides Human genes 0.000 description 4
- 108090000765 processed proteins & peptides Proteins 0.000 description 4
- 238000002965 ELISA Methods 0.000 description 3
- 238000007477 logistic regression Methods 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 102000004169 proteins and genes Human genes 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- UQLDLKMNUJERMK-UHFFFAOYSA-L di(octadecanoyloxy)lead Chemical compound [Pb+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O UQLDLKMNUJERMK-UHFFFAOYSA-L 0.000 description 2
- 238000013154 diagnostic monitoring Methods 0.000 description 2
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- 230000028993 immune response Effects 0.000 description 2
- 238000012417 linear regression Methods 0.000 description 2
- 239000012898 sample dilution Substances 0.000 description 2
- 238000000926 separation method Methods 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- 241000283707 Capra Species 0.000 description 1
- 206010009944 Colon cancer Diseases 0.000 description 1
- 206010058467 Lung neoplasm malignant Diseases 0.000 description 1
- 206010060862 Prostate cancer Diseases 0.000 description 1
- 208000000236 Prostatic Neoplasms Diseases 0.000 description 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 230000003796 beauty Effects 0.000 description 1
- 238000001574 biopsy Methods 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 210000000481 breast Anatomy 0.000 description 1
- 210000000170 cell membrane Anatomy 0.000 description 1
- 208000029742 colonic neoplasm Diseases 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000012774 diagnostic algorithm Methods 0.000 description 1
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- 238000011156 evaluation Methods 0.000 description 1
- 230000007717 exclusion Effects 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 230000016784 immunoglobulin production Effects 0.000 description 1
- 201000005202 lung cancer Diseases 0.000 description 1
- 208000020816 lung neoplasm Diseases 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 239000013610 patient sample Substances 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 241000894007 species Species 0.000 description 1
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- 238000007619 statistical method Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000013598 vector Substances 0.000 description 1
Images
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21953909P | 2009-06-23 | 2009-06-23 | |
| US61/219,539 | 2009-06-23 | ||
| PCT/IL2010/000498 WO2010150254A2 (en) | 2009-06-23 | 2010-06-23 | A method and system for the detection of cancer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012531581A JP2012531581A (ja) | 2012-12-10 |
| JP2012531581A5 true JP2012531581A5 (enExample) | 2013-08-08 |
Family
ID=42710569
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012516974A Pending JP2012531581A (ja) | 2009-06-23 | 2010-06-23 | 癌の検出のための方法およびシステム |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20120202226A1 (enExample) |
| EP (1) | EP2446272A2 (enExample) |
| JP (1) | JP2012531581A (enExample) |
| KR (1) | KR20120098992A (enExample) |
| AU (1) | AU2010264067A1 (enExample) |
| SG (1) | SG176962A1 (enExample) |
| WO (1) | WO2010150254A2 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USRE50076E1 (en) | 2015-12-30 | 2024-08-13 | Hyundai Heavy Industries Co., Ltd. | Liquefied gas carrier |
| US11544582B2 (en) * | 2016-02-02 | 2023-01-03 | Ambertag, Inc. | Predictive modelling to score customer leads using data analytics using an end-to-end automated, sampled approach with iterative local and global optimization |
| CN108780092A (zh) | 2016-03-07 | 2018-11-09 | 豪夫迈·罗氏有限公司 | 抗p53抗体的检测 |
| JP7128196B2 (ja) | 2017-03-01 | 2022-08-30 | エフ．ホフマン－ラ ロシュ アーゲー | 検体の存在に関する生体サンプルの分類のためのシステムおよび方法 |
| KR102007664B1 (ko) * | 2017-07-17 | 2019-08-07 | 김준 | 암 진단기 및 이를 이용한 암 진단시스템 |
| US11804298B2 (en) | 2017-07-17 | 2023-10-31 | Joon Kim | Cancer diagnostic apparatus and cancer diagnostic system using the same |
| ES2876038T3 (es) | 2018-02-18 | 2021-11-11 | Marquez Marquez Lidia | Método, aparato y kit para la detección temprana de cáncer de mama |
| JP7157941B2 (ja) * | 2020-08-05 | 2022-10-21 | 憲一 佐藤 | 癌罹患判定方法、装置、およびプログラム |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9810040D0 (en) * | 1998-05-11 | 1998-07-08 | Univ Nottingham | Blood borne tumour markers |
| WO2000061636A2 (en) * | 1999-04-14 | 2000-10-19 | Research Corporation Technologies, Inc. | Aberrantly glycosylated antibodies as marker for cancer |
| AU2002257647A1 (en) * | 2001-03-09 | 2002-09-24 | Callistogen Ag | Induction of anti-tumor cytotoxic t-lymphocytes in humans using peptide epitopes found by computer based algorithms for vaccination |
| EP1367395A1 (de) * | 2002-05-02 | 2003-12-03 | B.R.A.H.M.S Aktiengesellschaft | Diagnose von Neoplasmen mit Hilfe von anti-Gangliosid-Antikörpern |
| GB2426581A (en) * | 2005-05-27 | 2006-11-29 | Univ Nottingham | Immunoassay methods |
| MX2008016352A (es) | 2006-07-08 | 2009-04-17 | Univ Kentucky Res Found | Analisis diagnostico para cancer de pulmon. |
| CN101632020B (zh) * | 2006-09-13 | 2013-11-27 | 昂西免疫有限公司 | 改进的免疫测定方法 |
| AU2007297310B2 (en) | 2006-09-13 | 2013-11-07 | Oncimmune Limited | Improved immunoassay methods |
| WO2009074276A2 (en) * | 2007-12-10 | 2009-06-18 | Roche Diagnostics Gmbh | Marker panel for colorectal cancer |
-
2010
- 2010-06-23 AU AU2010264067A patent/AU2010264067A1/en not_active Abandoned
- 2010-06-23 EP EP10735340A patent/EP2446272A2/en not_active Withdrawn
- 2010-06-23 WO PCT/IL2010/000498 patent/WO2010150254A2/en not_active Ceased
- 2010-06-23 US US13/380,408 patent/US20120202226A1/en not_active Abandoned
- 2010-06-23 KR KR1020127001838A patent/KR20120098992A/ko not_active Withdrawn
- 2010-06-23 JP JP2012516974A patent/JP2012531581A/ja active Pending
- 2010-06-23 SG SG2011095403A patent/SG176962A1/en unknown
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