JP2012530086A5 - - Google Patents
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- Publication number
- JP2012530086A5 JP2012530086A5 JP2012515356A JP2012515356A JP2012530086A5 JP 2012530086 A5 JP2012530086 A5 JP 2012530086A5 JP 2012515356 A JP2012515356 A JP 2012515356A JP 2012515356 A JP2012515356 A JP 2012515356A JP 2012530086 A5 JP2012530086 A5 JP 2012530086A5
- Authority
- JP
- Japan
- Prior art keywords
- disorder
- dementia
- disease
- group
- neurodegenerative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/DK2009/050134 WO2009152825A1 (en) | 2008-06-20 | 2009-06-19 | Novel phenylimidazole derivatives as pde10a enzyme inhibitors |
| DKPCT/DK2009/050134 | 2009-06-19 | ||
| PCT/DK2010/050147 WO2010145668A1 (en) | 2009-06-19 | 2010-06-17 | Novel phenylimidazole derivative as pde10a enzyme inhibitor |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012530086A JP2012530086A (ja) | 2012-11-29 |
| JP2012530086A5 true JP2012530086A5 (enExample) | 2015-01-29 |
| JP5768044B2 JP5768044B2 (ja) | 2015-08-26 |
Family
ID=42321053
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012515356A Expired - Fee Related JP5768044B2 (ja) | 2009-06-19 | 2010-06-17 | Ｐｄｅ１０ａ酵素阻害剤としての新規のフェニルイミダゾール誘導体 |
Country Status (28)
| Country | Link |
|---|---|
| EP (1) | EP2443105B1 (enExample) |
| JP (1) | JP5768044B2 (enExample) |
| AR (1) | AR077144A1 (enExample) |
| AU (1) | AU2010262190B2 (enExample) |
| BR (1) | BRPI1015983A2 (enExample) |
| CA (1) | CA2765750A1 (enExample) |
| CR (1) | CR20110654A (enExample) |
| CY (1) | CY1115971T1 (enExample) |
| DK (1) | DK2443105T3 (enExample) |
| DO (1) | DOP2011000397A (enExample) |
| ES (1) | ES2527216T3 (enExample) |
| GE (1) | GEP20146100B (enExample) |
| GT (1) | GT201100322A (enExample) |
| HR (1) | HRP20141222T1 (enExample) |
| IL (1) | IL216684A (enExample) |
| MA (1) | MA33367B1 (enExample) |
| MX (1) | MX2011013400A (enExample) |
| MY (1) | MY156785A (enExample) |
| NZ (1) | NZ597203A (enExample) |
| PL (1) | PL2443105T3 (enExample) |
| PT (1) | PT2443105E (enExample) |
| SG (1) | SG176680A1 (enExample) |
| SI (1) | SI2443105T1 (enExample) |
| SM (1) | SMT201500003B (enExample) |
| TW (1) | TW201100430A (enExample) |
| UA (1) | UA106378C2 (enExample) |
| WO (1) | WO2010145668A1 (enExample) |
| ZA (1) | ZA201109271B (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI501965B (zh) | 2008-06-20 | 2015-10-01 | Lundbeck & Co As H | 作為ｐｄｅ１０ａ酵素抑制劑之新穎苯基咪唑衍生物 |
| US8133897B2 (en) | 2008-06-20 | 2012-03-13 | H. Lundbeck A/S | Phenylimidazole derivatives as PDE10A enzyme inhibitors |
| TWI485151B (zh) | 2009-12-17 | 2015-05-21 | Lundbeck & Co As H | 作為ｐｄｅ１０ａ酵素抑制劑之雜芳香族苯基咪唑衍生物 |
| US8552045B2 (en) | 2010-11-19 | 2013-10-08 | H. Lundbeck A/S | Tricyclic imidazole compounds as PDE10 inhibitors |
| JO3089B1 (ar) * | 2010-11-19 | 2017-03-15 | H Lundbeck As | مشتقات ايميدازول كمثبطات لانزيمات pde10a |
| WO2012112946A1 (en) | 2011-02-18 | 2012-08-23 | Allergan, Inc. | Substituted 6,7-dialkoxy-3-isoquinolinol derivatives as inhibitors of phosphodiesterase 10 (pde10a) |
| WO2013034758A1 (en) * | 2011-09-09 | 2013-03-14 | H. Lundbeck A/S | Substituted triazolopyrazines and uses thereof |
| US9056863B2 (en) | 2011-09-09 | 2015-06-16 | H. Lundbeck A/S | Substituted 2,3,5,9,9B-pentaazacyclopenta[a]naphthalenes and uses thereof |
| CN103874701A (zh) * | 2011-09-09 | 2014-06-18 | H.隆德贝克有限公司 | 吡啶化合物和其用途 |
| WO2013034755A1 (en) * | 2011-09-09 | 2013-03-14 | H. Lundbeck A/S | Triazolopyrazine derivatives and their use for treating neurological and psychiatric disorders |
| TWI570124B (zh) | 2011-12-21 | 2017-02-11 | Ｈ 朗德貝克公司 | 作為ｐｄｅ１０ａ酵素抑制劑的喹啉衍生物 |
| WO2013107856A1 (en) * | 2012-01-20 | 2013-07-25 | H. Lundbeck A/S | Imidazole derivatives as pde10a enzyme inhibitors |
| WO2013127817A1 (en) | 2012-02-27 | 2013-09-06 | H. Lundbeck A/S | Imidazole derivatives as pde10a enzyme inhibitors |
| WO2014071044A1 (en) | 2012-11-01 | 2014-05-08 | Allergan, Inc. | Substituted 6,7-dialkoxy-3-isoquinoline derivatives as inhibitors of phosphodiesterase 10 (pde10a) |
| US9200016B2 (en) | 2013-12-05 | 2015-12-01 | Allergan, Inc. | Substituted 6, 7-dialkoxy-3-isoquinoline derivatives as inhibitors of phosphodiesterase 10 (PDE 10A) |
| BR112020013743A2 (pt) * | 2018-11-06 | 2020-12-01 | H. Lundbeck A/S | hemiadipato de 5,8-dimetil-2-[2-(1-metil-4-fenil-1h-imidazol-2-il)-etil]-[1,2,4]triazolo[1,5-a]pirazina |
| WO2020094592A1 (en) * | 2018-11-06 | 2020-05-14 | H. Lundbeck A/S | Compounds for treating negative symptoms and cognitive impairments |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4826833A (en) | 1984-01-30 | 1989-05-02 | Pfizer Inc. | 6-(Substituted)methylene-penicillanic and 6-(substituted)hydroxymethylpenicillanic acids and derivatives thereof |
| US20030032579A1 (en) | 2001-04-20 | 2003-02-13 | Pfizer Inc. | Therapeutic use of selective PDE10 inhibitors |
| IL149106A0 (en) | 2001-04-20 | 2002-11-10 | Pfizer Prod Inc | Therapeutic use of selective pde10 inhibitors |
| FR2824065A1 (fr) | 2001-04-26 | 2002-10-31 | Neuro3D | Composes inhibiteurs des phosphodiesterases des nucleotides cycliques, preparation et utilisations |
| WO2004024705A1 (ja) | 2002-09-10 | 2004-03-25 | Takeda Pharmaceutical Company Limited | ５員複素環化合物 |
| AU2003288352A1 (en) | 2002-10-30 | 2004-06-07 | Centre National De La Recherche Scientifique (Cnrs) | Cyclic nucleotide phosphodiesterase inhibitors, preparation and uses |
| EP1641457B1 (en) | 2003-06-30 | 2009-08-05 | Nycomed GmbH | Pyrrolo-dihydroisoquinoline derivatives as pde10 inhibitors |
| MXPA05013553A (es) | 2003-06-30 | 2006-03-09 | Altana Pharma Ag | Pirrolodihidroisoquinolinas como inhibidores de pde10. |
| EP1651251A4 (en) | 2003-07-31 | 2008-06-18 | Bayer Pharmaceuticals Corp | METHOD FOR THE TREATMENT OF DIABETES AND RELATED DISEASES USING PDE 10A INHIBITORS |
| EP1723134A2 (en) | 2004-02-18 | 2006-11-22 | Pfizer Products Incorporated | Tetrahydroisoquinolinyl derivatives of quinazoline and isoquinoline |
| FR2870539B1 (fr) | 2004-05-19 | 2006-08-04 | Greenpharma Sa Sa | Nouvelles methodes et medicaments |
| BRPI0511854A (pt) | 2004-06-07 | 2008-01-15 | Pfizer Prod Inc | inibição de fosfodiestearase 10 como tratamento para condições relacionados com a obesidade e relacionadas a sìndrome metabólica |
| US20060019975A1 (en) | 2004-07-23 | 2006-01-26 | Pfizer Inc | Novel piperidyl derivatives of quinazoline and isoquinoline |
| CA2578996A1 (en) | 2004-09-03 | 2006-03-16 | Memory Pharmaceuticals Corporation | 4-substituted 4, 6-dialkoxy-cinnoline derivatives as phospodiesterase 10 inhibitors for the treatment of psychiatric or neurological syndroms |
| US20060183763A1 (en) * | 2004-12-31 | 2006-08-17 | Pfizer Inc | Novel pyrrolidyl derivatives of heteroaromatic compounds |
| MX2008010668A (es) * | 2006-02-21 | 2008-10-01 | Amgen Inc | Derivados de cinolina como inhibidores de fosfodiesterasa 10. |
| TWI501965B (zh) | 2008-06-20 | 2015-10-01 | Lundbeck & Co As H | 作為ｐｄｅ１０ａ酵素抑制劑之新穎苯基咪唑衍生物 |
-
2010
- 2010-06-17 PT PT107253734T patent/PT2443105E/pt unknown
- 2010-06-17 GE GEAP201012536A patent/GEP20146100B/en unknown
- 2010-06-17 NZ NZ597203A patent/NZ597203A/xx not_active IP Right Cessation
- 2010-06-17 SI SI201030841T patent/SI2443105T1/sl unknown
- 2010-06-17 HR HRP20141222AT patent/HRP20141222T1/hr unknown
- 2010-06-17 BR BRPI1015983A patent/BRPI1015983A2/pt not_active Application Discontinuation
- 2010-06-17 PL PL10725373T patent/PL2443105T3/pl unknown
- 2010-06-17 DK DK10725373.4T patent/DK2443105T3/en active
- 2010-06-17 JP JP2012515356A patent/JP5768044B2/ja not_active Expired - Fee Related
- 2010-06-17 MY MYPI2011005865A patent/MY156785A/en unknown
- 2010-06-17 UA UAA201200499A patent/UA106378C2/ru unknown
- 2010-06-17 SG SG2011089919A patent/SG176680A1/en unknown
- 2010-06-17 MA MA34464A patent/MA33367B1/fr unknown
- 2010-06-17 AU AU2010262190A patent/AU2010262190B2/en not_active Ceased
- 2010-06-17 WO PCT/DK2010/050147 patent/WO2010145668A1/en not_active Ceased
- 2010-06-17 MX MX2011013400A patent/MX2011013400A/es unknown
- 2010-06-17 EP EP10725373.4A patent/EP2443105B1/en active Active
- 2010-06-17 CA CA2765750A patent/CA2765750A1/en not_active Abandoned
- 2010-06-17 ES ES10725373.4T patent/ES2527216T3/es active Active
- 2010-06-18 TW TW099119840A patent/TW201100430A/zh unknown
- 2010-06-18 AR ARP100102165A patent/AR077144A1/es active IP Right Grant
-
2011
- 2011-11-29 IL IL216684A patent/IL216684A/en active IP Right Grant
- 2011-12-08 CR CR20110654A patent/CR20110654A/es unknown
- 2011-12-14 GT GT201100322A patent/GT201100322A/es unknown
- 2011-12-15 ZA ZA2011/09271A patent/ZA201109271B/en unknown
- 2011-12-19 DO DO2011000397A patent/DOP2011000397A/es unknown
-
2014
- 2014-12-19 CY CY20141101071T patent/CY1115971T1/el unknown
-
2015
- 2015-01-05 SM SM201500003T patent/SMT201500003B/xx unknown
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