JP2012526850A - サイクリン依存性キナーゼ阻害剤及びその用法 - Google Patents

サイクリン依存性キナーゼ阻害剤及びその用法 Download PDF

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JP2012526850A
JP2012526850A JP2012511031A JP2012511031A JP2012526850A JP 2012526850 A JP2012526850 A JP 2012526850A JP 2012511031 A JP2012511031 A JP 2012511031A JP 2012511031 A JP2012511031 A JP 2012511031A JP 2012526850 A JP2012526850 A JP 2012526850A
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cdk4
patient
cells
cyclin
dependent kinase
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JP2012526850A5 (enExample
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イー シャープレス ノーマン
ジェイ ロバーツ パトリック
ウォン クウォ−キン
リュー ヤン
ジョンソン ソレン
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University of North Carolina at Chapel Hill
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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JP2012511031A 2009-05-13 2010-05-13 サイクリン依存性キナーゼ阻害剤及びその用法 Pending JP2012526850A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17772409P 2009-05-13 2009-05-13
US61/177,724 2009-05-13
PCT/US2010/034816 WO2010132725A2 (en) 2009-05-13 2010-05-13 Cyclin dependent kinase inhibitors and methods of use

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JP2012526850A true JP2012526850A (ja) 2012-11-01
JP2012526850A5 JP2012526850A5 (enExample) 2013-06-27

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US (2) US20120100100A1 (enExample)
EP (4) EP3025724B1 (enExample)
JP (1) JP2012526850A (enExample)
CN (1) CN102458443A (enExample)
AU (1) AU2010248886A1 (enExample)
CA (1) CA2761896A1 (enExample)
ES (1) ES2561216T3 (enExample)
IL (1) IL216315A0 (enExample)
WO (1) WO2010132725A2 (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
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JP2016513737A (ja) * 2013-03-15 2016-05-16 ジー１、セラピューティクス、インコーポレイテッドＧ１ Ｔｈｅｒａｐｅｕｔｉｃｓ， Ｉｎｃ． 化学療法の間の正常細胞の一時的な保護
JP2017524702A (ja) * 2014-07-26 2017-08-31 サンシャイン・レイク・ファーマ・カンパニー・リミテッドＳｕｎｓｈｉｎｅ Ｌａｋｅ Ｐｈａｒｍａ Ｃｏ．，Ｌｔｄ． ＣＤＫ阻害剤としての２−アミノ−ピリド［２，３−ｄ］ピリミジン−７（８Ｈ）−オン誘導体及びその使用
JP2021523202A (ja) * 2018-05-14 2021-09-02 ファイザー・インク 経口溶液製剤

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EP3025724B1 (en) 2009-05-13 2018-07-11 The University of North Carolina At Chapel Hill Cyclin dependent kinase inhibitors and methods of use
US8691830B2 (en) 2010-10-25 2014-04-08 G1 Therapeutics, Inc. CDK inhibitors
KR102186969B1 (ko) 2010-10-25 2020-12-04 쥐원 쎄라퓨틱스, 인크. Cdk 억제제
WO2012068381A2 (en) 2010-11-17 2012-05-24 The University Of North Carolina At Chapel Hill Protection of renal tissues from schema through inhibition of the proliferative kisses cdk4 and cdk6
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KR102962306B1 (ko) 2018-08-24 2026-05-08 쥐원 쎄라퓨틱스, 인크. 1,4-디아자스피로[5.5]운데칸-3-온의 개선된 합성
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CN117643591A (zh) * 2023-02-23 2024-03-05 四川大学华西医院 一种用于mycn扩增型rb的抑制剂及抑制效果验证方法
WO2025085360A1 (en) 2023-10-16 2025-04-24 The Board Of Regents Of The University Of Oklahoma Heteroarotinoids and/or cdk4/6 inhibitors for treating human papillomavirus (hpv)-induced dysplasias, warts, and cancer in hpv-infected subjects

Citations (4)

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