JP2012525358A5 - - Google Patents
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- Publication number
- JP2012525358A5 JP2012525358A5 JP2012507765A JP2012507765A JP2012525358A5 JP 2012525358 A5 JP2012525358 A5 JP 2012525358A5 JP 2012507765 A JP2012507765 A JP 2012507765A JP 2012507765 A JP2012507765 A JP 2012507765A JP 2012525358 A5 JP2012525358 A5 JP 2012525358A5
- Authority
- JP
- Japan
- Prior art keywords
- treatment
- medicament
- allopurinol
- induced
- hfsr
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003814 drug Substances 0.000 claims description 13
- OFCNXPDARWKPPY-UHFFFAOYSA-N allopurinol Chemical compound OC1=NC=NC2=C1C=NN2 OFCNXPDARWKPPY-UHFFFAOYSA-N 0.000 claims description 11
- 229960003459 allopurinol Drugs 0.000 claims description 11
- 239000002147 L01XE04 - Sunitinib Substances 0.000 claims description 5
- 229960001796 sunitinib Drugs 0.000 claims description 5
- WINHZLLDWRZWRT-ATVHPVEESA-N sunitinib Chemical compound CCN(CC)CCNC(=O)C1=C(C)NC(\C=C/2C3=CC(F)=CC=C3NC\2=O)=C1C WINHZLLDWRZWRT-ATVHPVEESA-N 0.000 claims description 5
- MLDQJTXFUGDVEO-UHFFFAOYSA-N BAY-43-9006 Chemical compound C1=NC(C(=O)NC)=CC(OC=2C=CC(NC(=O)NC=3C=C(C(Cl)=CC=3)C(F)(F)F)=CC=2)=C1 MLDQJTXFUGDVEO-UHFFFAOYSA-N 0.000 claims description 4
- 239000005511 L01XE05 - Sorafenib Substances 0.000 claims description 4
- 229960003787 sorafenib Drugs 0.000 claims description 4
- 239000006071 cream Substances 0.000 claims description 3
- 206010040914 Skin reaction Diseases 0.000 claims 7
- 230000035483 skin reaction Effects 0.000 claims 7
- 231100000430 skin reaction Toxicity 0.000 claims 7
- 230000002265 prevention Effects 0.000 claims 4
- 150000003839 salts Chemical class 0.000 claims 4
- 229940043355 kinase inhibitor Drugs 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 239000003757 phosphotransferase inhibitor Substances 0.000 claims 2
- 238000011200 topical administration Methods 0.000 claims 2
- 108091000080 Phosphotransferase Proteins 0.000 claims 1
- 239000008309 hydrophilic cream Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 102000020233 phosphotransferase Human genes 0.000 claims 1
- 208000024891 symptom Diseases 0.000 description 2
- 230000000699 topical effect Effects 0.000 description 2
- 102000011782 Keratins Human genes 0.000 description 1
- 108010076876 Keratins Proteins 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 206010061309 Neoplasm progression Diseases 0.000 description 1
- 206010067482 No adverse event Diseases 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000003780 keratinization Effects 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000005751 tumor progression Effects 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21489409P | 2009-04-29 | 2009-04-29 | |
| US61/214,894 | 2009-04-29 | ||
| EP09382058A EP2246057A1 (en) | 2009-04-29 | 2009-04-29 | Use of allopurinol for the treatment of hand foot skin reaction |
| EP09382058.7 | 2009-04-29 | ||
| PCT/EP2010/055806 WO2010125143A1 (en) | 2009-04-29 | 2010-04-29 | Use of allopurinol for the treatment of hand foot skin reaction |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012525358A JP2012525358A (ja) | 2012-10-22 |
| JP2012525358A5 true JP2012525358A5 (cg-RX-API-DMAC7.html) | 2014-12-11 |
| JP6007101B2 JP6007101B2 (ja) | 2016-10-12 |
Family
ID=40897536
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012507765A Expired - Fee Related JP6007101B2 (ja) | 2009-04-29 | 2010-04-29 | 手足皮膚反応治療のためのアロプリノールの使用 |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US8623878B2 (cg-RX-API-DMAC7.html) |
| EP (2) | EP2246057A1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6007101B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR20120049848A (cg-RX-API-DMAC7.html) |
| CN (1) | CN102421436B (cg-RX-API-DMAC7.html) |
| AR (1) | AR076505A1 (cg-RX-API-DMAC7.html) |
| AU (2) | AU2010243594A1 (cg-RX-API-DMAC7.html) |
| BR (1) | BRPI1011971A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2759085C (cg-RX-API-DMAC7.html) |
| DK (1) | DK2424538T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2434366T3 (cg-RX-API-DMAC7.html) |
| HR (1) | HRP20131070T1 (cg-RX-API-DMAC7.html) |
| IL (1) | IL215831A (cg-RX-API-DMAC7.html) |
| ME (1) | ME01567B (cg-RX-API-DMAC7.html) |
| MX (1) | MX2011011529A (cg-RX-API-DMAC7.html) |
| NZ (1) | NZ595901A (cg-RX-API-DMAC7.html) |
| PL (1) | PL2424538T3 (cg-RX-API-DMAC7.html) |
| PT (1) | PT2424538E (cg-RX-API-DMAC7.html) |
| RS (1) | RS53005B (cg-RX-API-DMAC7.html) |
| RU (1) | RU2543325C2 (cg-RX-API-DMAC7.html) |
| SI (1) | SI2424538T1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2010125143A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9220713B2 (en) | 2009-10-16 | 2015-12-29 | Duke University | Compositions and methods for the treatment of drug-induced hand-foot syndrome |
| JP2014502998A (ja) * | 2011-01-18 | 2014-02-06 | ビカス セラピューティクス，エルエルシー | 薬学的組成物ならびに薬学的組成物を作製および使用するための方法 |
| JP2021506958A (ja) | 2017-12-13 | 2021-02-22 | オンクォリティ ファーマシューティカルズ チャイナ エルティーディーＯｎｑｕａｌｉｔｙ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｃｈｉｎａ Ｌｔｄ． | Ｅｇｆｒ阻害に関連する疾患を予防又は治療する方法 |
| WO2019201195A1 (zh) | 2018-04-16 | 2019-10-24 | 上海岸阔医药科技有限公司 | 预防或治疗肿瘤疗法副作用的方法 |
| US20200046703A1 (en) * | 2018-08-09 | 2020-02-13 | Asymmetric Therapeutics, Llc | Compositions and methods for treatment of the side-effects associated with administration of therapeutic agents |
| CA3242908A1 (en) | 2022-01-05 | 2023-07-13 | Asymmetric Therapeutics, Llc. | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PROLIFERATIVE SKIN DISORDERS AND OTHER SKIN CONDITIONS |
| KR20250056445A (ko) * | 2023-10-19 | 2025-04-28 | (주) 수파드엘릭사 | 수족증후군 또는 수족피부반응의 예방 또는 치료용 약학 조성물 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0278040B1 (de) | 1987-02-13 | 1991-08-14 | Pharm-Allergan Gmbh | Verwendung von Pteridinen und/oder Purinen oder eines Xanthinoxidase-Hemmers zur Herstellung eines Arzneimittels zur Behandlung von genetisch bedingten degenerativen Netzhauterkrankungen |
| GB9218711D0 (en) | 1992-09-04 | 1992-10-21 | Salim Aws S M | Skin cancer treatment |
| AU4974893A (en) | 1992-09-04 | 1994-03-29 | Aws Shakir Mustafa Salim | Skin treatment compositions containing dimethylsulphone and allopurinol or oxypurinol |
| JP3106817B2 (ja) | 1993-11-02 | 2000-11-06 | 富士電機株式会社 | 漏電遮断器 |
| US6284234B1 (en) | 1998-08-04 | 2001-09-04 | Johnson & Johnson Consumer Companies, Inc. | Topical delivery systems for active agents |
| US6060083A (en) | 1999-04-01 | 2000-05-09 | Topical Technologies, Inc. | Topical DMSO treatment for palmar-plantar erythrodysethesia |
| GB0013346D0 (en) * | 2000-06-01 | 2000-07-26 | Glaxo Group Ltd | Therapeutic benzamide derivatives |
| DE60117043T2 (de) | 2000-11-22 | 2006-07-13 | Rxkinetix, Inc., Louisville | Behandlung von mukositis |
| US7544348B2 (en) | 2001-02-15 | 2009-06-09 | Access Pharmaceuticals, Inc. | Liquid formulations for the prevention and treatment of mucosal diseases and disorders |
| SE0100873D0 (sv) * | 2001-03-13 | 2001-03-13 | Astrazeneca Ab | Method of treatment |
| ATE429947T1 (de) | 2001-08-29 | 2009-05-15 | Pharmakodex Ltd | Vorrichtung zur topischen verabreichung |
| KR100949318B1 (ko) | 2001-11-29 | 2010-03-23 | 사운드 파마슈티칼스 인코퍼레이티드 | 화학요법의 바람직하지 않은 작용을 개선하기 위한 방법과조성물 |
| DE10200578A1 (de) | 2002-01-09 | 2003-07-10 | Roehm Gmbh | Haft- und Bindemittel für dermale oder transdermale Therapiesysteme |
| US6979688B2 (en) | 2002-02-12 | 2005-12-27 | Ford John P | Treatment method against side-effects of chemotherapy |
| US20040214215A1 (en) | 2003-03-07 | 2004-10-28 | Yu Ruey J. | Bioavailability and improved delivery of alkaline pharmaceutical drugs |
| EP1631146A4 (en) | 2003-06-11 | 2006-12-06 | Novacea Inc | TREATMENT OF CANCER USING ACTIVE VITAMIN COMPOUNDS ASSOCIATED WITH RADIOTHERAPEUTIC AGENTS AND TREATMENTS |
| EP1631297A4 (en) | 2003-06-11 | 2007-09-05 | Novacea Inc | TREATMENT OF IMMUNOSTIC DISEASES WITH ACTIVE VITAMIN D COMPOUNDS ALONE OR IN COMBINATION WITH OTHER THERAPEUTICS |
| US20050148907A1 (en) | 2003-12-24 | 2005-07-07 | Gregory Skover | Treatment of skin using a benefit agent and an apparatus |
| JP4405326B2 (ja) | 2004-06-28 | 2010-01-27 | 株式会社東芝 | ランドリー機器 |
| PT1796660T (pt) | 2004-09-17 | 2017-02-13 | Biomas Ltd | Utilização de tricloro(dioxietileno-o,o¿)telurato de amónio (as101) para a inibição da enzima de conversão da interleucina-1 beta |
| DE602007004849D1 (de) | 2006-06-01 | 2010-04-01 | Nobera Pharma Sl | Verwendung von allopurinol zur behandlung von palmarer/plantarer erythrodysästhesie |
-
2009
- 2009-04-29 EP EP09382058A patent/EP2246057A1/en not_active Withdrawn
-
2010
- 2010-04-29 US US12/770,179 patent/US8623878B2/en not_active Expired - Fee Related
- 2010-04-29 PT PT107193146T patent/PT2424538E/pt unknown
- 2010-04-29 RU RU2011148355/15A patent/RU2543325C2/ru not_active IP Right Cessation
- 2010-04-29 RS RS20130462A patent/RS53005B/sr unknown
- 2010-04-29 ES ES10719314T patent/ES2434366T3/es active Active
- 2010-04-29 MX MX2011011529A patent/MX2011011529A/es active IP Right Grant
- 2010-04-29 JP JP2012507765A patent/JP6007101B2/ja not_active Expired - Fee Related
- 2010-04-29 PL PL10719314T patent/PL2424538T3/pl unknown
- 2010-04-29 NZ NZ595901A patent/NZ595901A/xx not_active IP Right Cessation
- 2010-04-29 AU AU2010243594A patent/AU2010243594A1/en not_active Abandoned
- 2010-04-29 DK DK10719314.6T patent/DK2424538T3/da active
- 2010-04-29 WO PCT/EP2010/055806 patent/WO2010125143A1/en not_active Ceased
- 2010-04-29 KR KR1020117028500A patent/KR20120049848A/ko not_active Abandoned
- 2010-04-29 BR BRPI1011971A patent/BRPI1011971A2/pt not_active IP Right Cessation
- 2010-04-29 SI SI201030402T patent/SI2424538T1/sl unknown
- 2010-04-29 CA CA2759085A patent/CA2759085C/en not_active Expired - Fee Related
- 2010-04-29 ME MEP-2013-127A patent/ME01567B/me unknown
- 2010-04-29 CN CN201080019054.2A patent/CN102421436B/zh not_active Expired - Fee Related
- 2010-04-29 HR HRP20131070AT patent/HRP20131070T1/hr unknown
- 2010-04-29 EP EP10719314.6A patent/EP2424538B1/en active Active
- 2010-04-30 AR ARP100101462A patent/AR076505A1/es unknown
-
2011
- 2011-10-23 IL IL215831A patent/IL215831A/en not_active IP Right Cessation
-
2013
- 2013-11-22 US US14/087,884 patent/US20140080845A1/en not_active Abandoned
-
2016
- 2016-09-14 AU AU2016228193A patent/AU2016228193A1/en not_active Abandoned