JP2012524523A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2012524523A5 JP2012524523A5 JP2012501380A JP2012501380A JP2012524523A5 JP 2012524523 A5 JP2012524523 A5 JP 2012524523A5 JP 2012501380 A JP2012501380 A JP 2012501380A JP 2012501380 A JP2012501380 A JP 2012501380A JP 2012524523 A5 JP2012524523 A5 JP 2012524523A5
- Authority
- JP
- Japan
- Prior art keywords
- cell
- expression cassette
- gluc
- substance
- human
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000004027 cell Anatomy 0.000 claims 13
- 108090000623 proteins and genes Proteins 0.000 claims 5
- 239000000126 substance Substances 0.000 claims 5
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 4
- 102000004169 proteins and genes Human genes 0.000 claims 4
- 241000963438 Gaussia <copepod> Species 0.000 claims 3
- 108060001084 Luciferase Proteins 0.000 claims 3
- 239000005089 Luciferase Substances 0.000 claims 3
- 210000005260 human cell Anatomy 0.000 claims 3
- 230000001105 regulatory effect Effects 0.000 claims 3
- 101001066158 Homo sapiens Growth arrest and DNA damage-inducible protein GADD45 alpha Proteins 0.000 claims 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
- 239000002537 cosmetic Substances 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 239000002778 food additive Substances 0.000 claims 1
- 235000013373 food additive Nutrition 0.000 claims 1
- 229940040511 liver extract Drugs 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0905410.7 | 2009-03-28 | ||
| GBGB0905410.7A GB0905410D0 (en) | 2009-03-28 | 2009-03-28 | Genotoxicity testing |
| PCT/GB2010/000581 WO2010112821A1 (en) | 2009-03-28 | 2010-03-26 | Genotoxicity testing |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012524523A JP2012524523A (ja) | 2012-10-18 |
| JP2012524523A5 true JP2012524523A5 (enExample) | 2013-05-16 |
Family
ID=40671920
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012501380A Pending JP2012524523A (ja) | 2009-03-28 | 2010-03-26 | 遺伝毒性試験 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20120035079A1 (enExample) |
| EP (1) | EP2411540A1 (enExample) |
| JP (1) | JP2012524523A (enExample) |
| CN (1) | CN102449168A (enExample) |
| AU (1) | AU2010231209A1 (enExample) |
| CA (1) | CA2755985A1 (enExample) |
| GB (1) | GB0905410D0 (enExample) |
| WO (1) | WO2010112821A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012137186A1 (en) | 2011-04-08 | 2012-10-11 | Anthem Biosciences Pvt Ltd | An in vitro method for high throughput screening of genotoxic agents in eukaryotic cells |
| CA2876402A1 (en) * | 2012-06-13 | 2013-12-19 | Merck Patent Gmbh | Protein expression analyses for identifying genotoxic compounds |
| CN102851388B (zh) * | 2012-09-29 | 2014-03-19 | 山东大学齐鲁医院 | 一种用于鉴别卵巢癌易感性的分子标记、试剂盒及其鉴别方法 |
| CN102864234B (zh) * | 2012-09-29 | 2014-03-19 | 山东大学齐鲁医院 | 一种用于鉴别卵巢癌易感性的分子标记 |
| CN105200069A (zh) * | 2015-10-16 | 2015-12-30 | 北京交通大学 | 基于rna聚合酶ⅰ的rsv微型复制基因组及其应用 |
| EP3516068B1 (en) * | 2016-09-19 | 2025-04-23 | University of Southern California | Non-radioactive cytotoxicity assays |
| EP3707273B1 (en) | 2017-11-08 | 2024-04-10 | Twinstrand Biosciences, Inc. | Reagents and adapters for nucleic acid sequencing and methods for making such reagents and adapters |
| RU2020130024A (ru) * | 2018-02-13 | 2022-03-14 | Твинстранд Биосайенсис, Инк. | Способы и реагенты для обнаружения и оценки генотоксичности |
| KR20210059694A (ko) | 2018-07-12 | 2021-05-25 | 트윈스트랜드 바이오사이언시스, 인코포레이티드 | 게놈 편집, 클론 팽창 및 연관된 분야를 규명하기 위한 방법 및 시약 |
| US11534504B2 (en) * | 2018-10-03 | 2022-12-27 | Promega Corporation | Compositions and methods for stabilizing coelenterazine and analogs and derivatives thereof |
| CN114606269B (zh) * | 2022-03-17 | 2024-02-23 | 国家食品安全风险评估中心 | 一种用于食品接触材料迁移物的遗传毒性的高通量检测方法及应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0411198D0 (en) * | 2004-05-20 | 2004-06-23 | Gentronix Ltd | Genotoxic testing |
| EP1929311B1 (de) * | 2005-09-26 | 2010-03-31 | Ulrich Loos | Verfahren zum nachweis von autoimmunantikörpern gegen den tsh-rezeptor und neue tsh- rezeptorchimären |
| CN101149327B (zh) * | 2007-11-06 | 2010-06-30 | 浙江大学 | 基于细胞显微图像信息的抗肿瘤药物评价和筛选方法 |
-
2009
- 2009-03-28 GB GBGB0905410.7A patent/GB0905410D0/en not_active Ceased
-
2010
- 2010-03-26 US US13/260,458 patent/US20120035079A1/en not_active Abandoned
- 2010-03-26 CN CN2010800231330A patent/CN102449168A/zh active Pending
- 2010-03-26 CA CA2755985A patent/CA2755985A1/en not_active Abandoned
- 2010-03-26 AU AU2010231209A patent/AU2010231209A1/en not_active Abandoned
- 2010-03-26 WO PCT/GB2010/000581 patent/WO2010112821A1/en not_active Ceased
- 2010-03-26 EP EP10723255A patent/EP2411540A1/en not_active Withdrawn
- 2010-03-26 JP JP2012501380A patent/JP2012524523A/ja active Pending
-
2013
- 2013-10-14 US US14/053,070 patent/US20140302512A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2012524523A5 (enExample) | ||
| Feng et al. | Conditional disruption of Axin1 leads to development of liver tumors in mice | |
| Kenneweg et al. | Long noncoding RNA-enriched vesicles secreted by hypoxic cardiomyocytes drive cardiac fibrosis | |
| Vollrath et al. | Role of Nrf2 in the regulation of the Mrp2 (ABCC2) gene | |
| Bunn et al. | Oxygen sensing and molecular adaptation to hypoxia | |
| Holla et al. | Molecular virology of hepatitis E virus | |
| Gálvez et al. | Distinct pathways regulate proapoptotic Nix and BNip3 in cardiac stress | |
| Ghosh et al. | Copper supplementation restores cytochrome c oxidase assembly defect in a mitochondrial disease model of COA6 deficiency | |
| Majumder et al. | A novel feedback loop regulates the response to endoplasmic reticulum stress via the cooperation of cytoplasmic splicing and mRNA translation | |
| Stoller et al. | Identification of a novel nuclear localization signal in Tbx1 that is deleted in DiGeorge syndrome patients harboring the 1223delC mutation | |
| Fu et al. | A Drosophila model system to assess the function of human monogenic podocyte mutations that cause nephrotic syndrome | |
| Tho et al. | Chk1 is essential for chemical carcinogen-induced mouse skin tumorigenesis | |
| JP2013523824A5 (enExample) | ||
| JP2014144959A5 (enExample) | ||
| JP2015505370A5 (enExample) | ||
| EP2368430A3 (en) | Transgenic fish and uses thereof | |
| GB0905410D0 (en) | Genotoxicity testing | |
| JP2014221834A5 (enExample) | ||
| Samanfar et al. | The sensitivity of the yeast, Saccharomyces cerevisiae, to acetic acid is influenced by DOM34 and RPL36A | |
| Burr et al. | Rap1a regulates cardiac fibroblast contraction of 3D diabetic collagen matrices by increased activation of the AGE/RAGE cascade | |
| Dallaire et al. | Expression profile of Caenorhabditis elegans mutant for the Werner syndrome gene ortholog reveals the impact of vitamin C on development to increase life span | |
| Spatola et al. | Nuclear and cytoplasmic WDR-23 isoforms mediate differential effects on GEN-1 and SKN-1 substrates | |
| Yang et al. | MicroRNA‐320 involves in the cardioprotective effect of insulin against myocardial ischemia by targeting survivin | |
| Kotta-Loizou et al. | Hepatitis C virus core+ 1/ARF protein decreases hepcidin transcription through an AP1 binding site | |
| Oishi et al. | Delayed cutaneous wound healing in Fam129b/Minerva-deficient mice |