JP2012520856A5 - - Google Patents
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- Publication number
- JP2012520856A5 JP2012520856A5 JP2012500272A JP2012500272A JP2012520856A5 JP 2012520856 A5 JP2012520856 A5 JP 2012520856A5 JP 2012500272 A JP2012500272 A JP 2012500272A JP 2012500272 A JP2012500272 A JP 2012500272A JP 2012520856 A5 JP2012520856 A5 JP 2012520856A5
- Authority
- JP
- Japan
- Prior art keywords
- opt
- tissue
- group
- light
- polymer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
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- 238000000034 method Methods 0.000 claims 13
- 229920000642 polymer Polymers 0.000 claims 8
- 239000002872 contrast media Substances 0.000 claims 6
- 206010028980 Neoplasm Diseases 0.000 claims 5
- 238000012634 optical imaging Methods 0.000 claims 5
- 239000008194 pharmaceutical composition Substances 0.000 claims 5
- 239000002202 Polyethylene glycol Substances 0.000 claims 4
- 230000005284 excitation Effects 0.000 claims 4
- 229920001223 polyethylene glycol Polymers 0.000 claims 4
- 125000000217 alkyl group Chemical group 0.000 claims 3
- 230000003287 optical effect Effects 0.000 claims 3
- 239000007787 solid Substances 0.000 claims 3
- 238000001727 in vivo Methods 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 125000002853 C1-C4 hydroxyalkyl group Chemical group 0.000 claims 1
- 125000003342 alkenyl group Chemical group 0.000 claims 1
- 125000004183 alkoxy alkyl group Chemical group 0.000 claims 1
- 125000000304 alkynyl group Chemical group 0.000 claims 1
- 150000001413 amino acids Chemical class 0.000 claims 1
- 238000000149 argon plasma sintering Methods 0.000 claims 1
- 125000000732 arylene group Chemical group 0.000 claims 1
- JPBGLQJDCUZXEF-UHFFFAOYSA-N chromenylium Chemical compound [O+]1=CC=CC2=CC=CC=C21 JPBGLQJDCUZXEF-UHFFFAOYSA-N 0.000 claims 1
- 125000000753 cycloalkyl group Chemical group 0.000 claims 1
- 125000002993 cycloalkylene group Chemical group 0.000 claims 1
- 238000004090 dissolution Methods 0.000 claims 1
- 238000001914 filtration Methods 0.000 claims 1
- 125000000524 functional group Chemical group 0.000 claims 1
- 150000002337 glycosamines Chemical class 0.000 claims 1
- 125000004474 heteroalkylene group Chemical group 0.000 claims 1
- 125000005549 heteroarylene group Chemical group 0.000 claims 1
- 238000011503 in vivo imaging Methods 0.000 claims 1
- 125000005647 linker group Chemical group 0.000 claims 1
- 238000004020 luminiscence type Methods 0.000 claims 1
- 238000013507 mapping Methods 0.000 claims 1
- 125000006853 reporter group Chemical group 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 238000001356 surgical procedure Methods 0.000 claims 1
- 230000002123 temporal effect Effects 0.000 claims 1
- ANRHNWWPFJCPAZ-UHFFFAOYSA-M thionine Chemical compound [Cl-].C1=CC(N)=CC2=[S+]C3=CC(N)=CC=C3N=C21 ANRHNWWPFJCPAZ-UHFFFAOYSA-M 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16153509P | 2009-03-19 | 2009-03-19 | |
| US61/161,535 | 2009-03-19 | ||
| PCT/EP2010/053619 WO2010106169A1 (en) | 2009-03-19 | 2010-03-19 | Optical imaging agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012520856A JP2012520856A (ja) | 2012-09-10 |
| JP2012520856A5 true JP2012520856A5 (https=) | 2013-05-02 |
Family
ID=42331047
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012500272A Withdrawn JP2012520856A (ja) | 2009-03-19 | 2010-03-19 | 光学イメージング剤 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20120114563A1 (https=) |
| EP (1) | EP2413976A1 (https=) |
| JP (1) | JP2012520856A (https=) |
| KR (1) | KR20110138246A (https=) |
| CN (1) | CN102438659A (https=) |
| AU (1) | AU2010224789A1 (https=) |
| BR (1) | BRPI1009346A2 (https=) |
| CA (1) | CA2755770A1 (https=) |
| MX (1) | MX2011009808A (https=) |
| RU (1) | RU2011138096A (https=) |
| WO (1) | WO2010106169A1 (https=) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201015806D0 (en) | 2010-09-21 | 2010-10-27 | Ge Healthcare As | Vascular imaging agents |
| EP3029027B1 (en) | 2010-12-21 | 2018-06-27 | Pierce Biotechnology, Inc. | Fluorescent compounds |
| US8889884B1 (en) | 2011-07-14 | 2014-11-18 | Pierce Biotechnology, Inc. | Phosphine derivatives of fluorescent compounds |
| CA2841249C (en) | 2011-07-29 | 2023-09-26 | Avelas Biosciences, Inc. | Selective delivery molecules and methods of use |
| US9249307B2 (en) | 2011-08-16 | 2016-02-02 | Pierce Biotechnology, Inc. | Benzocyanine compounds |
| GB201116733D0 (en) | 2011-09-28 | 2011-11-09 | Ge Healthcare As | Peptide margin imaging agents |
| US9751868B2 (en) | 2012-02-28 | 2017-09-05 | Pierce Biotechnology, Inc. | Benzocyanine compounds |
| WO2013130761A1 (en) | 2012-03-02 | 2013-09-06 | Pierce Biotechnology, Inc. | Indole derivatives as labeling dye for biomolecule |
| CN104470546B (zh) * | 2012-07-20 | 2018-02-27 | 佳能株式会社 | 化合物和含有所述化合物的光声成像造影剂 |
| JP6288970B2 (ja) * | 2012-07-20 | 2018-03-07 | キヤノン株式会社 | 化合物、および、前記化合物を有する光音響イメージング用造影剤 |
| US9676787B2 (en) | 2012-08-28 | 2017-06-13 | Pierce Biotechnology, Inc. | Benzopyrylium compounds |
| WO2014055253A1 (en) * | 2012-10-04 | 2014-04-10 | The General Hospital Corporation | Methods of synthesizing and using peg-like fluorochromes |
| WO2014115206A1 (ja) * | 2013-01-28 | 2014-07-31 | 独立行政法人科学技術振興機構 | 組織透明化方法、組織透明化試薬及び組織観察方法 |
| EA031930B1 (ru) | 2013-01-30 | 2019-03-29 | Авелас Байосайенсиз, Инк. | Молекула селективной доставки для визуализации злокачественной ткани |
| FR3001463B1 (fr) * | 2013-01-31 | 2015-02-20 | Commissariat Energie Atomique | Particules luminescentes de carbone, procede de preparation et utilisation |
| EP3052136A4 (en) * | 2013-10-02 | 2017-06-21 | University of Massachusetts | Surface functionalized, host-guest polymer nano-assemblies and methods thereof |
| US9416276B2 (en) | 2013-11-07 | 2016-08-16 | Canon Kabushiki Kaisha | Method for producing contrast agent |
| US10245329B2 (en) | 2014-09-08 | 2019-04-02 | Canon Kabushiki Kaisha | Composition having dye and conjugate of polyethyleneglycol and additive and contrast agent for photoacoustic imaging having the same |
| WO2016060277A1 (en) * | 2014-10-16 | 2016-04-21 | Canon Kabushiki Kaisha | Polymer, and contrast agent for photoacoustic imaging, including the polymer |
| US10398788B2 (en) | 2014-10-24 | 2019-09-03 | Canon Kabushiki Kaisha | Polymer and contrast agent for photoacoustic imaging including the polymer |
| JP6700750B2 (ja) | 2014-12-09 | 2020-05-27 | キヤノン株式会社 | 化合物、および、前記化合物を有する光学イメージング用造影剤 |
| WO2016097317A1 (en) * | 2014-12-19 | 2016-06-23 | Bracco Imaging Spa | Intra-operative imaging |
| US10383957B2 (en) | 2015-01-06 | 2019-08-20 | Anthony H. de Haas | Near-infrared fluorescent surgical dye markers |
| JP2017002000A (ja) * | 2015-06-12 | 2017-01-05 | キヤノン株式会社 | 化合物又はその薬学的に受容可能な塩、及び、前記化合物又はその薬学的に受容可能な塩を有する光音響イメージング用造影剤。 |
| JP6789636B2 (ja) | 2015-09-30 | 2020-11-25 | キヤノン株式会社 | 重合体、前記重合体を有する光音響イメージング用造影剤 |
| WO2017057653A1 (en) | 2015-09-30 | 2017-04-06 | Canon Kabushiki Kaisha | Conjugate of polysarcosine and nir contrast agent for photoacoustic imaging |
| CN105688230B (zh) * | 2016-02-02 | 2018-12-11 | 史春梦 | 七甲川吲哚花菁染料-聚乙二醇-叶酸复合物及制备方法和应用 |
| CN109054013A (zh) * | 2018-08-22 | 2018-12-21 | 东北大学 | 一种经修饰的吲哚菁绿及其制备方法 |
| CN109738387A (zh) * | 2018-12-29 | 2019-05-10 | 佛山科学技术学院 | 一种基于吲哚箐绿的光学相干层析成像方法和装置 |
| WO2025197935A1 (ja) * | 2024-03-19 | 2025-09-25 | 国立大学法人 東京大学 | 薬物－ポリマー複合体、医薬組成物、および薬物送達用ポリマー |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5622685A (en) | 1990-05-30 | 1997-04-22 | Deutches Krebsforchunszentrum Stiftung Des Offentlichen Rechts | Polyether-substituted porphyrin anti-tumor agents |
| DE4445065A1 (de) | 1994-12-07 | 1996-06-13 | Diagnostikforschung Inst | Verfahren zur In-vivo-Diagnostik mittels NIR-Strahlung |
| WO1998048838A1 (en) | 1997-04-29 | 1998-11-05 | Nycomed Imaging As | Compounds |
| GB2337523A (en) * | 1998-04-29 | 1999-11-24 | Nycomed Imaging As | Light imaging contrast agents |
| US20100143258A1 (en) * | 2008-12-05 | 2010-06-10 | General Electric Company | Tumor margin imaging agents |
-
2010
- 2010-03-19 CA CA2755770A patent/CA2755770A1/en not_active Abandoned
- 2010-03-19 BR BRPI1009346A patent/BRPI1009346A2/pt not_active IP Right Cessation
- 2010-03-19 RU RU2011138096/15A patent/RU2011138096A/ru not_active Application Discontinuation
- 2010-03-19 CN CN2010800225217A patent/CN102438659A/zh active Pending
- 2010-03-19 WO PCT/EP2010/053619 patent/WO2010106169A1/en not_active Ceased
- 2010-03-19 US US13/257,318 patent/US20120114563A1/en not_active Abandoned
- 2010-03-19 JP JP2012500272A patent/JP2012520856A/ja not_active Withdrawn
- 2010-03-19 EP EP10710834A patent/EP2413976A1/en not_active Withdrawn
- 2010-03-19 KR KR1020117024519A patent/KR20110138246A/ko not_active Withdrawn
- 2010-03-19 AU AU2010224789A patent/AU2010224789A1/en not_active Abandoned
- 2010-03-19 MX MX2011009808A patent/MX2011009808A/es not_active Application Discontinuation
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