JP2012519669A - 抗真菌剤を溶解する方法、および爪への塗布に適している、高濃度の抗真菌剤を含む組成物 - Google Patents

抗真菌剤を溶解する方法、および爪への塗布に適している、高濃度の抗真菌剤を含む組成物 Download PDF

Info

Publication number
JP2012519669A
JP2012519669A JP2011552461A JP2011552461A JP2012519669A JP 2012519669 A JP2012519669 A JP 2012519669A JP 2011552461 A JP2011552461 A JP 2011552461A JP 2011552461 A JP2011552461 A JP 2011552461A JP 2012519669 A JP2012519669 A JP 2012519669A
Authority
JP
Japan
Prior art keywords
water
antifungal agent
pharmaceutical composition
terbinafine
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2011552461A
Other languages
English (en)
Japanese (ja)
Inventor
クレール・マラール
ナタリー・ウィルコックス
Original Assignee
ガルデルマ・リサーチ・アンド・デヴェロップメント
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ガルデルマ・リサーチ・アンド・デヴェロップメント filed Critical ガルデルマ・リサーチ・アンド・デヴェロップメント
Publication of JP2012519669A publication Critical patent/JP2012519669A/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2011552461A 2009-03-06 2010-03-05 抗真菌剤を溶解する方法、および爪への塗布に適している、高濃度の抗真菌剤を含む組成物 Pending JP2012519669A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US20251609P 2009-03-06 2009-03-06
FR0951416 2009-03-06
FR0951416A FR2942716B1 (fr) 2009-03-06 2009-03-06 Methode de solubilisation d'agent antifongique et compositions a haute concentration en agent antifongique applicables sur l'ongle
US61/202,516 2009-03-06
PCT/EP2010/052817 WO2010100252A1 (en) 2009-03-06 2010-03-05 Method of dissolving antifungal agent, and compositions with a high concentration of antifungal agent, suitable for application to the nail

Publications (1)

Publication Number Publication Date
JP2012519669A true JP2012519669A (ja) 2012-08-30

Family

ID=41056884

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011552461A Pending JP2012519669A (ja) 2009-03-06 2010-03-05 抗真菌剤を溶解する方法、および爪への塗布に適している、高濃度の抗真菌剤を含む組成物

Country Status (11)

Country Link
EP (1) EP2403476A1 (zh)
JP (1) JP2012519669A (zh)
KR (1) KR20110121702A (zh)
CN (1) CN102341092A (zh)
AU (1) AU2010220266A1 (zh)
BR (1) BRPI1006666A2 (zh)
CA (1) CA2753638A1 (zh)
FR (1) FR2942716B1 (zh)
MX (1) MX2011009093A (zh)
RU (1) RU2011140574A (zh)
WO (1) WO2010100252A1 (zh)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090175810A1 (en) 2008-01-03 2009-07-09 Gareth Winckle Compositions and methods for treating diseases of the nail
US8039494B1 (en) 2010-07-08 2011-10-18 Dow Pharmaceutical Sciences, Inc. Compositions and methods for treating diseases of the nail
PL2672962T3 (pl) * 2011-02-11 2015-08-31 Moberg Pharma Ab Nowa kompozycja przeciwgrzybicza
US9446131B2 (en) 2013-01-31 2016-09-20 Merz Pharmaceuticals, Llc Topical compositions and methods for making and using same
US8778365B1 (en) 2013-01-31 2014-07-15 Merz Pharmaceuticals, Llc Topical compositions and methods for making and using same
US9452173B2 (en) 2013-01-31 2016-09-27 Merz Pharmaceuticals, Llc Topical compositions and methods for making and using same
US9433680B2 (en) 2013-01-31 2016-09-06 Merz Pharmaceuticals, Llc Topical compositions and methods for making and using same
SG11201602596UA (en) 2013-10-03 2016-04-28 Dow Pharmaceutical Sciences Stabilized efinaconazole compositions
EP3071295A4 (en) 2013-11-22 2017-05-31 Dow Pharmaceutical Sciences, Inc. Anti-infective methods, compositions, and devices
SG11201703184SA (en) * 2014-10-21 2017-05-30 Hexima Ltd A method of treatment

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0585929A (ja) * 1991-03-08 1993-04-06 L'oreal Sa 爪糸状菌症処置用皮フ病学的組成物中への親水性浸透剤 の使用及び相当する組成物
WO2008121709A1 (en) * 2007-03-30 2008-10-09 Transport Pharmaceuticals, Inc. Pharmaceutical formulations for iontophoretic delivery of an anti-fungal drug

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU219480B (hu) * 1991-05-23 2001-04-28 Novartis Ag. Eljárás gombás körömmegbetegségek ellen helyileg alkalmazható, allil-amin-származékot tartalmazó gyógyászati készítmények előállítására

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0585929A (ja) * 1991-03-08 1993-04-06 L'oreal Sa 爪糸状菌症処置用皮フ病学的組成物中への親水性浸透剤 の使用及び相当する組成物
WO2008121709A1 (en) * 2007-03-30 2008-10-09 Transport Pharmaceuticals, Inc. Pharmaceutical formulations for iontophoretic delivery of an anti-fungal drug

Also Published As

Publication number Publication date
CN102341092A (zh) 2012-02-01
FR2942716B1 (fr) 2011-04-15
MX2011009093A (es) 2011-09-27
RU2011140574A (ru) 2013-04-20
EP2403476A1 (en) 2012-01-11
WO2010100252A1 (en) 2010-09-10
CA2753638A1 (en) 2010-09-10
FR2942716A1 (fr) 2010-09-10
AU2010220266A1 (en) 2011-09-08
BRPI1006666A2 (pt) 2016-04-19
KR20110121702A (ko) 2011-11-08

Similar Documents

Publication Publication Date Title
JP2012519669A (ja) 抗真菌剤を溶解する方法、および爪への塗布に適している、高濃度の抗真菌剤を含む組成物
JP5529539B2 (ja) 医薬組成物
US10881672B2 (en) Pharmaceutical tetracycline composition for dermatological use
KR20100075476A (ko) 항진균 조성물
KR20150122719A (ko) 증진된 생체이용률을 갖는 코르티코스테로이드의 국소 제제
US20120328543A1 (en) Use of a cationic, advantageously amphoteric, surfactant for the preparation of an antifungal solution that can be applied to the nail
JPH0585929A (ja) 爪糸状菌症処置用皮フ病学的組成物中への親水性浸透剤 の使用及び相当する組成物
CA3020157C (en) Topical composition comprising tacrolimus
US20120309763A1 (en) Antifungal composition intended to be applied to a perforated nail
JPH06211651A (ja) 爪白癬治療用組成物
JP5033381B2 (ja) 外用医薬組成物
EP1526849B1 (en) Topical formulations containing ketoprofen stabilised with sulisobenzone
AU2004262934B2 (en) Topical composition comprising terbinafine and hydrocortisone
AU2020236525B2 (en) Stable topical compositions of Fenoldopam
WO2007086582A1 (ja) ２２－オキサ－１α,２５－ジヒドロキシビタミンＤ3を含有する水中油型乳剤性ローション剤およびそれを用いた皮膚疾患の治療方法
US20120309753A1 (en) Method of dissolving antifungal agent, and compositions with a high concentration of antifungal agent, suitable for application to the nail
JP4060347B2 (ja) ２２−オキサ−１α，２５−ジヒドロキシビタミンＤ３を含有する水中油型乳剤性ローション剤
JP7512365B2 (ja) 油性外用液
JP5460766B2 (ja) 外用医薬組成物
KR20240139048A (ko) 피부 질환 치료를 위한 유기 아민 pH 조절제를 갖는 룩소리티닙의 국소 제형
JP2014152135A (ja) 医薬組成物
KR20240101661A (ko) 자가 유화 수중유 마이크로에멀젼 또는 나노에멀젼 및 유화 조성물

Legal Events

Date Code Title Description
A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20130723

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20140114