JP2012518415A5 - - Google Patents

Download PDF

Info

Publication number
JP2012518415A5
JP2012518415A5 JP2011551266A JP2011551266A JP2012518415A5 JP 2012518415 A5 JP2012518415 A5 JP 2012518415A5 JP 2011551266 A JP2011551266 A JP 2011551266A JP 2011551266 A JP2011551266 A JP 2011551266A JP 2012518415 A5 JP2012518415 A5 JP 2012518415A5
Authority
JP
Japan
Prior art keywords
cells
item
pluripotent stem
stem cells
medium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2011551266A
Other languages
English (en)
Japanese (ja)
Other versions
JP2012518415A (ja
JP6189581B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2010/024881 external-priority patent/WO2010096746A1/en
Publication of JP2012518415A publication Critical patent/JP2012518415A/ja
Publication of JP2012518415A5 publication Critical patent/JP2012518415A5/ja
Application granted granted Critical
Publication of JP6189581B2 publication Critical patent/JP6189581B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2011551266A 2009-02-20 2010-02-22 幹細胞の分化のための方法および組成物 Active JP6189581B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15421009P 2009-02-20 2009-02-20
US61/154,210 2009-02-20
PCT/US2010/024881 WO2010096746A1 (en) 2009-02-20 2010-02-22 Methods and compositions for the differentiation of stem cells

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2015213836A Division JP2016019543A (ja) 2009-02-20 2015-10-30 幹細胞の分化のための方法および組成物
JP2017113273A Division JP6691509B2 (ja) 2009-02-20 2017-06-08 幹細胞の分化のための方法および組成物

Publications (3)

Publication Number Publication Date
JP2012518415A JP2012518415A (ja) 2012-08-16
JP2012518415A5 true JP2012518415A5 (enExample) 2013-04-04
JP6189581B2 JP6189581B2 (ja) 2017-08-30

Family

ID=42101531

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2011551266A Active JP6189581B2 (ja) 2009-02-20 2010-02-22 幹細胞の分化のための方法および組成物
JP2015213836A Pending JP2016019543A (ja) 2009-02-20 2015-10-30 幹細胞の分化のための方法および組成物
JP2017113273A Active JP6691509B2 (ja) 2009-02-20 2017-06-08 幹細胞の分化のための方法および組成物

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2015213836A Pending JP2016019543A (ja) 2009-02-20 2015-10-30 幹細胞の分化のための方法および組成物
JP2017113273A Active JP6691509B2 (ja) 2009-02-20 2017-06-08 幹細胞の分化のための方法および組成物

Country Status (5)

Country Link
US (1) US8557580B2 (enExample)
EP (1) EP2398897B1 (enExample)
JP (3) JP6189581B2 (enExample)
CA (1) CA2753208C (enExample)
WO (1) WO2010096746A1 (enExample)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2008307633C1 (en) 2007-09-28 2015-04-30 Celularity Inc. Tumor suppression using human placental perfusate and human placenta-derived intermediate natural killer cells
US8609417B2 (en) * 2009-04-13 2013-12-17 The Regents Of The University Of California Methods and compositions for stem cell cultures
WO2011106681A2 (en) 2010-02-25 2011-09-01 The Johns Hopkins University SMOOTH MUSCLE-LIKE CELLS (SMLCs) DERIVED FROM HUMAN PLURIPOTENT STEM CELLS
US20130071927A1 (en) * 2010-05-05 2013-03-21 Sydney Ivf Limited Media and methods for cell culture
US20120064040A1 (en) * 2010-06-03 2012-03-15 The Regents Of The University Of California Serum free culture medium and supplement
WO2012009422A1 (en) * 2010-07-13 2012-01-19 Anthrogenesis Corporation Methods of generating natural killer cells
US8765470B2 (en) 2010-08-04 2014-07-01 Cellular Dynamics International, Inc. Reprogramming immortalized B-cells to induced pluripotent stem cells
JP5597904B2 (ja) * 2010-09-10 2014-10-01 国立大学法人 東京大学 多能性幹細胞からの血液細胞分化に関する培養方法
US20130295669A1 (en) 2010-11-09 2013-11-07 Lonza Cologne Gmbh Method for controlling binding of cells to a substrate
GB2502704B (en) 2010-11-15 2019-12-04 Accelerated Biosciences Corp Generation of neural stem cells from human trophoblast stem cells
US20140045265A1 (en) * 2011-02-16 2014-02-13 Salk Institute For Biological Studies Robust and efficient differentiation of human pluripotent stem cells to multipotent vascular progenitors
WO2012115276A1 (en) 2011-02-23 2012-08-30 Kyoto University Method for producing dendritic cells from pluripotent stem cells
EP2697360A1 (en) * 2011-04-11 2014-02-19 Jaffar Ali Bin M. Abdullah Protein-free culture media products
LT2761065T (lt) * 2011-09-29 2018-01-10 Cellsnap, Llc Kompozicijos ir būdai toksigeniškumo testavimui
EP3653698B1 (en) 2011-12-01 2025-04-02 New York Stem Cell Foundation, Inc. Automated system for producing induced pluripotent stem cells or differentiated cells
US10428309B2 (en) 2011-12-01 2019-10-01 New York Stem Cell Foundation, Inc. Systems and methods for producing stem cells and differentiated cells
US9428732B2 (en) 2011-12-05 2016-08-30 Primorigen Biosciences, Inc. Compositions and methods for differentiating pluripotent stem cells into primitive blood cells and uses thereof
AU2013225946B2 (en) * 2012-02-29 2018-07-12 The Johns Hopkins University Method for guiding the derivation of endothelial cells from human pluripotent stem cells employing two-dimensional, feeder-free differentiation
MX2015006301A (es) 2012-11-21 2015-09-07 Merz Pharma Gmbh & Co Kgaa Medios y metodos para la determinacion de la actividad biologica de la neurotoxina botulinica.
CN105102611B (zh) 2012-11-30 2021-09-10 艾克塞利瑞提德生物技术公司 通过调节mir-124分化干细胞的方法
EP3973967A1 (en) 2012-12-21 2022-03-30 Astellas Institute for Regenerative Medicine Methods for production of platelets from pluripotent stem cells and compositions thereof
WO2014123879A1 (en) 2013-02-05 2014-08-14 Anthrogenesis Corporation Natural killer cells from placenta
US9506037B2 (en) 2013-03-15 2016-11-29 The Johns Hopkins University Self-organized vascular networks from human pluripotent stem cells in a synthetic matrix
EP2777703B1 (en) 2013-03-15 2016-09-14 Lonza Cologne GmbH Compositions and methods for enhancing the therapeutic potential of stem cells
US9994825B2 (en) 2013-03-15 2018-06-12 The Johns Hopkins University Self-organized vascular networks from human pluripotent stem cells in a synthetic matrix
PL3014267T3 (pl) 2013-06-28 2019-05-31 Merz Pharma Gmbh & Co Kgaa Środki i sposoby określania aktywności biologicznej polipeptydów neurotoksyny w komórkach
WO2015097920A1 (ja) * 2013-12-27 2015-07-02 京都府公立大学法人 角膜内皮細胞の細胞治療併用剤
US11352606B2 (en) * 2014-02-10 2022-06-07 The Johns Hopkins University Low oxygen tension enhances endothelial fate of human pluripotent stem cells
BR112016019104A2 (pt) 2014-02-19 2017-10-10 Merz Pharma Gmbh &Co Kgaa método para padronizar a sensibilidade de neurônios, método para a geração de neurônios, método para determinar a atividade biológica, uso de gt1b
CA2945393C (en) 2014-04-24 2021-03-23 Board Of Regents, The University Of Texas System Application of induced pluripotent stem cells to generate adoptive cell therapy products
SG11201704291QA (en) 2014-11-26 2017-06-29 Accelerated Biosciences Corp Induced hepatocytes and uses thereof
CN107207586B (zh) 2014-12-19 2021-07-13 莫茨药物股份两合公司 用于测定BoNT/E在细胞中的生物活性的装置和方法
US10626372B1 (en) 2015-01-26 2020-04-21 Fate Therapeutics, Inc. Methods and compositions for inducing hematopoietic cell differentiation
TWI704156B (zh) 2015-03-04 2020-09-11 德商曼茲法瑪股份有限公司 用於增進肉毒桿菌神經毒素進入細胞之特定攝取的方法
CN108473961B (zh) 2015-11-04 2022-11-29 菲特治疗公司 用于诱导造血细胞分化的方法和组合物
KR20250141836A (ko) 2015-11-04 2025-09-29 페이트 세러퓨틱스, 인코포레이티드 만능 세포의 유전자 조작
EP3690022A1 (en) 2016-05-18 2020-08-05 Keio University Cell culture medium for culturing organoid, culture method, and organoid
MX2020007071A (es) 2018-01-05 2020-11-11 Platelet Biogenesis Inc Composiciones y metodos para producir megacariocitos.
WO2020006539A1 (en) 2018-06-29 2020-01-02 Platelet Biogenesis, Inc. Compositions for drug delivery and methods of use thereof
CA3109546A1 (en) * 2018-09-07 2020-03-12 Wisconsin Alumni Research Foundation Generation of hematopoietic progenitor cells from human pluripotent stem cells
CN110438065B (zh) * 2019-07-25 2020-06-05 中山大学 一种诱导人诱导性多能干细胞分化为内皮祖细胞的方法
MX2022005892A (es) * 2019-11-14 2022-06-14 Amgen Inc Produccion de celulas precursoras hematopoyeticas.
CN115956117A (zh) * 2020-08-21 2023-04-11 Jsr株式会社 人类人工多能干细胞的培养方法、人类人工多能干细胞培养物、以及脑类器官的制造方法
WO2024018018A1 (fr) 2022-07-21 2024-01-25 Etablissement Francais Du Sang Utilisation d'un composé vitisine pour la production de cellules hématopoïétiques
WO2025126208A1 (en) * 2023-12-12 2025-06-19 Accellta Ltd. Media for maintaining, differentiating, or both, pluripotent stem cells

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3065499D1 (en) 1979-04-11 1983-12-15 Mitsui Petrochemical Ind Process for producing spherical carrier particles for olefin polymerisation catalyst, catalyst comprising such carrier particles, and use of such catalyst in olefin polymerisation
GB9807935D0 (en) * 1998-04-14 1998-06-10 Univ Edinburgh Lineage specific cells and progenitor cells
EP0986635A4 (en) 1997-01-10 2001-11-07 Life Technologies Inc SERUM SUBSTITUTE FOR EMBRYONIC STEM CELLS
DE60036540T2 (de) 1999-03-25 2008-07-03 Mitsubishi Tanabe Pharma Corp. Rho-kinase-inhibitoren für die vorbeugung oder behandlung von interstitieller pneumonie und pulmonaler fibrose
WO2000078351A1 (en) 1999-06-18 2000-12-28 Mitsubishi Pharma Corporation Osteogenesis promoters
JP4563573B2 (ja) * 2000-12-07 2010-10-13 株式会社カネカ 抗原およびこの抗原を識別するモノクローナル抗体
US6943172B2 (en) 2002-01-23 2005-09-13 Bayer Pharmaceuticals Corporation Rho-kinase inhibitors
US6664266B2 (en) 2002-03-14 2003-12-16 Children's Medical Center Corporation Axon regeneration with PKC inhibitiors
GB0206860D0 (en) 2002-03-22 2002-05-01 Glaxo Group Ltd Compounds
CA2785889A1 (en) 2002-04-22 2003-10-30 The Board Of Trustees Of The Leland Stanford Junior University Peptide inhibitors of protein kinase c
WO2004029200A2 (en) 2002-09-26 2004-04-08 Children's Medical Center Corporation Method of enhancing proliferation and/or hematopoietic differentiation of stem cells
US7442548B2 (en) 2004-09-08 2008-10-28 Wisconsin Alumni Research Foundation Culturing human embryonic stem cells in medium containing pipecholic acid and gamma amino butyric acid
ES2383813T3 (es) 2004-09-08 2012-06-26 Wisconsin Alumni Research Foundation Método de cultivo y cultivo de células madre embrionarias
WO2006050330A2 (en) 2004-11-01 2006-05-11 Wisconsin Alumni Research Foundation Platelets from stem cells
US7732445B2 (en) 2006-07-21 2010-06-08 Northwestern University Myosin light chain kinase inhibitor compounds, compostions and related methods of use
JP2008099662A (ja) * 2006-09-22 2008-05-01 Institute Of Physical & Chemical Research 幹細胞の培養方法
JP5419279B2 (ja) * 2007-01-17 2014-02-19 ウィスコンシン アラムニ リサーチ ファンデーション 改良された幹細胞の培養
EP2137296A2 (en) 2007-03-23 2009-12-30 Wisconsin Alumni Research Foundation Somatic cell reprogramming
JP2008307007A (ja) * 2007-06-15 2008-12-25 Bayer Schering Pharma Ag 出生後のヒト組織由来未分化幹細胞から誘導したヒト多能性幹細胞
KR20100059789A (ko) 2007-06-29 2010-06-04 셀룰러 다이내믹스 인터내셔널, 인코포레이티드 배아줄기세포 배양을 위한 자동화 방법 및 장치
WO2009135206A1 (en) * 2008-05-02 2009-11-05 Stem Cell Products, Inc. Method for production of mast cells from stem cells

Similar Documents

Publication Publication Date Title
JP2012518415A5 (enExample)
US20220228118A1 (en) Methods and materials for hematoendothelial differentiation of human pluripotent stem cells under defined conditions
JP6691509B2 (ja) 幹細胞の分化のための方法および組成物
CN105026551B (zh) 用于hUTC生长的营养富集培养基
US10100282B2 (en) Differentiation of pluripotent cells
JP2017148079A5 (enExample)
CN114174493A (zh) 使用带电表面从诱导多能干细胞产生多个谱系的方法
CN112553147B (zh) 一种促进肌肉干细胞增殖的生长因子组合物及其应用
KR100986149B1 (ko) 저 산소 배양액 조건을 이용한 배아 줄기 세포로부터유래된 배상체로부터 혈관 내피 전구 세포의 분화방법
CN110607277B (zh) 一种人类多能干细胞分化巨噬细胞的方法
CN109475582A (zh) 基因递送的改进方法
CN101684454B (zh) 一种定型内胚层细胞的制备和分离方法
TWI860972B (zh) 造血前驅細胞標記
CA3219496A1 (en) A method for producing blood progenitor and progenitor t cells, resulting cells and methods and uses thereof
CN120173879A (zh) 一种由多能干细胞向造血干祖细胞分化的培养基组合物、其使用方法和应用
US20240191189A1 (en) Reagents and methods for producing arterial hemogenic endothelium, hematopoietic progenitors, and lymphoid cells thereby
CN119614499B (zh) 一种高效激活nk细胞的试剂组合及其应用
CN117925521A (zh) 用于培养nk细胞激活剂及其应用
CN115896030A (zh) 诱导胚胎干细胞高效分化为巨核细胞的方法
CN118667760A (zh) 诱导多能干细胞分化为cd34+造血干/祖细胞的培养基组合
Wolfe The effect of shear stress on pluripotent stem cells