JP2012518409A - タンパク質の組み合わせを含有する細胞培養培地 - Google Patents

タンパク質の組み合わせを含有する細胞培養培地 Download PDF

Info

Publication number
JP2012518409A
JP2012518409A JP2011551225A JP2011551225A JP2012518409A JP 2012518409 A JP2012518409 A JP 2012518409A JP 2011551225 A JP2011551225 A JP 2011551225A JP 2011551225 A JP2011551225 A JP 2011551225A JP 2012518409 A JP2012518409 A JP 2012518409A
Authority
JP
Japan
Prior art keywords
albumin
cells
cell
protein
nutritional supplement
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2011551225A
Other languages
English (en)
Japanese (ja)
Other versions
JP2012518409A5 (enExample
Inventor
スティーブン・シー・ペティ
メアリー・エイ・フェルナンデス−サントス
ニン・フアン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Invitria Inc
Original Assignee
Ventria Bioscience Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42634446&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JP2012518409(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ventria Bioscience Inc filed Critical Ventria Bioscience Inc
Publication of JP2012518409A publication Critical patent/JP2012518409A/ja
Publication of JP2012518409A5 publication Critical patent/JP2012518409A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/79—Transferrins, e.g. lactoferrins, ovotransferrins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C12N5/0043—Medium free of human- or animal-derived components
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C12N5/0056—Xeno-free medium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C12N2500/10—Metals; Metal chelators
    • C12N2500/20—Transition metals
    • C12N2500/24—Iron; Fe chelators; Transferrin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C12N2500/10—Metals; Metal chelators
    • C12N2500/20—Transition metals
    • C12N2500/24—Iron; Fe chelators; Transferrin
    • C12N2500/25—Insulin-transferrin; Insulin-transferrin-selenium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/105—Insulin-like growth factors [IGF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/998—Proteins not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/02—Cells for production

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
JP2011551225A 2009-02-20 2010-02-18 タンパク質の組み合わせを含有する細胞培養培地 Pending JP2012518409A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15420409P 2009-02-20 2009-02-20
US61/154,204 2009-02-20
PCT/US2010/024626 WO2010096588A2 (en) 2009-02-20 2010-02-18 Cell culture media containing combinations of proteins

Publications (2)

Publication Number Publication Date
JP2012518409A true JP2012518409A (ja) 2012-08-16
JP2012518409A5 JP2012518409A5 (enExample) 2013-04-04

Family

ID=42634446

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011551225A Pending JP2012518409A (ja) 2009-02-20 2010-02-18 タンパク質の組み合わせを含有する細胞培養培地

Country Status (9)

Country Link
US (6) US20120315697A1 (enExample)
EP (1) EP2398896A4 (enExample)
JP (1) JP2012518409A (enExample)
KR (1) KR20120018827A (enExample)
CN (1) CN102369276B (enExample)
AU (1) AU2010215959A1 (enExample)
CA (1) CA2752729A1 (enExample)
SG (1) SG173469A1 (enExample)
WO (1) WO2010096588A2 (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013517776A (ja) * 2010-01-25 2013-05-20 ベントリア・バイオサイエンス タンパク質の生成を改善するための方法および組成物
JP2013524856A (ja) * 2010-05-07 2013-06-20 ファイブロセル テクノロジーズ， インコーポレイテッド 自己真皮線維芽細胞の投与単位処方物
JP2022531582A (ja) * 2019-05-10 2022-07-07 バイオソリューション・カンパニー・リミテッド 細胞外小胞を高濃度で培養するための細胞培養培地及びその細胞培養培地を使用した細胞外小胞高含有馴化培養液の製造方法

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG173469A1 (en) 2009-02-20 2011-09-29 Ventria Bioscience Cell culture media containing combinations of proteins
WO2011075686A2 (en) * 2009-12-18 2011-06-23 Ventria Bioscience Methods & compositions comprising heat shock proteins
CN102127164B (zh) * 2010-12-20 2013-01-30 武汉禾元生物科技有限公司 一种从水稻种子中提取重组人血清白蛋白的方法
CN102532254B (zh) * 2010-12-24 2015-06-24 武汉禾元生物科技股份有限公司 一种从水稻种子中分离纯化重组人血清白蛋白的方法
CN102766206A (zh) * 2012-07-02 2012-11-07 北京济福霖生物技术有限公司 一种改善缺铁性贫血的产品及其制备方法
CN102827810B (zh) * 2012-09-19 2015-03-11 北京京蒙高科干细胞技术有限公司 一种无动物源的脐血干细胞无血清培养基
CN103880947B (zh) 2012-12-21 2016-01-13 武汉禾元生物科技股份有限公司 一种分离纯化高纯度重组人血清白蛋白的层析方法
BR112015020977A2 (pt) 2013-03-08 2017-07-18 Axiom Foods Inc suplemento de proteína de arroz e métodos de uso do mesmo
US9820504B2 (en) 2013-03-08 2017-11-21 Axiom Foods, Inc. Rice protein supplement and methods of use thereof
WO2015006725A2 (en) * 2013-07-12 2015-01-15 Cedars-Sinai Medical Center Generation of induced pluripotent stem cells from normal human mammary epithelial cells
GB2545287A (en) 2013-12-20 2017-06-14 Harvard College Organomimetic devices and methods of use and manufacturing thereof
WO2016044721A1 (en) * 2014-09-19 2016-03-24 Regenerative Medical Solutions, Inc. Compositions and methods for differentiating stem cells into cell populations comprising beta-like cells
WO2017044979A2 (en) * 2015-09-11 2017-03-16 Ventria Bioscience Inc. Lactoferrin compositions and methods for modulation of t cell subtypes and treatment of autoimmune diseases
CA3010764A1 (en) * 2016-01-12 2017-07-20 Lonza Walkersville, Inc. Methods and vectors to produce vector free induced pluripotent stem cells
KR101928488B1 (ko) * 2016-01-15 2018-12-12 가톨릭대학교 산학협력단 페록시다신을 포함하는 무혈청 배지 첨가제 조성물 및 이의 이용
US11572545B2 (en) 2016-06-16 2023-02-07 Cedars-Sinai Medical Center Efficient method for reprogramming blood to induced pluripotent stem cells
US10221395B2 (en) 2016-06-16 2019-03-05 Cedars-Sinai Medical Center Efficient method for reprogramming blood to induced pluripotent stem cells
CN106916220A (zh) * 2017-02-15 2017-07-04 瑞柏生物（中国）股份有限公司 一种重组人血清白蛋白溶液及其制备方法
EP3634155A4 (en) 2017-05-12 2021-02-17 Axiom Foods Inc. RICE PRODUCTS AND SYSTEMS AND PROCESSES FOR THEIR PRODUCTION
WO2020210741A1 (en) * 2019-04-12 2020-10-15 FUJIFILM Irvine Scientific, Inc. Embryo culture media supplement
WO2020252388A1 (en) * 2019-06-14 2020-12-17 Just, Inc. In vitro avian food product
US12146156B2 (en) 2019-07-02 2024-11-19 The Wistar Institute Of Anatomy And Biology Use of LRP2 agonists for generating myeloid-derived suppressor cells
WO2021245711A1 (en) * 2020-06-05 2021-12-09 Orf Liftaekni Hf. Growth factor composition for cell culture-produced meat
US10894812B1 (en) 2020-09-30 2021-01-19 Alpine Roads, Inc. Recombinant milk proteins
US10947552B1 (en) 2020-09-30 2021-03-16 Alpine Roads, Inc. Recombinant fusion proteins for producing milk proteins in plants
EP4222167A1 (en) 2020-09-30 2023-08-09 Nobell Foods, Inc. Recombinant milk proteins and food compositions comprising the same
EP4259775A4 (en) * 2020-12-09 2024-11-13 Trustees of Tufts College Supplemented serum-free media for cultured meat production
CN115873790A (zh) * 2021-09-27 2023-03-31 金涌长生医学生物科技股份有限公司 一种蜕膜胎盘间充质干细胞及其在制备促进血管新生药物组合物中的用途
WO2023158627A2 (en) * 2022-02-15 2023-08-24 University Of Southern California Methods for derivation and propagation of avian pluripotent stem cells and applications thereof

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001299334A (ja) * 2000-04-20 2001-10-30 Sumitomo Bakelite Co Ltd 細胞培養液、細胞培養方法及びバイオアッセイ方法
JP2006342169A (ja) * 1995-05-25 2006-12-21 Delta Biotechnology Ltd 高純度アルブミンの製造
WO2007002762A2 (en) * 2005-06-28 2007-01-04 Ventria Bioscience Components of cell culture media produced from plant cells
JP2007509609A (ja) * 2003-10-02 2007-04-19 ザ、リージェンツ、オブ、ザ、ユニバーシティ、オブ、ミシガン 幹細胞拘束および骨形成を誘導するヒト前立腺癌細胞因子
JP2007231225A (ja) * 2006-03-03 2007-09-13 Jellice Co Ltd エンドトキシン含有量を低減したゼラチンの製造方法および低エンドトキシンゼラチン
WO2007137149A2 (en) * 2006-05-22 2007-11-29 Velcura Therapeutics, Inc. Use of cathepsin k antagonists in bone production
WO2009011139A1 (ja) * 2007-07-13 2009-01-22 Mitsubishi Tanabe Pharma Corporation 細胞の単離方法、細胞用無血清培養培地および細胞の培養方法

Family Cites Families (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4093612A (en) 1975-08-04 1978-06-06 Research Corporation Selective removal of albumin from blood fluids and compositions therefore
SE405549B (sv) 1975-10-09 1978-12-18 Pharmacia Fine Chemicals Ab Forfarande for isolering av albumin ur plasmaprodukter genom kromatografisk fraktionering
NL7708005A (nl) 1976-07-22 1978-01-24 Monsanto Co Werkwijze voor de bereiding van serumalbumine.
US4075197A (en) 1976-09-20 1978-02-21 Monsanto Company Serum albumin production
US4136094A (en) 1977-08-31 1979-01-23 The Regents Of The University Of Minnesota Preparation of intravenous human and animal gamma globulins and isolation of albumin
US4228154A (en) 1979-02-26 1980-10-14 Armour Pharmaceutical Company Purification of plasma albumin by ion exchange chromatography
FR2600076A1 (fr) 1986-06-12 1987-12-18 Fond Ctre Nal Transfusion Milieu de culture comportant de l'albumine humaine, procede de preparation d'un produit injectable a partir de ce milieu, produit obtenu et son utilisation, composition obtenue
NL8901932A (nl) 1989-07-26 1991-02-18 Mogen Int Produktie van heterologe eiwitten in planten of plantecellen.
US5250662A (en) 1989-10-05 1993-10-05 Alpha Therapeutic Corporation Albumin purification
US7091401B2 (en) 1991-02-22 2006-08-15 Sembiosys Genetics Inc. Expression of epidermal growth factor in plant seeds
FR2690444B1 (fr) 1992-04-22 1995-07-13 Rucheton Marcel Procede de preparation d'une solution d'albumine plasmatique purifiee.
US5534256A (en) * 1992-07-02 1996-07-09 University Of Saskatchewan Haemophilus somnus outer membrane protein extract enriched with iron-regulated proteins
JP3360315B2 (ja) 1992-07-31 2002-12-24 三菱ウェルファーマ株式会社 ヒト血清アルブミンの高度精製方法
DK114392D0 (da) 1992-09-17 1992-09-17 Kem En Tec As Isolering af biomolekyler
US5780594A (en) 1993-03-01 1998-07-14 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Biologically active protein fragments containing specific binding regions of serum albumin or related proteins
DK0658569T3 (da) 1993-12-17 2005-02-07 Mitsubishi Pharma Corp Fremgangsmåde til affarvning af humant serumalbumin
AUPM388494A0 (en) * 1994-02-16 1994-03-10 Csl Limited Process for removing endotoxins
CA2157219C (en) 1994-08-31 2010-10-05 Munehiro Noda Process for purifying recombinant human serum albumin
DE19538625C2 (de) 1995-10-17 1999-08-12 Sartorius Gmbh Verfahren zur Abtrennung von Albumin aus Serum durch Membranionenaustauschchromatographie
US5914022A (en) 1996-01-05 1999-06-22 Lowry; Patrick Ross Method and apparatus for monitoring and controlling electrodeposition of paint
AU2260097A (en) * 1996-03-12 1997-10-01 Life Technologies, Inc. Hematopoietic cell culture nutrient supplement
EP0947581A4 (en) 1996-08-08 2004-07-28 Mitsubishi Pharma Corp CULTURAL MEDIUM AND ITS USE.
EP0986635A4 (en) * 1997-01-10 2001-11-07 Life Technologies Inc SERUM SUBSTITUTE FOR EMBRYONIC STEM CELLS
AU746826B2 (en) 1997-02-13 2002-05-02 Regents Of The University Of California, The Production of mature proteins in plants
FR2762850B1 (fr) 1997-05-02 2000-02-11 Biocem Lactoferrines recombinantes, leurs procedes de production par les plantes ainsi que leurs utilisations
AU7984498A (en) * 1997-06-25 1999-01-04 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Serum-free cell growth medium
US5994507A (en) 1997-12-31 1999-11-30 Amersham Pharmacia Biotech Ab Method for binding albumin and means to be used in the method
US6406909B1 (en) 1998-07-10 2002-06-18 Chugai Seiyaku Kabushiki Kaisha Serum-free medium for culturing animal cells
PT1097211E (pt) 1998-07-10 2007-07-12 Calgene Llc Expressão de péptidos eucarióticos em plastos vegetais
GB9902000D0 (en) 1999-01-30 1999-03-17 Delta Biotechnology Ltd Process
AU7614600A (en) 1999-09-27 2001-04-30 Genentech Inc. Methods for making recombinant proteins using apoptosis inhibitors
CA2402066C (en) 2000-03-01 2015-09-29 Auburn University Plastid transformation vectors for expressing human proteins in plants
US6991824B2 (en) 2000-05-02 2006-01-31 Ventria Bioscience Expression of human milk proteins in transgenic plants
US7417178B2 (en) 2000-05-02 2008-08-26 Ventria Bioscience Expression of human milk proteins in transgenic plants
US7304208B2 (en) 2000-05-02 2007-12-04 Ventria Bioscience Expression of human serum albumin (HSA) in monocot seeds
US7138150B2 (en) 2000-05-02 2006-11-21 Ventria Bioscience Method of making an anti-infective composition for treating oral infections
US20030172403A1 (en) 2000-05-02 2003-09-11 Ning Huang Plant transcription factors and enhanced gene expression
US6787636B1 (en) 2000-07-14 2004-09-07 New Century Pharmaceuticals, Inc. Modified serum albumin with reduced affinity for nickel and copper
JP2005525081A (ja) 2001-06-05 2005-08-25 カレン ケイ． オオイシ 植物からの生物活性ミュラー管抑制物質を含むＴＧＦ−βタンパク質の遺伝子発現および産生法
SE526227C2 (sv) 2002-05-15 2005-08-02 North China Pharmaceutical Group Metod för rening av rekombinant humant serumalbumin
US6890736B1 (en) * 2002-09-20 2005-05-10 Immunex Corporation Methods for producing proteins in cultured cells
CA2410702A1 (en) 2002-11-26 2004-05-26 Illimar Altosaar Production of human granulocyte macrophage-colony stimulating factor (gm-csf) in the seeds of transgenic rice plants
US20040268431A1 (en) 2003-06-30 2004-12-30 The Chinese University Of Hong Kong Transgenic plant products comprising human granulocyte colony-stimulating factor and method for preparing the same
WO2005011367A1 (en) 2003-07-03 2005-02-10 University Of Central Florida A chloroplast transgenic approach to express and purify human serum albumin, a protein highly susceptible to proteolytic degradation
WO2005056578A2 (en) 2003-12-09 2005-06-23 Ventria Bioscience High-level expression of fusion polypeptides in plant seeds utilizing seed-storage proteins as fusion carriers
WO2005070120A2 (en) * 2004-01-09 2005-08-04 Serologicals Investment Company, Inc. Cell culture media
AU2005205314B2 (en) 2004-01-20 2010-12-09 Km Biologics Co., Ltd. Process for producing human serum albumin by heating in presence of divalent cation
US7531327B2 (en) 2004-07-23 2009-05-12 Immunomedics, Inc. Methods and compositions for increasing longevity and protein yield from a cell culture
US7537930B2 (en) 2004-07-23 2009-05-26 Immunomedics, Inc. Mammalian cell lines for increasing longevity and protein yield from a cell culture
WO2006066595A2 (en) 2004-12-22 2006-06-29 Novozymes A/S Recombinant production of serum albumin
US7585955B2 (en) 2005-03-03 2009-09-08 Florida State University Research Foundation, Inc Protein separation from a protein mixture
US20070078851A1 (en) 2005-10-05 2007-04-05 Grell Mathew L System and method for filtering search query results
DK2010565T3 (da) 2006-04-21 2012-05-29 Agency Science Tech & Res Fremgangsmåde til produktion af rekombinant protein i CHO-celler
CN1884517B (zh) 2006-06-08 2010-06-30 武汉禾元生物科技有限公司 利用谷物非储藏蛋白为融合载体在胚乳表达多肽的方法及应用
WO2008009641A1 (en) 2006-07-17 2008-01-24 Novozymes A/S Cell culture media
JP2010525789A (ja) 2007-01-08 2010-07-29 ミリポア・コーポレイション １つ又はそれ以上のきょう雑物の低下したレベルの存在下で組換えタンパク質を生産するための細胞培養法
SG173469A1 (en) 2009-02-20 2011-09-29 Ventria Bioscience Cell culture media containing combinations of proteins
WO2011075686A2 (en) 2009-12-18 2011-06-23 Ventria Bioscience Methods & compositions comprising heat shock proteins
SG182618A1 (en) 2010-01-25 2012-08-30 Ventria Bioscience Methods & compositions for improving protein production

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006342169A (ja) * 1995-05-25 2006-12-21 Delta Biotechnology Ltd 高純度アルブミンの製造
JP2001299334A (ja) * 2000-04-20 2001-10-30 Sumitomo Bakelite Co Ltd 細胞培養液、細胞培養方法及びバイオアッセイ方法
JP2007509609A (ja) * 2003-10-02 2007-04-19 ザ、リージェンツ、オブ、ザ、ユニバーシティ、オブ、ミシガン 幹細胞拘束および骨形成を誘導するヒト前立腺癌細胞因子
WO2007002762A2 (en) * 2005-06-28 2007-01-04 Ventria Bioscience Components of cell culture media produced from plant cells
JP2007231225A (ja) * 2006-03-03 2007-09-13 Jellice Co Ltd エンドトキシン含有量を低減したゼラチンの製造方法および低エンドトキシンゼラチン
WO2007137149A2 (en) * 2006-05-22 2007-11-29 Velcura Therapeutics, Inc. Use of cathepsin k antagonists in bone production
WO2009011139A1 (ja) * 2007-07-13 2009-01-22 Mitsubishi Tanabe Pharma Corporation 細胞の単離方法、細胞用無血清培養培地および細胞の培養方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JPN6014027669; Ｔｏｄｄ　Ｊ．　Ｍｅｎｋｈａｕｓ　ｅｔ　ａｌ．: 'Ｃｏｎｓｉｄｅｒａｔｉｏｎｓ　ｆｏｒ　ｔｈｅ　Ｒｅｃｏｖｅｒｙ　ｏｆ　Ｒｅｃｏｍｂｉｎａｎｔ　Ｐｒｏｔｅｉｎｓ　ｆｒｏｍ　Ｐｌａｎｔｓ' Ｂｉｏｔｅｃｈｎｏｌｏｇｙ　Ｐｒｏｇｒｅｓｓ Ｖｏｌ．２０, 2004, ｐ１００１-１０１４ *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013517776A (ja) * 2010-01-25 2013-05-20 ベントリア・バイオサイエンス タンパク質の生成を改善するための方法および組成物
JP2013524856A (ja) * 2010-05-07 2013-06-20 ファイブロセル テクノロジーズ， インコーポレイテッド 自己真皮線維芽細胞の投与単位処方物
JP2022531582A (ja) * 2019-05-10 2022-07-07 バイオソリューション・カンパニー・リミテッド 細胞外小胞を高濃度で培養するための細胞培養培地及びその細胞培養培地を使用した細胞外小胞高含有馴化培養液の製造方法
JP7602265B2 (ja) 2019-05-10 2024-12-18 バイオソリューション・カンパニー・リミテッド 細胞外小胞を高濃度で培養するための細胞培養培地及びその細胞培養培地を使用した細胞外小胞高含有馴化培養液の製造方法

Also Published As

Publication number Publication date
EP2398896A2 (en) 2011-12-28
US10618951B1 (en) 2020-04-14
CN102369276B (zh) 2015-02-04
US12286467B2 (en) 2025-04-29
US20250250323A1 (en) 2025-08-07
EP2398896A4 (en) 2013-02-20
US20220332794A1 (en) 2022-10-20
SG173469A1 (en) 2011-09-29
WO2010096588A2 (en) 2010-08-26
AU2010215959A1 (en) 2011-08-04
CA2752729A1 (en) 2010-08-26
US20120315697A1 (en) 2012-12-13
US20210221870A1 (en) 2021-07-22
US20200247871A1 (en) 2020-08-06
US10981974B2 (en) 2021-04-20
CN102369276A (zh) 2012-03-07
WO2010096588A3 (en) 2011-01-06
KR20120018827A (ko) 2012-03-05
US11492389B1 (en) 2022-11-08

Similar Documents

Publication Publication Date Title
US11492389B1 (en) Cell culture media containing combinations of proteins
US8609416B2 (en) Methods and compositions comprising heat shock proteins
JP2013517776A (ja) タンパク質の生成を改善するための方法および組成物
KR101733834B1 (ko) 소형 펩티드를 포함하는 세포 배양 배지
CN107922920B (zh) 补充牛磺酸的细胞培养基和使用方法
KR20240065185A (ko) 무혈청 세포 배양 배지
KR20080039885A (ko) 식물 세포로부터 생산된 세포 배양 배지의 성분
HK1178938A (en) Methods & compositions for improving protein production

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20130215

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20130215

RD04 Notification of resignation of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7424

Effective date: 20140120

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20140701

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20140930

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20141007

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20141031

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20141110

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20141128

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20141205

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20150324