JP2012517425A - 切断型シスチンノットタンパク質 - Google Patents

切断型シスチンノットタンパク質 Download PDF

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Publication number
JP2012517425A
JP2012517425A JP2011549107A JP2011549107A JP2012517425A JP 2012517425 A JP2012517425 A JP 2012517425A JP 2011549107 A JP2011549107 A JP 2011549107A JP 2011549107 A JP2011549107 A JP 2011549107A JP 2012517425 A JP2012517425 A JP 2012517425A
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JP
Japan
Prior art keywords
amino acid
acid sequence
protein
growth factor
amino acids
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JP2011549107A
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English (en)
Japanese (ja)
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JP2012517425A5 (https=
Inventor
ペーテル・ティンマーマン
ワウテル・コルネーリス・ピュアイク
ティルマン・マチャス・ハーケング
アリアン・ウィレム・グリッフィーウーン
Original Assignee
ペプスキャン・システムズ・ベー・フェー
ユニフェルシタイト・マーストリヒト
アカデミス・ジーケンハイス・マーストリヒト
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Application filed by ペプスキャン・システムズ・ベー・フェー, ユニフェルシタイト・マーストリヒト, アカデミス・ジーケンハイス・マーストリヒト filed Critical ペプスキャン・システムズ・ベー・フェー
Publication of JP2012517425A publication Critical patent/JP2012517425A/ja
Publication of JP2012517425A5 publication Critical patent/JP2012517425A5/ja
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18Feminine contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2011549107A 2009-02-06 2010-02-05 切断型シスチンノットタンパク質 Pending JP2012517425A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP09152305 2009-02-06
EP09152305.0 2009-02-06
PCT/NL2010/050053 WO2010090523A1 (en) 2009-02-06 2010-02-05 Truncated cystine-knot proteins

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2015150998A Division JP6215879B2 (ja) 2009-02-06 2015-07-30 切断型シスチンノットタンパク質

Publications (2)

Publication Number Publication Date
JP2012517425A true JP2012517425A (ja) 2012-08-02
JP2012517425A5 JP2012517425A5 (https=) 2014-12-11

Family

ID=40834444

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2011549107A Pending JP2012517425A (ja) 2009-02-06 2010-02-05 切断型シスチンノットタンパク質
JP2015150998A Expired - Fee Related JP6215879B2 (ja) 2009-02-06 2015-07-30 切断型シスチンノットタンパク質

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2015150998A Expired - Fee Related JP6215879B2 (ja) 2009-02-06 2015-07-30 切断型シスチンノットタンパク質

Country Status (8)

Country Link
US (1) US8772236B2 (https=)
EP (1) EP2393832B1 (https=)
JP (2) JP2012517425A (https=)
AU (1) AU2010211438B2 (https=)
CA (1) CA2751445C (https=)
ES (1) ES2545614T3 (https=)
NZ (1) NZ594481A (https=)
WO (1) WO2010090523A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2751445C (en) 2009-02-06 2018-06-19 Pepscan Systems B.V. Truncated cystine-knot proteins
US11078248B2 (en) 2010-03-19 2021-08-03 Lifenet Health BMP peptides and methods of use
JP5905446B2 (ja) 2010-03-24 2016-04-20 ライフネット ヘルス Bmp−4ペプチドおよび使用方法
UA112981C2 (uk) * 2011-04-11 2016-11-25 Елі Ліллі Енд Компані Варіант людського gdnf
CA2847527A1 (en) 2011-09-02 2013-03-07 Lifenet Health Bmp peptides & methods of use
CN105085652B (zh) * 2014-05-16 2021-06-22 中国人民解放军军事医学科学院生物工程研究所 血小板衍生生长因子b突变体、其制备方法及用途
CU24637B1 (es) * 2019-12-24 2022-12-12 Ct Ingenieria Genetica Biotecnologia Polipéptidos que comprenden mutantes del vegf-a humano con re-arreglos de puentes disulfuro y composiciones que los contienen

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002532113A (ja) * 1998-12-21 2002-10-02 ルードヴィッヒ・インスティテュート・フォア・キャンサー・リサーチ 切断vegf−dの抗体及びその利用法
JP2008505843A (ja) * 2003-06-16 2008-02-28 セルテック アール アンド ディー, インコーポレイテッド 骨鉱化作用を増進させるための組成物および方法
JP2008509087A (ja) * 2004-05-27 2008-03-27 アクセルロン ファーマ インコーポレーテッド Tgf抑制解除因子およびそれに関連する使用方法
WO2008146023A1 (en) * 2007-05-31 2008-12-04 Ark Therapeutics Ltd. Vegf-d mutants and their use

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0496833A4 (en) * 1989-10-18 1992-12-02 Creative Biomolecules, Inc. Biosynthetic constructs of tgf--g(b)
JP3762222B2 (ja) 1998-10-07 2006-04-05 ストライカー・コーポレーション 改変型TGF−βスーパーファミリータンパク質
US7105481B2 (en) * 1998-11-10 2006-09-12 Ludwig Institute For Cancer Research Method for stimulating connective tissue growth or wound healing
AU770899B2 (en) * 1998-11-10 2004-03-04 Licentia Ltd Platelet-derived growth factor D, DNA coding therefor, and uses thereof
EP1125905A1 (en) 2000-02-16 2001-08-22 Pepscan Systems B.V. Segment synthesis
EP1197755A1 (en) 2000-10-11 2002-04-17 Pepscan Systems B.V. Identification of protein binding sites
EP1452868A2 (en) 2003-02-27 2004-09-01 Pepscan Systems B.V. Method for selecting a candidate drug compound
CA2659225A1 (en) 2006-07-26 2008-01-31 Pepscan Systems B.V. Immunogenic compounds and protein mimics
CA2751445C (en) 2009-02-06 2018-06-19 Pepscan Systems B.V. Truncated cystine-knot proteins

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002532113A (ja) * 1998-12-21 2002-10-02 ルードヴィッヒ・インスティテュート・フォア・キャンサー・リサーチ 切断vegf−dの抗体及びその利用法
JP2008505843A (ja) * 2003-06-16 2008-02-28 セルテック アール アンド ディー, インコーポレイテッド 骨鉱化作用を増進させるための組成物および方法
JP2008509087A (ja) * 2004-05-27 2008-03-27 アクセルロン ファーマ インコーポレーテッド Tgf抑制解除因子およびそれに関連する使用方法
WO2008146023A1 (en) * 2007-05-31 2008-12-04 Ark Therapeutics Ltd. Vegf-d mutants and their use

Also Published As

Publication number Publication date
US8772236B2 (en) 2014-07-08
JP2015193662A (ja) 2015-11-05
CA2751445A1 (en) 2010-08-12
US20120231000A1 (en) 2012-09-13
WO2010090523A1 (en) 2010-08-12
CA2751445C (en) 2018-06-19
EP2393832B1 (en) 2015-07-08
NZ594481A (en) 2012-09-28
AU2010211438B2 (en) 2016-04-14
JP6215879B2 (ja) 2017-10-18
AU2010211438A1 (en) 2011-09-01
ES2545614T3 (es) 2015-09-14
EP2393832A1 (en) 2011-12-14

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