NZ594481A - Truncated cystine-knot proteins - Google Patents

Truncated cystine-knot proteins

Info

Publication number
NZ594481A
NZ594481A NZ594481A NZ59448110A NZ594481A NZ 594481 A NZ594481 A NZ 594481A NZ 594481 A NZ594481 A NZ 594481A NZ 59448110 A NZ59448110 A NZ 59448110A NZ 594481 A NZ594481 A NZ 594481A
Authority
NZ
New Zealand
Prior art keywords
amino acid
acid sequence
cystine
length
growth factor
Prior art date
Application number
NZ594481A
Other languages
English (en)
Inventor
Peter Timmerman
Wouter Cornelis Puijk
Tilman Mathias Hackeng
Arjan Willem Griffioen
Original Assignee
Pepscan Systems Bv
Univ Maastricht
Academisch Ziekenhuis Maastricht
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pepscan Systems Bv, Univ Maastricht, Academisch Ziekenhuis Maastricht filed Critical Pepscan Systems Bv
Publication of NZ594481A publication Critical patent/NZ594481A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18Feminine contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NZ594481A 2009-02-06 2010-02-05 Truncated cystine-knot proteins NZ594481A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09152305 2009-02-06
PCT/NL2010/050053 WO2010090523A1 (en) 2009-02-06 2010-02-05 Truncated cystine-knot proteins

Publications (1)

Publication Number Publication Date
NZ594481A true NZ594481A (en) 2012-09-28

Family

ID=40834444

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ594481A NZ594481A (en) 2009-02-06 2010-02-05 Truncated cystine-knot proteins

Country Status (8)

Country Link
US (1) US8772236B2 (https=)
EP (1) EP2393832B1 (https=)
JP (2) JP2012517425A (https=)
AU (1) AU2010211438B2 (https=)
CA (1) CA2751445C (https=)
ES (1) ES2545614T3 (https=)
NZ (1) NZ594481A (https=)
WO (1) WO2010090523A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2393832B1 (en) 2009-02-06 2015-07-08 Pepscan Systems BV Truncated cystine-knot proteins
US11078248B2 (en) 2010-03-19 2021-08-03 Lifenet Health BMP peptides and methods of use
CA2794165A1 (en) 2010-03-24 2011-09-29 Lifenet Health Bmp-4 peptides & methods of use
UA112981C2 (uk) * 2011-04-11 2016-11-25 Елі Ліллі Енд Компані Варіант людського gdnf
US20150064163A1 (en) * 2011-09-02 2015-03-05 Lifenet Health BMP Peptides & Methods of Use
CN105085652B (zh) * 2014-05-16 2021-06-22 中国人民解放军军事医学科学院生物工程研究所 血小板衍生生长因子b突变体、其制备方法及用途
CU24637B1 (es) * 2019-12-24 2022-12-12 Ct Ingenieria Genetica Biotecnologia Polipéptidos que comprenden mutantes del vegf-a humano con re-arreglos de puentes disulfuro y composiciones que los contienen

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2070393A1 (en) 1989-10-18 1991-04-19 Charles M. Cohen Biosynthetic constructs of tgf-beta
CA2345024C (en) * 1998-10-07 2009-05-19 Stryker Corporation Modified tgf-.beta. superfamily proteins
US7105481B2 (en) * 1998-11-10 2006-09-12 Ludwig Institute For Cancer Research Method for stimulating connective tissue growth or wound healing
ATE556090T1 (de) 1998-11-10 2012-05-15 Ludwig Inst Cancer Res Verkürzter, von blutplättchen abstammender wachstumsfaktor d, dafür kodierendes dns und deren verwendung
US20040009535A1 (en) * 1998-11-27 2004-01-15 Celltech R&D, Inc. Compositions and methods for increasing bone mineralization
WO2000037025A2 (en) * 1998-12-21 2000-06-29 Ludwig Institute For Cancer Research Antibodies to truncated vegf-d and uses thereof
EP1125905A1 (en) 2000-02-16 2001-08-22 Pepscan Systems B.V. Segment synthesis
EP1197755A1 (en) 2000-10-11 2002-04-17 Pepscan Systems B.V. Identification of protein binding sites
EP1452868A2 (en) 2003-02-27 2004-09-01 Pepscan Systems B.V. Method for selecting a candidate drug compound
AU2005250441A1 (en) * 2004-05-27 2005-12-15 Acceleron Pharma Inc. TGF derepressors and uses related thereto
JP2009544697A (ja) 2006-07-26 2009-12-17 ペプスキャン システムズ ベー.フェー. 免疫原性化合物及びタンパク質擬態物
GB0710457D0 (en) * 2007-05-31 2007-07-11 Ark Therapeutics Ltd Vegf Mutants
EP2393832B1 (en) 2009-02-06 2015-07-08 Pepscan Systems BV Truncated cystine-knot proteins

Also Published As

Publication number Publication date
JP6215879B2 (ja) 2017-10-18
US20120231000A1 (en) 2012-09-13
WO2010090523A1 (en) 2010-08-12
JP2012517425A (ja) 2012-08-02
CA2751445C (en) 2018-06-19
US8772236B2 (en) 2014-07-08
EP2393832A1 (en) 2011-12-14
JP2015193662A (ja) 2015-11-05
CA2751445A1 (en) 2010-08-12
EP2393832B1 (en) 2015-07-08
AU2010211438B2 (en) 2016-04-14
AU2010211438A1 (en) 2011-09-01
ES2545614T3 (es) 2015-09-14

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Effective date: 20200123

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