JP2012514573A5 - - Google Patents
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- Publication number
- JP2012514573A5 JP2012514573A5 JP2011544918A JP2011544918A JP2012514573A5 JP 2012514573 A5 JP2012514573 A5 JP 2012514573A5 JP 2011544918 A JP2011544918 A JP 2011544918A JP 2011544918 A JP2011544918 A JP 2011544918A JP 2012514573 A5 JP2012514573 A5 JP 2012514573A5
- Authority
- JP
- Japan
- Prior art keywords
- hydroxyapatite
- range
- reactant
- molar ratio
- silicate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229910052588 hydroxylapatite Inorganic materials 0.000 claims 11
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 claims 11
- 239000011575 calcium Substances 0.000 claims 6
- 239000000376 reactant Substances 0.000 claims 6
- 238000000034 method Methods 0.000 claims 5
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical group [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 claims 4
- 229910052710 silicon Inorganic materials 0.000 claims 4
- 239000001506 calcium phosphate Substances 0.000 claims 3
- 229910000389 calcium phosphate Inorganic materials 0.000 claims 3
- 235000011010 calcium phosphates Nutrition 0.000 claims 3
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical class [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 claims 3
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 claims 2
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 claims 2
- 238000001354 calcination Methods 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 239000011574 phosphorus Substances 0.000 claims 2
- 229910052698 phosphorus Inorganic materials 0.000 claims 2
- 239000010703 silicon Substances 0.000 claims 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 claims 1
- BPQQTUXANYXVAA-UHFFFAOYSA-N Orthosilicate Chemical compound [O-][Si]([O-])([O-])[O-] BPQQTUXANYXVAA-UHFFFAOYSA-N 0.000 claims 1
- 229910019142 PO4 Inorganic materials 0.000 claims 1
- 229910000147 aluminium phosphate Inorganic materials 0.000 claims 1
- 229910052586 apatite Inorganic materials 0.000 claims 1
- 239000003519 biomedical and dental material Substances 0.000 claims 1
- 229910052791 calcium Inorganic materials 0.000 claims 1
- AXCZMVOFGPJBDE-UHFFFAOYSA-L calcium dihydroxide Chemical compound [OH-].[OH-].[Ca+2] AXCZMVOFGPJBDE-UHFFFAOYSA-L 0.000 claims 1
- 239000000920 calcium hydroxide Substances 0.000 claims 1
- 229910001861 calcium hydroxide Inorganic materials 0.000 claims 1
- BRPQOXSCLDDYGP-UHFFFAOYSA-N calcium oxide Chemical compound [O-2].[Ca+2] BRPQOXSCLDDYGP-UHFFFAOYSA-N 0.000 claims 1
- 239000000292 calcium oxide Substances 0.000 claims 1
- ODINCKMPIJJUCX-UHFFFAOYSA-N calcium oxide Inorganic materials [Ca]=O ODINCKMPIJJUCX-UHFFFAOYSA-N 0.000 claims 1
- 238000006243 chemical reaction Methods 0.000 claims 1
- 239000013078 crystal Substances 0.000 claims 1
- 239000012535 impurity Substances 0.000 claims 1
- 229910052909 inorganic silicate Inorganic materials 0.000 claims 1
- 150000003961 organosilicon compounds Chemical class 0.000 claims 1
- VSIIXMUUUJUKCM-UHFFFAOYSA-D pentacalcium;fluoride;triphosphate Chemical class [F-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O VSIIXMUUUJUKCM-UHFFFAOYSA-D 0.000 claims 1
- 239000010452 phosphate Substances 0.000 claims 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims 1
- 239000002244 precipitate Substances 0.000 claims 1
- 230000001376 precipitating effect Effects 0.000 claims 1
- 238000001556 precipitation Methods 0.000 claims 1
- RMAQACBXLXPBSY-UHFFFAOYSA-N silicic acid Chemical compound O[Si](O)(O)O RMAQACBXLXPBSY-UHFFFAOYSA-N 0.000 claims 1
- 235000012239 silicon dioxide Nutrition 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0900269.2 | 2009-01-08 | ||
| GBGB0900269.2A GB0900269D0 (en) | 2009-01-08 | 2009-01-08 | Silicate-substituted hydroxyapatite |
| PCT/GB2009/002954 WO2010079316A1 (en) | 2009-01-08 | 2009-12-23 | Silicate- substituted hydroxyapatite |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012514573A JP2012514573A (ja) | 2012-06-28 |
| JP2012514573A5 true JP2012514573A5 (enExample) | 2013-02-14 |
| JP5740314B2 JP5740314B2 (ja) | 2015-06-24 |
Family
ID=40379325
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011544918A Active JP5740314B2 (ja) | 2009-01-08 | 2009-12-23 | ケイ酸塩置換ヒドロキシアパタイト |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US8545895B2 (enExample) |
| EP (1) | EP2381970B1 (enExample) |
| JP (1) | JP5740314B2 (enExample) |
| AU (1) | AU2009336612B8 (enExample) |
| CA (1) | CA2749018C (enExample) |
| DK (1) | DK2381970T3 (enExample) |
| ES (1) | ES2632171T3 (enExample) |
| GB (1) | GB0900269D0 (enExample) |
| HU (1) | HUE033614T2 (enExample) |
| PL (1) | PL2381970T3 (enExample) |
| PT (1) | PT2381970T (enExample) |
| SI (1) | SI2381970T1 (enExample) |
| WO (1) | WO2010079316A1 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201010761D0 (en) * | 2010-06-25 | 2010-08-11 | Univ Aberdeen | Bone graft system |
| JP5692587B2 (ja) * | 2011-03-14 | 2015-04-01 | 株式会社リコー | トナー、現像剤、画像形成方法及びプロセスカートリッジ |
| ES2399261B1 (es) * | 2011-09-13 | 2013-10-18 | Universidad De Vigo | Recubrimiento sintético de implante óseo. |
| GB201122405D0 (en) | 2011-12-23 | 2012-02-08 | Univ Aberdeen | Calcium phosphate material |
| RU2500840C1 (ru) * | 2012-07-16 | 2013-12-10 | Федеральное государственное автономное образовательное учреждение высшего профессионального образования "Белгородский государственный национальный исследовательский университет" | Способ получения нанокристаллического кремнийзамещенного гидроксиапатита |
| RU2507151C1 (ru) * | 2012-10-19 | 2014-02-20 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Национальный исследовательский Томский государственный университет" | Способ получения кремниймодифицированного гидроксиапатита с использованием свч-излучения |
| ES2399000B1 (es) * | 2012-12-12 | 2014-01-28 | Biotechnology Institute I Mas D S.L. | Método para producir una estructura porosa de polisfosfato cálcico |
| US9315425B2 (en) | 2013-10-28 | 2016-04-19 | Universiti Brunei Darussalam | Macroporous ceramic body, method of manufacture and uses thereof |
| US10238507B2 (en) | 2015-01-12 | 2019-03-26 | Surgentec, Llc | Bone graft delivery system and method for using same |
| DE102015101626B4 (de) * | 2015-02-04 | 2019-06-27 | Kulzer Gmbh | Beschichtung dentaler, prothetischer Oberflächen mit einer deutlichen Schicht eines synthetischen Hydroxyapatits |
| CN107470012B (zh) * | 2017-07-05 | 2020-04-07 | 昆明理工大学 | 一种磷灰石纯矿物的提取方法 |
| JP7033456B2 (ja) * | 2018-01-24 | 2022-03-10 | 太平洋セメント株式会社 | 歯科用ケイ酸カルシウム水和物系材料 |
| US11116647B2 (en) | 2018-04-13 | 2021-09-14 | Surgentec, Llc | Bone graft delivery system and method for using same |
| US10687828B2 (en) | 2018-04-13 | 2020-06-23 | Surgentec, Llc | Bone graft delivery system and method for using same |
| JP7373330B2 (ja) * | 2018-09-25 | 2023-11-02 | Ｄｏｗａエコシステム株式会社 | ヒドロキシアパタイトの製造方法 |
| US20230120190A1 (en) | 2020-01-29 | 2023-04-20 | Marcelo Rodrigues Teixeira | Oral composition with synergistic association of organic and inorganic components for full maintenance of oral health, process for obtaining and uses thereof |
| GB202012350D0 (en) | 2020-08-07 | 2020-09-23 | Sirakoss Ltd | Method of producing calcium-deficient silicate-substituted calcium phosphate apatite |
| JP7562137B2 (ja) * | 2020-11-17 | 2024-10-07 | 国立研究開発法人産業技術総合研究所 | シリカを担持したリン酸カルシウム結晶 |
| KR102340029B1 (ko) * | 2021-06-29 | 2021-12-16 | 이상진 | 나노 바이오 세라믹스를 함유한 항균 및 항바이러스 제품 |
| CN117281944A (zh) * | 2023-08-25 | 2023-12-26 | 武汉理工大学深圳研究院 | 一种有机/无机复合敷料的制备方法及其应用 |
Family Cites Families (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB395713A (en) | 1932-01-19 | 1933-07-19 | George Birch | Improvements in and relating to piston rings |
| DD238619A1 (de) | 1985-06-24 | 1986-08-27 | Univ Schiller Jena | Anorganische - organische verbundwerkstoffe fuer biomedizinische zwecke |
| US4693986A (en) | 1985-06-25 | 1987-09-15 | Orthomatrix, Inc. | Ceramic process and products |
| JP3218401B2 (ja) * | 1991-08-02 | 2001-10-15 | 日本化学工業株式会社 | 防錆顔料組成物 |
| FR2712726B1 (fr) * | 1993-07-15 | 1995-12-15 | Commissariat Energie Atomique | Procédé de conditionnement de déchets radioactifs utilisant des apatites silicatées comme matrice de confinement. |
| US20020136696A1 (en) | 1995-05-19 | 2002-09-26 | Dosuk D. Lee | Orthopedic and dental ceramic implants |
| US5989030A (en) | 1996-01-03 | 1999-11-23 | Suga; Shinichi | Dental implant |
| GB2316940A (en) | 1996-08-30 | 1998-03-11 | Queen Mary & Westfield College | Silicon-substituted hydroxyapatite |
| FI971385A0 (fi) | 1997-04-04 | 1997-04-04 | Bioxid Oy | Biokompatibel komposition, metoder foer dess framstaellning samt anvaendning daerav |
| GB9727049D0 (en) * | 1997-12-22 | 1998-02-18 | Abonetics Ltd | Method for the preparation of carbonated hydroxyapatite compositions |
| CA2318085C (en) | 1998-01-29 | 2012-05-01 | Millenium Biologix Inc. | A synthetic stabilized calcium phosphate biomaterial |
| GB9821663D0 (en) | 1998-10-05 | 1998-11-25 | Abonetics Ltd | Foamed ceramics |
| GB2363115A (en) | 2000-06-10 | 2001-12-12 | Secr Defence | Porous or polycrystalline silicon orthopaedic implants |
| JP4638979B2 (ja) | 2000-10-26 | 2011-02-23 | 宇部マテリアルズ株式会社 | ケイ酸含有アパタイト |
| US6921544B2 (en) * | 2001-03-06 | 2005-07-26 | Rutgers, The State University | Magnesium-substituted hydroxyapatites |
| EP1389978B1 (en) | 2001-05-01 | 2009-01-07 | Amedica Corporation | Radiolucent bone graft |
| CN1294885C (zh) | 2001-06-05 | 2007-01-17 | 江苏阳生生物工程有限公司 | 人体骨组织生物工程支架制品及其制备方法和用途 |
| EP1449818A4 (en) | 2001-10-21 | 2006-12-06 | Nat Inst Of Advanced Ind Scien | POROUS ARTICLE OF FRITTE CALCIUM PHOSPHATE, PROCESS FOR PRODUCTION THEREOF, AND ARTIFICIAL AND HISTOMORPHOLOGICAL SCAFFOLD USING THE SAME |
| DE10161827A1 (de) | 2001-12-15 | 2003-06-26 | Dot Gmbh | Verfahren zur Beschichtung eines Substrats mit Calciumphosphat |
| NZ537093A (en) | 2002-06-19 | 2006-01-27 | Dr | Hydraulic cement based on calcium phosphate for surgical use |
| KR100475828B1 (ko) | 2002-08-30 | 2005-03-10 | 요업기술원 | 산호 유래 인산칼슘계 다공체 및 그 제조방법 |
| SE525236C2 (sv) | 2002-10-31 | 2005-01-11 | Cerbio Tech Ab | Förfarande för framställning av strukturerade keramiska beläggningar och belagda anordningar framställda med detta förfarande |
| GB2395713A (en) | 2002-11-13 | 2004-06-02 | Univ Cambridge Tech | A synthetic bone material |
| WO2004071327A1 (en) | 2003-02-06 | 2004-08-26 | Pentron Clinical Technologies, Llc | Method of manufacturing dental posts, obturators and restorations |
| AU2004212942A1 (en) | 2003-02-14 | 2004-09-02 | Depuy Spine, Inc. | In-situ formed intervertebral fusion device |
| IL155866A0 (en) | 2003-05-12 | 2003-12-23 | Yissum Res Dev Co | Responsive polymeric system |
| US20050074877A1 (en) | 2003-07-28 | 2005-04-07 | Mao Jeremy Jian | Biological engineering of articular structures containing both cartilage and bone |
| US20050100578A1 (en) | 2003-11-06 | 2005-05-12 | Schmid Steven R. | Bone and tissue scaffolding and method for producing same |
| MY144221A (en) | 2004-03-03 | 2011-08-15 | Polynovo Biomaterials Pty Ltd | Biocompatible polymer compositions for dual or multistaged curing. |
| US7498043B2 (en) | 2004-04-07 | 2009-03-03 | Warsaw Orthopedic, Inc. | Silicon substituted oxyapatite |
| US8163030B2 (en) | 2004-05-06 | 2012-04-24 | Degradable Solutions Ag | Biocompatible bone implant compositions and methods for repairing a bone defect |
| AU2005260656B2 (en) | 2004-06-30 | 2011-09-22 | The Board Of Trustees Of The University Of Illinois | Poly (ethylene glycol) - diacrylate- (PEGDA) - crosslinked hydrogels comprising adipogenic mesenchymal stem cells |
| WO2006118554A1 (en) | 2005-05-02 | 2006-11-09 | Shanghai Institute Of Ceramics | A degradable, macroporous bioactive glass scaffold as well as its preparation and manufacturing methods |
| WO2007124511A2 (en) | 2006-04-25 | 2007-11-01 | Washington State University | Resorbable ceramics with controlled strength loss rates |
| US8916198B2 (en) | 2006-04-25 | 2014-12-23 | Washington State University | Mesoporous calcium silicate compositions and methods for synthesis of mesoporous calcium silicate for controlled release of bioactive agents |
| GB2457756A (en) * | 2008-01-09 | 2009-09-02 | Univ Aberdeen | Bioceramic calcium phosphosilicate compositions |
| GB0801935D0 (en) | 2008-02-01 | 2008-03-12 | Apatech Ltd | Porous biomaterial |
-
2009
- 2009-01-08 GB GBGB0900269.2A patent/GB0900269D0/en not_active Ceased
- 2009-12-23 ES ES09796031.4T patent/ES2632171T3/es active Active
- 2009-12-23 PT PT97960314T patent/PT2381970T/pt unknown
- 2009-12-23 DK DK09796031.4T patent/DK2381970T3/en active
- 2009-12-23 AU AU2009336612A patent/AU2009336612B8/en active Active
- 2009-12-23 PL PL09796031T patent/PL2381970T3/pl unknown
- 2009-12-23 CA CA2749018A patent/CA2749018C/en active Active
- 2009-12-23 HU HUE09796031A patent/HUE033614T2/hu unknown
- 2009-12-23 EP EP09796031.4A patent/EP2381970B1/en active Active
- 2009-12-23 SI SI200931688T patent/SI2381970T1/sl unknown
- 2009-12-23 WO PCT/GB2009/002954 patent/WO2010079316A1/en not_active Ceased
- 2009-12-23 JP JP2011544918A patent/JP5740314B2/ja active Active
-
2010
- 2010-01-05 US US12/652,110 patent/US8545895B2/en active Active
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