JP2012513758A5 - - Google Patents
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- Publication number
- JP2012513758A5 JP2012513758A5 JP2011543724A JP2011543724A JP2012513758A5 JP 2012513758 A5 JP2012513758 A5 JP 2012513758A5 JP 2011543724 A JP2011543724 A JP 2011543724A JP 2011543724 A JP2011543724 A JP 2011543724A JP 2012513758 A5 JP2012513758 A5 JP 2012513758A5
- Authority
- JP
- Japan
- Prior art keywords
- oligonucleotide
- sequence
- oligonucleotides
- complementary
- provider
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108091034117 Oligonucleotide Proteins 0.000 claims description 400
- 230000000295 complement effect Effects 0.000 claims description 172
- 239000002773 nucleotide Substances 0.000 claims description 160
- 125000003729 nucleotide group Chemical group 0.000 claims description 160
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 claims description 146
- 241000186781 Listeria Species 0.000 claims description 138
- 150000007523 nucleic acids Chemical class 0.000 claims description 136
- 108091028043 Nucleic acid sequence Proteins 0.000 claims description 74
- 108020004707 nucleic acids Proteins 0.000 claims description 63
- 102000039446 nucleic acids Human genes 0.000 claims description 63
- 238000000034 method Methods 0.000 claims description 59
- 108020004465 16S ribosomal RNA Proteins 0.000 claims description 53
- 241000588724 Escherichia coli Species 0.000 claims description 53
- 230000003321 amplification Effects 0.000 claims description 36
- 238000003199 nucleic acid amplification method Methods 0.000 claims description 36
- 238000003556 assay Methods 0.000 claims description 34
- 238000001514 detection method Methods 0.000 claims description 26
- UYTPUPDQBNUYGX-UHFFFAOYSA-N guanine Chemical compound O=C1NC(N)=NC2=C1N=CN2 UYTPUPDQBNUYGX-UHFFFAOYSA-N 0.000 claims description 24
- 229930024421 Adenine Natural products 0.000 claims description 12
- GFFGJBXGBJISGV-UHFFFAOYSA-N Adenine Chemical compound NC1=NC=NC2=C1N=CN2 GFFGJBXGBJISGV-UHFFFAOYSA-N 0.000 claims description 12
- 229960000643 adenine Drugs 0.000 claims description 12
- 241000186779 Listeria monocytogenes Species 0.000 claims description 4
- 241000206605 Brochothrix Species 0.000 claims description 3
- 239000000523 sample Substances 0.000 description 11
- RXNXLAHQOVLMIE-UHFFFAOYSA-N phenyl 10-methylacridin-10-ium-9-carboxylate Chemical compound C12=CC=CC=C2[N+](C)=C2C=CC=CC2=C1C(=O)OC1=CC=CC=C1 RXNXLAHQOVLMIE-UHFFFAOYSA-N 0.000 description 3
- 210000003705 ribosome Anatomy 0.000 description 2
- 239000012634 fragment Substances 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14165108P | 2008-12-30 | 2008-12-30 | |
| US61/141,651 | 2008-12-30 | ||
| PCT/US2009/069746 WO2010078374A1 (en) | 2008-12-30 | 2009-12-29 | Compositions, kits and related methods for the detection and/or monitoring of listeria |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014127931A Division JP2014168483A (ja) | 2008-12-30 | 2014-06-23 | Ｌｉｓｔｅｒｉａを検出およびモニターするための組成物、キットおよび関連する方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012513758A JP2012513758A (ja) | 2012-06-21 |
| JP2012513758A5 true JP2012513758A5 (enExample) | 2013-02-07 |
| JP5793085B2 JP5793085B2 (ja) | 2015-10-14 |
Family
ID=41682839
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011543724A Active JP5793085B2 (ja) | 2008-12-30 | 2009-12-29 | Ｌｉｓｔｅｒｉａを検出およびモニターするための組成物、キットおよび関連する方法 |
| JP2014127931A Withdrawn JP2014168483A (ja) | 2008-12-30 | 2014-06-23 | Ｌｉｓｔｅｒｉａを検出およびモニターするための組成物、キットおよび関連する方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014127931A Withdrawn JP2014168483A (ja) | 2008-12-30 | 2014-06-23 | Ｌｉｓｔｅｒｉａを検出およびモニターするための組成物、キットおよび関連する方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (4) | US8748133B2 (enExample) |
| EP (2) | EP2910647A1 (enExample) |
| JP (2) | JP5793085B2 (enExample) |
| AU (1) | AU2009335053B2 (enExample) |
| CA (1) | CA2746539A1 (enExample) |
| WO (1) | WO2010078374A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1907588B1 (en) * | 2005-07-26 | 2013-06-05 | The University of Medicine and Dentistry of New Jersey | Assays for resistance to echinocandin-class drugs |
| WO2010078374A1 (en) | 2008-12-30 | 2010-07-08 | Gen-Probe Incorporated | Compositions, kits and related methods for the detection and/or monitoring of listeria |
| US12203884B2 (en) | 2019-03-21 | 2025-01-21 | The United States Of America, As Represented By The Secretary Of Agriculture | Flow-through electrochemical detection system |
| US11371073B2 (en) | 2020-03-11 | 2022-06-28 | The United States Of America, As Represented By The Secretary Of Agriculture | Listeria detection |
| US12221651B2 (en) * | 2021-03-30 | 2025-02-11 | The United States Of America, As Represented By The Secretary Of Agriculture | Polynucleotide detection system |
Family Cites Families (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2422956A1 (fr) | 1978-04-13 | 1979-11-09 | Pasteur Institut | Procede de detection et de caracterisation d'un acide nucleique ou d'une sequence de celui-ci, et reactif enzymatique pour la mise en oeuvre de ce procede |
| US6414152B1 (en) | 1981-12-11 | 2002-07-02 | University Of Wales College Of Medicine Of Heath Park | Luminescent labelling material and procedures |
| FI63596C (fi) | 1981-10-16 | 1983-07-11 | Orion Yhtymae Oy | Mikrobdiagnostiskt foerfarande som grundar sig pao skiktshybridisering av nukleinsyror och vid foerfarandet anvaenda kombinationer av reagenser |
| US5288609A (en) | 1984-04-27 | 1994-02-22 | Enzo Diagnostics, Inc. | Capture sandwich hybridization method and composition |
| US6060237A (en) | 1985-02-26 | 2000-05-09 | Biostar, Inc. | Devices and methods for optical detection of nucleic acid hybridization |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4965188A (en) | 1986-08-22 | 1990-10-23 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme |
| US4751177A (en) | 1985-06-13 | 1988-06-14 | Amgen | Methods and kits for performing nucleic acid hybridization assays |
| US4800159A (en) | 1986-02-07 | 1989-01-24 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences |
| US5541308A (en) | 1986-11-24 | 1996-07-30 | Gen-Probe Incorporated | Nucleic acid probes for detection and/or quantitation of non-viral organisms |
| DE3708541A1 (de) | 1987-03-17 | 1988-10-13 | Agfa Gevaert Ag | Haertungsmittel fuer proteine, eine damit gehaertete bindemittelschicht und ein eine solche schicht enthaltendes fotografisches aufzeichnungsmaterial |
| US5089386A (en) * | 1987-09-11 | 1992-02-18 | Gene-Trak Systems | Test for listeria |
| US5585481A (en) | 1987-09-21 | 1996-12-17 | Gen-Probe Incorporated | Linking reagents for nucleotide probes |
| US5639604A (en) | 1987-09-21 | 1997-06-17 | Gen-Probe Incorporated | Homogeneous protection assay |
| US6004745A (en) | 1987-09-21 | 1999-12-21 | Gen-Probe Incorporated | Hybridization protection assay |
| US6031091A (en) | 1987-09-21 | 2000-02-29 | Gen-Probe Incorporated | Non-nucleotide linking reagents for nucleotide probes |
| US5185439A (en) | 1987-10-05 | 1993-02-09 | Gen-Probe Incorporated | Acridinium ester labelling and purification of nucleotide probes |
| US5030557A (en) | 1987-11-24 | 1991-07-09 | Ml Technology Venture | Means and method for enhancing nucleic acid hybridization |
| US5130238A (en) | 1988-06-24 | 1992-07-14 | Cangene Corporation | Enhanced nucleic acid amplification process |
| US5118801A (en) | 1988-09-30 | 1992-06-02 | The Public Health Research Institute | Nucleic acid process containing improved molecular switch |
| CA2002076A1 (en) | 1988-11-21 | 1990-05-21 | Brent A. Burdick | Diagnostic kit and method using a solid phase capture means for detecting nucleic acids |
| US5656207A (en) | 1989-06-24 | 1997-08-12 | Gen Probe Incorporated | Detecting or quantifying multiple analytes using labelling techniques |
| ATE282716T1 (de) | 1989-07-11 | 2004-12-15 | Gen Probe Inc | Verfahren zur amplifikation von nukleinsäuresequenzen |
| CA2020958C (en) | 1989-07-11 | 2005-01-11 | Daniel L. Kacian | Nucleic acid sequence amplification methods |
| US5455166A (en) | 1991-01-31 | 1995-10-03 | Becton, Dickinson And Company | Strand displacement amplification |
| US5539082A (en) | 1993-04-26 | 1996-07-23 | Nielsen; Peter E. | Peptide nucleic acids |
| US5270184A (en) | 1991-11-19 | 1993-12-14 | Becton, Dickinson And Company | Nucleic acid target generation |
| AU687352B2 (en) | 1992-06-08 | 1998-02-26 | Gen-Probe Incorporated | Preparation of nucleic acid from mononuclear cells |
| US5398491A (en) | 1992-10-13 | 1995-03-21 | Honda Giken Kogyo Kabushiki Kaisha | Lawn mower side discharge chute |
| US5925517A (en) | 1993-11-12 | 1999-07-20 | The Public Health Research Institute Of The City Of New York, Inc. | Detectably labeled dual conformation oligonucleotide probes, assays and kits |
| WO1995014768A2 (en) | 1993-11-29 | 1995-06-01 | Gen-Probe Incorporated | Method for extracting nucleic acids from a wide range of organisms |
| US5648211A (en) | 1994-04-18 | 1997-07-15 | Becton, Dickinson And Company | Strand displacement amplification using thermophilic enzymes |
| DE69535240T2 (de) | 1994-10-28 | 2007-06-06 | Gen-Probe Inc., San Diego | Zusammensetzungen und Verfahren für die gleichzeitige Detektion und Quantifizierung von einer Mehrheit spezifischer Nuklein Säure Sequenzen |
| US5731148A (en) | 1995-06-07 | 1998-03-24 | Gen-Probe Incorporated | Adduct protection assay |
| DE69732926T2 (de) * | 1996-02-28 | 2006-04-13 | bioMérieux B.V. | Primer und sonden zur amplifizierung, erkennung und typisierung von mycoplasma pneumoniae |
| WO1997032532A1 (en) | 1996-03-05 | 1997-09-12 | Vnus Medical Technologies, Inc. | Vascular catheter-based system for heating tissue |
| EP0912767B1 (en) | 1996-07-16 | 2006-09-13 | Gen-Probe Incorporated | Methods for detecting and amplifying nucleic acid sequences using modified oligonucleotides having increased target specific tm |
| US5786218A (en) | 1996-08-16 | 1998-07-28 | Zeneca Limited | Method for monitoring solid phase reactions |
| JP3756313B2 (ja) | 1997-03-07 | 2006-03-15 | 武 今西 | 新規ビシクロヌクレオシド及びオリゴヌクレオチド類縁体 |
| US6534273B2 (en) | 1997-05-02 | 2003-03-18 | Gen-Probe Incorporated | Two-step hybridization and capture of a polynucleotide |
| DK0975807T3 (da) | 1997-05-02 | 2007-01-29 | Gen Probe Inc | To-trins hybridisering og indfangning af et polynukleotid |
| US6794499B2 (en) | 1997-09-12 | 2004-09-21 | Exiqon A/S | Oligonucleotide analogues |
| WO2000001850A2 (en) | 1998-07-02 | 2000-01-13 | Gen-Probe Incorporated | Molecular torches |
| US20050142584A1 (en) * | 2003-10-01 | 2005-06-30 | Willson Richard C. | Microbial identification based on the overall composition of characteristic oligonucleotides |
| AU2003288788B2 (en) | 2003-12-31 | 2007-02-15 | Adelaide Research & Innovation Pty Ltd | Vaccine comprising recombinant CLPP protein of Streptococcus pneumoniae |
| US7575864B2 (en) * | 2004-05-27 | 2009-08-18 | E.I. Du Pont De Nemours And Company | Method for the direct detection of diagnostic RNA |
| JP5020818B2 (ja) | 2004-07-01 | 2012-09-05 | ジェン−プローブ・インコーポレーテッド | 生物学的試料中の核酸を検出するための方法及び組成物 |
| US7696337B2 (en) | 2004-08-27 | 2010-04-13 | Gen-Probe Incorporated | Composition kits and methods for performing amplification reactions |
| US7964413B2 (en) | 2005-03-10 | 2011-06-21 | Gen-Probe Incorporated | Method for continuous mode processing of multiple reaction receptacles in a real-time amplification assay |
| EP1978111B1 (en) | 2007-04-02 | 2013-03-27 | Gen-Probe Incorporated | Compositions, kits and related methods for the detection and/or monitoring of Pseudomonas aeruginosa |
| EP2288726B1 (en) * | 2008-05-13 | 2012-06-13 | Gen-Probe Incorporated | Inactivatable target capture oligomers for use in the selective hybridization and capture of target nucleic acid sequences |
| WO2010078374A1 (en) | 2008-12-30 | 2010-07-08 | Gen-Probe Incorporated | Compositions, kits and related methods for the detection and/or monitoring of listeria |
-
2009
- 2009-12-29 WO PCT/US2009/069746 patent/WO2010078374A1/en not_active Ceased
- 2009-12-29 CA CA2746539A patent/CA2746539A1/en not_active Abandoned
- 2009-12-29 AU AU2009335053A patent/AU2009335053B2/en not_active Ceased
- 2009-12-29 EP EP15155337.7A patent/EP2910647A1/en not_active Withdrawn
- 2009-12-29 US US12/649,249 patent/US8748133B2/en active Active
- 2009-12-29 EP EP09795674.2A patent/EP2389449B1/en not_active Not-in-force
- 2009-12-29 JP JP2011543724A patent/JP5793085B2/ja active Active
-
2014
- 2014-05-02 US US14/268,107 patent/US9593383B2/en active Active
- 2014-06-23 JP JP2014127931A patent/JP2014168483A/ja not_active Withdrawn
-
2017
- 2017-02-03 US US15/424,052 patent/US10501812B2/en active Active
-
2019
- 2019-10-25 US US16/663,642 patent/US11198913B2/en active Active
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