JP2012513193A5 - - Google Patents

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Publication number
JP2012513193A5
JP2012513193A5 JP2011541487A JP2011541487A JP2012513193A5 JP 2012513193 A5 JP2012513193 A5 JP 2012513193A5 JP 2011541487 A JP2011541487 A JP 2011541487A JP 2011541487 A JP2011541487 A JP 2011541487A JP 2012513193 A5 JP2012513193 A5 JP 2012513193A5
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JP
Japan
Prior art keywords
antibody
seq
tfpi
amino acids
acid sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2011541487A
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English (en)
Japanese (ja)
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JP2012513193A (ja
JP5791512B2 (ja
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Publication date
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Priority claimed from PCT/EP2009/067566 external-priority patent/WO2010072687A1/en
Publication of JP2012513193A publication Critical patent/JP2012513193A/ja
Publication of JP2012513193A5 publication Critical patent/JP2012513193A5/ja
Application granted granted Critical
Publication of JP5791512B2 publication Critical patent/JP5791512B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2011541487A 2008-12-22 2009-12-18 組織因子経路阻害因子（ｔｆｐｉ）に対する抗体 Expired - Fee Related JP5791512B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP08172522 2008-12-22
EP08172522.8 2008-12-22
PCT/EP2009/067566 WO2010072687A1 (en) 2008-12-22 2009-12-18 Antibodies against tissue factor pathway inhibitor (tfpi)

Publications (3)

Publication Number Publication Date
JP2012513193A JP2012513193A (ja) 2012-06-14
JP2012513193A5 true JP2012513193A5 (enExample) 2012-12-13
JP5791512B2 JP5791512B2 (ja) 2015-10-07

Family

ID=42104649

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011541487A Expired - Fee Related JP5791512B2 (ja) 2008-12-22 2009-12-18 組織因子経路阻害因子（ｔｆｐｉ）に対する抗体

Country Status (6)

Country Link
US (2) US8618263B2 (enExample)
EP (1) EP2379599B1 (enExample)
JP (1) JP5791512B2 (enExample)
CN (1) CN102300876A (enExample)
TW (1) TW201026329A (enExample)
WO (1) WO2010072687A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2379600B2 (en) * 2008-12-22 2020-10-14 Novo Nordisk A/S Antibodies against tissue factor pathway inhibitor
SG183443A1 (en) 2010-03-01 2012-09-27 Bayer Healthcare Llc Optimized monoclonal antibodies against tissue factor pathway inhibitor (tfpi)
WO2012001087A1 (en) * 2010-06-30 2012-01-05 Novo Nordisk A/S Antibodies that are capable of specifically binding tissue factor pathway inhibitor
US9228022B2 (en) 2010-06-30 2016-01-05 Novo Nordisk A/S Antibodies that are capable of specifically binding tissue factor pathway inhibitor
WO2014140240A1 (en) 2013-03-15 2014-09-18 Novo Nordisk A/S Antibodies capable of specifically binding two epitopes on tissue factor pathway inhibitor
WO2014210546A1 (en) 2013-06-27 2014-12-31 University Of Washington Through Its Center For Commercialization Biocompatible polymeric system for targeted treatment of thrombotic and hemostatic disorders
CN105473619B (zh) * 2013-07-19 2020-12-15 诺和诺德股份有限公司 能够引起促凝血活性的识别组织因子途径抑制剂的n-末端部分的抗体
US11279771B2 (en) * 2014-09-17 2022-03-22 Novo Nordisk A/S Antibodies capable of binding two epitopes on tissue factor pathway inhibitor (1-161)
CN107428838B (zh) * 2015-02-25 2021-01-01 财团法人牧岩生命科学研究所 结合tfpi的新型抗体以及包含所述抗体的组合物
KR20230074843A (ko) 2015-08-19 2023-05-31 화이자 인코포레이티드 조직 인자 경로 억제제 항체 및 그의 용도
JP7289913B2 (ja) 2018-10-11 2023-06-12 ファイザー・インク Ｔｆｐｉアンタゴニストのための投薬レジメン
CN112442127A (zh) * 2019-08-29 2021-03-05 苏州康宁杰瑞生物科技有限公司 针对tfpi的单克隆抗体
WO2025124481A1 (zh) * 2023-12-13 2025-06-19 苏州康宁杰瑞生物科技有限公司 Tfpi抗体用于治疗血友病

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0539975A1 (en) 1991-10-31 1993-05-05 Teijin Limited Method for immunological assay of free lipoprotein-associated coagulation inhibitor (LACI) and kit therefor
JPH0875736A (ja) * 1994-09-06 1996-03-22 Chemo Sero Therapeut Res Inst ヒト組織因子凝固系インヒビターの定量法

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