JP2012512909A5 - - Google Patents
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- JP2012512909A5 JP2012512909A5 JP2011542518A JP2011542518A JP2012512909A5 JP 2012512909 A5 JP2012512909 A5 JP 2012512909A5 JP 2011542518 A JP2011542518 A JP 2011542518A JP 2011542518 A JP2011542518 A JP 2011542518A JP 2012512909 A5 JP2012512909 A5 JP 2012512909A5
- Authority
- JP
- Japan
- Prior art keywords
- umbilical cord
- cell population
- cord tissue
- derived
- tissue
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 210000004027 cell Anatomy 0.000 claims description 41
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- 210000003954 umbilical cord Anatomy 0.000 claims description 31
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- 208000004296 neuralgia Diseases 0.000 claims description 7
- 208000021722 neuropathic pain Diseases 0.000 claims description 7
- 208000002193 Pain Diseases 0.000 claims description 4
- 108090000623 proteins and genes Proteins 0.000 claims description 3
- 210000000130 stem cell Anatomy 0.000 claims description 3
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- 239000003814 drug Substances 0.000 claims 16
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- 108010035532 Collagen Proteins 0.000 claims 3
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- 206010010904 Convulsion Diseases 0.000 claims 3
- 229920001436 collagen Polymers 0.000 claims 3
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- 239000000017 hydrogel Substances 0.000 claims 3
- 108010073385 Fibrin Proteins 0.000 claims 2
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- BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 claims 2
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- 101710115997 Gamma-tubulin complex component 2 Proteins 0.000 description 1
- 102400001369 Heparin-binding EGF-like growth factor Human genes 0.000 description 1
- 101800001649 Heparin-binding EGF-like growth factor Proteins 0.000 description 1
- 101000924533 Homo sapiens Angiopoietin-2 Proteins 0.000 description 1
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- 101000955962 Homo sapiens Vacuolar protein sorting-associated protein 51 homolog Proteins 0.000 description 1
- 108010003272 Hyaluronate lyase Proteins 0.000 description 1
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- 108090001005 Interleukin-6 Proteins 0.000 description 1
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- 102100022647 Reticulon-1 Human genes 0.000 description 1
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- 102100032938 Telomerase reverse transcriptase Human genes 0.000 description 1
- 206010043276 Teratoma Diseases 0.000 description 1
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- 102100024596 Tumor necrosis factor alpha-induced protein 3 Human genes 0.000 description 1
- 102000005789 Vascular Endothelial Growth Factors Human genes 0.000 description 1
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- 210000001185 bone marrow Anatomy 0.000 description 1
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- 201000011510 cancer Diseases 0.000 description 1
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- 210000000349 chromosome Anatomy 0.000 description 1
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- 102000038379 digestive enzymes Human genes 0.000 description 1
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- 229960002773 hyaluronidase Drugs 0.000 description 1
- XKTZWUACRZHVAN-VADRZIEHSA-N interleukin-8 Chemical compound C([C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@@H](NC(C)=O)CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N1[C@H](CCC1)C(=O)N1[C@H](CCC1)C(=O)N[C@@H](C)C(=O)N[C@H](CC(O)=O)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@H](CC(O)=O)C(=O)N[C@H](CC=1C=CC(O)=CC=1)C(=O)N[C@H](CO)C(=O)N1[C@H](CCC1)C(N)=O)C1=CC=CC=C1 XKTZWUACRZHVAN-VADRZIEHSA-N 0.000 description 1
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- 238000002955 isolation Methods 0.000 description 1
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- 108020004999 messenger RNA Proteins 0.000 description 1
- 210000005087 mononuclear cell Anatomy 0.000 description 1
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- 230000001953 sensory effect Effects 0.000 description 1
- 238000011476 stem cell transplantation Methods 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 108010057210 telomerase RNA Proteins 0.000 description 1
- 230000002381 testicular Effects 0.000 description 1
- 238000005382 thermal cycling Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13916908P | 2008-12-19 | 2008-12-19 | |
| US61/139,169 | 2008-12-19 | ||
| PCT/US2009/068879 WO2010071862A1 (en) | 2008-12-19 | 2009-12-19 | Umbilical cord tissue derived cells for treating neuropathic pain and spasticity |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012512909A JP2012512909A (ja) | 2012-06-07 |
| JP2012512909A5 true JP2012512909A5 (https=) | 2012-07-19 |
| JP5646502B2 JP5646502B2 (ja) | 2014-12-24 |
Family
ID=41682583
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011542518A Expired - Fee Related JP5646502B2 (ja) | 2008-12-19 | 2009-12-19 | 神経因性疼痛を治療するための臍帯組織由来細胞 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20190105351A9 (https=) |
| EP (1) | EP2379087B1 (https=) |
| JP (1) | JP5646502B2 (https=) |
| CN (1) | CN102481321B (https=) |
| AU (1) | AU2009327382B2 (https=) |
| BR (1) | BRPI0923177A2 (https=) |
| CA (1) | CA2747757C (https=) |
| CY (1) | CY1116344T1 (https=) |
| DK (1) | DK2379087T3 (https=) |
| ES (1) | ES2520393T3 (https=) |
| PT (1) | PT2379087E (https=) |
| SI (1) | SI2379087T1 (https=) |
| WO (1) | WO2010071862A1 (https=) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8790637B2 (en) * | 2003-06-27 | 2014-07-29 | DePuy Synthes Products, LLC | Repair and regeneration of ocular tissue using postpartum-derived cells |
| WO2005001080A2 (en) | 2003-06-27 | 2005-01-06 | Ethicon, Incorporated | Postpartum-derived cells for use in treatment of disease of the heart and circulatory system |
| US8491883B2 (en) * | 2003-06-27 | 2013-07-23 | Advanced Technologies And Regenerative Medicine, Llc | Treatment of amyotrophic lateral sclerosis using umbilical derived cells |
| US7875272B2 (en) * | 2003-06-27 | 2011-01-25 | Ethicon, Incorporated | Treatment of stroke and other acute neuraldegenerative disorders using postpartum derived cells |
| US8518390B2 (en) | 2003-06-27 | 2013-08-27 | Advanced Technologies And Regenerative Medicine, Llc | Treatment of stroke and other acute neural degenerative disorders via intranasal administration of umbilical cord-derived cells |
| US9592258B2 (en) | 2003-06-27 | 2017-03-14 | DePuy Synthes Products, Inc. | Treatment of neurological injury by administration of human umbilical cord tissue-derived cells |
| CA2999420A1 (en) | 2005-09-27 | 2007-04-05 | Tissuetech, Inc. | Amniotic membrane preparations and purified compositions and methods of use |
| US9125906B2 (en) | 2005-12-28 | 2015-09-08 | DePuy Synthes Products, Inc. | Treatment of peripheral vascular disease using umbilical cord tissue-derived cells |
| PL2089511T3 (pl) | 2006-11-13 | 2015-02-27 | Depuy Synthes Products Llc | Rozrost in vitro komórek pochodzących z tkanki pępowinowej wykorzystujących mikronośniki |
| JP5323845B2 (ja) * | 2007-10-05 | 2013-10-23 | エシコン・インコーポレイテッド | ヒト臍帯組織由来細胞を用いた腎組織の修復および再建 |
| US8236538B2 (en) | 2007-12-20 | 2012-08-07 | Advanced Technologies And Regenerative Medicine, Llc | Methods for sterilizing materials containing biologically active agents |
| US10179900B2 (en) | 2008-12-19 | 2019-01-15 | DePuy Synthes Products, Inc. | Conditioned media and methods of making a conditioned media |
| CN102387807A (zh) | 2008-12-19 | 2012-03-21 | 先进科技及再生医学有限责任公司 | 肺部疾病和病症的治疗 |
| SG174551A1 (en) * | 2009-03-26 | 2011-10-28 | Ethicon Inc | Human umbilical cord tissue cells as therapy for alzheimer' s disease |
| WO2012149486A1 (en) | 2011-04-28 | 2012-11-01 | Tissuetech, Inc. | Methods of modulating bone remodeling |
| JP6104896B2 (ja) * | 2011-06-01 | 2017-03-29 | アントフロゲネシス コーポレーション | 胎盤幹細胞を使用する疼痛の治療 |
| ES2661587T3 (es) * | 2011-08-10 | 2018-04-02 | Depuy Synthes Products Llc | Tratamiento de enfermedad vascular periférica usando células derivadas de tejido del cordón umbilical |
| JP2015521630A (ja) * | 2012-06-26 | 2015-07-30 | ラスティー プロパティー ホールディングス プロプライエタリー リミテッド | 頭痛の頻度および／または重症度を下げるための組成物および方法 |
| EP2756754B1 (de) | 2013-01-17 | 2017-01-04 | Vita 34 Ag | Verfahren zur Behandlung von Nabelschnurgewebe, insbesondere im Zusammenhang mit der Konservierung des Gewebes |
| US10039792B1 (en) * | 2013-03-16 | 2018-08-07 | Brahm Holdings, Llc | Methods for the treatment of inflammation and pain using human birth tissue material composition |
| TW201603818A (zh) | 2014-06-03 | 2016-02-01 | 組織科技股份有限公司 | 組成物及方法 |
| SG11201700753YA (en) * | 2014-07-29 | 2017-02-27 | Ingeneron Inc | Method and apparatus for recovery of umbilical cord tissue derived regenerative cells and uses thereof |
| WO2016138025A2 (en) | 2015-02-23 | 2016-09-01 | Tissuetech, Inc. | Apparatuses and methods for treating ophthalmic diseases and disorders |
| US12551509B2 (en) | 2015-11-18 | 2026-02-17 | Lucina Patent Holdco, Llc | Acellular regenerative products and methods of their manufacture |
| CN106906180A (zh) * | 2016-12-28 | 2017-06-30 | 里程 | 一种具有生物活化作用的复合添加剂及其制备方法和用途 |
| CA3099387A1 (en) * | 2018-05-04 | 2019-11-07 | Figene, Llc | Pain-reducing effects of fibroblasts and treatment of pain |
| CN110772535A (zh) * | 2018-07-12 | 2020-02-11 | 南通大学 | 多系分化持续应激细胞在制备镇痛药物中的应用 |
| CA3286605A1 (en) | 2018-11-04 | 2025-11-29 | Fibrobiologics, Inc. | Treatment of cachexia using fibroblast cells and products thereof |
| WO2021092199A1 (en) * | 2019-11-08 | 2021-05-14 | Kansas State University Research Foundation | Isolation, preservation, and expansion of canine umbilical cord mesenchymal stromal cells |
| CN112190694B (zh) * | 2020-09-17 | 2023-11-10 | 南通大学 | 细胞因子活化素c在治疗神经病理性疼痛方面的应用 |
| EP4243840A4 (en) | 2020-11-13 | 2024-10-23 | Advanced Therapeutic Lab, Inc. | THERAPEUTIC PROCEDURES AND COMPOSITIONS USING STROMATIC VESSEL FRACTIONS DERIVED FROM ADIET TISSUE |
| US20220280573A1 (en) * | 2021-03-03 | 2022-09-08 | Axogen Corporation | Human umbilical cord-derived compositions and uses thereof for treating neuropathy |
| WO2022186946A1 (en) * | 2021-03-03 | 2022-09-09 | Axogen Corporation | Human umbilical cord-derived compositions and uses thereof for treating neuropathy |
| CN114561355B (zh) * | 2022-01-23 | 2023-04-11 | 四川大学华西医院 | 一种脊髓瘢痕组织细胞急性快速分离方法 |
| EP4561595A2 (en) * | 2022-07-26 | 2025-06-04 | Biostem Technologies, Inc. | Human umbilical cord compositions and methods for intra-articular therapy |
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-
2009
- 2009-12-19 BR BRPI0923177-3A patent/BRPI0923177A2/pt not_active Application Discontinuation
- 2009-12-19 CN CN200980156986.9A patent/CN102481321B/zh not_active Expired - Fee Related
- 2009-12-19 SI SI200931065T patent/SI2379087T1/sl unknown
- 2009-12-19 AU AU2009327382A patent/AU2009327382B2/en not_active Ceased
- 2009-12-19 JP JP2011542518A patent/JP5646502B2/ja not_active Expired - Fee Related
- 2009-12-19 ES ES09795654.4T patent/ES2520393T3/es active Active
- 2009-12-19 DK DK09795654.4T patent/DK2379087T3/da active
- 2009-12-19 PT PT97956544T patent/PT2379087E/pt unknown
- 2009-12-19 WO PCT/US2009/068879 patent/WO2010071862A1/en not_active Ceased
- 2009-12-19 EP EP09795654.4A patent/EP2379087B1/en not_active Not-in-force
- 2009-12-19 CA CA2747757A patent/CA2747757C/en active Active
- 2009-12-19 US US12/642,775 patent/US20190105351A9/en not_active Abandoned
-
2014
- 2014-11-18 CY CY20141100961T patent/CY1116344T1/el unknown
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