JP2012506695A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2012506695A5 JP2012506695A5 JP2011523864A JP2011523864A JP2012506695A5 JP 2012506695 A5 JP2012506695 A5 JP 2012506695A5 JP 2011523864 A JP2011523864 A JP 2011523864A JP 2011523864 A JP2011523864 A JP 2011523864A JP 2012506695 A5 JP2012506695 A5 JP 2012506695A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- antibody
- heavy chain
- chain variable
- variable region
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9047208P | 2008-08-20 | 2008-08-20 | |
| US61/090,472 | 2008-08-20 | ||
| US9723208P | 2008-09-16 | 2008-09-16 | |
| US61/097,232 | 2008-09-16 | ||
| PCT/US2009/053425 WO2010021874A2 (en) | 2008-08-20 | 2009-08-11 | Engineered anti-il-13 antibodies, compositions, methods and uses |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012182330A Division JP2013005805A (ja) | 2008-08-20 | 2012-08-21 | 改変された抗ｉｌ−１３抗体、組成物、方法、及び使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012506695A JP2012506695A (ja) | 2012-03-22 |
| JP2012506695A5 true JP2012506695A5 (https=) | 2012-09-27 |
Family
ID=41707613
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011523864A Pending JP2012506695A (ja) | 2008-08-20 | 2009-08-11 | 改変された抗ｉｌ−１３抗体、組成物、方法、及び使用 |
| JP2012182330A Pending JP2013005805A (ja) | 2008-08-20 | 2012-08-21 | 改変された抗ｉｌ−１３抗体、組成物、方法、及び使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012182330A Pending JP2013005805A (ja) | 2008-08-20 | 2012-08-21 | 改変された抗ｉｌ−１３抗体、組成物、方法、及び使用 |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US8399630B2 (https=) |
| EP (1) | EP2328615A2 (https=) |
| JP (2) | JP2012506695A (https=) |
| KR (1) | KR20110043786A (https=) |
| CN (1) | CN102264391A (https=) |
| AR (1) | AR073088A1 (https=) |
| AU (1) | AU2009283008A1 (https=) |
| BR (1) | BRPI0917370A2 (https=) |
| CA (1) | CA2734645A1 (https=) |
| CO (1) | CO6341573A2 (https=) |
| CR (1) | CR20110152A (https=) |
| EA (1) | EA201170357A1 (https=) |
| EC (1) | ECSP11010840A (https=) |
| IL (1) | IL211087A0 (https=) |
| MX (1) | MX2011001909A (https=) |
| NI (1) | NI201100040A (https=) |
| NZ (1) | NZ591098A (https=) |
| UY (1) | UY32060A (https=) |
| WO (1) | WO2010021874A2 (https=) |
| ZA (1) | ZA201102081B (https=) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7306925B2 (en) | 2001-11-09 | 2007-12-11 | Vanderbilt University | Phage antibodies to radiation-inducible neoantigens |
| US7906102B2 (en) | 2001-10-03 | 2011-03-15 | Vanderbilt University | Ligands to radiation-induced molecules |
| US8399630B2 (en) * | 2008-08-20 | 2013-03-19 | Centocor Ortho Biotech Inc. | Engineered anti-IL-13 antibodies, compositions, methods and uses |
| GB0904214D0 (en) * | 2009-03-11 | 2009-04-22 | Ucb Pharma Sa | Biological products |
| ES2826883T3 (es) * | 2009-10-14 | 2021-05-19 | Janssen Biotech Inc | Métodos de maduración por afinidad de anticuerpos |
| JOP20210044A1 (ar) * | 2010-12-30 | 2017-06-16 | Takeda Pharmaceuticals Co | الأجسام المضادة لـ cd38 |
| WO2013019730A1 (en) | 2011-07-29 | 2013-02-07 | The Washington University | Antibodies to tip-1 and grp78 |
| PL3489261T3 (pl) | 2012-08-24 | 2021-08-16 | The Regents Of The University Of California | Przeciwciała i szczepionki do stosowania w leczeniu nowotworów z ekspresją ROR1 i w hamowaniu przerzutu |
| CA2904969C (en) | 2013-03-13 | 2025-06-17 | Imaginab, Inc. | DIFFERENTIATION CLUSTER ANTIGEN-BINDING GENETIC CONSTRUCTIONS 8 |
| US10449261B2 (en) | 2014-07-24 | 2019-10-22 | Washington University | Compositions targeting radiation-induced molecules and methods of use thereof |
| WO2017027325A1 (en) | 2015-08-07 | 2017-02-16 | Imaginab, Inc. | Antigen binding constructs to target molecules |
| KR102460040B1 (ko) | 2016-04-27 | 2022-11-01 | 애브비 인코포레이티드 | 항-il-13 항체를 이용한 il-13 활성이 유해한 질환의 치료 방법 |
| IL299099B2 (en) | 2016-06-27 | 2025-07-01 | Univ California | Cancer treatment combinations |
| MA45674A (fr) | 2016-07-15 | 2019-05-22 | Takeda Pharmaceuticals Co | Méthodes et matériaux permettant d'évaluer une réponse à des traitements de déplétion de plasmoblastes et de plasmocytes |
| US10610104B2 (en) | 2016-12-07 | 2020-04-07 | Progenity, Inc. | Gastrointestinal tract detection methods, devices and systems |
| WO2018147960A1 (en) | 2017-02-08 | 2018-08-16 | Imaginab, Inc. | Extension sequences for diabodies |
| US11352436B2 (en) | 2017-02-10 | 2022-06-07 | Washington University | Antibodies to TIP1 and methods of use thereof |
| WO2018183932A1 (en) | 2017-03-30 | 2018-10-04 | Progenity Inc. | Treatment of a disease of the gastrointestinal tract with a il-13 inhibitor |
| KR20210006321A (ko) | 2018-01-12 | 2021-01-18 | 다케다 야쿠힌 고교 가부시키가이샤 | 항-cd38 항체의 피하 투여 |
| US20220249814A1 (en) | 2018-11-19 | 2022-08-11 | Progenity, Inc. | Methods and devices for treating a disease with biotherapeutics |
| CN121197633A (zh) | 2019-12-13 | 2025-12-26 | 比特比德科有限责任公司 | 用于将治疗剂递送至胃肠道的可摄取装置 |
| GB201919062D0 (en) * | 2019-12-20 | 2020-02-05 | Ucb Biopharma Sprl | Antibody |
| BR112022018682A2 (pt) * | 2020-03-18 | 2023-02-14 | Memorial Sloan Kettering Cancer Center | Anticorpos anti-ceramida |
| TW202525846A (zh) | 2023-08-25 | 2025-07-01 | 美商普羅特歐拉吉克適美國公司 | 抗ｉｌ—１３多特異性抗體構築體及其用途 |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU217099B (hu) | 1991-03-29 | 1999-11-29 | Elf Sanofi Sa. | Eljárás citokin típusú aktivitással rendelkező fehérje, azt kódoló rekombináns DNS-szekvencia és a megfelelő transzformált sejtek és mikroorganizmusok előállítására |
| US5596072A (en) * | 1992-08-21 | 1997-01-21 | Schering Corporation | Method of refolding human IL-13 |
| US5710023A (en) | 1996-03-01 | 1998-01-20 | Genetics Institute, Inc. | IL-13 cytokine receptor chain |
| US7078494B1 (en) | 1996-03-01 | 2006-07-18 | Genetics Institute, Llc | Antibodies to human IL-13bc and methods of their use in inhibiting IL-13 binding |
| US6664227B1 (en) | 1996-03-01 | 2003-12-16 | Genetics Institute, Llc | Treatment of fibrosis by antagonism of IL-13 and IL-13 receptor chains |
| GB9625899D0 (en) | 1996-12-13 | 1997-01-29 | Glaxo Group Ltd | Substances and their uses |
| US6743604B1 (en) | 1996-12-13 | 2004-06-01 | Smithkline Beecham Corporation | Substances and their uses |
| US7553487B2 (en) | 1998-12-14 | 2009-06-30 | Genetics Institute, Llc | Method and compositions for treating asthma |
| US6472147B1 (en) | 1999-05-25 | 2002-10-29 | The Scripps Research Institute | Methods for display of heterodimeric proteins on filamentous phage using pVII and pIX, compositions, vectors and combinatorial libraries |
| AU2000278349A1 (en) | 1999-09-28 | 2001-04-30 | Genaissance Pharmaceuticals, Inc. | Drug target isogenes: polymorphisms in the interleukin 13 gene |
| US20030103978A1 (en) | 2000-02-23 | 2003-06-05 | Amgen Inc. | Selective binding agents of osteoprotegerin binding protein |
| MXPA03011158A (es) | 2001-06-07 | 2004-02-27 | Wyeth Corp | Estructura de solucion de il - 13 y sus usos. |
| MXPA05000511A (es) | 2001-07-12 | 2005-09-30 | Jefferson Foote | Anticuepros super humanizados. |
| US20040023337A1 (en) * | 2001-10-26 | 2004-02-05 | Heavner George A. | IL-13 mutein proteins, antibodies, compositions, methods and uses |
| KR100872210B1 (ko) * | 2003-04-23 | 2008-12-05 | 메다렉스, 인코포레이티드 | 인터페론 알파 수용체-1 (ｉｆｎａｒ-1)에 대한 인체화항체 |
| GB0407315D0 (en) * | 2003-07-15 | 2004-05-05 | Cambridge Antibody Tech | Human antibody molecules |
| SG10201404273QA (en) | 2003-12-23 | 2014-10-30 | Genentech Inc | Novel anti-il 13 antibodies and uses thereof |
| EP1713441A2 (en) | 2004-02-12 | 2006-10-25 | Nektar Therapeutics | Interleukin-13 antagonist powders, spray-dried particles, and methods |
| AR049390A1 (es) | 2004-06-09 | 2006-07-26 | Wyeth Corp | Anticuerpos contra la interleuquina-13 humana y usos de los mismos |
| US7501121B2 (en) | 2004-06-17 | 2009-03-10 | Wyeth | IL-13 binding agents |
| US20070048785A1 (en) | 2004-06-09 | 2007-03-01 | Lin Laura L | Anti-IL-13 antibodies and complexes |
| JP2008520684A (ja) | 2004-11-17 | 2008-06-19 | アブジェニックス・インコーポレーテッド | Ｉｌ−１３に対する完全ヒトモノクローナル抗体 |
| RU2421464C2 (ru) | 2005-10-21 | 2011-06-20 | Новартис Аг | Человеческие антитела к il-13 и их терапевтическое применение |
| CA2914170C (en) | 2006-09-08 | 2018-10-30 | Abbvie Bahamas Ltd. | Interleukin-13 binding proteins |
| PT2094728E (pt) | 2006-10-26 | 2013-05-27 | Janssen Biotech Inc | Métodos de adaptação de anticorpos monoclonais ao ser humano |
| WO2008073463A2 (en) * | 2006-12-11 | 2008-06-19 | Wyeth | Methods and compositions for treating and monitoring treatment of il-13-associated disorders |
| JP2011507519A (ja) | 2007-12-19 | 2011-03-10 | セントコア・オーソ・バイオテツク・インコーポレーテツド | ｐＩＸ又はｐＶＩＩへの融合を介したヒトデノボｐＩＸファージディスプレイライブラリの設計及び作製、ベクター、抗体、及び方法 |
| US8399630B2 (en) * | 2008-08-20 | 2013-03-19 | Centocor Ortho Biotech Inc. | Engineered anti-IL-13 antibodies, compositions, methods and uses |
-
2009
- 2009-08-11 US US13/058,453 patent/US8399630B2/en not_active Expired - Fee Related
- 2009-08-11 BR BRPI0917370A patent/BRPI0917370A2/pt not_active Application Discontinuation
- 2009-08-11 WO PCT/US2009/053425 patent/WO2010021874A2/en not_active Ceased
- 2009-08-11 MX MX2011001909A patent/MX2011001909A/es not_active Application Discontinuation
- 2009-08-11 EP EP09808611A patent/EP2328615A2/en not_active Withdrawn
- 2009-08-11 CN CN2009801424060A patent/CN102264391A/zh active Pending
- 2009-08-11 JP JP2011523864A patent/JP2012506695A/ja active Pending
- 2009-08-11 EA EA201170357A patent/EA201170357A1/ru unknown
- 2009-08-11 AU AU2009283008A patent/AU2009283008A1/en not_active Abandoned
- 2009-08-11 NZ NZ591098A patent/NZ591098A/xx not_active IP Right Cessation
- 2009-08-11 KR KR1020117006418A patent/KR20110043786A/ko not_active Withdrawn
- 2009-08-11 CA CA2734645A patent/CA2734645A1/en not_active Abandoned
- 2009-08-12 US US12/539,630 patent/US8323646B2/en not_active Expired - Fee Related
- 2009-08-19 AR ARP090103185A patent/AR073088A1/es unknown
- 2009-08-19 UY UY0001032060A patent/UY32060A/es unknown
-
2011
- 2011-02-06 IL IL211087A patent/IL211087A0/en unknown
- 2011-02-17 CO CO11019113A patent/CO6341573A2/es not_active Application Discontinuation
- 2011-02-18 EC EC2011010840A patent/ECSP11010840A/es unknown
- 2011-02-18 NI NI201100040A patent/NI201100040A/es unknown
- 2011-03-18 ZA ZA2011/02081A patent/ZA201102081B/en unknown
- 2011-03-21 CR CR20110152A patent/CR20110152A/es unknown
-
2012
- 2012-08-21 JP JP2012182330A patent/JP2013005805A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2012506695A5 (https=) | ||
| RU2650767C2 (ru) | Интерлейкин-13-связывающие белки | |
| CN113286814A (zh) | 多价调节性t细胞调节子 | |
| JP2008502366A5 (https=) | ||
| CN110105451B (zh) | IL-4Rα抗体及其用途 | |
| WO2022033538A1 (zh) | Il-11的抗体及其应用 | |
| AU2005229009A1 (en) | Monoclonal antibodies specific for human OX40L (CD 134L) | |
| CN104105704A (zh) | Il4/il13结合重复蛋白及用途 | |
| CN101522716A (zh) | 抗人il-4受体的高亲和力人抗体 | |
| CA2626214C (en) | Novel use of il-1beta compounds | |
| JP2013005805A (ja) | 改変された抗ｉｌ−１３抗体、組成物、方法、及び使用 | |
| CN101932935A (zh) | 用于炎性关节病抗白介素-17a治疗的关节破坏生物标记 | |
| JP2025532685A (ja) | Ｔｓｌｐ及びｉｌ４ｒを標的とする組換え二重特異性抗体 | |
| WO2019148405A1 (zh) | IL-4Rα抗体及其用途 | |
| KR102558891B1 (ko) | 항―ｉｌ４―ｉｌ１３ ２특이성 항체 | |
| CN106397591A (zh) | 骨关节炎治疗 | |
| WO2022186772A1 (en) | TREATMENT OF ATOPIC DERMATITIS EMPLOYING ANTI-IL-13Rα1 ANTIBODY OR BINDING FRAGMENT THEREOF | |
| WO2013103783A1 (en) | Murine il-13 antibodies | |
| AU2022229076A1 (en) | TREATMENT OF ATOPIC DERMATITIS EMPLOYING ANTI-IL-13Rα1 ANTIBODY OR BINDING FRAGMENT THEREOF | |
| JP5476310B2 (ja) | ｈＧＭ−ＣＳＦに結合するモノクローナル抗体および前記抗体を含む医薬組成物 | |
| EP4590692A1 (en) | Bi-specific agent for targeted plasma cell-depletion and treatment of anti-viral immunodeficiency | |
| TW202540182A (zh) | 用於治療代謝疾病之新穎抗體和抗體共軛體 | |
| WO2024028509A2 (en) | Treatment of an inflammation-associated disease in a patient expressing high chemerin level | |
| HK40123789A (zh) | 优化的抗tl1a抗体 | |
| HK40052681A (en) | Multivalent regulatory t cell modulators |