CO6341573A2 - Anticuerpos anti-il-13 modificados, composiciones, métodos y usos - Google Patents

Anticuerpos anti-il-13 modificados, composiciones, métodos y usos

Info

Publication number
CO6341573A2
CO6341573A2 CO11019113A CO11019113A CO6341573A2 CO 6341573 A2 CO6341573 A2 CO 6341573A2 CO 11019113 A CO11019113 A CO 11019113A CO 11019113 A CO11019113 A CO 11019113A CO 6341573 A2 CO6341573 A2 CO 6341573A2
Authority
CO
Colombia
Prior art keywords
human
bind
receptor
alpha
monoclonal antibodies
Prior art date
Application number
CO11019113A
Other languages
English (en)
Spanish (es)
Inventor
Ronald V Swanson
Ellen Chi
Hong Mimi Zhou
Yiqing Feng
Alexey V Teplyakov
Jill M Carton
Karyn T Oneil
Jill Giles-Komar
Linus Hyun
Juan C Almagro
Wendy Cordier
Johan Fransson
Shanrong Zhao
Golapan Raghunathan
Original Assignee
Centocor Ortho Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centocor Ortho Biotech Inc filed Critical Centocor Ortho Biotech Inc
Publication of CO6341573A2 publication Critical patent/CO6341573A2/es

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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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    • C—CHEMISTRY; METALLURGY
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    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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    • C07K—PEPTIDES
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    • C07K2317/565—Complementarity determining region [CDR]
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    • C07—ORGANIC CHEMISTRY
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    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
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    • G01N2333/52—Assays involving cytokines
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  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
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  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Rheumatology (AREA)
  • Psychiatry (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Addiction (AREA)
  • Endocrinology (AREA)
  • Hospice & Palliative Care (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
CO11019113A 2008-08-20 2011-02-17 Anticuerpos anti-il-13 modificados, composiciones, métodos y usos CO6341573A2 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9047208P 2008-08-20 2008-08-20
US9723208P 2008-09-16 2008-09-16

Publications (1)

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CO6341573A2 true CO6341573A2 (es) 2011-11-21

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CO11019113A CO6341573A2 (es) 2008-08-20 2011-02-17 Anticuerpos anti-il-13 modificados, composiciones, métodos y usos

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Country Link
US (2) US8399630B2 (https=)
EP (1) EP2328615A2 (https=)
JP (2) JP2012506695A (https=)
KR (1) KR20110043786A (https=)
CN (1) CN102264391A (https=)
AR (1) AR073088A1 (https=)
AU (1) AU2009283008A1 (https=)
BR (1) BRPI0917370A2 (https=)
CA (1) CA2734645A1 (https=)
CO (1) CO6341573A2 (https=)
CR (1) CR20110152A (https=)
EA (1) EA201170357A1 (https=)
EC (1) ECSP11010840A (https=)
IL (1) IL211087A0 (https=)
MX (1) MX2011001909A (https=)
NI (1) NI201100040A (https=)
NZ (1) NZ591098A (https=)
UY (1) UY32060A (https=)
WO (1) WO2010021874A2 (https=)
ZA (1) ZA201102081B (https=)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
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US7306925B2 (en) 2001-11-09 2007-12-11 Vanderbilt University Phage antibodies to radiation-inducible neoantigens
US7906102B2 (en) 2001-10-03 2011-03-15 Vanderbilt University Ligands to radiation-induced molecules
US8399630B2 (en) * 2008-08-20 2013-03-19 Centocor Ortho Biotech Inc. Engineered anti-IL-13 antibodies, compositions, methods and uses
GB0904214D0 (en) * 2009-03-11 2009-04-22 Ucb Pharma Sa Biological products
ES2826883T3 (es) * 2009-10-14 2021-05-19 Janssen Biotech Inc Métodos de maduración por afinidad de anticuerpos
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