JP2012505881A5 - - Google Patents

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Publication number
JP2012505881A5
JP2012505881A5 JP2011532053A JP2011532053A JP2012505881A5 JP 2012505881 A5 JP2012505881 A5 JP 2012505881A5 JP 2011532053 A JP2011532053 A JP 2011532053A JP 2011532053 A JP2011532053 A JP 2011532053A JP 2012505881 A5 JP2012505881 A5 JP 2012505881A5
Authority
JP
Japan
Prior art keywords
oxo
methyl
hydroquinazolin
dihydroquinazolin
dichlorophenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2011532053A
Other languages
English (en)
Japanese (ja)
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JP2012505881A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2008/079975 external-priority patent/WO2010056230A1/en
Publication of JP2012505881A publication Critical patent/JP2012505881A/ja
Publication of JP2012505881A5 publication Critical patent/JP2012505881A5/ja
Withdrawn legal-status Critical Current

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JP2011532053A 2008-10-15 2008-10-15 ステアロイル−ＣｏＡデサチュラーゼの阻害剤として使用するための３−ヒドロキナゾリン−４−オン誘導体 Withdrawn JP2012505881A (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2008/079975 WO2010056230A1 (en) 2008-10-15 2008-10-15 3-hydroquinazolin-4-one derivatives for use as stearoyl coa desaturase inhibitors

Publications (2)

Publication Number Publication Date
JP2012505881A JP2012505881A (ja) 2012-03-08
JP2012505881A5 true JP2012505881A5 (enExample) 2012-11-22

Family

ID=40749129

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011532053A Withdrawn JP2012505881A (ja) 2008-10-15 2008-10-15 ステアロイル−ＣｏＡデサチュラーゼの阻害剤として使用するための３−ヒドロキナゾリン−４−オン誘導体

Country Status (4)

Country Link
EP (1) EP2350029A1 (enExample)
JP (1) JP2012505881A (enExample)
CA (1) CA2740389A1 (enExample)
WO (1) WO2010056230A1 (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2012213080B2 (en) 2011-01-31 2014-03-27 Novartis Ag Novel heterocyclic derivatives
PL2771342T3 (pl) 2011-10-28 2016-11-30 Nowe pochodne puryny i ich zastosowanie w leczeniu chorób
BR112014026266A2 (pt) 2012-04-24 2017-06-27 Chugai Pharmaceutical Co Ltd derivado de quinazolidinadiona
KR20150003849A (ko) 2012-04-24 2015-01-09 추가이 세이야쿠 가부시키가이샤 퀴나졸린디온 유도체
AU2013364068B2 (en) * 2012-12-21 2016-10-20 Gilead Calistoga Llc Substituted pyrimidine aminoalkyl-quinazolones as phosphatidylinositol 3-kinase inhibitors
CN105829285A (zh) * 2013-10-23 2016-08-03 中外制药株式会社 喹唑啉酮和异喹啉酮衍生物
PL3292116T3 (pl) 2015-02-02 2022-02-21 Valo Health, Inc. 3-arylo-4-amidobicykliczne kwasy [4,5,0]hydroksamowe jako inhibitory hdac
US10183934B2 (en) 2015-02-02 2019-01-22 Forma Therapeutics, Inc. Bicyclic [4,6,0] hydroxamic acids as HDAC inhibitors
US10555935B2 (en) 2016-06-17 2020-02-11 Forma Therapeutics, Inc. 2-spiro-5- and 6-hydroxamic acid indanes as HDAC inhibitors
CN110099898B (zh) 2016-10-24 2023-07-25 优曼尼蒂治疗公司 化合物及其用途
WO2018129403A1 (en) 2017-01-06 2018-07-12 Yumanity Therapeutics Methods for the treatment of neurological disorders
CA3083000A1 (en) 2017-10-24 2019-05-02 Yumanity Therapeutics, Inc. Compounds and uses thereof
CA3094527A1 (en) 2018-03-23 2019-09-26 Yumanity Therapeutics, Inc. Compounds and uses thereof
KR20220007845A (ko) 2019-01-24 2022-01-19 유마니티 테라퓨틱스, 인크. 화합물 및 이의 용도
EA202192047A1 (ru) 2019-11-13 2021-12-08 Юманити Терапьютикс, Инк. Соединения и их применение
IN202011027502A (enExample) * 2020-06-29 2021-12-31 Council Scient Ind Res

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2020073A1 (en) * 1989-07-03 1991-01-04 Eric E. Allen Substituted quinazolinones as angiotensin ii antagonists
US6638937B2 (en) * 1998-07-06 2003-10-28 Bristol-Myers Squibb Co. Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists
US6894057B2 (en) * 2002-03-08 2005-05-17 Warner-Lambert Company Oxo-azabicyclic compounds
US20040142950A1 (en) * 2003-01-17 2004-07-22 Bunker Amy Mae Amide and ester matrix metalloproteinase inhibitors
CA2580857A1 (en) * 2004-09-20 2006-09-28 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors
DK1830869T3 (da) * 2004-12-24 2013-08-26 Spinifex Pharm Pty Ltd Fremgangsmåde til behandling eller profylakse
WO2006125180A1 (en) * 2005-05-19 2006-11-23 Xenon Pharmaceuticals Inc. Piperazine derivatives and their uses as therapeutic agents

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