JP2012505881A5 - - Google Patents

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Publication number
JP2012505881A5
JP2012505881A5 JP2011532053A JP2011532053A JP2012505881A5 JP 2012505881 A5 JP2012505881 A5 JP 2012505881A5 JP 2011532053 A JP2011532053 A JP 2011532053A JP 2011532053 A JP2011532053 A JP 2011532053A JP 2012505881 A5 JP2012505881 A5 JP 2012505881A5
Authority
JP
Japan
Prior art keywords
oxo
methyl
hydroquinazolin
dihydroquinazolin
dichlorophenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2011532053A
Other languages
English (en)
Japanese (ja)
Other versions
JP2012505881A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2008/079975 external-priority patent/WO2010056230A1/en
Publication of JP2012505881A publication Critical patent/JP2012505881A/ja
Publication of JP2012505881A5 publication Critical patent/JP2012505881A5/ja
Withdrawn legal-status Critical Current

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JP2011532053A 2008-10-15 2008-10-15 ステアロイル−ＣｏＡデサチュラーゼの阻害剤として使用するための３−ヒドロキナゾリン−４−オン誘導体 Withdrawn JP2012505881A (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2008/079975 WO2010056230A1 (en) 2008-10-15 2008-10-15 3-hydroquinazolin-4-one derivatives for use as stearoyl coa desaturase inhibitors

Publications (2)

Publication Number Publication Date
JP2012505881A JP2012505881A (ja) 2012-03-08
JP2012505881A5 true JP2012505881A5 (enExample) 2012-11-22

Family

ID=40749129

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011532053A Withdrawn JP2012505881A (ja) 2008-10-15 2008-10-15 ステアロイル−ＣｏＡデサチュラーゼの阻害剤として使用するための３−ヒドロキナゾリン−４−オン誘導体

Country Status (4)

Country Link
EP (1) EP2350029A1 (enExample)
JP (1) JP2012505881A (enExample)
CA (1) CA2740389A1 (enExample)
WO (1) WO2010056230A1 (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX343706B (es) 2011-01-31 2016-11-18 Novartis Ag Derivados heterocíclicos novedosos.
PT2771342T (pt) 2011-10-28 2016-08-17 Novartis Ag Derivados de purina e o seu uso no tratamento de doença
CA2871237A1 (en) 2012-04-24 2013-10-31 Chugai Seiyaku Kabushiki Kaisha Benzamide derivative
AR090835A1 (es) 2012-04-24 2014-12-10 Chugai Pharmaceutical Co Ltd Derivados de quinazolindiona
AU2013364068B2 (en) * 2012-12-21 2016-10-20 Gilead Calistoga Llc Substituted pyrimidine aminoalkyl-quinazolones as phosphatidylinositol 3-kinase inhibitors
US10005739B2 (en) 2013-10-23 2018-06-26 Chugai Seiyaku Kabushiki Kaisha Quinazolinone and isoquinolinone derivative
PL3292116T3 (pl) 2015-02-02 2022-02-21 Valo Health, Inc. 3-arylo-4-amidobicykliczne kwasy [4,5,0]hydroksamowe jako inhibitory hdac
TW201636329A (zh) 2015-02-02 2016-10-16 佛瑪治療公司 作為ｈｄａｃ抑制劑之雙環［４，６，０］異羥肟酸
EP3472131B1 (en) 2016-06-17 2020-02-19 Forma Therapeutics, Inc. 2-spiro-5- and 6-hydroxamic acid indanes as hdac inhibitors
JP2019533022A (ja) 2016-10-24 2019-11-14 ユマニティ セラピューティクス，インコーポレーテッド 化合物及びその使用
EP3566055B1 (en) 2017-01-06 2025-03-12 Janssen Pharmaceutica NV Scd inhibitor for the treatment of neurological disorders
CA3083000A1 (en) 2017-10-24 2019-05-02 Yumanity Therapeutics, Inc. Compounds and uses thereof
WO2019183587A1 (en) 2018-03-23 2019-09-26 Yumanity Therapeutics, Inc. Compounds and uses thereof
WO2020154571A1 (en) 2019-01-24 2020-07-30 Yumanity Therapeutics, Inc. Compounds and uses thereof
EA202192047A1 (ru) 2019-11-13 2021-12-08 Юманити Терапьютикс, Инк. Соединения и их применение
IN202011027502A (enExample) * 2020-06-29 2021-12-31 Council Scient Ind Res

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2020073A1 (en) * 1989-07-03 1991-01-04 Eric E. Allen Substituted quinazolinones as angiotensin ii antagonists
US6638937B2 (en) * 1998-07-06 2003-10-28 Bristol-Myers Squibb Co. Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists
US6894057B2 (en) * 2002-03-08 2005-05-17 Warner-Lambert Company Oxo-azabicyclic compounds
US20040142950A1 (en) * 2003-01-17 2004-07-22 Bunker Amy Mae Amide and ester matrix metalloproteinase inhibitors
BRPI0515482A (pt) * 2004-09-20 2008-07-22 Xenon Pharmaceuticals Inc derivados heterocìclicos e seus usos como agentes terapêuticos
WO2006066361A1 (en) * 2004-12-24 2006-06-29 The University Of Queensland Method of treatment or prophylaxis
WO2006125180A1 (en) * 2005-05-19 2006-11-23 Xenon Pharmaceuticals Inc. Piperazine derivatives and their uses as therapeutic agents

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