JP2022534979A5 - - Google Patents

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Publication number
JP2022534979A5
JP2022534979A5 JP2021570866A JP2021570866A JP2022534979A5 JP 2022534979 A5 JP2022534979 A5 JP 2022534979A5 JP 2021570866 A JP2021570866 A JP 2021570866A JP 2021570866 A JP2021570866 A JP 2021570866A JP 2022534979 A5 JP2022534979 A5 JP 2022534979A5
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JP
Japan
Prior art keywords
dioxopiperidine
carboxamide
isoindoline
oxo
trifluoro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2021570866A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022534979A (ja
JP7496838B2 (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/035043 external-priority patent/WO2020243379A1/en
Publication of JP2022534979A publication Critical patent/JP2022534979A/ja
Publication of JP2022534979A5 publication Critical patent/JP2022534979A5/ja
Priority to JP2024086242A priority Critical patent/JP2024123001A/ja
Application granted granted Critical
Publication of JP7496838B2 publication Critical patent/JP7496838B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2021570866A 2019-05-31 2020-05-29 置換１－オキソ－イソインドリン－５－カルボキサミド化合物、その組成物、およびそれによる治療方法 Active JP7496838B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024086242A JP2024123001A (ja) 2019-05-31 2024-05-28 置換１－オキソ－イソインドリン－５－カルボキサミド化合物、その組成物、およびそれによる治療方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962855619P 2019-05-31 2019-05-31
US62/855,619 2019-05-31
PCT/US2020/035043 WO2020243379A1 (en) 2019-05-31 2020-05-29 Substituted 1-oxo-isoindoline-5-carboxamide compounds, compositions thereof, and methods of treatment therewith

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024086242A Division JP2024123001A (ja) 2019-05-31 2024-05-28 置換１－オキソ－イソインドリン－５－カルボキサミド化合物、その組成物、およびそれによる治療方法

Publications (3)

Publication Number Publication Date
JP2022534979A JP2022534979A (ja) 2022-08-04
JP2022534979A5 true JP2022534979A5 (enExample) 2023-05-30
JP7496838B2 JP7496838B2 (ja) 2024-06-07

Family

ID=73551319

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021570866A Active JP7496838B2 (ja) 2019-05-31 2020-05-29 置換１－オキソ－イソインドリン－５－カルボキサミド化合物、その組成物、およびそれによる治療方法
JP2024086242A Pending JP2024123001A (ja) 2019-05-31 2024-05-28 置換１－オキソ－イソインドリン－５－カルボキサミド化合物、その組成物、およびそれによる治療方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2024086242A Pending JP2024123001A (ja) 2019-05-31 2024-05-28 置換１－オキソ－イソインドリン－５－カルボキサミド化合物、その組成物、およびそれによる治療方法

Country Status (19)

Country Link
US (2) US11306101B2 (enExample)
EP (1) EP3976595A4 (enExample)
JP (2) JP7496838B2 (enExample)
KR (2) KR102913106B1 (enExample)
CN (4) CN114957212B (enExample)
AR (1) AR119057A1 (enExample)
AU (1) AU2020282748A1 (enExample)
BR (1) BR112021022758A2 (enExample)
CA (1) CA3136753A1 (enExample)
CL (1) CL2021003134A1 (enExample)
CO (1) CO2021015624A2 (enExample)
IL (1) IL288278B2 (enExample)
MX (1) MX2021014350A (enExample)
MY (1) MY208545A (enExample)
PE (1) PE20220569A1 (enExample)
SG (1) SG11202112872YA (enExample)
TW (2) TWI851729B (enExample)
WO (1) WO2020243379A1 (enExample)
ZA (1) ZA202109003B (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102913106B1 (ko) 2019-05-31 2026-01-19 셀진 코포레이션 치환된 1-옥소-이소인돌린-5-카르복스아미드 화합물, 그의 조성물 및 그를 사용한 치료 방법
MX2023004374A (es) * 2020-10-14 2023-07-06 C4 Therapeutics Inc Ligandos tricíclicos para la degradación de la familia ikaros 2 o la familia ikaros 4.
CN112679421A (zh) * 2021-01-04 2021-04-20 都创(上海)医药科技股份有限公司 一种(r)-3-氯吡啶基-2-三氟乙胺盐酸盐的合成方法
AU2022207648A1 (en) 2021-01-13 2023-07-27 Monte Rosa Therapeutics Ag Isoindolinone compounds
CN118019534A (zh) * 2021-05-06 2024-05-10 细胞基因公司 使用n-((r)-1-(3-氯吡啶-2-基)-2,2,2-三氟乙基)-2-((s)-2,6-二氧代哌啶-3-基)-1-氧代异吲哚啉-5-甲酰胺的治疗方法
CA3221549A1 (en) * 2021-06-08 2022-12-15 Liqiang Fu Isoindolinone compounds, and uses thereof
CN115504963A (zh) * 2021-06-22 2022-12-23 苏州开拓药业股份有限公司 一种c-Myc蛋白降解剂
US12122764B2 (en) 2021-12-22 2024-10-22 Gilead Sciences, Inc. IKAROS zinc finger family degraders and uses thereof
WO2023178181A1 (en) 2022-03-17 2023-09-21 Gilead Sciences, Inc. Ikaros zinc finger family degraders and uses thereof
EP4540240A1 (en) * 2022-06-16 2025-04-23 Monte Rosa Therapeutics AG Molecular glue degraders and methods of using the same
EP4540238A1 (en) * 2022-06-16 2025-04-23 Monte Rosa Therapeutics AG Molecular glue degraders and methods of using the same
WO2024027694A1 (zh) * 2022-08-01 2024-02-08 苏州开拓药业股份有限公司 一种蛋白降解剂
JP2025541841A (ja) * 2022-12-07 2025-12-23 ハンジョウ グルバイオ ファーマシューティカル カンパニー リミテッド オキソイソインドール－５－カルボキサミド系化合物またはその塩、溶媒和物の結晶形または無定形
JP2025541840A (ja) * 2022-12-07 2025-12-23 ハンジョウ グルバイオ ファーマシューティカル カンパニー リミテッド 固体分散体、その製造方法と使用
PL249026B1 (pl) * 2022-12-09 2026-02-23 Univ Mikolaja Kopernika W Toruniu Pochodna azetydyno-2,4-dionu, sposób jej otrzymywania i zastosowanie

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030045552A1 (en) 2000-12-27 2003-03-06 Robarge Michael J. Isoindole-imide compounds, compositions, and uses thereof
US7091353B2 (en) 2000-12-27 2006-08-15 Celgene Corporation Isoindole-imide compounds, compositions, and uses thereof
UA91560C2 (ru) 2005-08-31 2010-08-10 Селджин Корпорэйшн Соединения ряда изоиндолимидов, их композиция и применение
CL2007002513A1 (es) 2006-08-30 2008-04-04 Celgene Corp Soc Organizada Ba Compuestos derivados de isoindolina sustituidos, compuestos intermediarios; composicion farmaceutica; y uso en el tratamiento y prevencion de enfermedades tales como cancer, dolor, degeneracion macular, entre otras.
US8877780B2 (en) * 2006-08-30 2014-11-04 Celgene Corporation 5-substituted isoindoline compounds
ZA200901078B (en) * 2006-08-30 2010-06-30 Celgene Corp 5-substituted isoindoline compounds
US9499514B2 (en) 2014-07-11 2016-11-22 Celgene Corporation Antiproliferative compounds and methods of use thereof
WO2017007612A1 (en) * 2015-07-07 2017-01-12 Dana-Farber Cancer Institute, Inc. Methods to induce targeted protein degradation through bifunctional molecules
WO2017024318A1 (en) 2015-08-06 2017-02-09 Dana-Farber Cancer Institute, Inc. Targeted protein degradation to attenuate adoptive t-cell therapy associated adverse inflammatory responses
WO2017024317A2 (en) * 2015-08-06 2017-02-09 Dana-Farber Cancer Institute, Inc. Methods to induce targeted protein degradation through bifunctional molecules
KR102913106B1 (ko) 2019-05-31 2026-01-19 셀진 코포레이션 치환된 1-옥소-이소인돌린-5-카르복스아미드 화합물, 그의 조성물 및 그를 사용한 치료 방법

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